- Must visit
Städel Museum
Major art museum on the Museumsufer with European masterpieces from the Middle Ages to modern art in a substantial permanent collection.
Cheapest price on 08 Oct
£16
Average ticket price on 08 Oct
£93
Fastest journey on 08 Oct
7 h 3 m
Average journey duration on 08 Oct
7 h 11 m
Trains on 08 Oct
49
Distance
409 km
The best way to find a cheap train ticket from Prague to Frankfurt am Main is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Prague to Frankfurt am Main will cost around £93 if you buy it on the day, but you can find cheap train tickets today for only £16.
On Thu 08 Oct, we found 49 trains from Prague to Frankfurt am Main, including 3 direct services.
These direct trains cover the 409 km distance in an average of 7 h 11 m but if you time it right, some trains will get you there in just 7 h 3 m .
The slowest trains will take 7 h 13 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
LE232
LE232
LE232
EC 458 · ICE 699
EC 458 · ICE 699
RJ 174 · IC 2446 · ICE 695
RJ 172 · IC 2448 · ICE 697
RJ 176 · IC 2444 · ICE 693
RJ 382 · IC 2442 · ICE 691
RJ 178 · IC 2440 · ICE 599Trains from Prague to Frankfurt am Main run on average 17 times per day, taking around 7h 13m. Cheap train tickets for this journey start at £9 if you book in advance.
The earliest train runs at 00:01, the last at 23:57. The fastest train covers the 409 km distance in 6h 12m.
Distance 409 km |
Average train duration 7h 13m |
Cheapest ticket price £9 |
Trains per day 17 |
Fastest train 6h 12m |
First train 0:01 |
Last train 23:57 |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Sun |
Best time to book 70 days |
The table below shows live departures for Prague to Frankfurt am Main trains for today, Wednesday 7 October. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
EX 356 · 3572 · ICE 620 | On time 11:35 Prague hlavní nádraží | 7h27 | 19:02 Frankfurt (Main) Hbf | 2 changes | |
EX 356 · 3572 · ICE 620 | On time 11:35 Prague hlavní nádraží | 7h44 | 19:19 Frankfurt Airport long-distance station | 2 changes | |
RJ 176 · ICE 1554 | On time 12:31 Prague hlavní nádraží | 8h25 | 20:56 Frankfurt Airport long-distance station | 1 change | |
RJ 176 · ICE 1554 | On time 12:31 Prague hlavní nádraží | 8h06 | 20:37 Frankfurt (Main) Hbf | 1 change | |
RJ 176 · IC 2444 · ICE 693 · S9 | 12:31 Prague hlavní nádraží | 7h43 | 20:14 Frankfurt am Main Flughafen | 3 changes | |
RJ 176 · IC 2444 · ICE 693 | On time 12:31 Prague hlavní nádraží | 7h13 | 19:44 Frankfurt (Main) Hbf | 2 changes | |
R 688 · Os 28009 · S1 · ICE 1554 | On time 12:47 Prague hlavní nádraží | 8h09 | 20:56 Frankfurt Airport long-distance station | 3 changes | |
R 688 · Os 28009 · S1 · ICE 1554 | On time 12:47 Prague hlavní nádraží | 7h50 | 20:37 Frankfurt (Main) Hbf | 3 changes | |
EX 354 · 3576 · ICE 526 | On time 13:35 Prague hlavní nádraží | 7h27 | 21:02 Frankfurt (Main) Hbf | 2 changes | |
EX 354 · 3576 · ICE 526 | On time 13:35 Prague hlavní nádraží | 7h44 | 21:19 Frankfurt Airport long-distance station | 2 changes | |
RJ 174 · ICE 1552 | On time 14:41 Prague-Holešovice | 7h56 | 22:37 Frankfurt (Main) Hbf | 1 change | |
RJ 174 · ICE 1552 · S8 | 14:41 Prague-Holešovice | 8h18 | 22:59 Frankfurt am Main Flughafen | 2 changes | |
RJ 174 · IC 2446 · ICE 695 · S9 | 14:41 Prague-Holešovice | 7h33 | 22:14 Frankfurt am Main Flughafen | 3 changes | |
RJ 174 · IC 2446 · ICE 695 | On time 14:41 Prague-Holešovice | 7h03 | 21:44 Frankfurt (Main) Hbf | 2 changes | |
R 684 · Os 28011 · S1 · ICE 1552 | On time 14:47 Prague hlavní nádraží | 7h50 | 22:37 Frankfurt (Main) Hbf | 3 changes | |
R 684 · Os 28011 · S1 · ICE 1552 | 14:47 Prague hlavní nádraží | 8h12 | 22:59 Frankfurt am Main Flughafen | 4 changes | |
