- Must visit
Museo Nazionale del Paleolitico di Isernia
The National Palaeolithic Museum presents the famous prehistoric finds from La Pineta with clear displays on early human life in Molise.
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The cheapest and fastest trains from Rome to Isernia
Showing times, prices and bookable tickets for 09 Oct
Cheapest price on 09 Oct
£12
Average ticket price on 09 Oct
£25
Fastest journey on 09 Oct
2 h 5 m
Average journey duration on 09 Oct
2 h 11 m
Trains on 09 Oct
14
Distance
149 km
Cheap tickets
The best way to find a cheap train ticket from Rome to Isernia is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Rome to Isernia will cost around £25 if you buy it on the day, but you can find cheap train tickets today for only £12.
Fast trains
On Fri 09 Oct, we found 14 trains from Rome to Isernia, including 6 direct services.
These direct trains cover the 149 km distance in an average of 2 h 11 m but if you time it right, some trains will get you there in just 2 h 5 m .
The slowest trains will take 2 h 16 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Regionale 233659:072h08Rome Termini11:15Isernia station£121One-way0 changes- Regionale 2336914:352h05Rome Termini16:40Isernia station£121One-way0 changes
- Regionale 2336713:072h16Rome Termini15:23Isernia station£121One-way0 changes
- Regionale 2342517:382h14Rome Tiburtina19:52Isernia station£121One-way0 changes
- Regionale 233636:152h12Rome Termini8:27Isernia station£121One-way0 changes
- Regionale 2336914:352h05Rome Termini16:40Isernia station£121One-way0 changes
- Regionale 233659:072h08Rome Termini11:15Isernia station£121One-way0 changes
- Regionale 233636:152h12Rome Termini8:27Isernia station£121One-way0 changes
- Regionale 2342517:382h14Rome Tiburtina19:52Isernia station£121One-way0 changes
- Regionale 2336713:072h16Rome Termini15:23Isernia station£121One-way0 changes
Journey information
Overview: Train from Rome to Isernia
ItalyItaly
Trains from Rome to Isernia run on average 10 times per day, taking around 2h 48m. Cheap train tickets for this journey start at £12 but you can travel from only £4 by coach.
There are 5 trains per day. The earliest train runs at 04:50, the last at 23:56. The fastest train covers the 149 km distance in 1h 59m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Coach from £4
Distance 149 km |
Average train duration 2h 48m |
Cheapest ticket price £12 |
Trains per day 10 |
Direct trains 5 |
Fastest train 1h 59m |
First train 4:50 |
Last train 23:56 |
Cheapest Month Jan |
Cheapest Day Mon |
High Season Jul - Sept |
Low Season Jan - Mar |
Busiest Day Sat |
Least Busy Day Fri |
Best time to book 14 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Coach from £4
Live departures
Rome to Isernia train times
The table below shows live departures for Rome to Isernia trains for today, Thursday 8 October. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
| Regionale 23425 | 17:38 Rome Tiburtina | 2h14 | 19:52 Isernia station | 0 changesdirect | |
| Regionale 5835 · Autobus RM114 | 18:07 Rome Termini | 2h48 | 20:55 Isernia station | 1 change | |
 FRECCIAROSSA 9643+Regionale 23495 | 18:53 Rome Termini | 2h50 | 21:43 Isernia station | 1 change | |
| Regionale 23381 | 20:07 Rome Termini | 2h19 | 22:26 Isernia station | 0 changesdirect | |
| Friday 9 October | |||||
| Regionale 23363 | 6:15 Rome Termini | 2h12 | 8:27 Isernia station | 0 changesdirect | |
| Regionale 23365 | 9:07 Rome Termini | 2h08 | 11:15 Isernia station | 0 changesdirect | |
 Intercity 551+Regionale 5190 | 9:26 Rome Termini | 4h38 | 14:04 Isernia station | 1 change | |
| FRECCIAROSSA 9515+Regionale 5190 | 11:00 Rome Termini | 3h04 | 14:04 Isernia station | 1 change | |
| Regionale 23367 | 13:07 Rome Termini | 2h16 | 15:23 Isernia station | 0 changesdirect | |
| Regionale 23369 | 14:35 Rome Termini | 2h05 | 16:40 Isernia station | 0 changesdirect | |
| Regionale 5893 · Regionale 5196 | 14:53 Rome Termini | 4h27 | 19:20 Isernia station | 1 change | |
| FRECCIAROSSA 9535+Regionale 5196 | 16:05 Rome Termini | 3h15 | 19:20 Isernia station | 1 change | |
| Regionale 12627 · Regionale 5829 · Regionale 5196 | 16:07 Rome Termini | 3h13 | 19:20 Isernia station | 2 changes | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Why should you book Rome to Isernia trains with Omio?
