- Must visit
Swiss Museum of Transport
Major transport museum with trains, planes, automobiles and interactive exhibits. Excellent for families and anyone curious about mobility.
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The cheapest and fastest coaches from Prague to Lucerne
Showing times, prices and bookable tickets for 26 Oct
Cheapest price on 26 Oct
£61
Average ticket price on 26 Oct
£69
Fastest journey on 26 Oct
9 h 30 m
Average journey duration on 26 Oct
16 h 13 m
Buses on 26 Oct
11
Distance
562 km
Cheap tickets
The best way to find a cheap coach ticket from Prague to Lucerne is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Prague to Lucerne will cost around £69 if you buy it on the day, but you can find cheap coach tickets today for only £61.
Fast coaches
On Mon 26 Oct, we found 11 buses from Prague to Lucerne, including 1 direct services.
These direct buses cover the 562 km distance in an average of 16 h 13 m but if you time it right, some buses will get you there in just 9 h 30 m .
The slowest buses will take 21 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus · FlixBus · FlixBus17:1023h15Praha, Roztyly16:25Luzern, Landenburgstrasse (Busparkplatz)£611One-way2 changes- FlixBus · FlixBus · FlixBus17:3022h55Prague, Central Train Station16:25Luzern, Landenburgstrasse (Busparkplatz)£611One-way2 changes
- FlixBus · FlixBus · FlixBus22:2523h10Praha, M. Horákové (Hradčanská)21:35Luzern, Landenburgstrasse (Busparkplatz)£621One-way2 changes
- FlixBus · FlixBus · FlixBus23:5021h45Prague, Central Train Station21:35Luzern, Landenburgstrasse (Busparkplatz)£621One-way2 changes
- FlixBus · FlixBus · FlixBus19:2521h00Praha, Zličín16:25Luzern, Landenburgstrasse (Busparkplatz)£621One-way2 changes
00024021:009h30Praha, ÚAN Florenc6:30Luzern, Landenburgstrasse (Busparkplatz)£801One-way0 changes- FlixBus · FlixBus9:0016h25Prague, Central Train Station1:25Luzern, Landenburgstrasse (Busparkplatz)£761One-way1 change
- FlixBus · FlixBus8:4516h40Praha, ÚAN Florenc1:25Luzern, Landenburgstrasse (Busparkplatz)£761One-way1 change
- FlixBus · FlixBus · FlixBus7:5517h30Praha, Na Knížecí1:25Luzern, Landenburgstrasse (Busparkplatz)£681One-way2 changes
- FlixBus · FlixBus · FlixBus19:2521h00Praha, Zličín16:25Luzern, Landenburgstrasse (Busparkplatz)£621One-way2 changes
Journey information
Overview: Bus from Prague to Lucerne
Czechia
Switzerland
Buses from Prague to Lucerne run on average 6 times per day, taking around 13h 18m. Cheap bus tickets for this journey start at £34 if you book in advance.
There are 1 coaches per day. The earliest coach runs at 01:30, the last at 23:50. The fastest coach covers the 562 km distance in 9h 30m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 562 km |
Average bus duration 13h 18m |
Cheapest ticket price £34 |
Buses per day 6 |
Direct buses 1 |
Fastest bus 9h 30m |
First bus 1:30 |
Last bus 23:50 |
Cheapest Month Mar |
Cheapest Day Fri |
High Season Jul - Sept |
Low Season Jan - Mar |
Busiest Day Sat |
Least Busy Day Wed |
Best time to book 28 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Frequently asked questions about your Prague to Lucerne trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Prague to Lucerne.
Cheap coach tickets from Prague to Lucerne can start from as little as £34 when you book in advance. The average coach ticket price for Prague to Lucerne is £64; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest coach from Prague to Lucerne leaves at 1:30. Plan your trip with the Journey Planner from Omio.
The latest coach from Prague to Lucerne leaves at 23:50.
Yes, there are 1 direct coaches a day from Prague to Lucerne with ČSAD Tišnov. Schedules can vary on holidays or weekends with fewer direct coaches.
