EC 335 · NJ 44814:2119h38Prague hlavní nádraží9:59Brussels-Midi£221One-way1 change
RJ 384 · IC 2048 · ICE 2587 · ICE 146:3111h04Prague hlavní nádraží17:35Brussels-Midi£901One-way3 changes
RJ 384 · IC 2048 · ICE 2587 · ICE 146:3111h04Prague hlavní nádraží17:35Brussels-Midi£901One-way3 changes
rj 176 · ICE 554 · ICE 31812:3111h23Prague hlavní nádraží23:54Brussels-Midi£951One-way2 changes
rj 384 · IC 2048 · ICE 2587 · ICE 146:3111h04Prague hlavní nádraží17:35Brussels-Midi£951One-way3 changes
RJ 384 · IC 2048 · ICE 2587 · ICE 146:3111h04Prague hlavní nádraží17:35Brussels-Midi£901One-way3 changes
RJ 384 · IC 2048 · ICE 2587 · ICE 146:3111h04Prague hlavní nádraží17:35Brussels-Midi£901One-way3 changes
RJ 178 · IC 2440 · ICE 2589 · ICE 128:3111h04Prague hlavní nádraží19:35Brussels-Midi£1501One-way3 changes
RJ 382 · IC 2442 · ICE 2591 · ICE 1010:3111h04Prague hlavní nádraží21:35Brussels-Midi£1501One-way3 changes
rj 384 · IC 2048 · ICE 2587 · ICE 146:3111h04Prague hlavní nádraží17:35Brussels-Midi£951One-way3 changes
Travel Information
Compare train, coach and flight for Prague to Brussels
Omio recommends booking the flight as it is the most popular option from Prague to Brussels among Omio's users. If you are prioritising price take the coach with prices starting from £40. For those with little time consider booking a flight which can get you there in 3h 21m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a coach costs an average of £40, and a flight costs an average of £22.
Distance: 717 km
Compare train with
| Train | Most popular Flight | Coach |
|---|---|---|
£101 Average Price | £127 Average Price | £69 Average Price Cheapest |
12h 20m Average total duration 11h 50m Onboard + 30m Additional time* | 6h 21m Average total duration Fastest 3h 21m Onboard + 3h 0m Additional time* | 15h 24m Average total duration 14h 54m Onboard + 30m Additional time* |
0.2 - 0.6kg CO2 emissions Lowest | 2.2 - 4.3kg CO2 emissions | 0.7 - 1.8kg CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Prague to Brussels train times
The table below shows live departures for Prague to Brussels trains for today, Wednesday 29 July. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
NJ 456 · ICE 1654 · ICE 314 | Delayed 1:14 3:14Prague hlavní nádraží | 12h21 | 14:30 14:30Brussels-Midi | 2 changes | |
EX 360 · 3564 · ICE 628 · ICE 122 | Delayed 7:35 Prague hlavní nádraží | 12h00 | 18:26 18:26Brussels-Midi | 4 changes | |
RJ 178 · IC 2440 · ICE 2589 · ICE 12 | Delayed 8:31 Prague hlavní nádraží | 11h04 | 18:26 18:26Brussels-Midi | 3 changes | |
rj 178 · IC 2440 · ICE 2589 · ICE 12 | Delayed 8:31 Prague hlavní nádraží | 11h04 | 18:26 18:26Brussels-Midi | 3 changes | |
RJ 178 · IC 2440 · ICE 2589 · ICE 12 | Delayed 8:31 Prague hlavní nádraží | 11h04 | 18:26 18:26Brussels-Midi | 3 changes | |
rj 178 · ICE 1558 · ICE 10 | Delayed 8:31 Prague hlavní nádraží | 13h04 | 20:24 20:24Brussels-Midi | 2 changes | |
RJ 178 · ICE 558 · ICE 10 | Delayed 8:31 Prague hlavní nádraží | 13h04 | 20:24 20:24Brussels-Midi | 2 changes | |
EX 358 · 3568 · ICE 624 · ICE 224 | Delayed 9:35 Prague hlavní nádraží | 12h00 | 20:24 20:24Brussels-Midi | 4 changes | |
rj 382 · IC 2442 · ICE 2591 · ICE 10 | Delayed 10:31 Prague hlavní nádraží | 11h04 | 20:24 20:24Brussels-Midi | 3 changes | |
RJ 382 · IC 2442 · ICE 2591 · ICE 10 | Delayed 10:31 Prague hlavní nádraží | 11h04 | 20:24 20:24Brussels-Midi | 3 changes | |
RJ 176 · IC 2444 · ICE 2593 · ICE 318 | Delayed 12:31 Prague hlavní nádraží | 11h23 | 22:45 22:45Brussels-Midi | 3 changes | |
rj 176 · ICE 544 · ICE 318 | Delayed 12:31 Prague hlavní nádraží | 11h23 | 22:45 22:45Brussels-Midi | 2 changes | |
R 688 · Os 28009 · S1 · ICE 1554 | 12:47 Prague hlavní nádraží | 17h00 | 5:47 Brussels-Midi | 7 changes | |
EC 458 · ICE 699 · ICE 18 | On time 18:31 Prague hlavní nádraží | 15h04 | 9:35 Brussels-Midi | 2 changes | |
R 676 · Os 28015 · S1 · 16538 | On time 18:47 Prague hlavní nádraží | 16h48 | 11:35 Brussels-Midi | 6 changes | |