Frecciarossa as well as Intercity, Regionale, Intercity Notte and more offer trains services from Rome to Isernia.
Omio is an official ticket reseller for all your travel options from Rome to Isernia.
Why book with Omio vs Frecciarossa?
- Compare with other providers: On Omio, you can not only buy tickets for Frecciarossa, but also compare tickets for the likes of Intercity, Regionale or Intercity Notte to find the best option for your trip from Rome to Isernia.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Frecciarossa with all available travel options, which are train and bus to ensure you get the best deal for traveling from Rome to Isernia.
Why book with Omio over Raileurope?
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Rome to Isernia.
Train companies: Regionale, Intercity, Intercity Notte, Frecciarossa from Rome to Isernia trainsRegionale, Intercity, Intercity Notte, Frecciarossa trains will get you between Rome and Isernia from £4. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Regionale
About
Regionale is the regional train service of national carrier Trenitalia connecting all of Italy. It is the most convinient way to travel to both big cities and the smallest villages all over the Italian country. The regional trains have different names depending on the region they serve, such as Treno Regionale Veloce (TRV) and Treno Regionale Lento (TRL). Treno Rock and Treno pop are the two new trains part of Trenitalia regionale fleet. Trenitalia Regionale offers a variety of ticket types, including single tickets (economy and standard), return tickets, and season tickets. Onboard facilities include free Wi-Fi, air conditioning, and power sockets. The most popular routes for Regionale are between Rome and Milan, Naples and Florence, and Turin and Venice.
Luggage & cancellation policy
Average Regionale Duration
2h 5m
Cheapest Regionale Price
£12
Regionale frequency
10 a day
Luggage included
Free hand luggage allowance included in ticket price
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Bar service available on some trains with snacks and beverages
Seat reservation
Seat reservation included in ticket price for most services
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle
Quiet zone
Intercity
About
Trenitalia Intercity is a high-speed train service operated by the Italian national railway company, Trenitalia. It operates throughout the country, with services running from early morning to late evening. The Intercity trains come in two types: the Intercity Plus, which is the fastest and most comfortable, and the Intercity, which is slightly slower but still offers a comfortable journey. Onboard facilities include air conditioning, power sockets, Wi-Fi, and a bar service. There are several ticket types available, including Standard, Super Economy, and Business. The most popular routes for Trenitalia Intercity are from Rome to Milan, Naples to Florence, and Turin to Venice.
Luggage & cancellation policy
Average Intercity Duration
3h 29m
Cheapest Intercity Price
£21
Intercity frequency
1 a day
Luggage included
2 pieces of luggage up to 30kg total
Luggage storage
Overhead racks and designated luggage areas at end of carriages
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with hot meals and snacks, trolley service in some trains. But do not count on the presence of a buffet car. So if having access to food and drink on the train is important to you, it’s best to bring your own refreshments onboard.
Seat reservation
Seat reservation included in ticket price for most routes
Toilets
USB plugs
Accessibility
Wheelchair spaces and accessible toilets available
Pets
Small pets in carriers allowed free, larger dogs require paid ticket
Quiet zone
Intercity Notte
About
Intercity Notte is an Italian train service operated by Trenitalia. It runs overnight services between major cities in Italy, making it a great option for travelers looking to save time and money. The Intercity Notte offers two types of trains: the Frecciarossa Notte and the Frecciargento Notte. The Frecciarossa Notte is the fastest train, with speeds of up to 300 km/h, while the Frecciargento Notte is slightly slower but still offers a comfortable journey. Both trains offer a range of onboard facilities, including comfortable seating, air conditioning, and Wi-Fi. Trenitalia offers a range of ticket types, including Standard, Comfort, and Business. Standard tickets are the most affordable, while Comfort and Business tickets offer additional benefits such as priority boarding and access to the lounge. The most popular routes for Intercity Notte are Rome to Milan, Rome to Venice, and Milan to Venice. These routes offer travelers the chance to explore some of Italy's most iconic cities in a convenient and comfortable way.
