FlixBus9:1512h15Düsseldorf, ZOB am Hbf21:30Praha, ÚAN Florenc£491One-way0 changes
FlixBus9:1511h55Düsseldorf, ZOB am Hbf21:10Praha, Na Knížecí£491One-way0 changes
FlixBus · FlixBus3:4513h50Düsseldorf, ZOB am Hbf17:35Praha, M. Horákové (Hradčanská)£521One-way1 change
FlixBus · FlixBus14:0012h50Düsseldorf, ZOB am Hbf2:50Prague, Central Train Station£521One-way1 change
FlixBus · FlixBus1:3012h00Düsseldorf, ZOB am Hbf13:30Praha, ÚAN Florenc£541One-way1 change
(Amsterdam -> Prague)18:509h58Düsseldorf, ZOB am Hbf4:48Praha, ÚAN Florenc£671One-way0 changes
FlixBus23:3010h40Düsseldorf, ZOB am Hbf10:10Praha, ÚAN Florenc£571One-way0 changes
FlixBus · FlixBus22:3511h30Düsseldorf, ZOB am Hbf10:05Praha, Na Knížecí£661One-way1 change
FlixBus7:3011h40Düsseldorf, ZOB am Hbf19:10Praha, Na Knížecí£601One-way0 changes
FlixBus7:1511h55Düsseldorf, ZOB am Hbf19:10Praha, ÚAN Florenc£601One-way0 changes
Travel Information
Compare train, coach and flight for Düsseldorf to Prague
The cheapest option from Düsseldorf to Prague is coach, with an average price of £42. Omio recommends booking the train, as it is the most popular option from Düsseldorf to Prague among Omio users. If you are seeking to minimise your carbon footprint, the train is your best option, as it emits only 0.2 - 0.5kg.
Distance: 553 km
Compare bus with
| Coach | Most popular Train | Flight |
|---|---|---|
£42 Average Price Cheapest option | £68 Average Price | £167 Average Price |
10h 36m Average total duration 10h 6m Onboard + 30m Additional time* | 9h 45m Average total duration 9h 15m Onboard + 30m Additional time* | 5h 7m Average total duration Fastest option 2h 7m Onboard + 3h 0m Additional time* |
0.6 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.3kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Düsseldorf to Prague bus times
The table below shows live departures for Düsseldorf to Prague coaches for today, Wednesday 8 July. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 22:35 Düsseldorf, ZOB am Hbf | 11h30 | 10:05 Praha, Na Knížecí | 1 change | |
FlixBus · FlixBus | 22:35 Düsseldorf, ZOB am Hbf | 12h45 | 11:20 Prague, Central Train Station | 1 change | |
FlixBus | 23:30 Düsseldorf, ZOB am Hbf | 10h40 | 10:10 Praha, ÚAN Florenc | 0 changesdirect | |
FlixBus · FlixBus | 23:30 Düsseldorf, ZOB am Hbf | 12h00 | 11:30 Prague, Central Train Station | 1 change | |
FlixBus · FlixBus | 23:59 Düsseldorf, ZOB am Hbf | 14h01 | 14:00 Prague, Central Train Station | 1 change | |
FlixBus · FlixBus | 1:30 Düsseldorf, ZOB am Hbf | 12h00 | 13:30 Praha, ÚAN Florenc | 1 change | |
FlixBus · FlixBus | 3:45 Düsseldorf, ZOB am Hbf | 13h50 | 17:35 Praha, M. Horákové (Hradčanská) | 1 change | |
FlixBus | 7:15 Düsseldorf, ZOB am Hbf | 11h55 | 19:10 Praha, ÚAN Florenc | 0 changesdirect | |
FlixBus · FlixBus | 7:15 Düsseldorf, ZOB am Hbf | 12h45 | 20:00 Praha, M. Horákové (Hradčanská) | 1 change | |
FlixBus | 7:30 Düsseldorf, ZOB am Hbf | 12h05 | 19:35 Praha, ÚAN Florenc | 0 changesdirect | |
FlixBus | 7:30 Düsseldorf, ZOB am Hbf | 11h40 | 19:10 Praha, Na Knížecí | 0 changesdirect | |
FlixTrain+ FlixBus | 8:38 Düsseldorf Hbf | 13h47 | 22:25 Praha, Černý Most | 1 change | |
FlixBus | 9:15 Düsseldorf, ZOB am Hbf | 12h15 | 21:30 Praha, ÚAN Florenc | 0 changesdirect | |
FlixBus | 9:15 Düsseldorf, ZOB am Hbf | 11h55 | 21:10 Praha, Na Knížecí | 0 changesdirect | |
FlixBus · FlixBus | 14:00 Düsseldorf, ZOB am Hbf | 12h50 | 2:50 Prague, Central Train Station | 1 change | |
FlixBus · FlixBus | 18:20 Düsseldorf, ZOB am Hbf | 13h10 | 7:30 Praha, M. Horákové (Hradčanská) | 1 change | |
FlixBus · FlixBus | 18:20 Düsseldorf, ZOB am Hbf | 12h35 | 6:55 Praha, ÚAN Florenc | 1 change | |
(Amsterdam -> Prague) | 18:50 Düsseldorf, ZOB am Hbf | 9h58 | 4:48 Praha, ÚAN Florenc | 0 changesdirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Düsseldorf to Prague by train, coach or flight
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
09 Jul
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17 Jul
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Why should you book Düsseldorf to Prague coaches with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Infobus to find the best option for your trip from Düsseldorf to Prague.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Düsseldorf to Prague.
