1st Class
- Power plugs
- Wide seats
- Food available
- Extra legroom
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest trains from Isernia to Rome
Showing times, prices and bookable tickets for 18 Sept
Cheapest price on 18 Sept
£13
Average ticket price on 18 Sept
£22
Fastest journey on 18 Sept
2 h 9 m
Average journey duration on 18 Sept
2 h 19 m
Trains on 18 Sept
14
Distance
149 km
Cheap tickets
The best way to find a cheap train ticket from Isernia to Rome is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Isernia to Rome will cost around £22 if you buy it on the day, but you can find cheap train tickets today for only £13.
Fast trains
On Fri 18 Sept, we found 14 trains from Isernia to Rome, including 6 direct services.
These direct trains cover the 149 km distance in an average of 2 h 19 m but if you time it right, some trains will get you there in just 2 h 9 m .
The slowest trains will take 2 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Autobus RM113 · Regionale 125984:503h01Isernia station7:51Rome Termini£131One-way1 change- Regionale 5181 · Regionale 58427:083h05Isernia station10:13Rome Termini£131One-way1 change
- Regionale 233478:382h09Isernia station10:47Rome Termini£131One-way0 changes
- Regionale 2335115:032h24Isernia station17:27Rome Termini£131One-way0 changes
- Regionale 2336120:352h19Isernia station22:54Rome Termini£131One-way0 changes
- Regionale 233478:382h09Isernia station10:47Rome Termini£131One-way0 changes
- Regionale 233416:352h18Isernia station8:53Rome Termini£131One-way0 changes
- Regionale 2336120:352h19Isernia station22:54Rome Termini£131One-way0 changes
- Regionale 2335115:032h24Isernia station17:27Rome Termini£131One-way0 changes
- Regionale 2335918:002h25Isernia station20:25Rome Termini£131One-way0 changes
Travel Information
Compare train and coach for Isernia to Rome
Omio recommends booking the train as it is the most popular option from Isernia to Rome among Omio's users. If you are prioritising price, take the coach, with an average ticket price of £10 For those with little time, consider booking a coach, which has an average total journey time of 2h 50m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.0 - 0.1kg. Average ticket prices depend on the travel mode: a coach costs an average of £10, while a train costs an average of £17.
Distance: 149 km
Compare train with
Most popular Train | Coach | Driving |
|---|---|---|
£17 Average Price | £10 Average Price Cheapest | £37 Average Price (fuel + tolls) |
3h 18m Average total duration 2h 48m Onboard + 30m Additional time* | 2h 50m Average total duration Fastest 2h 20m Onboard + 30m Additional time* | 2h 26m Average total duration (door-to-door) |
0.0 - 0.1kg CO2 emissions Lowest | 0.1 - 0.4kg CO2 emissions | - CO2 emissions |
Most popular train company |  Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Isernia to Rome is a coach with an average price of £10.
This is compared to other travel options from Isernia to Rome:
A coach is £7 less than a train for this route with tickets for a train from Isernia to Rome costing on average £17.
The fastest way to travel from Isernia to Rome is by coach with an average journey time of 2h 20m.
Other travel options to Rome take longer:
Train takes on average 2h 48m.
It's helpful to compare your options as there are 2 ways to travel between Isernia and Rome including taking a train and coach.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.
