Rome to Isernia bus with FlixBus

Fri 18 Sept
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FlixBus
BlaBlaCar
Marino Autolinee
ATM Azienda di Trasporti Molisana S.p.A.
National Express
2,000+ travel companies
FlixBus
BlaBlaCar
Marino Autolinee
ATM Azienda di Trasporti Molisana S.p.A.
National Express
2,000+ travel companies
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The cheapest and fastest coaches from Rome to Isernia

Showing times, prices and bookable tickets for 18 Sept

Cheapest price on 18 Sept

£11

Average ticket price on 18 Sept

£11

Fastest journey on 18 Sept

2 h 25 m

Average journey duration on 18 Sept

2 h 28 m

Buses on 18 Sept

2

Distance

149 km

Cheap tickets

The best way to find a cheap coach ticket from Rome to Isernia is to book your journey as far in advance as possible and to avoid travelling at rush hour.

The average ticket from Rome to Isernia will cost around £11 if you buy it on the day, but you can find cheap coach tickets today for only £11.

Fast coaches

On Fri 18 Sept, we found 2 buses from Rome to Isernia, including 2 direct services.

These direct buses cover the 149 km distance in an average of 2 h 28 m but if you time it right, some buses will get you there in just 2 h 25 m .

The slowest buses will take 2 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • Marino Autolinee058
    16:302h30
    Roma, Autostazione Tiburtina
    19:00Isernia, Piazza della Repubblica (F. Martino bus station)
    £111One-way
    0 changes
  • FlixBusFlixBus
    14:502h25
    Roma, Autostazione Tiburtina
    17:15Isernia, Piazza della Repubblica (F. Martino bus station)
    £121One-way
    0 changes

Travel Information

Compare train and coach for Rome to Isernia

Omio recommends booking the train as it is the most popular option from Rome to Isernia among Omio's users. If you are prioritising price, take the coach, with an average ticket price of £11 For those with little time, consider booking a coach, which has an average total journey time of 2h 43m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.0 - 0.1kg. Average ticket prices depend on the travel mode: a coach costs an average of £11, while a train costs an average of £14.

Distance: 149 km

Compare bus with

Coach
Most popular
Train
Driving

£11

Average Price

Cheapest

£14

Average Price

£37

Average Price

(fuel + tolls)

2h 43m

Average total duration

Fastest

2h 13m

Onboard

+

30m

Additional time*

3h 39m

Average total duration

3h 9m

Onboard

+

30m

Additional time*

2h 12m

Average total duration

(door-to-door)

0.1 - 0.4kg

CO2 emissions

0.0 - 0.1kg

CO2 emissions

Lowest

-

CO2 emissions

FlixBus

Most popular bus company

Regionale

Most popular train company

Your own car or car rental

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from Rome to Isernia is a coach with an average price of £11.

This is compared to other travel options from Rome to Isernia:

A coach is £3 less than a train for this route with tickets for a train from Rome to Isernia costing on average £14.

The fastest way to travel from Rome to Isernia is by coach with an average journey time of 2h 13m.

Other travel options to Isernia take longer:

Train takes on average 3h 9m.

It's helpful to compare your options as there are 2 ways to travel between Rome and Isernia including taking a train and coach.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around £11 compared to roughly £37 in fuel and tolls — a saving of about £26. The journey takes 2h 13m versus 2h 12m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Direct services are operated by FlixBus, BlaBlaCar, Marino Autolinee, ATM Azienda di Trasporti Molisana S.p.A..

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Live departures

Rome to Isernia bus times

The table below shows live departures for Rome to Isernia coaches for tomorrow, Friday 18 September. You can also manually refresh the results below to see updated coach journeys.