Luggage & cancellation policy
Average Intercity Notte Duration
3h 42m
Cheapest Intercity Notte Price
£23
Intercity Notte frequency
1 a day
Luggage included
1 handbag and 1 suitcase included in ticket price
Luggage storage
Luggage racks above seats and at carriage ends
Cancellation Policy
Cancellation possible according to ticket type conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full dining service and bar
Seat reservation
Seat reservation included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for disabled passengers
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs free.
Quiet zone
Frecciarossa
About
Step on board a Frecciarossa train and relax as you travel across Italy. Trenitalia’s Frecciarossa high-speed trains make around 200 connections across the country each day and are renowned for their comfort, speed, and reduced environmental impact. Reaching speeds of up to 186 mph (300 km/h), they connect major destinations such as Rome, Florence, Milan, Venice, and Naples quickly and efficiently. When booking your Frecciarossa journey, you can choose between four classes: Standard, Premium, Business, and Executive. While each class offers different levels of comfort, all provide free Wi-Fi access, power outlets, air conditioning, bathrooms, luggage storage, onboard entertainment, and restaurant and bar services. Ticket options include Super Economy, Economy, and Base, making it easy to find the right balance of comfort and price for your trip.
Luggage & cancellation policy
Average Frecciarossa Duration
1h 59m
Cheapest Frecciarossa Price
£31
Frecciarossa frequency
1 a day
Luggage included
1 carry-on bag and 1 suitcase per passenger
Luggage storage
Overhead racks, dedicated luggage areas at carriage ends, under seats
Cancellation Policy
Refund policy depends on ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals, bar service with snacks and beverages, at-seat service in Executive class
Seat reservation
Included in Executive class, optional fee for other classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, service animals free
Quiet zone
Complete guide to Isernia
Things to do in Isernia
Discover the best of Isernia — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Isernia trip today.
- Recommended
Museo Diocesano di Isernia
This museum preserves liturgical objects, sculpture and documents linked to the cathedral and diocesan history in a central historic setting.
Museo Civico della Memoria e della Storia
A small civic museum focused on local memory, archaeology and traditional culture, useful for understanding Isernia beyond its headline sites.
- Must visit
Corso Marcelli
This long historic street follows the spine of the old town, lined with stone buildings, small churches and everyday local life.
- Recommended
Piazza Andrea d'Isernia
The principal square of the historic centre, surrounded by churches and palaces, is the best starting point for exploring old Isernia on foot.
- Recommended
Centro storico di Isernia
The old town area preserves medieval lanes, arches and stone houses, making it ideal for wandering and seeing the city beyond its main monuments.
Lasagna all’Isernina
Fresh pasta sheets layered with rich ragù, tiny meatballs, mozzarella and eggs. A festive Molise bake often served on Sundays and feast days.
- Vegetarian
- Vegan
Zuppa di legumi e cereali del Molise
Hearty country soup of mixed pulses and cereals, often beans, chickpeas and farro. It reflects Molise’s frugal mountain cooking and farmhouse traditions.
Cavatelli al sugo d’agnello
Handmade pasta with a sauce of lamb or mutton, typical of inland Molise’s pastoral culture. It is prized for its robust, rustic flavour.
Osteria dei Sensi
Smart, established dining room serving refined regional cooking with seasonal ingredients and a more polished atmosphere.
Ristorante Da Patrizia
Traditional restaurant in Isernia known for Molise specialities, handmade pasta and grilled meats in a relaxed local setting.
La Strada
Casual pizzeria and restaurant popular for wood-fired pizza, local dishes and an easy-going atmosphere suited to families and groups.
