Journey information
Overview: Santorini (Island) to Madrid flight
Flights from Santorini (Island) to Madrid depart on average 19 times per day, taking around 4h 55m. Cheap flight tickets for this journey start at £93 if you book in advance.
The earliest flight runs at 00:20, the last at 23:55. The fastest flight covers the 2568 km distance in 6h 0m. March is the cheapest month to fly.
Distance 2568 km |
Average flight duration 4h 55m |
Cheapest ticket price £93 |
Flights per day 19 |
Fastest flight 6h 0m |
Cheapest month to travel March |
First flight 00:20 |
Last flight 23:55 |
The cheapest and fastest flights from Santorini (Island) to Madrid
Cheapest price
£133
Average price
£549
Fastest journey
6 h
Average duration
18 h 55 m
Flights per day
3
Distance
2568 km
The best way to find a cheap flight ticket from Santorini (Island) to Madrid is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Santorini (Island) to Madrid will cost around £549 if you buy it on the day, but you can find cheap flight tickets today for only £133.
Of the 3 flights that leave Santorini (Island) for Madrid every day 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct flights cover the 2568 km distance in an average of 18 h 55 m but if you time it right, some flights will get you there in just 6 h .
The slowest flights will take 1 d 14 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Live departures
Santorini (Island) to Madrid flight times
The table below shows live departures for Santorini (Island) to Madrid flights for tomorrow, Wednesday 25 March. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
![]() | 04:35 Santorini (Island) | 11h50 | 16:25 Madrid | 0 changesdirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
How far in advance should I book flight tickets from Santorini (Island) to Madrid?
Compare prices and tickets Santorini (Island) to Madrid by flight
Compare flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Santorini (Island) to Madrid flights with Omio?
Why book with Omio vs Aegean Airlines?
- Compare with other providers: On Omio, you can not only buy tickets for Aegean Airlines, but also compare tickets for the likes of Iberia, Air Europa, Eurowings or Vueling Airlines to find the best option for your trip from Santorini (Island) to Madrid.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Edreams, Kayak or Skyscanner?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Iberia, Air Europa, Eurowings or Vueling Airlines to find the best option for your trip from Santorini (Island) to Madrid.
Airlines: Aegean Airlines, Iberia, Air Europa, Eurowings, Vueling Airlines, Edelweiss Air, Iberia Express, Air France, Lufthansa from Santorini (Island) to MadridFind the best flights between Santorini (Island) to Madrid with Omio's travel partners Aegean Airlines, Iberia, Air Europa, Eurowings, Vueling Airlines, Edelweiss Air, Iberia Express, Air France, Lufthansa from £93. We can find you the best deals, schedules and tickets when comparing and booking the best trip.
Air France
Lufthansa
Aegean Airlines
Iberia
Air Europa
Eurowings
Vueling Airlines
Iberia Express
Edelweiss Air
FAQs: Santorini (Island) to Madrid flights
Find answers to the most common questions about traveling from Santorini (Island) to Madrid by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

popular airports
Important Stations and Airports in Santorini (Island) and Madrid
- Free Wi-Fi available throughout the airport.
- Shops in all terminals, including duty-free and fashion brands.
- Parking available at all terminals, approximately 2.5€ per hour.
- Available outside the terminal.
- Ramps, assistance.
- Available throughout the airport.
- Yes
- Lounges available in all terminals, including VIP lounges.
- Located in Terminal 1, 2, and 4.
- Metro: Line 8
- Bus: Lines 101, 200, Exprés-203
- Train: Cercanías C1, C10
Most popular flights from Santorini (Island)
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