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The cheapest and fastest trains from Prague to Brussels
Showing times and prices for 15 Dec
Cheapest price
£99
Average price
£128
Fastest journey
10 h 55 m
Average duration
10 h 58 m
Trains per day
15
Distance
717 km
Cheap tickets
The best way to find a cheap train ticket from Prague to Brussels is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Prague to Brussels will cost around £128 if you buy it on the day, but you can find cheap train tickets today for only £99.
Fast trains
To travel from Prague to Brussels you need to make at least 2 changes.
rj 382 · ICE 556 · ICE 1010:3110h55
Prague hlavní nádraží21:26Brussels-North
£991One-way
2 changes
rj 176 · ICE 554 · ICE 31812:3110h55
Prague hlavní nádraží23:26Brussels-North
£991One-way
2 changes
rj 178 · ICE 558 · ICE 1208:3110h55
Prague hlavní nádraží19:26Brussels-North
£991One-way
2 changes
rj 178 · ICE 558 · ICE 12 · R 399008:3111h03
Prague hlavní nádraží19:34Brussels-Central
£1241One-way
3 changes
rj 382 · ICE 556 · ICE 10 · R 199310:3111h44
Prague hlavní nádraží22:15Brussels Congress
£1241One-way
3 changes
rj 382 · ICE 556 · ICE 1010:3110h55
Prague hlavní nádraží21:26Brussels-North
£991One-way
2 changes
rj 176 · ICE 554 · ICE 31812:3110h55
Prague hlavní nádraží23:26Brussels-North
£991One-way
2 changes
rj 178 · ICE 558 · ICE 1208:3110h55
Prague hlavní nádraží19:26Brussels-North
£991One-way
2 changes
rj 178 · ICE 558 · ICE 12 · R 399008:3111h03
Prague hlavní nádraží19:34Brussels-Central
£1241One-way
3 changes
rj 382 · ICE 556 · ICE 10 · R 399210:3111h03
Prague hlavní nádraží21:34Brussels-Central
£1241One-way
3 changes
Travel Information
Compare train, coach and flight for Prague to Brussels
Omio recommends booking the flight as it is the most popular option from Prague to Brussels among Omio's users. If you are prioritising price take the coach with prices starting from £25. For those with little time consider booking a flight which can get you there in 2h 27m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a coach costs an average of £25, and a flight costs an average of £32.
Distance: 717 km
Compare train with
| Train | Most popular Flight | Coach |
|---|---|---|
£148 Average Price | £177 Average Price | £60 Average Price Cheapest |
13h 42m Average total duration 13h 12m Onboard + 30m Additional time* | 5h 27m Average total duration Fastest 2h 27m Onboard + 3h 0m Additional time* | 14h 9m Average total duration 13h 39m Onboard + 30m Additional time* |
0.2 - 0.6kg CO2 emissions Lowest | 2.2 - 4.3kg CO2 emissions | 0.7 - 1.8kg CO2 emissions |
 Most popular train company |  Most popular airline |  Most popular bus company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Prague to Brussels train times
The table below shows live departures for Prague to Brussels trains for today, Sunday 14 December. You can also manually refresh the results below to see updated train journeys.
Last updated at 15:06
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
 452 | 17:00 Prague hlavní nádraží | 15h27 | 08:27 Brussels-Midi | 0 changesdirect | |
| EC 458 · ICE 699 · ICE 18 | 17:31 Prague hlavní nádraží | 14h55 | 08:26 Brussels-North | 2 changes | |
| EC 458 · ICE 699 · ICE 18 · R 1780 | 17:31 Prague hlavní nádraží | 15h18 | 08:49 Brussels Congress | 3 changes | |
| EC 458 · ICE 699 · ICE 18 · R 3980 | 17:31 Prague hlavní nádraží | 15h03 | 08:34 Brussels-Central | 3 changes | |
| Monday 15 December | |||||
| rj 178 · ICE 558 · ICE 12 · R 3990 | 07:31 Prague hlavní nádraží | 11h03 | 18:34 Brussels-Central | 3 changes | |
| RJ 178 · ICE 558 · ICE 12 | On time 07:31 Prague hlavní nádraží | 11h04 | 18:35 Brussels-Midi | 2 changes | |
| rj 178 · ICE 558 · ICE 12 | 07:31 Prague hlavní nádraží | 10h55 | 18:26 Brussels-North | 2 changes | |
| rj 178 · ICE 558 · ICE 12 · R 1790 | 07:31 Prague hlavní nádraží | 11h18 | 18:49 Brussels Congress | 3 changes | |
| rj 178 · ICE 558 · ICE 12 · R 3990 | 07:31 Prague hlavní nádraží | 11h13 | 18:44 Brussels Congress | 4 changes | |
| RJ 382 · ICE 556 · ICE 10 | On time 09:31 Prague hlavní nádraží | 11h04 | 20:35 Brussels-Midi | 2 changes | |
| rj 382 · ICE 556 · ICE 10 · R 1993 | 09:31 Prague hlavní nádraží | 11h44 | 21:15 Brussels Congress | 3 changes | |
