- Recommended
Schwarzenberg Palace
The city’s leading art museum in a noble palace, showing European works from medieval painting to the nineteenth century in elegant historic rooms.
Omio recommends booking the flight as it is the most popular option from Istanbul to Prague among Omio's users. If you are prioritising price take the coach with prices starting from £70. For those with little time consider booking a flight which can get you there in 6h 59m. The ticket price range depends on the travel mode: a coach costs an average of £70, and a flight costs an average of £44.
Distance: 1511 km
| Coach | Most popular Flight |
|---|---|
£92 Average Price Cheapest | £102 Average Price |
24h 17m Average total duration 23h 47m Onboard + 30m Additional time* | 9h 59m Average total duration Fastest 6h 59m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options |
The table below shows live departures for Istanbul to Prague coaches for today, Saturday 15 August. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 11:00 Istanbul, Buyuk Otogar (Esenler) | 34h50 | 20:50 Praha, ÚAN Florenc | 1 change | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Istanbul to Prague run on average 1 times per day, taking around 23h 47m. Cheap bus tickets for this journey start at £70 but you can travel from only £44 by flight.
The earliest coach runs at 11:00, the last at 21:10. The fastest coach covers the 1511 km distance in 34h 50m.
Distance 1511 km |
Average bus duration 23h 47m |
Cheapest ticket price £70 |
Buses per day 1 |
Fastest bus 34h 50m |
First bus 11:00 |
Last bus 21:10 |
Cheapest Month May |
Cheapest Day Thu |
High Season Oct - Dec |
Low Season Jul - Sept |
Busiest Day Thu |
Least Busy Day Fri |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
The city’s leading art museum in a noble palace, showing European works from medieval painting to the nineteenth century in elegant historic rooms.
A major modern and contemporary art venue with Czech and international works. The trade fair palace setting suits large exhibitions and bold installations.
A private museum focused on Czech and central European modern art. It combines strong permanent displays with temporary exhibitions in a central location.
The heart of historic Prague, filled with merchant houses, churches and lively public space. It is ideal for first-time visitors and evening atmosphere.
A broad boulevard of shops, hotels and major buildings. It is a useful base for city walks and an important setting in modern Czech history.
A landscaped hilltop park with orchards, paths and one of Prague’s finest sunset views. It feels local, relaxed and well away from the busiest crowds.
Slow-braised beef in a creamy root-vegetable sauce, usually with bread dumplings. A classic Czech Sunday dish strongly associated with Bohemian home cooking.
Roast pork with sauerkraut and bread or potato dumplings. It is one of the most traditional hearty Czech pub and family meals.
Goulash in the Czech style, usually beef, onions and paprika, often served with bread dumplings. A staple of Prague pubs and traditional kitchens.
Stylish restaurant focused on updated Czech cuisine and Czech wines, with a polished but relaxed atmosphere close to the city centre.
Well-known Lokál branch for Pilsner, svíčková and pub staples, with a busy modern beer-hall atmosphere in central Prague.
Long-established venue known for roast meats, Czech specialities and beer, with striking Art Nouveau interiors by Municipal House.
Moderate for Europe. Beer, casual meals and public transport are good value, but central hotels and tourist areas cost more than in many Central European cities.
Tip around 5-10% in restaurants if service is good, often by rounding up. Round up taxi fares. In cafés, small change or rounding up is usual.
Official public transport app
Praha hlavní nádraží -> Old Town Square, Prague
Find answers to the most common questions about traveling from Istanbul to Prague by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Istanbul to Prague buses use the Istanbul, Büyük Otogari (Esenler) to Praha, ÚAN Florenc station pair. Use this guide to compare Istanbul and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Istanbul, Büyük Otogari (Esenler) is 5 km from Istanbul city centre. Public transport options include:
Istanbul, Büyük Otogari (Esenler) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food options include: Cafeteria Terminal (in the station), Kebab Express (0.2 km), Simit Sarayı (0.3 km).
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Ticket office support is available at Istanbul, Büyük Otogari (Esenler).
Available at Istanbul, Büyük Otogari (Esenler): Parking, Taxis, WC.
Accessibility facilities are available at Istanbul, Büyük Otogari (Esenler): Elevators, ramps.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
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