FlixBus17:0520h40Roma, Autostazione Tiburtina13:45Prague, Central Train Station£1111One-way0 changes
FlixBus17:0520h50Roma, Autostazione Tiburtina13:55Praha, ÚAN Florenc£1111One-way0 changes
FlixBus · FlixBus · FlixBus17:2522h45Roma, Autostazione (Metro Anagnina)16:10Praha, Černý Most£1151One-way2 changes
FlixBus · FlixBus21:0020h30Roma, Autostazione Tiburtina17:30Prague, Central Train Station£1151One-way1 change
FlixBus · FlixBus21:0020h45Roma, Autostazione Tiburtina17:45Praha, ÚAN Florenc£1151One-way1 change
FlixBus · FlixBus · FlixBus17:2519h55Roma, Autostazione (Metro Anagnina)13:20Prague, Central Train Station£1161One-way2 changes
FlixBus · FlixBus · FlixBus17:2520h05Roma, Autostazione (Metro Anagnina)13:30Praha, ÚAN Florenc£1161One-way2 changes
FlixBus · FlixBus13:0520h20Roma, Autostazione (Metro Anagnina)9:25Praha, ÚAN Florenc£1451One-way1 change
FlixBus · FlixBus22:5520h25Roma, Autostazione Tiburtina19:20Prague, Central Train Station£1371One-way1 change
FlixBus · FlixBus21:0020h30Roma, Autostazione Tiburtina17:30Prague, Central Train Station£1151One-way1 change
Travel Information
Compare train, coach and flight for Rome to Prague
The cheapest option from Rome to Prague is flight, with an average price of £82. Omio recommends booking the flight, as it is the most popular option from Rome to Prague among Omio users. If you are seeking to minimise your carbon footprint, the bus is your best option, as it emits only 0.9 - 2.3kg.
Distance: 923 km
Compare bus with
| Coach | Most popular Flight | Train |
|---|---|---|
£82 Average Price Cheapest option | £109 Average Price | £214 Average Price |
20h 23m Average total duration 19h 53m Onboard + 30m Additional time* | 5h 50m Average total duration Fastest option 2h 50m Onboard + 3h 0m Additional time* | 18h 2m Average total duration 17h 32m Onboard + 30m Additional time* |
0.9 - 2.3kg CO2 emissions Lowest | 2.8 - 5.5kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Rome to Prague bus times
The table below shows live departures for Rome to Prague coaches for tomorrow, Friday 10 July. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 7:30 Roma, Autostazione Tiburtina | 22h15 | 5:45 Praha, ÚAN Florenc | 1 change | |
FlixBus · FlixBus · FlixBus | 9:30 Roma, Autostazione Tiburtina | 23h25 | 8:55 Praha, Na Knížecí | 2 changes | |
FlixBus · FlixBus | 9:30 Roma, Autostazione Tiburtina | 21h30 | 7:00 Prague, Central Train Station | 1 change | |
FlixBus · FlixBus · FlixBus | 9:30 Roma, Autostazione Tiburtina | 28h30 | 14:00 Prague, Central Train Station | 2 changes | |
FlixBus · FlixBus · FlixBus | 9:30 Roma, Autostazione Tiburtina | 22h00 | 7:30 Praha, M. Horákové (Hradčanská) | 2 changes | |
FlixBus · FlixBus | 9:30 Roma, Autostazione Tiburtina | 21h40 | 7:10 Praha, ÚAN Florenc | 1 change | |
FlixBus · FlixBus · FlixBus | 10:40 Roma, Autostazione Tiburtina | 24h50 | 11:30 Praha, Zličín | 2 changes | |
FlixBus · FlixBus · FlixBus | 11:40 Roma, Autostazione Tiburtina | 22h55 | 10:35 Prague, Central Train Station | 2 changes | |
FlixBus · FlixBus · FlixBus | 12:00 Roma, Autostazione (Metro Anagnina) | 23h45 | 11:45 Praha, Na Knížecí | 2 changes | |
FlixBus · FlixBus · FlixBus | 12:10 Roma, Autostazione Tiburtina | 24h00 | 12:10 Prague, Central Train Station | 2 changes | |
FlixBus · FlixBus · FlixBus | 12:20 Roma, Autostazione Tiburtina | 25h00 | 13:20 Praha, Roztyly | 2 changes | |
FlixBus · FlixBus · FlixBus | 12:20 Roma, Autostazione Tiburtina | 23h25 | 11:45 Praha, Na Knížecí | 2 changes | |