EX 352 · 3580 · ICE 522 | On time 15:35 Prague hlavní nádraží | 7h47 | 23:22 Frankfurt Airport long-distance station | 2 changes | |
EX 352 · 3580 · ICE 522 | On time 15:35 Prague hlavní nádraží | 7h30 | 23:05 Frankfurt (Main) Hbf | 2 changes | |
RJ 172 · IC 2448 · ICE 697 · S9 | 16:31 Prague hlavní nádraží | 8h43 | 1:14 Frankfurt am Main Flughafen | 3 changes | |
RJ 172 · IC 2448 · ICE 697 | On time 16:31 Prague hlavní nádraží | 8h07 | 0:38 Frankfurt (Main) Hbf | 2 changes | |
EC 458 · ICE 699 | On time 18:31 Prague hlavní nádraží | 7h40 | 2:11 Frankfurt (Main) Hbf | 1 change | |
EC 458 · ICE 699 | On time 18:31 Prague hlavní nádraží | 8h08 | 2:39 Frankfurt Airport long-distance station | 1 change | |
R 676 · Os 28015 · S1 · 16536 | On time 18:47 Prague hlavní nádraží | 8h48 | 3:35 Frankfurt South station | 5 changes | |
LE232 | 22:14 Praha-Vršovice | 9h08 | 7:22 Frankfurt South station | 0 changesdirect | |
LE232 | 22:32 Prague hlavní nádraží | 8h50 | 7:22 Frankfurt South station | 0 changesdirect | |
LE232 | 22:42 Prague-Holešovice | 8h40 | 7:22 Frankfurt South station | 0 changesdirect | |
| Thursday 8 October | |||||
EX 362 · 3560 · ICE 722 | On time 5:35 Prague hlavní nádraží | 7h44 | 13:19 Frankfurt Airport long-distance station | 2 changes | |
EX 362 · 3560 · ICE 722 | On time 5:35 Prague hlavní nádraží | 7h27 | 13:02 Frankfurt (Main) Hbf | 2 changes | |
RJ 384 · ICE 1650 | On time 6:31 Prague hlavní nádraží | 8h06 | 14:37 Frankfurt (Main) Hbf | 1 change | |
RJ 384 · ICE 1650 | On time 6:31 Prague hlavní nádraží | 8h25 | 14:56 Frankfurt Airport long-distance station | 1 change | |
RJ 384 · IC 2048 · ICE 597 | On time 6:31 Prague hlavní nádraží | 7h13 | 13:44 Frankfurt (Main) Hbf | 2 changes | |
RJ 384 · IC 2048 · ICE 597 · S9 | On time 6:31 Prague hlavní nádraží | 7h43 | 14:14 Frankfurt am Main Flughafen | 3 changes | |
R 696 · Os 28003 · S1 · ICE 1650 | On time 6:47 Prague hlavní nádraží | 7h50 | 14:37 Frankfurt (Main) Hbf | 3 changes | |
R 696 · Os 28003 · S1 · ICE 1650 | On time 6:47 Prague hlavní nádraží | 8h09 | 14:56 Frankfurt Airport long-distance station | 3 changes | |
EX 360 · 3564 · ICE 628 | On time 7:35 Prague hlavní nádraží | 7h44 | 15:19 Frankfurt Airport long-distance station | 2 changes | |
EX 360 · 3564 · ICE 628 | On time 7:35 Prague hlavní nádraží | 7h27 | 15:02 Frankfurt (Main) Hbf | 2 changes | |
RJ 178 · IC 2440 · ICE 599 | On time 8:31 Prague hlavní nádraží | 7h13 | 15:44 Frankfurt (Main) Hbf | 2 changes | |
RJ 178 · IC 2440 · ICE 599 · S8 | 8:31 Prague hlavní nádraží | 7h37 | 16:08 Frankfurt am Main Flughafen | 3 changes | |
EX 358 · 3568 · ICE 624 | On time 9:35 Prague hlavní nádraží | 7h44 | 17:19 Frankfurt Airport long-distance station | 2 changes | |
EX 358 · 3568 · ICE 624 | On time 9:35 Prague hlavní nádraží | 7h27 | 17:02 Frankfurt (Main) Hbf | 2 changes | |
RJ 382 · ICE 1556 | On time 10:31 Prague hlavní nádraží | 8h25 | 18:56 Frankfurt Airport long-distance station | 1 change | |
RJ 382 · ICE 1556 | On time 10:31 Prague hlavní nádraží | 8h06 | 18:37 Frankfurt (Main) Hbf | 1 change | |
RJ 382 · IC 2442 · ICE 691 | On time 10:31 Prague hlavní nádraží | 7h13 | 17:44 Frankfurt (Main) Hbf | 2 changes | |
RJ 382 · IC 2442 · ICE 691 · 29266 | On time 10:31 Prague hlavní nádraží | 7h34 | 18:05 Frankfurt am Main Flughafen | 3 changes | |
R 690 · Os 28007 · S1 · ICE 1556 | On time 10:47 Prague hlavní nádraží | 7h50 | 18:37 Frankfurt (Main) Hbf | 3 changes | |
R 690 · Os 28007 · S1 · ICE 1556 | On time 10:47 Prague hlavní nádraží | 8h09 | 18:56 Frankfurt Airport long-distance station | 3 changes | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Discover the best of Frankfurt am Main — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Frankfurt am Main trip today.