Why book with Omio over Wanderu, Trainline or Busbud?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Düsseldorf to Prague.
ReviewsReviews for the bus trip from Düsseldorf to Prague

Journey information
Overview: Bus from Düsseldorf to Prague
Typically, there are 23 buses per day from Düsseldorf to Prague, including 6 direct buses, taking around 10h 6m. Cheap bus tickets for this journey start at £27 if you book in advance.
The earliest coach runs at 00:10, the last at 23:50. The fastest coach covers the 553 km distance in 9h 55m.
Distance 553 km |
Average bus duration 10h 6m |
Lowest ticket price £27 |
Buses per day 23 |
Direct buses 6 |
Fastest bus 9h 55m |
First bus 0:10 |
Last bus 23:50 |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Mon |
Best time to book 70 days |
Bus providers: FlixBus, BlaBlaCar, Infobus from Düsseldorf to PragueYou can travel by bus between Düsseldorf to Prague with FlixBus, BlaBlaCar, Infobus for as low as £27. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
BlaBlaCar
FAQs: Düsseldorf to Prague coach
Find answers to the most common questions about traveling from Düsseldorf to Prague by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Infobus
- 10€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Important Stations and Airports in Düsseldorf and Prague
Most Düsseldorf to Prague buses use the Düsseldorf, ZOB am Hbf to Praha, ÚAN Florenc station pair, with some services arriving at Praha, Hlavní Nádraží. Use this guide to compare Düsseldorf and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Düsseldorf station do buses to Prague leave from?
Getting to Düsseldorf, ZOB am Hbf from Düsseldorf city centre
Düsseldorf, ZOB am Hbf is 1 km from Düsseldorf city centre. Public transport options include:
Düsseldorf, ZOB am Hbf bus station facilities and services
Düsseldorf, ZOB am Hbf has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food and drink
Food options include: Cafeteria im ZOB (in the station), Brauerei Schumacher (0.5 km), Pizzeria Trattoria Romantica (0.7 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Tickets and information
Ticket office support is available at Düsseldorf, ZOB am Hbf.
Parking, taxis and toilets
Available at Düsseldorf, ZOB am Hbf: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Düsseldorf, ZOB am Hbf: Elevators, ramps.
Getting to Düsseldorf, Flughafen from Düsseldorf city centre
Which Prague station do buses from Düsseldorf arrive at?
Getting to Praha, ÚAN Florenc from Prague city centre
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc bus station facilities and services
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food and drink
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Tickets and information
Ticket office support is available at Praha, ÚAN Florenc.
Parking, taxis and toilets
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Getting to Praha, Hlavní Nádraží from Prague city centre
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží bus station facilities and services
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food and drink
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Tickets and information
Ticket office support is available at Praha, Hlavní Nádraží.
Parking, taxis and toilets
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Getting to Praha, Na Knížecí from Prague city centre
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí bus station facilities and services
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility and WC.
Food and drink
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the entrance.
Parking, taxis and toilets
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Most popular bus connections from Düsseldorf
More options for your journey from Düsseldorf to Prague
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