The cheapest and fastest trains from Prague to Brussels
Cheapest price
£143
Average price
£196
Fastest journey
12 h
Average duration
13 h 38 m
Trains per day
4
Distance
717 km
The best way to find a cheap train ticket from Prague to Brussels is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Prague to Brussels will cost around £196 if you buy it on the day, but you can find cheap train tickets today for only £143.
To travel from Prague to Brussels you need to make at least 2 changes.
EX 354 · 3433 · ICE 526 · 26836
EX 356 · 3572 · ICE 620 · ICE 318
EX 358 · ICE 1224 · ICE 10
EC 358 · ICE 1224 · ICE 10
EX 356 · 3572 · ICE 620 · ICE 318
EX 358 · ICE 1224 · ICE 10
EC 358 · ICE 1224 · ICE 10
EX 354 · 3433 · ICE 526 · 26836Travel Information
Compare train, coach and flight for Prague to Brussels
Omio recommends booking the flight as it is the most popular option from Prague to Brussels among Omio's users. If you are prioritising price take the coach with prices starting from £36. For those with little time consider booking a flight which can get you there in 3h 21m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a coach costs an average of £36, and a flight costs an average of £19.
Distance: 717 km
Compare train with
| Train | Most popular Flight | Coach |
|---|---|---|
£89 Average Price | £98 Average Price | £61 Average Price Cheapest |
12h 17m Average total duration 11h 47m Onboard + 30m Additional time* | 6h 21m Average total duration Fastest 3h 21m Onboard + 3h 0m Additional time* | 15h 10m Average total duration 14h 40m Onboard + 30m Additional time* |
0.2 - 0.6kg CO2 emissions Lowest | 2.2 - 4.3kg CO2 emissions | 0.7 - 1.8kg CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Prague to Brussels train times
The table below shows live departures for Prague to Brussels trains for tomorrow, Sunday 15 March. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
EX 358 · ICE 1224 · ICE 10 | On time 08:35 Prague hlavní nádraží | 12h00 | 20:35 Brussels-Midi | 2 changes | |
EC 358 · ICE 1224 · ICE 10 | On time 08:35 Prague hlavní nádraží | 12h00 | 20:35 Brussels-Midi | 2 changes | |
EX 356 · 3572 · ICE 620 · ICE 318 | On time 10:35 Prague hlavní nádraží | 12h00 | 22:35 Brussels-Midi | 3 changes | |
EX 354 · 3433 · ICE 526 · 26836 | On time 12:35 Prague hlavní nádraží | 18h30 | 07:05 Brussels-Midi | 7 changes | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Prague to Brussels by train, coach or flight
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
15 Mar
16 Mar
17 Mar
18 Mar
19 Mar
20 Mar
21 Mar
22 Mar
23 Mar
24 Mar
25 Mar
26 Mar
27 Mar
28 Mar
29 Mar
30 Mar
31 Mar
01 Apr
02 Apr
03 Apr
04 Apr
Why should you book Prague to Brussels trains with Omio?
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of České dráhy, European Sleeper or European Sleeper to find the best option for your trip from Prague to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Prague to Brussels.
Why book with Omio over Trainline, Wanderu or Raileurope?
- Compare with other providers: On Omio, you can also compare tickets for the likes of České dráhy, European Sleeper or European Sleeper to find the best option for your trip from Prague to Brussels.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Prague to Brussels.
How far in advance should I book train tickets from Prague to Brussels?
Journey information
Overview: Train from Prague to Brussels
Trains from Prague to Brussels run on average 7 times per day, taking around 11h 47m. Cheap train tickets for this journey start at £12 if you book in advance.
The earliest train runs at 00:10, the last at 23:55. The fastest train covers the 717 km distance in 10h 55m.
Distance 717 km |
Average train duration 11h 47m |
Cheapest ticket price £12 |
Trains per day 7 |
Fastest train 10h 55m |
First train 00:10 |
Last train 23:55 |
Train companies: Deutsche Bahn, České dráhy, European Sleeper from Prague to Brussels trainsDeutsche Bahn, České dráhy, European Sleeper trains will get you between Prague and Brussels from £12. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
European Sleeper
České dráhy
FAQs: Prague to Brussels train
Find answers to the most common questions about traveling from Prague to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Prague and Brussels
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, 24 hours a day. Access via Wilsonova Street.
- Restaurant Fantova Kavárna
- Sushi Time
- Outside the main entrance.
- Elevators, ramps.
- CZK 10
- Hotel Esplanade Prague
- Falkensteiner Hotel Maria Prag
- Hotel City Central
- Cost CZK 100
- Located in the main hall
- Located in the main hall
- Avis
- Europcar
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-7 for trains to Germany, Austria, Slovakia, and regional destinations
- Hall 2: Metro connections
- Metro: Line C
- Tram: Lines 5, 9, 26
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available nearby with several public parking options.
- Restaurant Kotleta
- Café Imperial
- Outside the main entrance.
- Ramps.
- CZK 10
- Hotel Kings Court
- Grand Hotel Bohemia
- Hotel Paris Prague
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for regional and suburban trains
- Metro: Line B
- Tram: Lines 3, 5, 14, 24
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available 24/7 with access from Partyzánská street.
- Restaurant Na Kovárně
- Cross Club
- Outside the main entrance.
- Ramps, restrooms.
- CZK 10
- Mama Shelter Prague
- Plaza Alta Hotel
- Hotel Belvedere
- Located in the main hall
- Avis
- Budget
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for trains to Germany, Austria, and regional destinations
- Hall 2: ticket office and waiting area
- Metro: Line C
- Tram: Lines 6, 12, 17
- Bus: Several lines available
- Mon - Sun: 05:45 - 21:30
- Wi-Fi is available for a fee.
- Baggage storage facility is located across from the Thalys business lounge.
- Pullman Hotel Bar
- Quick Gare du Midi
- Subway
- EXKi Zuid
- Starbucks
- Häagen-Dazs
- Sbarro
- The Coffee Club
- The Belgian Chocolate House
- PAUL
- & many more
- Station has a wide range of facilities for passengers with reduced mobility: elevators and escalators to all platforms, wheelchair lifts and mobile ramps, disabled toilet and parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
- Les Lofts De Styliste
- Park Inn by Radisson Brussels Midi
- Pullman Brussels Centre Midi
- Located in the main concourse and next to the international platforms.
- Mon - Sun: 06:15 - 22:00
- Free Wi-Fi available in Starbucks.
- Luggage lockers are located on Level 0 near Platforms 1 and 2.
- Starbucks
- Brasserie 28 Brewery
- Panos
- Delitraiteur Eat & Go
- Station has a wide range of facilities for passengers with limited mobility: elevators and escalators to platforms, wheelchair lifts and mobile ramps, barrier-free toilets and accessible parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
- Hilton Brussels Grand Palace
- Hotel NH Brussels Carrefour de l'Europe
- Hôtel The Moon
- Mon - Sun: 06:15 - 22:00
- Travel Center / information desk is located on the left side from the main entrance.
- Metro lines: 1, 5
- Train lines: IC, Intercity Direct 9200, RER (S1, S2, S3, S6, S8, S10)
Most popular train connections from Prague
More options for your journey from Prague to Brussels
Here are some other resources that might have the information you need


