- Must visit
Vatican Museums
World-renowned Vatican collections with Raphael Rooms and the Sistine Chapel, essential for art and Church history.
Cheapest price
£105
Average price
£127
Fastest journey
19 h 35 m
Average duration
19 h 54 m
Buses per day
34
Distance
923 km
The best way to find a cheap coach ticket from Prague to Rome is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Prague to Rome will cost around £127 if you buy it on the day, but you can find cheap coach tickets today for only £105.
Of the 34 buses that leave Prague for Rome every day 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct buses cover the 923 km distance in an average of 19 h 54 m but if you time it right, some buses will get you there in just 19 h 35 m .
The slowest buses will take 20 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Prague to Rome among Omio's users. If you are prioritising price take the flight with prices starting from £24. For those with little time consider booking a flight which can get you there in 3h 36m. In case you are seeking to minimise your carbon footprint the coach is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a flight costs an average of £24, and a coach costs an average of £65.
Distance: 923 km
| Coach | Most popular Flight |
|---|---|
£93 Average Price | £77 Average Price Cheapest |
15h 10m Average total duration 14h 40m Onboard + 30m Additional time* | 5h 36m Average total duration Fastest 3h 36m Onboard + 2h 0m Additional time* |
0.9 - 2.3kg CO2 emissions Lowest | 2.8 - 5.5kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The table below shows live departures for Prague to Rome coaches for tomorrow, Thursday 27 August. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 2:30 Prague, Central Train Station | 20h30 | 23:00 Roma, Autostazione Tiburtina | 1 change | |
FlixBus · FlixBus · FlixBus | 5:50 Prague, Central Train Station | 27h40 | 9:30 Roma, Autostazione Tiburtina | 2 changes | |
FlixBus · FlixBus · FlixBus | 7:55 Praha, Na Knížecí | 23h10 | 7:05 Roma, Autostazione Tiburtina | 2 changes | |
FlixBus · FlixBus · FlixBus | 8:30 Praha, Roztyly | 25h00 | 9:30 Roma, Autostazione Tiburtina | 2 changes | |
FlixBus · FlixBus · FlixBus | 9:00 Prague, Central Train Station | 21h10 | 6:10 Roma, Autostazione Tiburtina | 2 changes | |
FlixBus · FlixBus · FlixBus | 9:40 Praha, Na Knížecí | 23h50 | 9:30 Roma, Autostazione Tiburtina | 2 changes | |
FlixBus · FlixBus · FlixBus | 9:40 Praha, Na Knížecí | 26h35 | 12:15 Roma, Autostazione (Metro Anagnina) | 2 changes | |
FlixBus · FlixBus | 11:00 Praha, ÚAN Florenc | 20h05 | 7:05 Roma, Autostazione Tiburtina | 1 change | |
FlixBus · FlixBus · FlixBus | 11:00 Praha, Roztyly | 27h45 | 14:45 Roma, Autostazione Tiburtina | 2 changes | |
FlixBus · FlixBus | 11:15 Prague, Central Train Station | 19h50 | 7:05 Roma, Autostazione Tiburtina | 1 change | |
FlixBus · FlixBus | 12:50 Praha, M. Horákové (Hradčanská) | 24h30 | 13:20 Roma, Autostazione Tiburtina | 1 change | |
FlixBus · FlixBus | 12:50 Praha, ÚAN Florenc | 20h40 | 9:30 Roma, Autostazione Tiburtina | 1 change | |
FlixBus · FlixBus · FlixBus | 12:50 Praha, M. Horákové (Hradčanská) | 26h15 | 15:05 Roma, Autostazione (Metro Anagnina) | 2 changes | |
FlixBus · FlixBus | 13:05 Prague, Central Train Station | 20h25 | 9:30 Roma, Autostazione Tiburtina | 1 change | |
FlixBus · FlixBus · FlixBus | 14:30 Praha, Černý Most | 24h35 | 15:05 Roma, Autostazione (Metro Anagnina) | 2 changes | |
FlixBus · FlixBus | 14:30 Praha, Černý Most | 22h50 | 13:20 Roma, Autostazione Tiburtina | 1 change | |
FlixBus · FlixBus · FlixBus | 15:05 Praha, Zličín | 22h15 | 13:20 Roma, Autostazione Tiburtina | 2 changes | |
FlixBus · FlixBus · FlixBus | 16:00 Praha, ÚAN Florenc | 20h15 | 12:15 Roma, Autostazione (Metro Anagnina) | 2 changes | |
FlixBus · FlixBus · FlixBus | 16:15 Prague, Central Train Station | 20h00 | 12:15 Roma, Autostazione (Metro Anagnina) | 2 changes | |
FlixBus · FlixBus · FlixBus | 17:15 Praha, ÚAN Florenc | 21h50 | 15:05 Roma, Autostazione (Metro Anagnina) | 2 changes | |
FlixBus | 17:30 Praha, ÚAN Florenc | 21h15 | 14:45 Roma, Autostazione Tiburtina | 0 changesdirect | |
FlixBus · FlixBus · FlixBus | 17:30 Prague, Central Train Station | 21h35 | 15:05 Roma, Autostazione (Metro Anagnina) | 2 changes | |
FlixBus · FlixBus | 17:45 Prague, Central Train Station | 24h05 | 17:50 Roma, Autostazione (Metro Anagnina) | 1 change | |