Major art museum on the Museumsufer with European masterpieces from the Middle Ages to modern art in a substantial permanent collection.
Extensive natural history museum with dinosaur skeletons, fossils and scientific exhibits, especially popular for families and rainy days.
Museum of modern and contemporary art known for its striking triangular building and rotating exhibitions near the old town.
Recreated old town quarter between Römer and the cathedral, with narrow lanes, traditional-style facades and small public squares for strolling.
Frankfurt’s central historic square, framed by timbered buildings and used for markets, events and some of the city’s best-known views.
Riverside museum district with promenades, major collections and broad Main views, ideal for a scenic walk between cultural stops.
A tart, slightly sparkling apple wine served in a ribbed glass. It is Frankfurt’s signature drink and a staple in traditional cider taverns.
Green herb sauce made with seven fresh herbs, traditionally served with boiled eggs and potatoes. It is one of Frankfurt’s best-known regional specialities.
Pork sausages, usually lightly smoked, served hot with bread, potato salad or sauerkraut. They are a classic everyday dish in Frankfurt and Hesse.
Casual market hall stand famous for Frankfurter sausages and quick local bites in the lively Kleinmarkthalle.
Traditional Apfelwein tavern in Sachsenhausen, known for Green Sauce, sausages and a lively local atmosphere.
Historic cider house serving classic Frankfurt dishes and apple wine in a busy, wood-panelled setting popular with locals and visitors.
Moderate for Germany: hotels and dining cost more than smaller cities, but public transport is efficient and many everyday meals remain reasonably priced.
Service is not usually included. Round up or tip about 5-10% in restaurants, round up taxi fares, and leave small change in cafés.
Official public transport app
Frankfurt am Main Flughafen Regionalbahnhof -> Frankfurt (Main) Hauptbahnhof
The most popular day trips by train from Frankfurt am Main are Cologne, Mainz, Wiesbaden, Heidelberg and Mannheim. Find out what you can do in these day trip destinations and how to book your train from Frankfurt am Main on Omio.

Cologne is known for its towering cathedral, Roman heritage and relaxed Rhineland spirit. Museums, riverfront views and a strong brewing culture give the city an open, sociable feel.
There are 48 trains per day. The earliest train runs at 00:01, the last at 23:58. The fastest train covers the 153 km distance in 45m.

Mainz on the Rhine is known for its Roman past, Gutenberg heritage and relaxed wine culture. Its old town, cathedral and riverside give the state capital a lively but easy-going feel.
There are 1 trains per day. The earliest train runs at 00:08, the last at 23:44. The fastest train covers the 32 km distance in 31m.

Wiesbaden is known for its thermal springs, stately architecture and refined spa-town character. Set near the Rhine, it blends leafy parks, elegant squares and a calm, affluent atmosphere.
There are 1 trains per day. The earliest train runs at 00:13, the last at 23:39. The fastest train covers the 31 km distance in 29m.

Heidelberg is a historic university city on the River Neckar, known for its baroque Altstadt and Heidelberg Castle. A large student population keeps the city lively, while riverside views and the Philosophenweg reflect its Romantic past.
There are 12 trains per day. The earliest train runs at 00:01, the last at 23:57. The fastest train covers the 79 km distance in 32m.

Mannheim is known for its grid-plan centre, industrial heritage and confident cultural life. The Baroque palace, the Wasserturm and a strong music scene give the city a practical yet distinctive character.
There are 18 trains per day. The earliest train runs at 00:01, the last at 23:58. The fastest train covers the 70 km distance in 29m.
Find answers to the most common questions about traveling from Prague to Frankfurt am Main by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Frankfurt am Main, this guide helps you travel smarter and with confidence.

