The cheapest and fastest trains from Mannheim to Prague
Cheapest price
£46
Average price
£123
Fastest journey
8 h 5 m
Average duration
8 h 35 m
Trains per day
32
Distance
431 km
The best way to find a cheap train ticket from Mannheim to Prague is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Mannheim to Prague will cost around £123 if you buy it on the day, but you can find cheap train tickets today for only £46.
To travel from Mannheim to Prague you need to make at least 3 changes.
ICE 205 · EC 45922:2910h56Mannheim Hbf9:25Prague hlavní nádraží£461One-way1 change
S1 · 19072 · ICE 589 · 357713:388h44Mannheim Hbf22:22Prague hlavní nádraží£551One-way4 changes
R 4586 · R 15544 · EC 45922:3810h47Mannheim Hbf9:25Prague hlavní nádraží£561One-way2 changes
R 4586 · ICE 1272 · EC 45922:3810h47Mannheim Hbf9:25Prague hlavní nádraží£561One-way2 changes
S9 · EC 45921:5311h32Mannheim Hbf9:25Prague hlavní nádraží£651One-way1 change
R 4656 · ICE 527 · R 3565 · EC 3578:168h05Mannheim Hbf16:21Prague hlavní nádraží£1571One-way3 changes
S 38115 · R 19064 · ICE 585 · R 35699:388h43Mannheim Hbf18:21Prague hlavní nádraží£1651One-way4 changes
S 38119 · ICE 219 · R 88619 · R 357311:388h43Mannheim Hbf20:21Prague hlavní nádraží£1811One-way4 changes
S1 · 19068 · ICE 587 · 357311:388h43Mannheim Hbf20:21Prague hlavní nádraží£661One-way4 changes
S1 · 19064 · ICE 621 · 35699:388h43Mannheim Hbf18:21Prague hlavní nádraží£741One-way4 changes
Travel Information
Compare coach, train and flight for Mannheim to Prague
Omio recommends booking the train as it is the most popular option from Mannheim to Prague among Omio's users. If you are prioritising price take the coach with prices starting from £23. For those with little time consider booking a flight which can get you there in 2h 2m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a coach costs an average of £23, and a flight costs an average of £114.
Distance: 431 km
Compare train with
Most popular Train | Coach | Flight |
|---|---|---|
£87 Average Price | £38 Average Price Cheapest | £164 Average Price |
9h 42m Average total duration 9h 12m Onboard + 30m Additional time* | 6h 53m Average total duration 6h 23m Onboard + 30m Additional time* | 5h 2m Average total duration Fastest 2h 2m Onboard + 3h 0m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions | 1.3 - 2.6kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Mannheim to Prague train times
The table below shows live departures for Mannheim to Prague trains for tomorrow, Sunday 31 May. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
R 4656 · ICE 527 · R 3565 · EC 357 | 8:16 Mannheim Hbf | 8h05 | 16:21 Prague hlavní nádraží | 3 changes | |
ICE 614 · 29507 · ICE 692 · IC 2443 | On time 8:38 Mannheim Hbf | 8h47 | 17:25 Prague hlavní nádraží | 4 changes | |
R 4560 · ICE 759 · rj 177 | 9:35 Mannheim Hbf | 9h40 | 19:15 Prague-Holešovice | 2 changes | |
4560 · ICE 621 · 3569+ 359 | 9:35 Mannheim Hbf | 8h46 | 18:21 Prague hlavní nádraží | 3 changes | |
R 4560 · ICE 621 · R 3569 · EC 359 | 9:35 Mannheim Hbf | 8h46 | 18:21 Prague hlavní nádraží | 3 changes | |