RJ 478 · ICE 956 · ICE 16 | On time 0:33 Prague hlavní nádraží | 13h02 | 13:35 Brussels-Midi | 2 changes | |
RJ 384 · IC 2048 · ICE 2587 · ICE 14 | On time 6:31 Prague hlavní nádraží | 11h04 | 17:35 Brussels-Midi | 3 changes | |
RJ 384 · IC 2048 · ICE 2587 · ICE 14 | On time 6:31 Prague hlavní nádraží | 11h04 | 17:35 Brussels-Midi | 3 changes | |
rj 384 · IC 2048 · ICE 2587 · ICE 14 | On time 6:31 Prague hlavní nádraží | 11h04 | 17:35 Brussels-Midi | 3 changes | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Prague to Brussels by train, coach or flight
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
29 Jul
30 Jul
31 Jul
01 Aug
02 Aug
03 Aug
04 Aug
05 Aug
06 Aug
07 Aug
08 Aug
09 Aug
10 Aug
11 Aug
12 Aug
13 Aug
14 Aug
15 Aug
16 Aug
17 Aug
18 Aug
Why should you book Prague to Brussels trains with Omio?
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of České dráhy, Alibus, ÖBB | Euro City (EC) or České dráhy (ČD) to find the best option for your trip from Prague to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Prague to Brussels.
Why book with Omio over Trainline, Wanderu or Raileurope?
- Compare with other providers: On Omio, you can also compare tickets for the likes of České dráhy, Alibus, ÖBB | Euro City (EC) or České dráhy (ČD) to find the best option for your trip from Prague to Brussels.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Prague to Brussels.
How far in advance should I book train tickets from Prague to Brussels?
Journey information
Overview: Train from Prague to Brussels
Trains from Prague to Brussels run on average 7 times per day, taking around 11h 50m. Cheap train tickets for this journey start at £13 if you book in advance.
The earliest train runs at 00:10, the last at 23:55. The fastest train covers the 717 km distance in 11h 4m.
Distance 717 km |
Average train duration 11h 50m |
Cheapest ticket price £13 |
Trains per day 7 |
Fastest train 11h 4m |
First train 0:10 |
Last train 23:55 |
Cheapest Month Mar |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Sun |
Least Busy Day Sat |
Best time to book 77 days |
Train companies: Deutsche Bahn, České dráhy, Alibus, ÖBB | Euro City (EC), České dráhy (ČD), ÖBB | Railjet from Prague to Brussels trainsDeutsche Bahn, České dráhy, Alibus, ÖBB | Euro City (EC), České dráhy (ČD), ÖBB | Railjet trains will get you between Prague and Brussels from £13. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Alibus
ÖBB | Euro City (EC)
ÖBB | Railjet
České dráhy
České dráhy (ČD)
FAQs: Prague to Brussels train
Find answers to the most common questions about traveling from Prague to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Prague and Brussels
Most Prague to Brussels trains use the Praha hlavní nádraží to Bruxelles-Midi station pair, with some services arriving at Bruxelles-Central. Use this guide to compare Prague and Brussels train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Which Prague station do trains to Brussels leave from?
Getting to Praha hlavní nádraží from Prague city centre
Praha hlavní nádraží is 1 km from Prague city centre. Public transport options include:
Praha hlavní nádraží train station facilities and services
Praha hlavní nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk and Luggage Carts.
Food and drink
Food options include: Restaurant Fantova Kavárna, Sushi Time
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Praha hlavní nádraží. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Praha hlavní nádraží. Lost and found is available at the station.
Parking, taxis and toilets
Available at Praha hlavní nádraží: Parking, Taxis, WC.
Bike and car services
Available at Praha hlavní nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Praha hlavní nádraží: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Hotel Esplanade Prague, Falkensteiner Hotel Maria Prag, Hotel City Central.
