The cheapest and fastest coaches from Rome to Isernia
Cheapest price
£7
Average price
£10
Fastest journey
1 h 20 m
Average duration
1 h 30 m
Buses per day
5
Distance
149 km
The best way to find a cheap coach ticket from Rome to Isernia is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Rome to Isernia will cost around £10 if you buy it on the day, but you can find cheap coach tickets today for only £7.
Of the 5 buses that leave Rome for Isernia every day 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct buses cover the 149 km distance in an average of 1 h 30 m but if you time it right, some buses will get you there in just 1 h 20 m .
The slowest buses will take 1 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Travel Information
Compare coach and train for Rome to Isernia
Omio recommends booking the train as it is the most popular option from Rome to Isernia among Omio's users. If you are prioritising price take the train with prices starting from £12. For those with little time consider booking a coach which can get you there in 2h 14m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.0 - 0.1kg. The ticket price range depends on the travel mode: a train costs an average of £12, and a coach costs an average of £10.
Distance: 149 km
Compare bus with
| Coach | Most popular Train |
|---|---|
£18 Average Price | £17 Average Price Cheapest |
2h 44m Average total duration Fastest 2h 14m Onboard + 30m Additional time* | 3h 59m Average total duration 3h 29m Onboard + 30m Additional time* |
0.1 - 0.4kg CO2 emissions | 0.0 - 0.1kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Rome to Isernia bus times
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 04:10 Roma, Autostazione Tiburtina | 6h14 | 10:24 Isernia, Piazza della Repubblica (F. Martino bus station) | 1 change | |
| Thursday 6 November | |||||
![]() | 03:50 Rome | 5h34 | 09:24 Isernia | 0 changesdirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Isernia by coach or train
05 Nov
06 Nov
07 Nov
08 Nov
09 Nov
10 Nov
11 Nov
12 Nov
13 Nov
14 Nov
15 Nov
16 Nov
17 Nov
18 Nov
Journey information
Overview: Bus from Rome to Isernia
Distance 149 km |
Average bus duration 2h 14m |
Cheapest ticket price £10 |
Buses per day 7 |
Direct buses 6 |
Fastest bus 2h 15m |
First bus 00:15 |
Last bus 23:58 |
Bus providers: FlixBus, BlaBlaCar, ATM Azienda di Trasporti Molisana S.p.A. from Rome to IserniaYou can travel by bus between Rome to Isernia with FlixBus, BlaBlaCar, ATM Azienda di Trasporti Molisana S.p.A. for as low as £10. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar
ATM Azienda di Trasporti Molisana S.p.A.
FAQs: Rome to Isernia coach

When departing from Rome, you have various coach station options to start your journey from including Rome, Termini, Rome, Termini (G) and Rome, Roma Ostiense. When arriving in Isernia, you can end your journey in coach stations like Isernia, Piazzale Santo Spirito (Piazzale Homo Aeserniensis) and Isernia, Piazza della Repubblica (F. Martino bus station).
Passengers board the coach most frequently from Rome, Termini, which is located around 2.2 miles (3.5 km) away from the city centre, and they get off the coach at Isernia, Piazzale Santo Spirito (Piazzale Homo Aeserniensis), located 0.7 miles (1.2 km) away from the city centre.
popular bus stations
Important Stations and Airports in Rome and Isernia
Most popular bus connections from Rome
More options for your journey from Rome to Isernia
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