S 38115 · R 19064 · ICE 585 · R 3569 | On time 9:38 Mannheim Hbf | 8h43 | 18:21 Prague hlavní nádraží | 4 changes | |
S1 · 19064 · ICE 621 · 3569 | 9:38 Mannheim Hbf | 8h43 | 18:21 Prague hlavní nádraží | 4 changes | |
ICE 915 · EC 361 | On time 10:56 Mannheim Hbf | 9h25 | 20:21 Prague hlavní nádraží | 1 change | |
ICE 915+ 361 | On time 10:56 Mannheim Hbf | 9h25 | 20:21 Prague hlavní nádraží | 1 change | |
R 4564 · ICE 1651 · rj 385 | 11:35 Mannheim Hbf | 9h50 | 21:25 Prague hlavní nádraží | 2 changes | |
4564 · ICE 1651 · ECE 385 | 11:35 Mannheim Hbf | 9h50 | 21:25 Prague hlavní nádraží | 2 changes | |
4564 · ICE 623 · 3573+ 361 | 11:35 Mannheim Hbf | 8h46 | 20:21 Prague hlavní nádraží | 3 changes | |
R 4564 · ICE 623 · R 3573 · EC 361 | 11:35 Mannheim Hbf | 8h46 | 20:21 Prague hlavní nádraží | 3 changes | |
S1 · 19068 · ICE 587 · 3573 | 11:38 Mannheim Hbf | 8h43 | 20:21 Prague hlavní nádraží | 4 changes | |
S 38119 · ICE 219 · R 88619 · R 3573 | On time 11:38 Mannheim Hbf | 8h43 | 20:21 Prague hlavní nádraží | 4 changes | |
ICE 610 · ICE 1517 · ICE 598 · IC 2049 | On time 12:39 Mannheim Hbf | 8h46 | 21:25 Prague hlavní nádraží | 4 changes | |
ICE 610 · ICE 1517 · ICE 598 · IC 2049 | On time 12:39 Mannheim Hbf | 8h46 | 21:25 Prague hlavní nádraží | 4 changes | |
ICE 517+ 363 | On time 13:28 Mannheim Hbf | 8h54 | 22:22 Prague hlavní nádraží | 1 change | |
ICE 517 · EC 363 | On time 13:28 Mannheim Hbf | 8h54 | 22:22 Prague hlavní nádraží | 1 change | |
R 4568 · ICE 627 · R 3577 · EC 363 | 13:35 Mannheim Hbf | 8h47 | 22:22 Prague hlavní nádraží | 3 changes | |
4568 · ICE 1653 · RJ 179 | On time 13:35 Mannheim Hbf | 9h56 | 23:31 Prague hlavní nádraží | 2 changes | |
R 4568 · ICE 1653 · rj 179 | 13:35 Mannheim Hbf | 9h56 | 23:31 Prague hlavní nádraží | 2 changes | |
4568 · ICE 627 · 3577+ 363 | 13:35 Mannheim Hbf | 8h47 | 22:22 Prague hlavní nádraží | 3 changes | |
S1 · 19072 · ICE 589 · 3577 | 13:38 Mannheim Hbf | 8h44 | 22:22 Prague hlavní nádraží | 4 changes | |
4576 · ICE 1567 · S1 · 28018 | 17:35 Mannheim Hbf | 14h35 | 8:10 Prague hlavní nádraží | 4 changes | |
R 4576 · ICE 1657 · S 31701 · Os 28018 | 17:35 Mannheim Hbf | 14h35 | 8:10 Prague hlavní nádraží | 4 changes | |
S9 · EC 459 | On time 21:53 Mannheim Hbf | 11h32 | 9:25 Prague hlavní nádraží | 1 change | |
ICE 615 · EC 351 | On time 21:58 Mannheim Hbf | 12h23 | 10:21 Prague hlavní nádraží | 1 change | |
ICE 615+ 351 | On time 21:58 Mannheim Hbf | 12h23 | 10:21 Prague hlavní nádraží | 1 change | |
ICE 205 · EC 459 | Delayed 20:59 22:29Mannheim Hbf | 10h56 | 9:25 Prague hlavní nádraží | 1 change | |
R 4586 · R 15544 · EC 459 | On time 22:38 Mannheim Hbf | 10h47 | 9:25 Prague hlavní nádraží | 2 changes | |
R 4586 · ICE 1272 · EC 459 | On time 22:38 Mannheim Hbf | 10h47 | 9:25 Prague hlavní nádraží | 2 changes | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mannheim to Prague by coach, train or flight
Compare coach, train and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
31 May
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Why should you book Mannheim to Prague trains with Omio?
Why book with Omio vs alex-Länderbahn und Vogtlandbahn-GmbH?