FlixBus | 17:45 Prague, Central Train Station | 21h00 | 14:45 Roma, Autostazione Tiburtina | 0 changesdirect | |
FlixBus · FlixBus | 17:45 Praha, Na Knížecí | 19h35 | 13:20 Roma, Autostazione Tiburtina | 1 change | |
FlixBus · FlixBus · FlixBus | 17:45 Praha, Na Knížecí | 21h20 | 15:05 Roma, Autostazione (Metro Anagnina) | 2 changes | |
FlixBus · FlixBus | 18:45 Praha, Roztyly | 22h40 | 17:25 Roma, Autostazione Tiburtina | 1 change | |
FlixBus · FlixBus · FlixBus | 19:25 Praha, Zličín | 23h20 | 18:45 Roma, Autostazione Tiburtina | 2 changes | |
FlixBus · FlixBus | 21:25 Praha, ÚAN Florenc | 20h25 | 17:50 Roma, Autostazione (Metro Anagnina) | 1 change | |
FlixBus · FlixBus | 21:25 Praha, ÚAN Florenc | 20h00 | 17:25 Roma, Autostazione Tiburtina | 1 change | |
FlixBus · FlixBus · FlixBus | 21:50 Praha, Na Knížecí | 25h10 | 23:00 Roma, Autostazione Tiburtina | 2 changes | |
FlixBus · FlixBus | 21:55 Praha, ÚAN Florenc | 22h40 | 20:35 Roma, Autostazione Tiburtina | 1 change | |
FlixBus · FlixBus · FlixBus | 22:25 Praha, M. Horákové (Hradčanská) | 24h35 | 23:00 Roma, Autostazione Tiburtina | 2 changes | |
FlixBus · FlixBus · FlixBus | 23:50 Prague, Central Train Station | 22h00 | 21:50 Roma, Autostazione Tiburtina | 2 changes | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Prague to Rome run on average 38 times per day, taking around 14h 40m. Cheap bus tickets for this journey start at £65 but you can travel from only £24 by flight.
There are 2 coaches per day. The earliest coach runs at 00:10, the last at 23:50. The fastest coach covers the 923 km distance in 20h 5m.
Distance 923 km |
Average bus duration 14h 40m |
Cheapest ticket price £65 |
Buses per day 38 |
Direct buses 2 |
Fastest bus 20h 5m |
First bus 0:10 |
Last bus 23:50 |
Cheapest Month Mar |
Cheapest Day Mon |
High Season Jul - Sept |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Fri |
Best time to book 84 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-renowned Vatican collections with Raphael Rooms and the Sistine Chapel, essential for art and Church history.
Superb Capitoline collections on Michelangelo's square, showcasing ancient sculpture, bronzes, and Rome's civic history.
Outstanding gallery in a villa setting, celebrated for Bernini sculptures and masterpieces by Caravaggio and Raphael.
Baroque square with fountains and lively street life, ideal for people-watching and a classic Rome atmosphere.
Famous staircase linking Piazza di Spagna to Trinità dei Monti, beloved for city scenes and elegant surroundings.
Bohemian quarter of lanes, piazzas, and nightlife, popular for evening strolls, local character, and riverside charm.
Roman pasta with guanciale, egg yolk, Pecorino Romano and black pepper. A city icon prized for its rich sauce and no cream tradition.
Pasta in a sharp, savoury sauce of guanciale, tomato and Pecorino Romano. A classic Roman favourite with roots in local trattoria cooking.
Simple Roman pasta made with Pecorino Romano and black pepper. It shows the city’s love of bold flavour from few ingredients.
Michelin-starred restaurant by the Colosseum serving refined Roman cuisine in an elegant setting. Best for a fine-dining splurge.
Historic Trastevere trattoria known for classic Roman pasta and warm old-school rooms. A dependable choice for traditional local dishes.
Long-running Testaccio restaurant specialising in Roman quinto quarto and pasta. Informal, authentic and popular with locals and visitors.
Moderate for a major Western European capital. Hotels in central areas are pricey, but dining and public transport are often cheaper than in Paris or London.
Service is often included or covered by a coperto. Rounding up or leaving 5-10% is appreciated in restaurants. In cafés, small change is enough; taxis are usually rounded up.
Official public transport app
Via Marsala, Rome -> Piazza Venezia, Rome
Find answers to the most common questions about traveling from Prague to Rome by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Prague to Rome buses use the Praha, Hlavní Nádraží to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Prague and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Food options include: Cafes and vending machines available.
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Ticket office support is available at Roma, Autostazione Tiburtina.
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Here are some other resources that might have the information you need