- Must visit
Musée des Beaux-Arts de Lyon
Leading fine arts museum in a former abbey, with strong collections of painting, sculpture, antiquities and decorative arts in a grand setting.
Cheapest price on 10 Oct
£74
Average ticket price on 10 Oct
£105
Fastest journey on 10 Oct
5 h 16 m
Average journey duration on 10 Oct
7 h 38 m
Trains on 10 Oct
14
Distance
498 km
The best way to find a cheap train ticket from Mannheim to Lyon is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Mannheim to Lyon will cost around £105 if you buy it on the day, but you can find cheap train tickets today for only £74.
On Sat 10 Oct, we found 14 trains from Mannheim to Lyon, including 1 direct services.
These direct trains cover the 498 km distance in an average of 7 h 38 m but if you time it right, some trains will get you there in just 5 h 16 m .
The slowest trains will take 9 h 29 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
ICE 273+
87410+
12177
ICE 273+
87410+
5537
ICE 275+
87414+
5537
ICE 275+
87414+
12177
ICE 101 · 4719+
87422+
5537
9580
9556+
6617
S3+
TGV 9576+
9879
ICE 101 · 4719+
87422+
9879
S3+
12177+
TGV 9576Trains from Mannheim to Lyon run on average 16 times per day, taking around 5h 27m. Cheap train tickets for this journey start at £6 if you book in advance.
There are 1 trains per day. The earliest train runs at 03:15, the last at 23:00. The fastest train covers the 498 km distance in 4h 46m.
Distance 498 km |
Average train duration 5h 27m |
Cheapest ticket price £6 |
Trains per day 16 |
Direct trains 1 |
Fastest train 4h 46m |
First train 3:15 |
Last train 23:00 |
Cheapest Month Sept |
Cheapest Day Wed |
High Season Jul - Sept |
Low Season Oct - Dec |
Busiest Day Wed |
Least Busy Day Thu |
Best time to book 14 days |
The table below shows live departures for Mannheim to Lyon trains for tomorrow, Saturday 10 October. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
ICE 273+ 87410+ 5537 | 6:32 Mannheim Hbf | 11h27 | 17:59 Lyon Part Dieu | 2 changes | |
ICE 273+ 87410+ 12177 | 6:32 Mannheim Hbf | 11h27 | 17:59 Lyon Part Dieu | 2 changes | |
ICE 273+ 87410+ 9879 | 6:32 Mannheim Hbf | 10h31 | 17:03 Lyon Part Dieu | 2 changes | |
ICE 275+ 87414+ 5537 | 7:23 Mannheim Hbf | 10h36 | 17:59 Lyon Part Dieu | 2 changes | |
ICE 275+ 87414+ 12177 | 7:23 Mannheim Hbf | 10h36 | 17:59 Lyon Part Dieu | 2 changes | |
ICE 275+ 87414+ 9879 | 7:23 Mannheim Hbf | 9h40 | 17:03 Lyon Part Dieu | 2 changes | |
ICE 101 · 4719+ 87422+ 5537 | 8:25 Mannheim Hbf | 9h34 | 17:59 Lyon Part Dieu | 3 changes | |
ICE 101 · 4719+ 87422+ 9879 | 8:25 Mannheim Hbf | 8h38 | 17:03 Lyon Part Dieu | 3 changes | |
ICE 101 · 4719+ 87422+ 12177 | 8:25 Mannheim Hbf | 9h34 | 17:59 Lyon Part Dieu | 3 changes | |
S3+ 9879+ TGV 9576 | 8:30 Mannheim Hbf | 8h33 | 17:03 Lyon Part Dieu | 2 changes | |
S3+ 5537+ TGV 9576 | 8:30 Mannheim Hbf | 9h29 | 17:59 Lyon Part Dieu | 2 changes | |
S3+ 12177+ TGV 9576 | 8:30 Mannheim Hbf | 9h29 | 17:59 Lyon Part Dieu | 2 changes | |
9556+ 6617 | 9:40 Mannheim Hbf | 6h16 | 15:56 Lyon Part Dieu | 1 change | |
9580 | 14:42 Mannheim Hbf | 5h16 | 19:58 Lyon Part Dieu | 0 changesdirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Leading fine arts museum in a former abbey, with strong collections of painting, sculpture, antiquities and decorative arts in a grand setting.
Modern museum exploring natural history, science and societies through immersive design and striking architecture at the tip of the Presqu’île.
Museum dedicated to cinema and miniature art, featuring detailed sets, props and displays linked to the Lumière brothers and visual storytelling.
Renaissance quarter of lanes, courtyards and traboules. It is one of the best areas for walking, architecture and discovering historic Lyon at street level.
Central square known for open space, fountains and major events. A practical starting point for exploring Presqu’île and the city centre on foot.
Slopes district of stairways, murals and creative energy. It blends local life, independent shops and striking urban views between Rhône and Saône.
Rich fish stew from the Lyon area, usually made with freshwater fish, crayfish and vegetables, often finished with cream. A regional speciality tied to local rivers.
Soft dumplings made with pike and choux pastry, typically baked with creamy sauce. A classic Lyonnais dish served in bouchons and family restaurants.
Warm salad of frisée lettuce with bacon lardons, croutons and a poached egg. It is a staple of traditional bouchon cooking in Lyon.
Refined dining room known for elegant French cuisine rooted in Lyon tradition. Suitable for a special meal with polished service.
Well-known traditional bouchon with hearty regional cooking and an old Lyon atmosphere. Good for charcuterie, offal dishes and local desserts.
Historic bouchon serving classic Lyonnais dishes in a warm, traditional setting. A reliable choice for quenelles, salads and local specialities.
Moderate for France: hotels and dining are cheaper than Paris, but central stays and bouchons still add up. Public transport is good value.
Service is included in restaurant bills. Rounding up or leaving 5-10% for great service is appreciated. Round up for taxis; cafés often just leave small change.
Official public transport app
Lyon Part-Dieu -> Place Bellecour, Lyon
The most popular day trips by train from Lyon are Paris, Avignon, Grenoble, Annecy and Dijon. Find out what you can do in these day trip destinations and how to book your train from Lyon on Omio.