Tickets start at around £17 compared to roughly £37 in fuel and tolls — a saving of about £20. The journey takes 2h 48m versus 2h 26m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Direct services run with Regionale.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Isernia to Rome train times
The table below shows live departures for Isernia to Rome trains for today, Thursday 17 September. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
| Regionale 23349 | 13:28 Isernia station | 2h26 | 15:54 Rome Tiburtina | 0 changesdirect | |
Regionale 5189+ FRECCIAROSSA 8314 | 14:06 Isernia station | 2h59 | 17:05 Rome Termini | 1 change | |
| Regionale 23351 | 15:03 Isernia station | 2h24 | 17:27 Rome Termini | 0 changesdirect | |
| Autobus CB101 · Regionale 5813+FRECCIAROSSA 9592 | 15:20 Isernia station | 4h35 | 19:55 Rome Termini | 2 changes | |
| Autobus CB101 · Regionale 5826 · Regionale 12636 | 15:20 Isernia station | 5h00 | 20:20 Rome Termini | 2 changes | |
| Regionale 5191 · Metropolitano 21461+FRECCIAROSSA 8868 | 16:45 Isernia station | 3h31 | 20:16 Rome Termini | 2 changes | |
| Regionale 23359 | 18:00 Isernia station | 2h25 | 20:25 Rome Termini | 0 changesdirect | |
Regionale 5199+ Intercity 704 | 19:01 Isernia station | 3h28 | 22:29 Rome Termini | 1 change | |
| Regionale 23361 | 20:35 Isernia station | 2h19 | 22:54 Rome Termini | 0 changesdirect | |
| Friday 18 September | |||||
| Autobus RM113 · Regionale 12598 | 4:50 Isernia station | 3h01 | 7:51 Rome Termini | 1 change | |
| Regionale 23341 | 6:35 Isernia station | 2h18 | 8:53 Rome Termini | 0 changesdirect | |
| Regionale 5181 · Regionale 5842 | 7:08 Isernia station | 3h05 | 10:13 Rome Termini | 1 change | |
| Regionale 5181+FRECCIAROSSA 9310 | 7:08 Isernia station | 3h02 | 10:10 Rome Termini | 1 change | |
| Regionale 23347 | 8:38 Isernia station | 2h09 | 10:47 Rome Termini | 0 changesdirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Isernia to Rome by train or coach
Compare train and coach prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Fri
18 Sept
18 Sept
Sat
19 Sept
19 Sept
Sun
20 Sept
20 Sept
Mon
21 Sept
21 Sept
Tue
22 Sept
22 Sept
Wed
23 Sept
23 Sept
Thu
24 Sept
24 Sept
Journey information
Overview: Train from Isernia to Rome
ItalyItaly
Trains from Isernia to Rome run on average 9 times per day, taking around 2h 48m. Cheap train tickets for this journey start at £12 but you can travel from only £4 by coach.
There are 2 trains per day. The earliest train runs at 04:50, the last at 23:56. The fastest train covers the 149 km distance in 2h 7m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Coach from £4
Distance 149 km |
Average train duration 2h 48m |
Cheapest ticket price £12 |
Trains per day 9 |
Direct trains 2 |
Fastest train 2h 7m |
First train 4:50 |
Last train 23:56 |
Cheapest Month Aug |
Cheapest Day Wed |
High Season Jul - Sept |
Low Season Jan - Mar |
Busiest Day Sat |
Least Busy Day Wed |
Best time to book 14 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Coach from £4
Train companies: Regionale, Intercity from Isernia to Rome trainsRegionale, Intercity trains will get you between Isernia and Rome from £4. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Regionale
About
Regionale is the regional train service of national carrier Trenitalia connecting all of Italy. It is the most convinient way to travel to both big cities and the smallest villages all over the Italian country. The regional trains have different names depending on the region they serve, such as Treno Regionale Veloce (TRV) and Treno Regionale Lento (TRL). Treno Rock and Treno pop are the two new trains part of Trenitalia regionale fleet. Trenitalia Regionale offers a variety of ticket types, including single tickets (economy and standard), return tickets, and season tickets. Onboard facilities include free Wi-Fi, air conditioning, and power sockets. The most popular routes for Regionale are between Rome and Milan, Naples and Florence, and Turin and Venice.
Luggage & cancellation policy
Average Regionale Duration
2h 7m
Cheapest Regionale Price
£12
Regionale frequency
5 a day
Luggage included
Free hand luggage allowance included in ticket price
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Bar service available on some trains with snacks and beverages
Seat reservation
Seat reservation included in ticket price for most services
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle
Quiet zone
What's included in each class
Compare Regionale classes and the amenities included in each one.
