The cheapest and fastest trains from Prague to Palermo
Cheapest price
£225
Average price
£225
Fastest journey
1 d 11 h 35 m
Average duration
1 d 11 h 35 m
Trains per day
1
Distance
1334 km
The best way to find a cheap train ticket from Prague to Palermo is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Prague to Palermo will cost around £225 if you buy it on the day, but you can find cheap train tickets today for only £225.
To travel from Prague to Palermo you need to make at least 3 changes.


Travel Information
Compare train, coach and flight for Prague to Palermo
Omio recommends booking the flight as it is the most popular option from Prague to Palermo among Omio's users. If you are prioritising price take the coach with prices starting from £83. For those with little time consider booking a flight which can get you there in 3h 4m. The ticket price range depends on the travel mode: a coach costs an average of £83, and a train costs an average of £250.
Distance: 1334 km
Compare train with
| Train | Most popular Flight | Coach |
|---|---|---|
£265 Average Price | £216 Average Price | £126 Average Price Cheapest |
44h 19m Average total duration 43h 49m Onboard + 30m Additional time* | 6h 4m Average total duration Fastest 3h 4m Onboard + 3h 0m Additional time* | 36h 0m Average total duration 35h 30m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Prague to Palermo train times
The table below shows live departures for Prague to Palermo trains for tomorrow, Friday 20 March. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
![]() | 07:35 Prague | 35h35 | 19:10 Palermo | 3 changes | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Prague to Palermo by train, coach or flight
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
21 Mar
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01 Apr
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Journey information
Overview: Train from Prague to Palermo
Trains from Prague to Palermo run on average 1 times per day, taking around 43h 49m. Cheap train tickets for this journey start at £250 but you can travel from only £83 by coach.
The earliest train runs at 06:20, the last at 14:20. The fastest train covers the 1334 km distance in 36h 42m.
Distance 1334 km |
Average train duration 43h 49m |
Cheapest ticket price £250 |
Trains per day 1 |
Fastest train 36h 42m |
First train 06:20 |
Last train 14:20 |
Train companies: ÖBB | Euro City (EC) from Prague to Palermo trainsÖBB | Euro City (EC) trains will get you between Prague and Palermo from £83. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
ÖBB | Euro City (EC)
FAQs: Prague to Palermo train
Find answers to the most common questions about traveling from Prague to Palermo by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

Most popular train connections from Prague
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