The cheapest and fastest coaches from Düsseldorf to Prague
Cheapest price
£38
Average price
£54
Fastest journey
7 h
Average duration
9 h 1 m
Buses per day
26
Distance
553 km
The best way to find a cheap coach ticket from Düsseldorf to Prague is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Düsseldorf to Prague will cost around £54 if you buy it on the day, but you can find cheap coach tickets today for only £38.
Of the 26 buses that leave Düsseldorf for Prague every day 10 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct buses cover the 553 km distance in an average of 9 h 1 m but if you time it right, some buses will get you there in just 7 h .
The slowest buses will take 10 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
(Amsterdam -> Prague)18:509h55Düsseldorf, ZOB am Hbf4:45Prague, Central Train Station£381One-way0 changes
(Amsterdam -> Prague)18:509h58Düsseldorf, ZOB am Hbf4:48Praha, ÚAN Florenc£381One-way0 changes
15:107h00Düsseldorf22:10Prague£401One-way0 changes
FlixBus7:3012h05Düsseldorf, ZOB am Hbf19:35Praha, ÚAN Florenc£501One-way0 changes
FlixBus9:1512h15Düsseldorf, ZOB am Hbf21:30Praha, ÚAN Florenc£501One-way0 changes
15:107h00Düsseldorf22:10Prague£401One-way0 changes
13:307h30Düsseldorf21:00Prague£581One-way0 changes
(Amsterdam -> Prague)18:509h55Düsseldorf, ZOB am Hbf4:45Prague, Central Train Station£381One-way0 changes
(Amsterdam -> Prague)18:509h58Düsseldorf, ZOB am Hbf4:48Praha, ÚAN Florenc£381One-way0 changes
FlixBus23:3010h40Düsseldorf, ZOB am Hbf10:10Praha, ÚAN Florenc£501One-way0 changes
Travel Information
Compare train, coach and flight for Düsseldorf to Prague
Omio recommends booking the train as it is the most popular option from Düsseldorf to Prague among Omio's users. If you are prioritising price take the coach with prices starting from £27. For those with little time consider booking a flight which can get you there in 2h 0m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a coach costs an average of £27, and a flight costs an average of £40.
Distance: 553 km
Compare bus with
| Coach | Most popular Train | Flight |
|---|---|---|
£44 Average Price Cheapest | £67 Average Price | £139 Average Price |
10h 24m Average total duration 9h 54m Onboard + 30m Additional time* | 9h 50m Average total duration 9h 20m Onboard + 30m Additional time* | 5h 0m Average total duration Fastest 2h 0m Onboard + 3h 0m Additional time* |
0.6 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.3kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Düsseldorf to Prague bus times
The table below shows live departures for Düsseldorf to Prague coaches for today, Wednesday 8 April. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
(Amsterdam -> Prague) | 16:50 Düsseldorf, ZOB am Hbf | 9h55 | 2:45 Prague, Central Train Station | 0 changesdirect | |
(Amsterdam -> Prague) | 16:50 Düsseldorf, ZOB am Hbf | 9h58 | 2:48 Praha, ÚAN Florenc | 0 changesdirect | |
FlixBus · FlixBus | 20:35 Düsseldorf, ZOB am Hbf | 12h45 | 9:20 Prague, Central Train Station | 1 change | |
FlixBus · FlixBus | 20:35 Düsseldorf, ZOB am Hbf | 11h30 | 8:05 Praha, Na Knížecí | 1 change | |
FlixBus | 21:30 Düsseldorf, ZOB am Hbf | 10h40 | 8:10 Praha, ÚAN Florenc | 0 changesdirect | |
FlixBus · FlixBus | 21:30 Düsseldorf, ZOB am Hbf | 12h30 | 10:00 Prague, Central Train Station | 1 change | |
FlixBus · FlixBus | 21:59 Düsseldorf, ZOB am Hbf | 14h01 | 12:00 Prague, Central Train Station | 1 change | |
FlixBus · FlixBus | 23:30 Düsseldorf, ZOB am Hbf | 12h00 | 11:30 Praha, ÚAN Florenc | 1 change | |
| Thursday 9 April | |||||
FlixBus · FlixBus | 5:15 Düsseldorf, ZOB am Hbf | 15h10 | 20:25 Praha, Černý Most | 1 change | |