2nd Class
- Power plugs
- Food available
Intercity
About
Trenitalia Intercity is a high-speed train service operated by the Italian national railway company, Trenitalia. It operates throughout the country, with services running from early morning to late evening. The Intercity trains come in two types: the Intercity Plus, which is the fastest and most comfortable, and the Intercity, which is slightly slower but still offers a comfortable journey. Onboard facilities include air conditioning, power sockets, Wi-Fi, and a bar service. There are several ticket types available, including Standard, Super Economy, and Business. The most popular routes for Trenitalia Intercity are from Rome to Milan, Naples to Florence, and Turin to Venice.
Luggage & cancellation policy
Average Intercity Duration
3h 24m
Cheapest Intercity Price
£23
Luggage included
2 pieces of luggage up to 30kg total
Luggage storage
Overhead racks and designated luggage areas at end of carriages
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with hot meals and snacks, trolley service in some trains. But do not count on the presence of a buffet car. So if having access to food and drink on the train is important to you, it’s best to bring your own refreshments onboard.
Seat reservation
Seat reservation included in ticket price for most routes
Toilets
USB plugs
Accessibility
Wheelchair spaces and accessible toilets available
Pets
Small pets in carriers allowed free, larger dogs require paid ticket
Quiet zone
What's included in each class
Compare Intercity classes and the amenities included in each one.
1st Class
- Power plugs
- Wide seats
- Food available
- Extra legroom
- Pets (under 10kg)
2nd Class
- Power plugs
- Food available
- Pets (under 10kg)
Complete guide to Rome
Things to do in Rome
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
- Must visit
Vatican Museums
World-renowned Vatican collections with Raphael Rooms and the Sistine Chapel, essential for art and Church history.
- Must visit
Capitoline Museums
Superb Capitoline collections on Michelangelo's square, showcasing ancient sculpture, bronzes, and Rome's civic history.
- Must visit
Galleria Borghese
Outstanding gallery in a villa setting, celebrated for Bernini sculptures and masterpieces by Caravaggio and Raphael.
- Must visit
Piazza Navona
Baroque square with fountains and lively street life, ideal for people-watching and a classic Rome atmosphere.
- Must visit
Spanish Steps
Famous staircase linking Piazza di Spagna to Trinità dei Monti, beloved for city scenes and elegant surroundings.
- Must visit
Trastevere
Bohemian quarter of lanes, piazzas, and nightlife, popular for evening strolls, local character, and riverside charm.
Carbonara
Roman pasta with guanciale, egg yolk, Pecorino Romano and black pepper. A city icon prized for its rich sauce and no cream tradition.
Amatriciana
Pasta in a sharp, savoury sauce of guanciale, tomato and Pecorino Romano. A classic Roman favourite with roots in local trattoria cooking.
- Vegetarian
Cacio e Pepe
Simple Roman pasta made with Pecorino Romano and black pepper. It shows the city’s love of bold flavour from few ingredients.
Aroma
Michelin-starred restaurant by the Colosseum serving refined Roman cuisine in an elegant setting. Best for a fine-dining splurge.
Da Enzo al 29
Historic Trastevere trattoria known for classic Roman pasta and warm old-school rooms. A dependable choice for traditional local dishes.
Felice a Testaccio
Long-running Testaccio restaurant specialising in Roman quinto quarto and pasta. Informal, authentic and popular with locals and visitors.
Euro (€)
Moderate for a major Western European capital. Hotels in central areas are pricey, but dining and public transport are often cheaper than in Paris or London.
Average meal costs
- Budget
- €8-12 for fast food or street food.
- Mid-range
- €20-35 per person for a meal.
- Fine dining
- €60+ per person for upscale restaurants.
- Coffee
- €1.20-2.50 for coffee or cappuccino.
Tipping culture
Service is often included or covered by a coperto. Rounding up or leaving 5-10% is appreciated in restaurants. In cafés, small change is enough; taxis are usually rounded up.
ATAC Roma
Get the appOfficial public transport app
Prices
- Single ticket
- €1.50
- Day pass
- €8.50
To the city centre
Roma Termini -> Piazza Venezia, Rome
- Distance
- 2 km
- Travel time
- 15 min
- Tap & Go contactless payment works on buses, trams and metro gates; the same card or device must be used for fare capping.
- A BIT ticket is valid for 100 min, but on the metro it covers one journey only, even if you change lines inside the system.