| rj 382 · ICE 556 · ICE 10 · R 3992 | 09:31 Prague hlavní nádraží | 11h03 | 20:34 Brussels-Central | 3 changes | |
| rj 382 · ICE 556 · ICE 10 | 09:31 Prague hlavní nádraží | 10h55 | 20:26 Brussels-North | 2 changes | |
| rj 382 · ICE 556 · ICE 10 · R 3992 | 09:31 Prague hlavní nádraží | 11h13 | 20:44 Brussels Congress | 4 changes | |
| RJ 176 · ICE 554 · ICE 318 | On time 11:31 Prague hlavní nádraží | 11h04 | 22:35 Brussels-Midi | 2 changes | |
| rj 176 · ICE 554 · ICE 318 | 11:31 Prague hlavní nádraží | 10h55 | 22:26 Brussels-North | 2 changes | |
| rj 176 · ICE 554 · ICE 318 · IC 4544 | 11:31 Prague hlavní nádraží | 11h05 | 22:36 Brussels-Central | 3 changes | |
| rj 176 · ICE 554 · ICE 318 · IC 4544 | 11:31 Prague hlavní nádraží | 11h13 | 22:44 Brussels Congress | 4 changes | |
| R 688 · 5449 · S1 · ICE 1554 | 11:47 Prague hlavní nádraží | 17h00 | 04:47 Brussels-Midi | 7 changes | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Prague to Brussels by train, coach or flight
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sun
14 Dec
14 Dec
Mon
15 Dec
15 Dec
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03 Jan
How far in advance should I book train tickets from Prague to Brussels?
The best time to book your train from Prague to Brussels is 77 days before departure. See how prices for trains change on the Prague to Brussels route.
Prices are for one-way tickets for one passenger from Prague to Brussels per month. Insights are sourced from fares found by Omio users in the last 12 months. Current prices may differ as prices vary depending on the time of day, class or how far in advance you book your train from Prague to Brussels.
Trains
from £80Coaches
from £52Flights
from £172Journey information
Overview: Train from Prague to Brussels
Czechia
Belgium
Trains from Prague to Brussels run on average 5 times per day, taking around 13h 12m. Cheap train tickets for this journey start at £81 but you can travel from only £25 by coach.
The earliest train runs at 00:10, the last at 23:50. The fastest train covers the 717 km distance in 10h 55m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Coach from £25
Distance 717 km |
Average train duration 13h 12m |
Cheapest ticket price £81 |
Trains per day 5 |
Fastest train 10h 55m |
First train 00:10 |
Last train 23:50 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Coach from £25
Train companies: Deutsche Bahn, European Sleeper from Prague to Brussels trainsDeutsche Bahn, European Sleeper trains will get you between Prague and Brussels from £25. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
About
Deutsche Bahn (DB) is Germany’s main train operator, running around 40,000 domestic and international services each day. Its fleet includes a variety of train types: high-speed ICE (Intercity Express) trains, reaching up to 300 km/h; IC (Intercity) and EC (EuroCity) trains for long-distance travel; and IRE (Interregio-Express), RE (Regional Express), and RB (Regionalbahn) services for regional and local connections. While bathrooms are standard on all trains, amenities such as onboard restaurants and free Wi-Fi are available only on certain train types and routes. DB offers a wide range of fares, including Super Saver, Saver, and Flexible tickets, along with discount cards like the BahnCard 25, 50, and 100. Additional options include single tickets, day tickets, and group tickets. Popular routes include Berlin–Munich, Hamburg–Frankfurt, Cologne–Stuttgart, Berlin–Dresden, and Hamburg–Cologne, as well as numerous regional services across Germany.
Luggage & cancellation policy
Average Duration
10h 55m
Cheapest Price
£92
Deutsche Bahn frequency
4 a day
Luggage included
Passengers are allowed to bring hand luggage and one additional larger item free of charge, provided they can carry it themselves
Luggage storage
Luggage can be stored in overhead racks, under the seat, or in designated luggage areas near the doors or in the middle of the carriage.
Cancellation Policy
Tickets can be canceled based on their fare conditions as mentioned in what type of train tickets are refundable?
Refund
If DB cancels a train, passengers are entitled to a full refund of the ticket price.