Euro (€)
Moderate for Italy. Accommodation and dining are usually cheaper than Rome or Florence, while local buses and everyday coffee remain fairly affordable for visitors.
Average meal costs
- Budget
- €8-12 for a simple meal or takeaway.
- Mid-range
- €20-35 per person for a restaurant meal.
- Fine dining
- €50+ per person for upscale dining.
- Coffee
- €1.20-2.50 for coffee or cappuccino.
Tipping culture
Service is often included or modest. Round up in cafés and taxis, or leave 5-10% at restaurants for good service; tipping is appreciated, not expected.
Trenitalia
Get the appOfficial public transport app
Prices
- Single ticket
- Unknown
- Day pass
- None
To the city centre
Isernia -> Piazza della Repubblica, Isernia
- Distance
- 1 km
- Travel time
- 15 min
- Isernia railway station is close to the centre, so walking is often the simplest option.
- Check Trenitalia or RFI before travel, as rail replacement buses can operate on lines serving Isernia.
FAQs: Rome to Isernia train
Find answers to the most common questions about traveling from Rome to Isernia by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Isernia, this guide helps you travel smarter and with confidence.
The cost of a train ticket from Rome to Isernia can vary. The cheapest tickets are usually available from £12, while the average price tends to be around £24.
The train journey from Rome to Isernia covers a distance of 149 km and takes approximately 1h 59m. Trains run 10 per day.
The train distance from Rome to Isernia is 149 km.
The first train from Rome to Isernia leaves at 4:50.
The last train from Rome to Isernia departs at 23:56.
Trains from Rome to Isernia run approximately 10 times per day.
Yes, there is a high-speed train service from Rome to Isernia.
Yes, there is a direct train between Rome and Isernia. The service operates 5 times per day, provided by Regionale.
Yes, there is a night train from Rome to Isernia.
The train station in Rome that goes to Isernia is Rome Termini, and it arrives at Isernia station.
Booking trains from Rome to Isernia in advance is advisable, especially during peak travel seasons or for long journeys, to ensure availability and secure better fares.
The train journey from Rome to Isernia offers scenic views, especially as it travels through the picturesque Italian countryside, with rolling hills and charming villages, providing a pleasant visual experience.
Yes, you can take the train from Rome to Isernia.
popular train stations
Important Stations and Airports in Rome and Isernia
Most Rome to Isernia trains use the Roma Termini to Isernia station pair. Use this guide to compare Rome and Isernia train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Departure train stations in Rome
Arrival train stations in Isernia
Which Rome station do trains to Isernia leave from?
Trains from Rome to Isernia leave from Roma Termini. The station is 2 km from Rome city centre at Piazza dei Cinquecento 1, 00185 Rome, Italy.
Roma TerminiPiazza dei Cinquecento 1, 00185 Rome, Italy+39 064745421
City-centre transport
Getting to Roma Termini from Rome city centre
Roma Termini is 1 km from Rome city centre. Public transport options include:
Metro linesA (red), B (blue)
Bus lines5, H, 38, 40 Express, 50 Express, 64, 66, 70, 75, 82, 90 Express, 92, 105, 150F, 223, 310, 590, 714, 910, C2, C3
Tram lines5, 14
Train linesItalo, FR, FA, FB, IC, ICN, EN, CNL, R, Leonardo Express
Roma Termini train station facilities and services
Roma Termini has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Car Rental and Information Desk.
Food and drink
Food options include: Acafe, Moka Café, Roadhouse Grill, McDonald's, Gusto, Chef Express, Coop Minimarket, Mercato Centrale
Wi-Fi and ATMs
Free WiFi in the station. ATMs are there are ATMs in various locations around the station.
Tickets and information
The ticket office is open Mon - Sun: 06:30 - 22:00. Information desks are located near Platform 24.
Luggage and lost property
Luggage storage is provided by KiPoint and located on Platform 24. Open every day from 06:00 to 23:00.
Parking, taxis and toilets
Available at Roma Termini: Parking, Taxis, WC.
Bike and car services
Available at Roma Termini: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at Roma Termini: The Sala Blu, Trenitalia's office of assistance for disabled travelers, is located next to Platform 1.