FAQs: Isernia to Rome train
Find answers to the most common questions about traveling from Isernia to Rome by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.
The cost of a train ticket from Isernia to Rome can vary. The cheapest tickets are usually available from £12, while the average price tends to be around £17.
The train journey from Isernia to Rome covers a distance of 149 km and takes approximately 2h 7m. Trains run 9 per day.
The train distance from Isernia to Rome is 149 km.
The first train from Isernia to Rome leaves at 4:50.
The last train from Isernia to Rome departs at 23:56.
Trains from Isernia to Rome run approximately 9 times per day.
Currently, there is no high-speed train service from Isernia to Rome.
Yes, there is a direct train between Isernia and Rome. The service operates 2 times per day, provided by Regionale.
To get from Isernia to Rome, you can choose from several travel options including train and coach.
There is no night train service from Isernia to Rome.
The train station in Isernia that goes to Rome is Isernia station, and it arrives at Rome Termini.
The cheapest way to get from Isernia to Rome is by coach, costing approximately £4.
Booking trains from Isernia to Rome in advance is advisable, especially during peak travel seasons or for long journeys, to ensure availability and secure better fares.
The train journey from Isernia to Rome offers scenic views of the Italian countryside, including rolling hills and picturesque small towns, providing a pleasant visual experience.
A day trip from Isernia to Rome is not feasible as the journey takes 2h 7m. However, there are 8 trains available per day. The distance is 149 km.
In Rome, you can explore Trastevere, a charming neighbourhood with narrow streets and vibrant nightlife, and take a stroll through Villa Borghese, a beautiful park with museums and gardens. Enjoy a gelato at Piazza Navona, a lively square with fountains and street artists. Visit the Spanish Steps for people-watching and a great view, and discover the ancient Catacombs with guided tours. Must-see sights include the Colosseum, Vatican Museums, Roman Forum, Pantheon, and Trevi Fountain.
Three to four days in Rome allows you to experience its key attractions, including the Colosseum, Vatican City, and the Pantheon, while enjoying the city's vibrant culture and cuisine.
Yes, you can take the train from Isernia to Rome.
popular train stations
Important Stations and Airports in Isernia and Rome
Most Isernia to Rome trains use the Isernia to Roma Termini station pair, with some services arriving at Roma Tiburtina. Use this guide to compare Isernia and Rome train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Departure train stations in Isernia
Arrival train stations in Rome
Which Isernia station do trains to Rome leave from?
Trains from Isernia to Rome leave from Isernia. The station is from Isernia city centre at Piazza della Repubblica, 86170 Isernia IS, Italy.
IserniaPiazza della Repubblica, 86170 Isernia IS, Italy+39 0865 4131
City-centre transport
Getting to Isernia from Isernia city centre
Bus31 · 1m · £3
Isernia train station facilities and services
Isernia has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Information Desk and Luggage Carts.
Food and drink
Food options include: Pasta e Pizza, Ristorante da Adriano
Wi-Fi and ATMs
Free.
Tickets and information
Ticket office support is available at Isernia. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Isernia. Lost and found is available at the station.
Parking, taxis and toilets
Available at Isernia: Parking, Taxis, WC.
Bike and car services
Available at Isernia: Bike Parking.
Accessibility
Accessibility facilities are available at Isernia: Ramps.
Shops, hotels and contact
Nearby hotels include Grand Hotel Europa, Hotel Ristorante Sayonara, Hotel La Tequila.
Which Rome station do trains from Isernia arrive at?
Trains from Isernia to Rome most often arrive at Roma Termini. Some services arrive at Roma Tiburtina, so check your ticket before travel to confirm your Rome arrival station.
Roma TerminiPiazza dei Cinquecento 1, 00185 Rome, Italy+39 064745421
City-centre transport
Getting to Roma Termini from Rome city centre
Roma Termini is 1 km from Rome city centre. Public transport options include:
Metro linesA (red), B (blue)
Bus lines5, H, 38, 40 Express, 50 Express, 64, 66, 70, 75, 82, 90 Express, 92, 105, 150F, 223, 310, 590, 714, 910, C2, C3
Tram lines5, 14
Train linesItalo, FR, FA, FB, IC, ICN, EN, CNL, R, Leonardo Express
Roma Termini train station facilities and services
Roma Termini has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Car Rental and Information Desk.