FlixBus · FlixBus · FlixBus | 12:20 Roma, Autostazione Tiburtina | 25h25 | 13:45 Praha, Černý Most | 2 changes | |
FlixBus · FlixBus | 12:20 Roma, Autostazione Tiburtina | 21h05 | 9:25 Praha, ÚAN Florenc | 1 change | |
FlixBus · FlixBus · FlixBus | 12:45 Roma, Autostazione (Metro Anagnina) | 25h00 | 13:45 Praha, Černý Most | 2 changes | |
FlixBus · FlixBus · FlixBus | 12:45 Roma, Autostazione (Metro Anagnina) | 24h35 | 13:20 Praha, Roztyly | 2 changes | |
FlixBus · FlixBus | 13:05 Roma, Autostazione (Metro Anagnina) | 20h20 | 9:25 Praha, ÚAN Florenc | 1 change | |
FlixBus · FlixBus · FlixBus | 13:05 Roma, Autostazione (Metro Anagnina) | 21h30 | 10:35 Prague, Central Train Station | 2 changes | |
FlixBus · FlixBus | 17:00 Roma, Autostazione Tiburtina | 27h00 | 20:00 Prague, Central Train Station | 1 change | |
FlixBus · FlixBus · FlixBus | 17:05 Roma, Autostazione Tiburtina | 23h25 | 16:30 Praha, Roztyly | 2 changes | |
FlixBus | 17:05 Roma, Autostazione Tiburtina | 20h40 | 13:45 Prague, Central Train Station | 0 changesdirect | |
FlixBus · FlixBus · FlixBus | 17:05 Roma, Autostazione Tiburtina | 25h25 | 18:30 Praha, Zličín | 2 changes | |
FlixBus | 17:05 Roma, Autostazione Tiburtina | 20h50 | 13:55 Praha, ÚAN Florenc | 0 changesdirect | |
FlixBus · FlixBus · FlixBus | 17:05 Roma, Autostazione Tiburtina | 24h30 | 17:35 Praha, M. Horákové (Hradčanská) | 2 changes | |
FlixBus · FlixBus · FlixBus | 17:05 Roma, Autostazione Tiburtina | 23h05 | 16:10 Praha, Černý Most | 2 changes | |
FlixBus · FlixBus · FlixBus | 17:25 Roma, Autostazione (Metro Anagnina) | 19h55 | 13:20 Prague, Central Train Station | 2 changes | |
FlixBus · FlixBus · FlixBus | 17:25 Roma, Autostazione (Metro Anagnina) | 24h10 | 17:35 Praha, M. Horákové (Hradčanská) | 2 changes | |
FlixBus · FlixBus · FlixBus | 17:25 Roma, Autostazione (Metro Anagnina) | 22h45 | 16:10 Praha, Černý Most | 2 changes | |
FlixBus · FlixBus · FlixBus | 17:25 Roma, Autostazione (Metro Anagnina) | 20h05 | 13:30 Praha, ÚAN Florenc | 2 changes | |
FlixBus · FlixBus · FlixBus | 17:25 Roma, Autostazione (Metro Anagnina) | 25h45 | 19:10 Praha, Na Knížecí | 2 changes | |
FlixBus · FlixBus | 21:00 Roma, Autostazione Tiburtina | 20h30 | 17:30 Prague, Central Train Station | 1 change | |
FlixBus · FlixBus · FlixBus | 21:00 Roma, Autostazione Tiburtina | 22h10 | 19:10 Praha, Na Knížecí | 2 changes | |
FlixBus · FlixBus | 21:00 Roma, Autostazione Tiburtina | 20h45 | 17:45 Praha, ÚAN Florenc | 1 change | |
FlixBus · FlixBus · FlixBus | 21:00 Roma, Autostazione Tiburtina | 26h55 | 23:55 Prague, Central Train Station | 2 changes | |
FlixBus · FlixBus | 22:55 Roma, Autostazione Tiburtina | 20h25 | 19:20 Prague, Central Train Station | 1 change | |
FlixBus · FlixBus | 22:55 Roma, Autostazione Tiburtina | 20h35 | 19:30 Praha, ÚAN Florenc | 1 change | |
FlixBus · FlixBus · FlixBus | 22:55 Roma, Autostazione Tiburtina | 24h00 | 22:55 Praha, Na Knížecí | 2 changes | |
FlixBus · FlixBus · FlixBus | 23:05 Roma, Autostazione Tiburtina | 23h30 | 22:35 Praha, Roztyly | 2 changes | |
FlixBus · FlixBus | 23:05 Roma, Autostazione Tiburtina | 22h25 | 21:30 Praha, Černý Most | 1 change | |
FlixBus · FlixBus | 23:05 Roma, Autostazione Tiburtina | 21h50 | 20:55 Praha, ÚAN Florenc | 1 change | |
FlixBus · FlixBus · FlixBus | 23:05 Roma, Autostazione Tiburtina | 27h20 | 2:25 Prague, Central Train Station | 2 changes | |
FlixBus · FlixBus · FlixBus | 23:35 Roma, Autostazione (Metro Anagnina) | 27h40 | 3:15 Prague, Central Train Station | 2 changes | |