- Compare with other providers: On Omio, you can not only buy tickets for alex-Länderbahn und Vogtlandbahn-GmbH, but also compare tickets for the likes of Deutsche Bahn, České dráhy, ÖBB or Deutsche Bahn Intercity (DB IC) to find the best option for your trip from Mannheim to Prague.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare alex-Länderbahn und Vogtlandbahn-GmbH with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Mannheim to Prague.
Why book with Omio over Wanderu, Trainline or Raileurope?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Deutsche Bahn, České dráhy, ÖBB or Deutsche Bahn Intercity (DB IC) to find the best option for your trip from Mannheim to Prague.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Mannheim to Prague.
How far in advance should I book train tickets from Mannheim to Prague?
Journey information
Overview: Train from Mannheim to Prague
Trains from Mannheim to Prague run on average 11 times per day, taking around 9h 12m. Cheap train tickets for this journey start at £43 but you can travel from only £23 by coach.
The earliest train runs at 00:30, the last at 23:50. The fastest train covers the 431 km distance in 7h 46m.
Distance 431 km |
Average train duration 9h 12m |
Cheapest ticket price £43 |
Trains per day 11 |
Fastest train 7h 46m |
First train 0:30 |
Last train 23:50 |
Cheapest Month May |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Thu |
Best time to book 42 days |
Train companies: alex-Länderbahn und Vogtlandbahn-GmbH, Deutsche Bahn, České dráhy, ÖBB, Deutsche Bahn Intercity (DB IC) from Mannheim to Prague trainsalex-Länderbahn und Vogtlandbahn-GmbH, Deutsche Bahn, České dráhy, ÖBB, Deutsche Bahn Intercity (DB IC) trains will get you between Mannheim and Prague from £23. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
alex-Länderbahn und Vogtlandbahn-GmbH
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
České dráhy
ÖBB
Deutsche Bahn Intercity (DB IC)
FAQs: Mannheim to Prague train
Find answers to the most common questions about traveling from Mannheim to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Mannheim and Prague
- Monday: 06:00 - 21:00
- Tuesday: 06:00 - 21:00
- Wednesday: 06:00 - 21:00
- Thursday: 06:00 - 21:00
- Friday: 06:00 - 21:00
- Saturday: 08:00 - 20:30
- Sunday: 08:00 - 20:30
- Safran Persisch-Afghanische Spezialitäten
- Corner
- Liman Döner
- Kaschmir-Tandoori
- Central
- Leonardo Hotel Mannheim City Center
- InterCityHotel Mannheim
- City Hotel
- Corner
- Brasserie Bernstein
- Liman Döner
- Uzun Imbiss-Bäckerei
- Best Western Hotel Mannheim City
- Knackpunkt
- Schloss am Meer
- Playa del MA
- Manufaktur Mannheimer Genusswerk
- Corniche Hotel
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, 24 hours a day. Access via Wilsonova Street.
- Restaurant Fantova Kavárna
- Sushi Time
- Outside the main entrance.
- Elevators, ramps.
- CZK 10
- Hotel Esplanade Prague
- Falkensteiner Hotel Maria Prag
- Hotel City Central
- Cost CZK 100
- Located in the main hall
- Located in the main hall
- Avis
- Europcar
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-7 for trains to Germany, Austria, Slovakia, and regional destinations
- Hall 2: Metro connections
- Metro: Line C
- Tram: Lines 5, 9, 26
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available nearby with several public parking options.
- Restaurant Kotleta
- Café Imperial
- Outside the main entrance.
- Ramps.
- CZK 10
- Hotel Kings Court
- Grand Hotel Bohemia
- Hotel Paris Prague
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for regional and suburban trains
- Metro: Line B
- Tram: Lines 3, 5, 14, 24
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available 24/7 with access from Partyzánská street.
- Restaurant Na Kovárně
- Cross Club
- Outside the main entrance.
- Ramps, restrooms.
- CZK 10
- Mama Shelter Prague
- Plaza Alta Hotel
- Hotel Belvedere
- Located in the main hall
- Avis
- Budget
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for trains to Germany, Austria, and regional destinations
- Hall 2: ticket office and waiting area
- Metro: Line C
- Tram: Lines 6, 12, 17
- Bus: Several lines available
Most popular train connections from Mannheim
More options for your journey from Mannheim to Prague
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