Last updated at
ProviderDepartsDurationArrivesChanges
Tickets
FlixBusFlixBus14:50 Roma, Autostazione Tiburtina
2h25
17:15 Isernia, Piazza della Repubblica (F. Martino bus station)0 changesdirect
Marino Autolinee05816:30 Roma, Autostazione Tiburtina
2h30
19:00 Isernia, Piazza della Repubblica (F. Martino bus station)0 changesdirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Rome to Isernia by train or coach

Compare train and coach prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
18 Sept
Sat
19 Sept
Sun
20 Sept
Mon
21 Sept
Tue
22 Sept
Wed
23 Sept
Thu
24 Sept

Why should you book Rome to Isernia coaches with Omio?

FlixBus as well as Marino Autolinee or ATM Azienda di Trasporti Molisana S.p.A. offer coaches services from Rome to Isernia.
Omio is an official ticket reseller for all your travel options from Rome to Isernia.

Why book with Omio vs FlixBus?

  • Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Marino Autolinee or ATM Azienda di Trasporti Molisana S.p.A. to find the best option for your trip from Rome to Isernia.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Rome to Isernia.

Why book with Omio over Wanderu, Trainline or Checkmybus?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of Marino Autolinee or ATM Azienda di Trasporti Molisana S.p.A. to find the best option for your trip from Rome to Isernia.
  • Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Rome to Isernia.

Journey information

Overview: Bus from Rome to Isernia

ItalyItaly
ItalyItaly
Icon of bus

Buses from Rome to Isernia run on average 10 times per day, taking around 2h 13m. Cheap bus tickets for this journey start at £5 if you book in advance.

There are 6 coaches per day. The earliest coach runs at 02:45, the last at 23:56. The fastest coach covers the 149 km distance in 2h 10m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
149 km
Average bus duration
2h 13m
Cheapest ticket price
£5
Buses per day
10
Direct buses
6
Fastest bus
2h 10m
First bus
2:45
Last bus
23:56
Cheapest Month
Mar
Cheapest Day
Sat
High Season
Jul - Sept
Low Season
Jan - Mar
Busiest Day
Sat
Least Busy Day
Fri
Best time to book
28 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus, BlaBlaCar, Marino Autolinee, ATM Azienda di Trasporti Molisana S.p.A. from Rome to IserniaYou can travel by bus between Rome to Isernia with FlixBus, BlaBlaCar, Marino Autolinee, ATM Azienda di Trasporti Molisana S.p.A. for as low as £5. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
2h 10m
Cheapest FlixBus Price
£10
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Marino Autolinee

About
MarinoBus is an Italian bus company with more than 200 destinations and 6,000 connections across Italy and Europe. Originally focused on Basilicata and Apulia, its network has expanded to cover the rest of Italy as well as Switzerland, France, Germany, and Luxembourg. All MarinoBus coaches are equipped with spacious reclining seats, air conditioning, onboard restrooms, WiFi, minibars, and color TVs. For your next trip, you can book the standard ticket, which includes one piece of hand luggage and up to two checked bags per passenger
Luggage & cancellation policy
Average Marino Autolinee Duration
2h 30m
Cheapest Marino Autolinee Price
£5
Luggage included
One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
10€ per additional bag up to 20 kg.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.

BlaBlaCar

About
BlaBlaCar is a French online marketplace for carpooling, connecting drivers with empty seats and passengers traveling to the same destination to share costs. Founded in 2006, it operates in Europe and Latin America, boasting 26 million active members. The platform also includes BlaBlaCar Bus, an intercity bus service. BlaBlaCar's name comes from its rating system for drivers' chattiness: \Bla\" for quiet, \"BlaBla\" for talkative, and \"BlaBlaBla\" for very chatty. The company aims to be the leading marketplace for shared travel, offering affordable and sustainable solutions by combining carpooling with bus journeys."
Luggage & cancellation policy
BlaBlaCar frequency
5 a day

ATM Azienda di Trasporti Molisana S.p.A.