Getting to Praha Masarykovo Nádraží from Prague city centre
Praha Masarykovo Nádraží train station facilities and services
Praha Masarykovo Nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk and Luggage Carts.
Food and drink
Food options include: Restaurant Kotleta, Café Imperial
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Praha Masarykovo Nádraží. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Praha Masarykovo Nádraží. Lost and found is available at the station.
Parking, taxis and toilets
Available at Praha Masarykovo Nádraží: Parking, Taxis, WC.
Bike and car services
Available at Praha Masarykovo Nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Praha Masarykovo Nádraží: Ramps.
Shops, hotels and contact
Nearby hotels include Hotel Kings Court, Grand Hotel Bohemia, Hotel Paris Prague.
Getting to Praha-Holesovice from Prague city centre
Praha-Holesovice is 2 km from Prague city centre. Public transport options include:
Praha-Holesovice train station facilities and services
Praha-Holesovice has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk and Luggage Carts.
Food and drink
Food options include: Restaurant Na Kovárně, Cross Club
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Praha-Holesovice. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Praha-Holesovice. Lost and found is available at the station.
Parking, taxis and toilets
Available at Praha-Holesovice: Parking, Taxis, WC.
Bike and car services
Available at Praha-Holesovice: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Praha-Holesovice: Ramps, restrooms.
Shops, hotels and contact
Nearby hotels include Mama Shelter Prague, Plaza Alta Hotel, Hotel Belvedere.
Which Brussels station do trains from Prague arrive at?
Getting to Bruxelles-Midi from Brussels city centre
Bruxelles-Midi train station facilities and services
Bruxelles-Midi has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental and Information Desk.
Food and drink
Food options include: Pullman Hotel Bar, Quick Gare du Midi, Subway, EXKi Zuid, Starbucks, Häagen-Dazs, Sbarro, The Coffee Club, The Belgian Chocolate House, PAUL, & many more
Wi-Fi and ATMs
Wi-Fi is available for a fee. ATMs are available at Bruxelles-Midi.
Tickets and information
Ticket office support is available at Bruxelles-Midi. Information desks are located in the main concourse and next to the international platforms.
Luggage and lost property
Luggage storage is baggage storage facility is located across from the Thalys business lounge.
Parking, taxis and toilets
Available at Bruxelles-Midi: Parking, Taxis, WC.
Bike and car services
Available at Bruxelles-Midi: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Bruxelles-Midi: Station has a wide range of facilities for passengers with reduced mobility: elevators and escalators to all platforms, wheelchair lifts and mobile ramps, disabled toilet and parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
Shops, hotels and contact
Nearby hotels include Les Lofts De Styliste, Park Inn by Radisson Brussels Midi, Pullman Brussels Centre Midi.
Getting to Bruxelles-Central from Brussels city centre
Bruxelles-Central train station facilities and services
Bruxelles-Central has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental and Information Desk.
Food and drink
Food options include: Starbucks, Brasserie 28 Brewery, Panos, Delitraiteur Eat & Go
Wi-Fi and ATMs
Free Wi-Fi available in Starbucks. ATMs are aTM machine is downstairs from the main entrance on the right side.
Tickets and information
The ticket office is open Mon - Sun: 06:15 - 22:00. Information desks are travel Center / information desk is located on the left side from the main entrance.
Luggage and lost property
Luggage storage is luggage lockers are located on Level 0 near Platforms 1 and 2.
Parking, taxis and toilets
Available at Bruxelles-Central: Parking, Taxis, WC.
Bike and car services
Available at Bruxelles-Central: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Bruxelles-Central: Station has a wide range of facilities for passengers with limited mobility: elevators and escalators to platforms, wheelchair lifts and mobile ramps, barrier-free toilets and accessible parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
Shops, hotels and contact
Nearby hotels include Hilton Brussels Grand Palace, Hotel NH Brussels Carrefour de l'Europe, Hôtel The Moon.
Getting to Bruxelles-Congres from Brussels city centre
Bruxelles-Congres train station facilities and services
Bruxelles-Congres has practical services for this route, including Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Bike Parking and Bike Rental.
Food and drink
Food and drink options are available at Bruxelles-Congres.
Wi-Fi and ATMs
ATMs are available at Bruxelles-Congres.
Parking, taxis and toilets
Available at Bruxelles-Congres: Parking, Taxis, WC.
Bike and car services
Available at Bruxelles-Congres: Bike Parking, Bike Rental.
Accessibility
Accessibility facilities are available at Bruxelles-Congres.
Most popular train connections from Prague
More options for your journey from Prague to Brussels
Here are some other resources that might have the information you need