FlixBus · FlixBus · FlixBus | 23:50 Roma, Autostazione Tiburtina | 27h25 | 3:15 Prague, Central Train Station | 2 changes | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Prague by train, coach or flight
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
10 Jul
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14 Jul
15 Jul
16 Jul
17 Jul
18 Jul
19 Jul
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22 Jul
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30 Jul
Why should you book Rome to Prague coaches with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Rome to Prague.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Rome to Prague.
Journey information
Overview: Bus from Rome to Prague
Typically, there are 38 buses per day from Rome to Prague, including 2 direct buses, taking around 19h 53m. Cheap bus tickets for this journey start at £50 but you can travel from only £14 by flight.
The earliest coach runs at 00:10, the last at 23:55. The fastest coach covers the 923 km distance in 20h 10m.
Distance 923 km |
Average bus duration 19h 53m |
Lowest ticket price £50 |
Buses per day 38 |
Direct buses 2 |
Fastest bus 20h 10m |
First bus 0:10 |
Last bus 23:55 |
Cheapest Month May |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 28 days |
Bus providers: FlixBus from Rome to PragueYou can travel by bus between Rome to Prague with FlixBus for as low as £14. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Rome to Prague coach
Find answers to the most common questions about traveling from Rome to Prague by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Important Stations and Airports in Rome and Prague
Most Rome to Prague buses use the Roma, Autostazione Tiburtina to Praha, Hlavní Nádraží station pair, with some services arriving at Praha, ÚAN Florenc. Use this guide to compare Rome and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Getting to Roma, Autostazione Tiburtina from Rome city centre
Getting to Roma, Autostazione (Metro Anagnina) from Rome city centre
Getting to Ciampino, Aeroporto Internazionale di Roma–Ciampino "G. B. Pastine" from Rome city centre
Which Prague station do buses from Rome arrive at?
Getting to Praha, Hlavní Nádraží from Prague city centre
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží bus station facilities and services
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food and drink
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Tickets and information
Ticket office support is available at Praha, Hlavní Nádraží.
Parking, taxis and toilets
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Getting to Praha, ÚAN Florenc from Prague city centre
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc bus station facilities and services
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food and drink
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Tickets and information
Ticket office support is available at Praha, ÚAN Florenc.
Parking, taxis and toilets
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Getting to Praha, Na Knížecí from Prague city centre
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí bus station facilities and services
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility and WC.
Food and drink
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the entrance.
Parking, taxis and toilets
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Most popular bus connections from Rome
More options for your journey from Rome to Prague
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