Paris is known for elegant streets, major museums and a cultural identity shaped by art, fashion and café life. Along the Seine, grand landmarks sit beside neighbourhoods that still feel local and lived in.
There are 34 trains per day. The earliest train runs at 05:14, the last at 21:30. The fastest train covers the 393 km distance in 1h 49m.

Avignon is a historic Provençal city on the Rhône, known for the Palais des Papes and the Pont d’Avignon. Its walled centre blends medieval grandeur with busy squares, cafés and a strong theatre culture, especially during the Festival d’Avignon.
There are 19 trains per day. The earliest train runs at 05:35, the last at 22:24. The fastest train covers the 200 km distance in 49m.

Grenoble is an Alpine city known for its universities, research centres and lively student life. Set between three mountain ranges, it combines a compact old town with a practical, outdoors-focused character.
There are 11 trains per day. The earliest train runs at 05:21, the last at 23:26. The fastest train covers the 93 km distance in 1h 21m.

Annecy is known for its old town, winding canals and the deep blue waters of Lake Annecy. With Alpine scenery framing medieval streets, it feels both elegant and relaxed.
There are 4 trains per day. The earliest train runs at 05:00, the last at 23:01. The fastest train covers the 100 km distance in 1h 38m.

Dijon is known for mustard, Burgundy wine and a handsome medieval centre. Its timber-framed streets and ducal buildings give the city a refined yet lived-in feel.
There are 12 trains per day. The earliest train runs at 05:16, the last at 21:29. The fastest train covers the 175 km distance in 1h 25m.
Find answers to the most common questions about traveling from Mannheim to Lyon by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Most Mannheim to Lyon trains use the Mannheim Hbf to Lyon Part Dieu station pair, with some services arriving at Lyon-Perrache. Use this guide to compare Mannheim and Lyon train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Mannheim Hbf is 2 km from Mannheim city centre. Public transport options include:
Mannheim Hbf has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental and Information Desk.
Food options include: Safran Persisch-Afghanische Spezialitäten, Corner, Liman Döner, Kaschmir-Tandoori
Wi-Fi is available at Mannheim Hbf. ATMs are available at Mannheim Hbf.
Ticket office support is available at Mannheim Hbf. Information desks are available at Mannheim Hbf.
Luggage storage is available at Mannheim Hbf. Lost and found is available at the station.
Available at Mannheim Hbf: Parking, Taxis, WC.
Available at Mannheim Hbf: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Mannheim Hbf.
Nearby hotels include Central, Leonardo Hotel Mannheim City Center, InterCityHotel Mannheim, City Hotel.
Lyon Part Dieu is 1 km from Lyon city centre. Public transport options include:
Lyon Part Dieu has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental and Information Desk.
Food options include: Alto Café, Paul, Paul The Café, Starbucks, Exki, Sushi Shop, Carrefour
Free unlimited WiFi. ATMs are located in the station's main hall.
The ticket office is open Mon - Wed: 05:00 - 20:45, Thu - Sat: 05:00 - 21:45, Sun: 06:45 - 21:45. Information desks are located in the station's main hall. .
Luggage storage is luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk. .
Available at Lyon Part Dieu: Parking, Taxis, WC.
Available at Lyon Part Dieu: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Lyon Part Dieu: Complimentary personalized care is available.
Nearby hotels include Radisson Blu Hotel Lyon, Mercure Lyon Center, ibis Styles Lyon Center.
Lyon-Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon-Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental and Information Desk.
Food options include: PAUL
Free, unlimited Wi-Fi is available after creating an account and connecting to "CONNECTION.". ATMs are aTM machine is located in Hall Level 2 in front of the PAUL bakery.
The ticket office is open Mon - Fri: 10:00 - 18:00. Information desks are information services are available at the ticket office, located in Hall Level 2.
Available at Lyon-Perrache: Parking, Taxis, WC.
Available at Lyon-Perrache: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Lyon-Perrache: Hearing, mobility, and visual disability assistance. Accessibility available with elevator, ramp or step-free access, barrier-free toilets.
Nearby hotels include Mercure Lyon Centre Chateau Perrache, Hotel De Normandie, InterContinental Lyon-Hotel Dieu.
Here are some other resources that might have the information you need