Food and drink
Food options include: Acafe, Moka Café, Roadhouse Grill, McDonald's, Gusto, Chef Express, Coop Minimarket, Mercato Centrale
Wi-Fi and ATMs
Free WiFi in the station. ATMs are there are ATMs in various locations around the station.
Tickets and information
The ticket office is open Mon - Sun: 06:30 - 22:00. Information desks are located near Platform 24.
Luggage and lost property
Luggage storage is provided by KiPoint and located on Platform 24. Open every day from 06:00 to 23:00.
Parking, taxis and toilets
Available at Roma Termini: Parking, Taxis, WC.
Bike and car services
Available at Roma Termini: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at Roma Termini: The Sala Blu, Trenitalia's office of assistance for disabled travelers, is located next to Platform 1.
Shops, hotels and contact
Nearby hotels include Archi di Roma Guest House, Gemma di Roma, The Liberty Boutique Hotel.
Roma TiburtinaPiazzale Stazione Tiburtina, 00162 Roma RM, Italy+39 892021
City-centre transport
Getting to Roma Tiburtina from Rome city centre
Roma Tiburtina is 4 km from Rome city centre. Public transport options include:
Train8914, 9970, 9948, 9946, 9924, 9916, 9912, 9904, 8928, 8924, 8918, 8922, 8908, 8906, 8904, 8900, 8134, 9944, 9966, 9920, 9908, 8916, 8910, 9954, 9940 · 5m · £0.90 · every ~6 min
Bus490, 495 · 24m · £2 · every ~22 min
SubwayMeb · 13m · £2 · every ~15 min
Roma Tiburtina train station facilities and services
Roma Tiburtina has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Car Rental and Information Desk.
Food and drink
Food options include: Rock n’ Coffee Roma, Arabian Kebab, Ingredienti, McDonald’s, Numb's Bakery Café
Wi-Fi and ATMs
Free, limited Wi-Fi available in the station for 15 minutes. ATMs are located on the ground floor level.
Tickets and information
The ticket office is open Mon - Sun: 06:35 - 20:20. Information desks are located inside the main terminal. .
Luggage and lost property
Luggage storage is luggage lockers are located in the station lobby.
Parking, taxis and toilets
Available at Roma Tiburtina: Parking, Taxis, WC.
Bike and car services
Available at Roma Tiburtina: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at Roma Tiburtina: Accessible facilities include elevators and escalators.
Shops, hotels and contact
Nearby hotels include B&B Rome Tiburtina, B&B Alba Domus Roma, Hotel delle Province.
Roma San PietroPiazza della Stazione di San Pietro, 00165 Rome, Italy
City-centre transport
Getting to Roma San Pietro from Rome city centre
Roma San Pietro is 2 km from Rome city centre. Public transport options include:
TrainRe, 4140, 4138, 4136, 4134, 4130, 34488, 34482, 34480, 34476, 34474, 4128, 4132 · 20m · £2 · every ~5 min
Busn46, n98 · 27m · £2 · every ~4 min
64 · 32m · £2 · every ~19 min
Roma San Pietro train station facilities and services
Roma San Pietro has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Information Desk and Luggage Carts.
Food and drink
Food options include: Ristorante La Vittoria, Osteria dei Pontefici
Wi-Fi and ATMs
Free.
Tickets and information
Ticket office support is available at Roma San Pietro. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Roma San Pietro. Lost and found is available at the station.
Parking, taxis and toilets
Available at Roma San Pietro: Parking, Taxis, WC.
Bike and car services
Available at Roma San Pietro: Bike Parking.
Accessibility
Accessibility facilities are available at Roma San Pietro: Elevators, ramps, restrooms.
Shops, hotels and contact
Nearby hotels include Starhotels Michelangelo Rome, Hotel San Pietro, Hotel Paolo II.
Most popular train connections from Isernia
More options for your journey from Isernia to Rome
Here are some other resources that might have the information you need
Most popular trains to and from Rome and Isernia
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