Shops, hotels and contact
Nearby hotels include Archi di Roma Guest House, Gemma di Roma, The Liberty Boutique Hotel.
Roma TiburtinaPiazzale Stazione Tiburtina, 00162 Roma RM, Italy+39 892021
City-centre transport
Getting to Roma Tiburtina from Rome city centre
Roma Tiburtina is 4 km from Rome city centre. Public transport options include:
Train8914, 9970, 9948, 9946, 9924, 9916, 9912, 9904, 8928, 8924, 8918, 8922, 8908, 8906, 8904, 8900, 8134, 9944, 9966, 9920, 9908, 8916, 8910, 9954, 9940 · 5m · £0.89 · every ~6 min
Bus490, 495 · 24m · £2 · every ~22 min
SubwayMeb · 13m · £2 · every ~15 min
Roma Tiburtina train station facilities and services
Roma Tiburtina has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Car Rental and Information Desk.
Food and drink
Food options include: Rock n’ Coffee Roma, Arabian Kebab, Ingredienti, McDonald’s, Numb's Bakery Café
Wi-Fi and ATMs
Free, limited Wi-Fi available in the station for 15 minutes. ATMs are located on the ground floor level.
Tickets and information
The ticket office is open Mon - Sun: 06:35 - 20:20. Information desks are located inside the main terminal. .
Luggage and lost property
Luggage storage is luggage lockers are located in the station lobby.
Parking, taxis and toilets
Available at Roma Tiburtina: Parking, Taxis, WC.
Bike and car services
Available at Roma Tiburtina: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at Roma Tiburtina: Accessible facilities include elevators and escalators.
Shops, hotels and contact
Nearby hotels include B&B Rome Tiburtina, B&B Alba Domus Roma, Hotel delle Province.
Roma OstiensePiazzale dei Partigiani, 00154 Rome, Italy+39 06 575 5310
City-centre transport
Getting to Roma Ostiense from Rome city centre
Roma Ostiense is 2 km from Rome city centre. Public transport options include:
TrainRe, 4140, 4138, 4136, 4134, 4130, 34474, 34476, 34488, 34482, 34480, 4132, 4128 · 11m · £0.89 · every ~4 min
BusnMB, n716 · 19m · £2 · every ~6 min
nMB, n716 · 22m · £2 · every ~6 min
SubwayMeb, Meb1 · 12m · £2 · every ~29 min
Roma Ostiense train station facilities and services
Roma Ostiense has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk and Luggage Carts.
Food and drink
Food options include: Ramen Bar Akira, Eataly Roma
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Roma Ostiense. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Roma Ostiense. Lost and found is available at the station.
Parking, taxis and toilets
Available at Roma Ostiense: Parking, Taxis, WC.
Bike and car services
Available at Roma Ostiense: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at Roma Ostiense: Elevators, ramps, restrooms.
Shops, hotels and contact
Nearby hotels include Hotel Abitart, Hotel San Anselmo, Hotel Villa San Pio.
Which Isernia station do trains from Rome arrive at?
Trains from Rome to Isernia arrive at Isernia. Isernia is from Isernia city centre.
IserniaPiazza della Repubblica, 86170 Isernia IS, Italy+39 0865 4131
City-centre transport
Getting to Isernia from Isernia city centre
Bus31 · 1m · £3
Isernia train station facilities and services
Isernia has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Information Desk and Luggage Carts.
Food and drink
Food options include: Pasta e Pizza, Ristorante da Adriano
Wi-Fi and ATMs
Free.
Tickets and information
Ticket office support is available at Isernia. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Isernia. Lost and found is available at the station.
Parking, taxis and toilets
Available at Isernia: Parking, Taxis, WC.
Bike and car services
Available at Isernia: Bike Parking.
Accessibility
Accessibility facilities are available at Isernia: Ramps.
Shops, hotels and contact
Nearby hotels include Grand Hotel Europa, Hotel Ristorante Sayonara, Hotel La Tequila.
More options for your journey from Rome to Isernia
Here are some other resources that might have the information you need
Most popular trains to and from Isernia and Rome
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