Luggage & cancellation policy
Average ATM Azienda di Trasporti Molisana S.p.A. Duration
2h 10m
Cheapest ATM Azienda di Trasporti Molisana S.p.A. Price
£9
ATM Azienda di Trasporti Molisana S.p.A. frequency
2 a day

Bus providers: FlixBus, BlaBlaCar, Marino Autolinee, ATM Azienda di Trasporti Molisana S.p.A. from Rome to IserniaYou can travel by bus between Rome to Isernia with FlixBus, BlaBlaCar, Marino Autolinee, ATM Azienda di Trasporti Molisana S.p.A. for as low as £5. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
2h 10m
Cheapest FlixBus Price
£10
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Marino Autolinee

About
MarinoBus is an Italian bus company with more than 200 destinations and 6,000 connections across Italy and Europe. Originally focused on Basilicata and Apulia, its network has expanded to cover the rest of Italy as well as Switzerland, France, Germany, and Luxembourg. All MarinoBus coaches are equipped with spacious reclining seats, air conditioning, onboard restrooms, WiFi, minibars, and color TVs. For your next trip, you can book the standard ticket, which includes one piece of hand luggage and up to two checked bags per passenger
Luggage & cancellation policy
Average Marino Autolinee Duration
2h 30m
Cheapest Marino Autolinee Price
£5
Luggage included
One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
10€ per additional bag up to 20 kg.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.

What's included in each class

Compare Marino Autolinee classes and the amenities included in each one.

Standard
  • Power plugs
  • Wide seats
  • Extra legroom

BlaBlaCar

About
BlaBlaCar is a French online marketplace for carpooling, connecting drivers with empty seats and passengers traveling to the same destination to share costs. Founded in 2006, it operates in Europe and Latin America, boasting 26 million active members. The platform also includes BlaBlaCar Bus, an intercity bus service. BlaBlaCar's name comes from its rating system for drivers' chattiness: \Bla\" for quiet, \"BlaBla\" for talkative, and \"BlaBlaBla\" for very chatty. The company aims to be the leading marketplace for shared travel, offering affordable and sustainable solutions by combining carpooling with bus journeys."
Luggage & cancellation policy
BlaBlaCar frequency
5 a day

ATM Azienda di Trasporti Molisana S.p.A.

Luggage & cancellation policy
Average ATM Azienda di Trasporti Molisana S.p.A. Duration
2h 10m
Cheapest ATM Azienda di Trasporti Molisana S.p.A. Price
£9
ATM Azienda di Trasporti Molisana S.p.A. frequency
2 a day

Complete guide to Isernia

Things to do in Isernia

Discover the best of Isernia — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Isernia trip today.

  • Must visit

Museo Nazionale del Paleolitico di Isernia

The National Palaeolithic Museum presents the famous prehistoric finds from La Pineta with clear displays on early human life in Molise.

  • Recommended

Museo Diocesano di Isernia

This museum preserves liturgical objects, sculpture and documents linked to the cathedral and diocesan history in a central historic setting.

Museo Civico della Memoria e della Storia

A small civic museum focused on local memory, archaeology and traditional culture, useful for understanding Isernia beyond its headline sites.

Euro (€)

Moderate for Italy. Accommodation and dining are usually cheaper than Rome or Florence, while local buses and everyday coffee remain fairly affordable for visitors.

Average meal costs

Budget
€8-12 for a simple meal or takeaway.
Mid-range
€20-35 per person for a restaurant meal.
Fine dining
€50+ per person for upscale dining.
Coffee
€1.20-2.50 for coffee or cappuccino.

Tipping culture

Service is often included or modest. Round up in cafés and taxis, or leave 5-10% at restaurants for good service; tipping is appreciated, not expected.

FAQs: Rome to Isernia coach

Find answers to the most common questions about traveling from Rome to Isernia by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Isernia, this guide helps you travel smarter and with confidence.