Most Prague to Frankfurt am Main trains use the Praha hlavní nádraží to Frankfurt (Main) Hbf station pair, with some services arriving at Frankfurt Flughafen Fernbf. Use this guide to compare Prague and Frankfurt am Main train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Praha hlavní nádraží is 1 km from Prague city centre. Public transport options include:
Praha hlavní nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk and Luggage Carts.
Food options include: Restaurant Fantova Kavárna, Sushi Time
Free. ATMs are available in the train station.
Ticket office support is available at Praha hlavní nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha hlavní nádraží. Lost and found is available at the station.
Available at Praha hlavní nádraží: Parking, Taxis, WC.
Available at Praha hlavní nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha hlavní nádraží: Elevators, ramps.
Nearby hotels include Hotel Esplanade Prague, Falkensteiner Hotel Maria Prag, Hotel City Central.
Praha-Holesovice is 2 km from Prague city centre. Public transport options include:
Praha-Holesovice has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk and Luggage Carts.
Food options include: Restaurant Na Kovárně, Cross Club
Free. ATMs are available in the train station.
Ticket office support is available at Praha-Holesovice. Information desks are located in the main hall.
Luggage storage is available at Praha-Holesovice. Lost and found is available at the station.
Available at Praha-Holesovice: Parking, Taxis, WC.
Available at Praha-Holesovice: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha-Holesovice: Ramps, restrooms.
Nearby hotels include Mama Shelter Prague, Plaza Alta Hotel, Hotel Belvedere.
Praha Masarykovo Nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk and Luggage Carts.
Food options include: Restaurant Kotleta, Café Imperial
Free. ATMs are available in the train station.
Ticket office support is available at Praha Masarykovo Nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha Masarykovo Nádraží. Lost and found is available at the station.
Available at Praha Masarykovo Nádraží: Parking, Taxis, WC.
Available at Praha Masarykovo Nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha Masarykovo Nádraží: Ramps.
Nearby hotels include Hotel Kings Court, Grand Hotel Bohemia, Hotel Paris Prague.
Frankfurt (Main) Hbf is 1 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt (Main) Hbf has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental and Information Desk.
Food options include: asiagourmet, Burger King, Ciao Bella, Coffee Fellows, Crepes de France Express, dean&david, Starbucks, Uddin's Sky Sportsbar, McDonald's, Dunkin Donuts, & many more
Free Wi-Fi in the station. ATMs are available at Frankfurt (Main) Hbf.
Ticket office support is available at Frankfurt (Main) Hbf. Information desks are located opposite Platforms 12 and 13.
Luggage storage is luggage lockers are located in the main hall. Lost and found is available at the station.
Available at Frankfurt (Main) Hbf: Parking, Taxis, WC.
Available at Frankfurt (Main) Hbf: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Frankfurt (Main) Hbf: Step-free access and step markings. Contact the Mobility Service Centre at +49 3065212888 or [email protected].
Nearby hotels include Hotel Cristall, Grand Hotel Empire, Hotel Carlton.
Frankfurt Flughafen Fernbf is 10 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt Flughafen Fernbf has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk and Luggage Carts.
Food options include: Restaurant Käfer's, McDonald's, Asia Snack Box
Free. ATMs are available in the train station.
Ticket office support is available at Frankfurt Flughafen Fernbf. Information desks are located in the main hall.
Luggage storage is available at Frankfurt Flughafen Fernbf. Lost and found is available at the station.
Available at Frankfurt Flughafen Fernbf: Parking, Taxis, WC.
Available at Frankfurt Flughafen Fernbf: Bike Parking, Car Rental.
Accessibility facilities are available at Frankfurt Flughafen Fernbf: Elevators, ramps.
Nearby hotels include Sheraton Frankfurt Airport Hotel, Hilton Frankfurt Airport, Hilton Garden Inn Frankfurt Airport.
Frankfurt (M) Flughafen Regionalbf is 10 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt (M) Flughafen Regionalbf has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk and Luggage Carts.
Food options include: Restaurant Käfer's, McDonald's, Asia Snack Box
Free. ATMs are available in the train station.
Ticket office support is available at Frankfurt (M) Flughafen Regionalbf. Information desks are located in the main hall.
Luggage storage is available at Frankfurt (M) Flughafen Regionalbf. Lost and found is available at the station.
Available at Frankfurt (M) Flughafen Regionalbf: Parking, Taxis, WC.
Available at Frankfurt (M) Flughafen Regionalbf: Bike Parking, Car Rental.
Accessibility facilities are available at Frankfurt (M) Flughafen Regionalbf: Elevators, ramps, restrooms.
Nearby hotels include Sheraton Frankfurt Airport Hotel, Hilton Frankfurt Airport, Steigenberger Airport Hotel.
Here are some other resources that might have the information you need