FlixBus | 5:15 Düsseldorf, ZOB am Hbf | 11h55 | 17:10 Praha, ÚAN Florenc | 0 changesdirect | |
FlixBus | 5:30 Düsseldorf, ZOB am Hbf | 12h05 | 17:35 Praha, ÚAN Florenc | 0 changesdirect | |
FlixBus | 5:30 Düsseldorf, ZOB am Hbf | 11h40 | 17:10 Praha, Na Knížecí | 0 changesdirect | |
FlixTrain+ FlixBus | 6:38 Düsseldorf Hbf | 12h32 | 19:10 Praha, ÚAN Florenc | 1 change | |
FlixBus | 7:15 Düsseldorf, ZOB am Hbf | 12h15 | 19:30 Praha, ÚAN Florenc | 0 changesdirect | |
FlixBus · FlixBus | 7:15 Düsseldorf, ZOB am Hbf | 15h10 | 22:25 Prague, Central Train Station | 1 change | |
FlixBus | 7:15 Düsseldorf, ZOB am Hbf | 11h55 | 19:10 Praha, Na Knížecí | 0 changesdirect | |
FlixTrain+ FlixBus · FlixBus | 7:27 Düsseldorf Hbf | 14h58 | 22:25 Prague, Central Train Station | 2 changes | |
FlixTrain+ FlixBus · FlixBus | 7:27 Düsseldorf Hbf | 14h38 | 22:05 Praha, Na Knížecí | 2 changes | |
FlixBus · FlixBus | 12:00 Düsseldorf, ZOB am Hbf | 12h50 | 0:50 Prague, Central Train Station | 1 change | |
FlixBus · FlixBus | 14:45 Düsseldorf, ZOB am Hbf | 14h15 | 5:00 Prague, Central Train Station | 1 change | |
FlixBus · FlixBus | 16:20 Düsseldorf, ZOB am Hbf | 13h10 | 5:30 Praha, M. Horákové (Hradčanská) | 1 change | |
FlixBus · FlixBus | 16:20 Düsseldorf, ZOB am Hbf | 12h35 | 4:55 Praha, ÚAN Florenc | 1 change | |
FlixBus · FlixBus · FlixBus | 16:20 Düsseldorf, ZOB am Hbf | 14h10 | 6:30 Praha, Zličín | 2 changes | |
FlixBus · FlixBus | 16:20 Düsseldorf, ZOB am Hbf | 14h35 | 6:55 Praha, Na Knížecí | 1 change | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Düsseldorf to Prague by train, coach or flight
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
08 Apr
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Why should you book Düsseldorf to Prague coaches with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Infobus to find the best option for your trip from Düsseldorf to Prague.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Düsseldorf to Prague.
Why book with Omio over Wanderu, Trainline or Busbud?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Düsseldorf to Prague.
ReviewsReviews for the bus trip from Düsseldorf to Prague

Journey information
Overview: Bus from Düsseldorf to Prague
Buses from Düsseldorf to Prague run on average 23 times per day, taking around 9h 54m. Cheap bus tickets for this journey start at £27 if you book in advance.
There are 6 coaches per day. The earliest coach runs at 00:10, the last at 23:50. The fastest coach covers the 553 km distance in 9h 58m.
Distance 553 km |
Average bus duration 9h 54m |
Cheapest ticket price £27 |
Buses per day 23 |
Direct buses 6 |
Fastest bus 9h 58m |
First bus 0:10 |
Last bus 23:50 |
Bus providers: FlixBus, BlaBlaCar, Infobus from Düsseldorf to PragueYou can travel by bus between Düsseldorf to Prague with FlixBus, BlaBlaCar, Infobus for as low as £27. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
BlaBlaCar
FAQs: Düsseldorf to Prague coach
Find answers to the most common questions about traveling from Düsseldorf to Prague by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Infobus
- 10€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Important Stations and Airports in Düsseldorf and Prague
- 05:00-23:00
- Free Wi-Fi
- Cafeteria im ZOB (in the station)
- Brauerei Schumacher (0.5 km)
- Pizzeria Trattoria Romantica (0.7 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 725, 738, 752, 754, 834 Metro: U75, U78, U79 Train: S1, S6, S11
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
Most popular bus connections from Düsseldorf
More options for your journey from Düsseldorf to Prague
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