Journey information
Overview: Santorini (Island) to Madrid flight
Flights from Santorini (Island) to Madrid depart on average 19 times per day, taking around 5h 5m. Cheap flight tickets for this journey start at £74 if you book in advance.
The earliest flight runs at 00:20, the last at 23:55. The fastest flight covers the 2568 km distance in 6h 0m. August is the cheapest month to fly.
Distance 2568 km |
Average flight duration 5h 5m |
Cheapest ticket price £74 |
Flights per day 19 |
Fastest flight 6h 0m |
First flight 0:20 |
Last flight 23:55 |
Cheapest Month Aug |
Cheapest Day Wed |
High Season Jul - Sept |
Low Season Jan - Mar |
Busiest Day Sun |
Least Busy Day Sat |
Best time to book 42 days |
The cheapest and fastest flights from Santorini (Island) to Madrid
Cheapest price
£152
Average price
£200
Fastest journey
6 h
Average duration
7 h 50 m
Flights per day
11
Distance
2568 km
The best way to find a cheap flight ticket from Santorini (Island) to Madrid is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Santorini (Island) to Madrid will cost around £200 if you buy it on the day, but you can find cheap flight tickets today for only £152.
To travel from Santorini (Island) to Madrid you need to make at least one change.
A3351 · A37006:007h00Santorini (Thira) National Airport12:00Madrid Barajas Airport£1521One-way1 change
A3361 · A370022:0015h00Santorini (Thira) National Airport12:00Madrid Barajas Airport£1521One-way1 change
A3351 · A37406:0012h30Santorini (Thira) National Airport17:30Madrid Barajas Airport£1811One-way1 change
A3353 · A37408:2510h05Santorini (Thira) National Airport17:30Madrid Barajas Airport£1811One-way1 change
A3349 · A37409:209h10Santorini (Thira) National Airport17:30Madrid Barajas Airport£1811One-way1 change
A3357 · A374012:306h00Santorini (Thira) National Airport17:30Madrid Barajas Airport£2861One-way1 change
A3355 · A374011:356h55Santorini (Thira) National Airport17:30Madrid Barajas Airport£2861One-way1 change
A3351 · A37006:007h00Santorini (Thira) National Airport12:00Madrid Barajas Airport£1521One-way1 change
A3349 · A37409:209h10Santorini (Thira) National Airport17:30Madrid Barajas Airport£1811One-way1 change
A3353 · A37408:2510h05Santorini (Thira) National Airport17:30Madrid Barajas Airport£1811One-way1 change
Live departures
Santorini (Island) to Madrid flight times
The table below shows live departures for Santorini (Island) to Madrid flights for tomorrow, Tuesday 12 May. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
![]() | 3:00 Santorini (Island) | 7h00 | 10:00 Madrid | 0 changesdirect | |
![]() | 4:00 Santorini (Island) | 7h05 | 11:05 Madrid | 0 changesdirect | |
![]() | 9:55 Santorini (Island) | 6h30 | 16:25 Madrid | 0 changesdirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
How far in advance should I book flight tickets from Santorini (Island) to Madrid?
Compare prices and tickets Santorini (Island) to Madrid by flight
Compare flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Santorini (Island) to Madrid flights with Omio?
Why book with Omio vs Aegean Airlines?
- Compare with other providers: On Omio, you can not only buy tickets for Aegean Airlines, but also compare tickets for the likes of Iberia, Air Europa, Eurowings or Vueling to find the best option for your trip from Santorini (Island) to Madrid.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Edreams, Kayak or Skyscanner?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Iberia, Air Europa, Eurowings or Vueling to find the best option for your trip from Santorini (Island) to Madrid.
Airlines: Aegean Airlines, Iberia, Air Europa, Eurowings, Vueling, Edelweiss Air, Iberia Express, Air France, Lufthansa from Santorini (Island) to MadridFind the best flights between Santorini (Island) to Madrid with Omio's travel partners Aegean Airlines, Iberia, Air Europa, Eurowings, Vueling, Edelweiss Air, Iberia Express, Air France, Lufthansa from £74. We can find you the best deals, schedules and tickets when comparing and booking the best trip.
Air France
Lufthansa
Aegean Airlines
Iberia
Air Europa
Eurowings
Vueling
Iberia Express
Edelweiss Air
FAQs: Santorini (Island) to Madrid flights
Find answers to the most common questions about traveling from Santorini (Island) to Madrid by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

popular airports
Important Stations and Airports in Santorini (Island) and Madrid
- Free Wi-Fi available throughout the airport.
- Shops in all terminals, including duty-free and fashion brands.
- Parking available at all terminals, approximately 2.5€ per hour.
- Available outside the terminal.
- Ramps, assistance.
- Available throughout the airport.
- Yes
- Lounges available in all terminals, including VIP lounges.
- Located in Terminal 1, 2, and 4.
- Metro: Line 8
- Bus: Lines 101, 200, Exprés-203
- Train: Cercanías C1, C10
Most popular flights from Santorini (Island)
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