FAQs
Cheap coach tickets from Rome to Isernia can start from as little as £5 when you book in advance. The average coach ticket price for Rome to Isernia is £11; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by coach from Rome to Isernia is 2h 10m to travel the 149 km long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest coach from Rome to Isernia leaves at 2:45. Plan your trip with the Journey Planner from Omio.
The latest coach from Rome to Isernia leaves at 23:56.
Yes, there are 6 direct coaches a day from Rome to Isernia with FlixBus, BlaBlaCar, Marino Autolinee, ATM Azienda di Trasporti Molisana S.p.A.. Schedules can vary on holidays or weekends with fewer direct coaches.
When taking a coach from Rome to Isernia, you can count on FlixBus, BlaBlaCar, Marino Autolinee, ATM Azienda di Trasporti Molisana S.p.A. for the best way to get you to Isernia. You can also check all possible coach companies who offer a service between Rome and Isernia and compare the amenities they offer before buying a coach ticket.
When departing from Rome , you have various coach station options to start your route from including Roma, Autostazione Tiburtina, Amsterdam, Piarcoplein (Amsterdam Sloterdijk), Amsterdam, Centraal Station, Amsterdam, Station Bijlmer Arena, Ciampino, Aeroporto Internazionale di Roma–Ciampino "G. B. Pastine", Schiphol, Airport Terminal 1 . When arriving in Isernia , you can end your route in coach stations like Isernia, Piazza della Repubblica (F. Martino bus station), Venafro, Via Colonia Giulia, Bojano, Piazza Roma.Passengers board the coach most frequently from Roma, Autostazione Tiburtina, which is located around 4 km away from the city centre, and they get off the coach at Isernia, Piazza della Repubblica (F. Martino bus station), located 0 away from the city centre.
A trip to Isernia from Rome is worth doing but not as a day trip with a journey time of 2h 10m each way. Check with Omio app the best way to travel.
The cheapest month for a coach from Rome to Isernia is March.
It's helpful to compare your options as there are 2 ways to travel between Rome and Isernia including taking a train and coach.
Yes, the following accessibility options are available when taking the coach from Rome to Isernia:
  • Marino Autolinee
    • Assistance
    • Priority seating
    • Accessible restrooms.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the coach from Rome to Isernia for coach company FlixBus, Marino Autolinee.
Whether you can cancel your coach ticket from Rome to Isernia depends on the coach companies:
  • Marino Autolinee
    • You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the coach with coach company FlixBus, Marino Autolinee.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the coach from Rome to Isernia.
Yes, the following luggage options are included when booking a coach ticket from Rome to Isernia:
  • Marino Autolinee
    • One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a coach ticket from Rome to Isernia:
  • Marino Autolinee
    • 10€ per additional bag up to 20 kg.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the coach from Rome to Isernia. The following conditions apply:
  • Marino Autolinee
    • Small pets allowed in carriers
    • larger pets must be leashed and muzzled.
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the coach from Rome to Isernia with the following coach company: FlixBus, Marino Autolinee
Yes, there are USB plugs on board the coach from Rome to Isernia with the following coach company: FlixBus, Marino Autolinee.
Yes, there is Wifi on board the coach from Rome to Isernia with the following coach company: FlixBus, Marino Autolinee.

popular bus stations

Important Stations and Airports in Rome and Isernia

Most Rome to Isernia buses use the Roma, Autostazione Tiburtina to Isernia, Piazza della Repubblica (Autostazione F. Martino) station pair. Use this guide to compare Rome and Isernia bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Rome
Arrival bus stations in Isernia

Which Rome station do buses to Isernia leave from?

Buses from Rome to Isernia leave from Roma, Autostazione Tiburtina. The station is 4 km from Rome city centre at Largo Guido Mazzoni, snc, 00162 Roma RM, Italy.
Roma, Autostazione TiburtinaLargo Guido Mazzoni, snc, 00162 Roma RM, ItalyWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Roma, Autostazione Tiburtina from Rome city centre

Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:

Bus490, 495 · 16m · £2 · every ~22 min
SubwayMeb · 7m · £2 · every ~15 min

Roma, Autostazione Tiburtina bus station facilities and services

Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.

Food and drink

Food options include: Cafes and vending machines available.

Wi-Fi and ATMs

Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.

Tickets and information

Ticket office support is available at Roma, Autostazione Tiburtina.

Parking, taxis and toilets

Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.

More options for your journey from Rome to Isernia

Here are some other resources that might have the information you need

HomeCoachesBuses in ItalyRome to Isernia bus

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