Live departures
Prague to Lucerne bus times
The table below shows live departures for Prague to Lucerne coaches for today, Sunday 25 October. You can also manually refresh the results below to see updated coach journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
| 000240 | 21:00 Praha, ÚAN Florenc | 9h30 | 6:30 Luzern, Landenburgstrasse (Busparkplatz) | 0 changesdirect | |
| FlixBus · FlixBus | 21:25 Praha, ÚAN Florenc | 13h55 | 11:20 Luzern, Landenburgstrasse (Busparkplatz) | 1 change | |
| FlixBus · FlixBus | 21:50 Praha, Na Knížecí | 13h30 | 11:20 Luzern, Landenburgstrasse (Busparkplatz) | 1 change | |
| Monday 26 October | |||||
| FlixBus · FlixBus | 6:20 Praha, Černý Most | 22h00 | 4:20 Luzern, Landenburgstrasse (Busparkplatz) | 1 change | |
| FlixBus · FlixBus · FlixBus | 7:55 Praha, Na Knížecí | 17h30 | 1:25 Luzern, Landenburgstrasse (Busparkplatz) | 2 changes | |
| FlixBus · FlixBus | 8:45 Praha, ÚAN Florenc | 16h40 | 1:25 Luzern, Landenburgstrasse (Busparkplatz) | 1 change | |
| FlixBus · FlixBus | 9:00 Prague, Central Train Station | 16h25 | 1:25 Luzern, Landenburgstrasse (Busparkplatz) | 1 change | |
| FlixBus · FlixBus · FlixBus | 15:10 Praha, ÚAN Florenc | 21h55 | 13:05 Luzern, Landenburgstrasse (Busparkplatz) | 2 changes | |
| FlixBus · FlixBus · FlixBus | 17:10 Praha, Roztyly | 23h15 | 16:25 Luzern, Landenburgstrasse (Busparkplatz) | 2 changes | |
| FlixBus · FlixBus · FlixBus | 17:30 Prague, Central Train Station | 22h55 | 16:25 Luzern, Landenburgstrasse (Busparkplatz) | 2 changes | |
Find all the dates and times for this journey
Why should you book Prague to Lucerne coaches with Omio?
FlixBus as well as ČSAD Tišnov offer coaches services from Prague to Lucerne.
Omio is an official ticket reseller for all your travel options from Prague to Lucerne.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of ČSAD Tišnov to find the best option for your trip from Prague to Lucerne.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Prague to Lucerne.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Prague to Lucerne.
Bus providers: FlixBus, ČSAD Tišnov from Prague to LucerneYou can travel by bus between Prague to Lucerne with FlixBus, ČSAD Tišnov for as low as £34. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
11h 20m
Cheapest FlixBus Price
£34
FlixBus frequency
5 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
ČSAD Tišnov
About
ČSAD Tišnov is a bus company based in the Czech Republic, with a history dating back to 1949 as part of the national enterprise ČSAD. It became an independent state enterprise in 1991 and was privatized in 1994. The company operates a significant number of regional bus routes, particularly in the Brno area as part of the IDS JMK integrated transport system, and also provides long-distance and international coach services to countries like Switzerland and Slovakia. ČSAD Tišnov also offers bus rentals for various occasions. Their fleet includes buses from manufacturers such as Irisbus, Iveco, SOR, MAN, Mercedes-Benz, and Neoplan. Beyond passenger transport, ČSAD Tišnov also provides vehicle repair and maintenance services, including being an authorized service partner for MAN, NEOPLAN, IVECO, and SOR.
Luggage & cancellation policy
Average ČSAD Tišnov Duration
9h 30m
Cheapest ČSAD Tišnov Price
£72
ČSAD Tišnov frequency
1 a day
Luggage included
One carry-on bag up to 10kg (55x40x20) and one checked bag up to 20kg (70x50x30).
Additional luggage
5€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
Amenities on board the bus
Wifi
Seat reservation
Toilets
Accessibility
Assistance; Priority seating; Assistance with boarding and alighting.
Bikes
Bikes are allowed; reservation recommended.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.
Companies, tickets, and onboard amenities between Prague and Lucerne
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a coach from Prague to Lucerne, you can count on FlixBus, ČSAD Tišnov for the best way to get you to Lucerne. You can also check all possible coach companies who offer a service between Prague and Lucerne and compare the amenities they offer before buying a coach ticket.
Yes, there are bathrooms on board the coach from Prague to Lucerne for coach company FlixBus, ČSAD Tišnov.
Yes, the following accessibility options are available when taking the coach from Prague to Lucerne:
- ČSAD Tišnov
- Assistance
- Priority seating
- Assistance with boarding and alighting.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Whether you can cancel your coach ticket from Prague to Lucerne depends on the coach companies:
- ČSAD Tišnov
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the coach with coach company {providersWithBike}.
No, there is no food available to purchase on board the coach from Prague to Lucerne.
Yes, the following luggage options are included when booking a coach ticket from Prague to Lucerne:
- ČSAD Tišnov
- One carry-on bag up to 10kg (55x40x20) and one checked bag up to 20kg (70x50x30).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a coach ticket from Prague to Lucerne:
- ČSAD Tišnov
- 5€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the coach from Prague to Lucerne. The following conditions apply:
- ČSAD Tišnov
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the coach from Prague to Lucerne with the following coach company: FlixBus, ČSAD Tišnov
Yes, there are USB plugs on board the coach from Prague to Lucerne with the following coach company: FlixBus.