Amenities on board the train
Wifi
Food sold onboard
Most ICE and many IC/EC trains have:
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Seat reservation
Second Class:
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Toilets
USB plugs
Accessibility
DB trains are equipped with facilities for passengers with reduced mobility, including wheelchair spaces, accessible restrooms, and assistance services.
Pets
Small pets (e.g. cats, small dogs, etc.):
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Quiet zone
European Sleeper
About
European Sleeper is a Belgian-Dutch train company launched in 2021, operating night train services between Germany and Belgium three times a week, with plans to expand to daily service and extend routes to cities such as Dresden and Prague. Passengers can choose from standard seats, couchettes, or sleeper cabins. Couchettes include free drinks and power outlets, while sleeper cabins offer power outlets and complimentary meals. All tickets are sold as Flex Night fares, which are non-exchangeable but can be canceled up to 48 hours before departure.
Luggage & cancellation policy
Average Duration
15h 25m
Cheapest Price
£46
European Sleeper frequency
1 a day
Luggage included
1 piece of hand luggage and 2 pieces of hold luggage included in ticket price
Luggage storage
Luggage racks above seats and at end of carriages
Cancellation Policy
Cancellation possible according to fare conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car serving breakfast, drinks and snacks available for purchase
Seat reservation
Seat or berth reservation mandatory and included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces available, accessible toilets, staff assistance
Pets
Small pets in carriers allowed for free, larger dogs require paid ticket
Quiet zone
FAQs: Prague to Brussels train
Find answers to the most common questions about traveling from Prague to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.
To explore Brussels' main attractions, including the Grand Place, Atomium, and various museums, a stay of 2 to 3 days is generally sufficient.
The cost of a train ticket from Prague to Brussels can vary. The cheapest tickets are usually available from £81, while the average price tends to be around £148.
Booking trains from Prague to Brussels in advance is advisable, especially during peak travel seasons or for long journeys, to ensure availability and secure better fares.
Explore the vibrant Marolles district, known for its eclectic mix of antique shops and street art. Enjoy a leisurely stroll through Parc du Cinquantenaire, home to impressive arches and museums. Sample Belgian chocolates at renowned chocolatiers, and discover the lively atmosphere of the Saint-Géry district with trendy bars and cafes. Attend a performance at the historic La Monnaie opera house. Visit Grand Place, a UNESCO World Heritage site, the Atomium for panoramic city views, the famous Manneken Pis statue, the Royal Palace of Brussels, and the Magritte Museum for surrealist art.
The train journey from Prague to Brussels covers a distance of 717 km and takes approximately 10h 55m. Trains run 5 per day.
The train station in Prague that goes to Brussels is Prague hlavní nádraží, and it arrives at Brussels-Midi.
A day trip from Prague to Brussels is not feasible as the journey takes 10h 55m one way. There are 5 train trips per day. The distance covered is 717 km.
The first train from Prague to Brussels leaves at 0:10.
Trains from Prague to Brussels run approximately 5 times per day.
The train journey from Prague to Brussels offers picturesque views, especially as it passes through the rolling hills and charming landscapes of the Czech Republic and Germany, before transitioning into the more urban scenery as it approaches Belgium.
The cheapest way to get from Prague to Brussels is by coach, costing approximately £25.
Yes, you can take the train from Prague to Brussels.
The train distance from Prague to Brussels is 717 km.
Yes, there is a night train from Prague to Brussels.
The last train from Prague to Brussels departs at 23:50.
To get from Prague to Brussels, you can choose from several travel options including train, coach and flight.
Yes, there is a direct train between Prague and Brussels. The service operates 0 times per day, provided by European Sleeper, European Sleeper.
popular train stations
Important Stations and Airports in Prague and Brussels
Prague
Brussels
The major train station for departures in Prague is Praha-Holesovice. Find all the information you need to know about services, amenities and connections at Praha-Holesovice for your trip from Prague to Brussels.
Praha-Holesovice
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation DeskLuggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 10:00 PM Monday - Sunday
Distance to city center
2 km
Number of platforms
4Wifi
- Free
Parking
- Parking is available 24/7 with access from Partyzánská street.
Dining
- Restaurant Na Kovárně
- Cross Club
Taxis
- Outside the main entrance.
Accessibility
- Ramps, restrooms.
WC
- CZK 10
Hotel
- Mama Shelter Prague
- Plaza Alta Hotel
- Hotel Belvedere
Lost and Found Office
- Located in the main hall
Car Rental
- Avis
- Budget
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, platform 1-4 for trains to Germany, Austria, and regional destinations
- Hall 2: ticket office and waiting area
Public transport options for Praha-Holesovice
- Metro: Line C
- Tram: Lines 6, 12, 17
- Bus: Several lines available
Praha Masarykovo Nádraží
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation DeskLuggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 10:00 PM Monday - Sunday
Number of platforms
5Wifi
- Free
Parking
- Parking is available nearby with several public parking options.
