- Must visit
Museo Nazionale del Paleolitico di Isernia
The National Palaeolithic Museum presents the famous prehistoric finds from La Pineta with clear displays on early human life in Molise.
Cheapest price on 19 Sept
£8
Average ticket price on 19 Sept
£9
Fastest journey on 19 Sept
1 h 59 m
Average journey duration on 19 Sept
2 h 9 m
Trains on 19 Sept
5
Distance
85 km
The best way to find a cheap train ticket from Naples to Isernia is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Naples to Isernia will cost around £9 if you buy it on the day, but you can find cheap train tickets today for only £8.
On Sat 19 Sept, we found 5 trains from Naples to Isernia, including 4 direct services.
These direct trains cover the 85 km distance in an average of 2 h 9 m but if you time it right, some trains will get you there in just 1 h 59 m .
The slowest trains will take 2 h 16 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Regionale 23495
Regionale 5192
Regionale 5196
Regionale 5190
Regionale 21139 · Regionale 94884
Regionale 5192
Regionale 23495
Regionale 5190
Regionale 5196
Regionale 21139 · Regionale 94884Omio recommends booking the train as it is the most popular option from Naples to Isernia among Omio's users. If you are prioritising price, take the train, with an average ticket price of £11 For those with little time, consider booking a train, which has an average total journey time of 2h 34m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.0 - 0.1kg. Average ticket prices depend on the travel mode: a train costs an average of £11, while a coach costs an average of £13.
Distance: 85 km
Most popular Train | Coach |
|---|---|
£11 Average Price Cheapest | £13 Average Price |
2h 34m Average total duration Fastest 2h 4m Onboard + 30m Additional time* | 2h 34m Average total duration 2h 4m Onboard + 30m Additional time* |
0.0 - 0.1kg CO2 emissions Lowest | 0.1 - 0.2kg CO2 emissions |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Naples to Isernia:
A train is £2 less than a coach for this route with tickets for a coach from Naples to Isernia costing on average £13.
Other travel options to Isernia take longer:
Coach takes on average 2h 4m.
The table below shows live departures for Naples to Isernia trains for today, Friday 18 September. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
Regionale 23495 | 19:38 Naples Centrale | 2h05 | 21:43 Isernia station | 0 changesdirect | |
| Saturday 19 September | |||||
Regionale 21139 · Regionale 94884 | 7:04 Naples Centrale | 2h16 | 9:20 Isernia station | 1 change | |
Regionale 5190 | 11:54 Naples Centrale | 2h10 | 14:04 Isernia station | 0 changesdirect | |
Regionale 5192 | 13:54 Naples Centrale | 1h59 | 15:53 Isernia station | 0 changesdirect | |
Regionale 5196 | 17:06 Naples Centrale | 2h14 | 19:20 Isernia station | 0 changesdirect | |
Find all the dates and times for this journey
Compare train and coach prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Naples to Isernia run on average 8 times per day, taking around 2h 5m. Cheap train tickets for this journey start at £8 but you can travel from only £8 by coach.
There are 2 trains per day. The earliest train runs at 03:55, the last at 20:35. The fastest train covers the 85 km distance in 1h 59m.
Distance 85 km |
Average train duration 2h 5m |
Cheapest ticket price £8 |
Trains per day 8 |
Direct trains 2 |
Fastest train 1h 59m |
First train 3:55 |
Last train 20:35 |
Cheapest Month Aug |
Cheapest Day Sat |
High Season Jul - Sept |
Low Season Apr - Jun |
Busiest Day Tue |
Least Busy Day Thu |
Best time to book 1 day |
Discover the best of Isernia — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Isernia trip today.
The National Palaeolithic Museum presents the famous prehistoric finds from La Pineta with clear displays on early human life in Molise.
This museum preserves liturgical objects, sculpture and documents linked to the cathedral and diocesan history in a central historic setting.
A small civic museum focused on local memory, archaeology and traditional culture, useful for understanding Isernia beyond its headline sites.
This long historic street follows the spine of the old town, lined with stone buildings, small churches and everyday local life.
The principal square of the historic centre, surrounded by churches and palaces, is the best starting point for exploring old Isernia on foot.
The old town area preserves medieval lanes, arches and stone houses, making it ideal for wandering and seeing the city beyond its main monuments.
Fresh pasta sheets layered with rich ragù, tiny meatballs, mozzarella and eggs. A festive Molise bake often served on Sundays and feast days.
Hearty country soup of mixed pulses and cereals, often beans, chickpeas and farro. It reflects Molise’s frugal mountain cooking and farmhouse traditions.
Handmade pasta with a sauce of lamb or mutton, typical of inland Molise’s pastoral culture. It is prized for its robust, rustic flavour.
Smart, established dining room serving refined regional cooking with seasonal ingredients and a more polished atmosphere.
Traditional restaurant in Isernia known for Molise specialities, handmade pasta and grilled meats in a relaxed local setting.
Casual pizzeria and restaurant popular for wood-fired pizza, local dishes and an easy-going atmosphere suited to families and groups.
Moderate for Italy. Accommodation and dining are usually cheaper than Rome or Florence, while local buses and everyday coffee remain fairly affordable for visitors.
Service is often included or modest. Round up in cafés and taxis, or leave 5-10% at restaurants for good service; tipping is appreciated, not expected.
Official public transport app
Isernia -> Piazza della Repubblica, Isernia
Find answers to the most common questions about traveling from Naples to Isernia by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Isernia, this guide helps you travel smarter and with confidence.

Most Naples to Isernia trains use the Napoli Centrale to Isernia station pair. Use this guide to compare Naples and Isernia train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Napoli Centrale is 2 km from Naples city centre. Public transport options include:
Napoli Centrale has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Car Rental and Information Desk.
Food options include: Tentazioni Cafe, Burger King, VyTA Boulangerie, Time Cafè, Caffè Toraldo, Chalet Ciro, Cibiamo, Chef Express, Eccellenze Della Costiera, 100 Montaditos, & more
Free WiFi throughout the station. ATMs are located at various points in the station.
The ticket office is open Mon - Sun: 05:50 - 21:10. Information desks are located on the ground floor in the main concourse.
Luggage storage is kiPoint luggage storage is located close to Platform 2, open daily from 06:00 to 23:00. .
Available at Napoli Centrale: Parking, Taxis, WC.
Available at Napoli Centrale: Car Rental.
Accessibility facilities are available at Napoli Centrale: The station is fully accessible. The Sala Blu office provides services and assists customers with disabilities. .
Nearby hotels include Grand Hotel Europa, Starhotels Terminus, B&B Hotel Napoli.
Isernia has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Information Desk and Luggage Carts.
Food options include: Pasta e Pizza, Ristorante da Adriano
Free.
Ticket office support is available at Isernia. Information desks are located in the main hall.
Luggage storage is available at Isernia. Lost and found is available at the station.
Available at Isernia: Parking, Taxis, WC.
Available at Isernia: Bike Parking.
Accessibility facilities are available at Isernia: Ramps.
Nearby hotels include Grand Hotel Europa, Hotel Ristorante Sayonara, Hotel La Tequila.
Here are some other resources that might have the information you need