Yes, there is Wifi on board the coach from Prague to Lucerne with the following coach company: FlixBus, ČSAD Tišnov.
Complete guide to Lucerne
Things to do in Lucerne
Discover the best of Lucerne — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lucerne trip today.
- Recommended
Kunstmuseum Luzern
Art museum at KKL with modern and classical exhibitions. A strong choice for thoughtful shows in a prominent lakeside cultural venue.
- Recommended
Sammlung Rosengart
Museum dedicated to Pablo Picasso’s later years, showing works and photographs in a central old-town building near the Reuss.
- Must visit
Altstadt
Car-free old town area with painted facades, fountains and lively lanes. Ideal for wandering, shopping and seeing Lucerne beyond the postcard icons.
- Recommended
Nationalquai
Lakeside promenade and district with grand villas, gardens and mountain views. Perfect for an easy walk away from the busiest centre streets.
- Recommended
Dietschiberg
Hilltop viewpoint above Lucerne reached by funicular, with broad panoramas over the city, lake and surrounding mountains.
- Vegetarian
Käsefondue
A rich cheese fondue often made with Swiss cheeses and white wine. A classic shared Alpine dish widely enjoyed in Lucerne, especially in colder months.
- Gluten-free
Rösti
Swiss rösti of grated potatoes fried until crisp and often served as a side or main. It is a staple across Central Switzerland and common in Lucerne inns.
- Vegetarian
Älplermagronen
Pasta-like dumplings from Central Switzerland, traditionally served with cheese, onions or apple sauce. A hearty rustic dish linked to Alpine farming traditions.
Restaurant Oliveira's
Refined dining venue by the lake with seasonal cuisine, polished service and elegant surroundings suited to a special meal.
Restaurant Fritschi
Well-known old-town Swiss restaurant serving fondue, raclette and hearty regional food in a lively, traditional setting.
Rössli Gourmet & Bar
Casual Lucerne institution popular for crisp potato rösti with varied toppings, offering a relaxed and reliable Swiss meal near the centre.
Swiss franc (CHF)
Lucerne is pricier than most European cities, with high hotel, dining and local transport costs, especially in peak tourist season.
Average meal costs
- Budget
- CHF 15-25 for fast food or a simple meal.
- Mid-range
- CHF 35-60 per person for a restaurant meal.
- Fine dining
- CHF 90+ per person for upscale restaurants.
- Coffee
- CHF 4.50-6 for a cappuccino.
Tipping culture
Service is usually included. Round up or leave 5-10% for excellent service in restaurants. Round up small amounts for taxis and cafés.
SBB Mobile
Get the appOfficial public transport app
Prices
- Single ticket
- CHF 3.80
- Day pass
- /null
To the city centre
Lucerne railway station -> Kapellbrücke, Lucerne
- Distance
- 0.7 km
- Travel time
- 10 min
- Buy zone tickets in the Passepartout network via SBB Mobile or from machines before boarding. Lucerne local travel is covered by Zone 10 fares.
- Card and contactless payment are commonly available at ticket machines and in official ticket apps. Check your ticket before travel, as Swiss public transport uses proof-of-payment inspections.
Best day trips from Lucerne by bus
The most popular day trips by bus from Lucerne are Zurich, Bern, Basel and Interlaken. Find out what you can do in these day trip destinations and how to book your bus from Lucerne on Omio.
Day trip from Lucerne to Zurich by bus
Why visit Zurich for the day?
Zurich combines a global financial role with a calm lakeside setting and a well-kept Altstadt. It is known for banking and shopping, but also for art, river bathing and a distinctly orderly Swiss feel.
How to get from Lucerne to Zurich by bus?
The earliest coach runs at 00:02, the last at 23:58.
Day trip from Lucerne to Bern by bus
Why visit Bern for the day?
Bern is Switzerland’s capital, known for its sandstone Old City, arcades and the Aare around its centre. It combines medieval character with a calm, everyday feel and a strong link to Albert Einstein.
How to get from Lucerne to Bern by bus?
The earliest coach runs at 00:02, the last at 23:33.
Day trip from Lucerne to Basel by bus
Why visit Basel for the day?
Basel is known for its art museums, Rhine setting and well-kept old town. On Switzerland’s northern border, it feels both historic and distinctly international.
How to get from Lucerne to Basel by bus?
The earliest coach runs at 00:04, the last at 23:54.
Day trip from Lucerne to Interlaken by bus
Why visit Interlaken for the day?
Interlaken sits between Lake Thun and Lake Brienz and is known as a gateway to the Jungfrau region. Its grand old hotels, riverfront setting and steady outdoor buzz give the town a polished but relaxed Alpine feel.
How to get from Lucerne to Interlaken by bus?