Dining
- Restaurant Kotleta
- Café Imperial
Taxis
- Outside the main entrance.
Accessibility
- Ramps.
WC
- CZK 10
Hotel
- Hotel Kings Court
- Grand Hotel Bohemia
- Hotel Paris Prague
Lost and Found Office
- Located in the main hall
Car Rental
- Avis
- Europcar
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, platform 1-5 for regional and suburban trains
Public transport options for Praha Masarykovo Nádraží
- Metro: Line B
- Tram: Lines 3, 5, 14, 24
- Bus: Several lines available
Praha-Vršovice
Amenities at train station
WifiLockersParkingDiningTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingInformation DeskLuggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 10:00 PM Monday - Sunday
Distance to city center
3 kmNumber of platforms
4Wifi
- Free
Parking
- Parking is available near the station, with access from Boženy Němcové street.
Dining
- Ansámbl
- Bad Flash Bar
- Café Sladkovský
Taxis
- Outside the main entrance.
Accessibility
- Ramps, restrooms.
WC
- CZK 10
Hotel
- Hotel Mars
- Hotel Slavia
- Hotel Nabucco
Lost and Found Office
- Located in the main hall
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, platforms 1-4 for regional and suburban trains
Public transport options for Praha-Vršovice
- Tram: Line 6, Line 7, Line 24
- Bus: Several lines available
- Train: Connections to Praha hlavní nádraží
The major train station for arrivals in Brussels is Brussels-Nord. Find all the information you need to know about services, amenities and connections at Brussels-Nord for your journey to Brussels from Prague.
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation DeskLuggage Cartsinformation
Ticket Office Hours
- 6:30 AM - 10:00 PM Monday - Sunday
Distance to city center
1 kmNumber of platforms
12Wifi
- Free
Parking
- The car park is open 7 days a week. Access is available via Rue du Progrès.
Dining
- Chabrol Brasserie
- Winok Café
- Félix Wine Bar
Taxis
- Outside the main entrance.
Accessibility
- Elevators, ramps.
WC
- €0.50
Hotel
- Hotel Progress
- Hilton Brussels City
- Hotel Siru
Lost and Found Office
- Located in the main hall
Car Rental
- Avis
- Europcar
- Hertz
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, platform 1-6 for international and intercity trains
- Hall 2: platform 7-12 for regional and local trains
Public transport options for Brussels-Nord
- Metro: Line 3, Line 4
- Tram: Line 25, Line 55
- Bus: Several lines available
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelTicket OfficeBike ParkingBike RentalCar RentalInformation Deskinformation
Ticket Office Hours
- Mon - Sun: 06:15 - 22:00
Wifi
- Free Wi-Fi available in Starbucks.
Lockers
- Luggage lockers are located on Level 0 near Platforms 1 and 2.
Dining
- Starbucks
- Brasserie 28 Brewery
- Panos
- Delitraiteur Eat & Go
Accessibility
- Station has a wide range of facilities for passengers with limited mobility: elevators and escalators to platforms, wheelchair lifts and mobile ramps, barrier-free toilets and accessible parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
Hotel
- Hilton Brussels Grand Palace
- Hotel NH Brussels Carrefour de l'Europe
- Hôtel The Moon
Ticket Office
- Mon - Sun: 06:15 - 22:00
Information Desk
- Travel Center / information desk is located on the left side from the main entrance.
Public transport options for Bruxelles-Central
- Metro lines: 1, 5
- Train lines: IC, Intercity Direct 9200, RER (S1, S2, S3, S6, S8, S10)
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelTicket OfficeBike ParkingBike RentalCar RentalInformation Deskinformation
Ticket Office Hours
- Mon - Sun: 05:45 - 21:30
Wifi
- Wi-Fi is available for a fee.
Lockers
- Baggage storage facility is located across from the Thalys business lounge.
Dining
- Pullman Hotel Bar
- Quick Gare du Midi
- Subway
- EXKi Zuid
- Starbucks
- Häagen-Dazs
- Sbarro
- The Coffee Club
- The Belgian Chocolate House
- PAUL
- & many more
Accessibility
- Station has a wide range of facilities for passengers with reduced mobility: elevators and escalators to all platforms, wheelchair lifts and mobile ramps, disabled toilet and parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
Hotel
- Les Lofts De Styliste
- Park Inn by Radisson Brussels Midi
- Pullman Brussels Centre Midi
Information Desk
- Located in the main concourse and next to the international platforms.
Most popular train connections from Prague
More options for your journey from Prague to Brussels
Here are some other resources that might have the information you need
Most popular trains to and from Brussels and Prague
Most popular train connections to Brussels
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