There are 2 coaches per day. The earliest coach runs at 00:05, the last at 23:57. The fastest coach covers the 53 km distance in 1h 9m.
FAQs: Prague to Lucerne coach
Find answers to the most common questions about traveling from Prague to Lucerne by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Lucerne, this guide helps you travel smarter and with confidence.
It's helpful to compare your options as there are 3 ways to travel between Prague and Lucerne including taking a coach, train and flight.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
popular bus stations
Important Stations and Airports in Prague and Lucerne
Most Prague to Lucerne buses use the Praha, ÚAN Florenc to Luzern, Landenburgstrasse (Busparkplatz) station pair. Use this guide to compare Prague and Lucerne bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Prague
Arrival bus stations in Lucerne
Which Prague station do buses to Lucerne leave from?
Buses from Prague to Lucerne leave from Praha, ÚAN Florenc. The station is 1 km from Prague city centre at Krizikova 6, 186 00 Praha 8-Karlin, Czechia.
Praha, ÚAN FlorencKrizikova 6, 186 00 Praha 8-Karlin, Czechia
City-centre transport
Getting to Praha, ÚAN Florenc from Prague city centre
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Bus207, *888 · 9m · £2 · every ~14 min
Tram3, 24, 31, 92, 94 · 13m · £2 · every ~24 min
SubwayB · 2m · £2 · every ~27 min
Praha, ÚAN Florenc bus station facilities and services
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food and drink
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Tickets and information
Ticket office support is available at Praha, ÚAN Florenc.
Parking, taxis and toilets
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Hlavní NádražíWilsonova 300/8, 110 00 Praha 1, Czech Republic
City-centre transport
Getting to Praha, Hlavní Nádraží from Prague city centre
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
TrainRj, 600, 602, 604, 606, 608, 610, 612, 614, 616, 618, 670, 674, 676, 678, 680, 682, 684, 686, 688, 690, 692, 694, 696, 698, 2474, Re · 8m · £1 · every ~3 min
Nj · 8m · £13
Bus478 · 5m
Tram17, 93 · 10m · £2 · every ~23 min
17, 93 · 12m · £2 · every ~23 min
SubwayC · 5m · £2 · every ~29 min
Praha, Hlavní Nádraží bus station facilities and services
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food and drink
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Tickets and information
Ticket office support is available at Praha, Hlavní Nádraží.
Parking, taxis and toilets
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, Na KnížecíNa Knizeci, Prague, Czech Republic
City-centre transport
Getting to Praha, Na Knížecí from Prague city centre
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Bus907, 908 · 16m · £2 · every ~1 min
N109, 084, N1759, N1309, 853, 109 · 20m · £1 · every ~1 min
Tram12, 15, 20 · 11m · £2 · every ~33 min
Praha, Na Knížecí bus station facilities and services
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility and WC.
Food and drink
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the entrance.
Parking, taxis and toilets
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Which Lucerne station do buses from Prague arrive at?
Buses from Prague to Lucerne arrive at Luzern, Landenburgstrasse (Busparkplatz). Luzern, Landenburgstrasse (Busparkplatz) is 1 km from Lucerne city centre.
Luzern, Landenburgstrasse (Busparkplatz)Landenbergstrasse, 6005 Luzern, Switzerland
City-centre transport
Getting to Luzern, Landenburgstrasse (Busparkplatz) from Lucerne city centre
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Luzern, Landenburgstrasse (Busparkplatz) bus station facilities and services
Luzern, Landenburgstrasse (Busparkplatz) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Luzern, Landenburgstrasse (Busparkplatz). ATMs are available at Luzern, Landenburgstrasse (Busparkplatz).
Tickets and information
Ticket office support is available at Luzern, Landenburgstrasse (Busparkplatz).
Parking, taxis and toilets
Available at Luzern, Landenburgstrasse (Busparkplatz): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Luzern, Landenburgstrasse (Busparkplatz): Accessible for individuals with reduced mobility.
Bus stations for Prague to Lucerne
Check bus stations information for Prague and Lucerne, including where buses depart and arrive on this route.
When departing from Prague , you have various coach station options to start your route from including Praha, ÚAN Florenc, Praha, Hlavní Nádraží, Praha, Na Knížecí, Praha, Letiště Václava Havla, Praha, Zličín, Praha, Černý Most, Praha, M. Horákové (Hradčanská), Praha, Roztyly . When arriving in Lucerne , you can end your route in coach stations like Luzern, Landenburgstrasse (Busparkplatz).Passengers board the coach most frequently from Praha, ÚAN Florenc, which is located around 1 km away from the city centre, and they get off the coach at Luzern, Landenburgstrasse (Busparkplatz), located 1 away from the city centre.
More options for your journey from Prague to Lucerne
Here are some other resources that might have the information you need
Most popular buses to and from Lucerne and Prague
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