The cheapest and fastest trains from Karlsruhe to Prague
Cheapest price
£32
Average price
£53
Fastest journey
8 h 17 m
Average duration
8 h 43 m
Trains per day
5
Distance
452 km
The best way to find a cheap train ticket from Karlsruhe to Prague is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Karlsruhe to Prague will cost around £53 if you buy it on the day, but you can find cheap train tickets today for only £32.
Of the 5 trains that leave Karlsruhe for Prague every day 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct trains cover the 452 km distance in an average of 8 h 43 m but if you time it right, some trains will get you there in just 8 h 17 m .
The slowest trains will take 9 h 16 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
11:058h17Karlsruhe19:22Prague£321One-way0 changes
7:058h17Karlsruhe15:22Prague£411One-way0 changes
8:069h15Karlsruhe17:21Prague£491One-way0 changes
13:2311h17Karlsruhe0:40Prague£581One-way0 changes
13:598h32Karlsruhe22:31Prague£841One-way0 changes
7:058h17Karlsruhe15:22Prague£411One-way0 changes
11:058h17Karlsruhe19:22Prague£321One-way0 changes
13:598h32Karlsruhe22:31Prague£841One-way0 changes
8:069h15Karlsruhe17:21Prague£491One-way0 changes
8:599h16Karlsruhe18:15Prague£1181One-way0 changes
Travel Information
Compare train and coach for Karlsruhe to Prague
Omio recommends booking the train as it is the most popular option from Karlsruhe to Prague among Omio's users. If you are prioritising price take the coach with prices starting from £25. For those with little time consider booking a coach which can get you there in 7h 25m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a coach costs an average of £25, and a train costs an average of £27.
Distance: 452 km
Compare train with
Most popular Train | Coach |
|---|---|
£56 Average Price | £39 Average Price Cheapest |
9h 49m Average total duration 9h 19m Onboard + 30m Additional time* | 7h 55m Average total duration Fastest 7h 25m Onboard + 30m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.5 - 1.1kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Karlsruhe to Prague train times
The table below shows live departures for Karlsruhe to Prague trains for today, Saturday 18 April. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
ICE 376 · ICE 1557 · BUS 10383 · RJ 383 | Delayed 6:18 7:59Karlsruhe Hbf | 9h26 | 17:25 Prague hlavní nádraží | 3 changes | |
ICE 267+ 22359+ Bus RE25 · EX 359 | On time 8:05 Karlsruhe Hbf | 10h16 | 18:21 Prague hlavní nádraží | 3 changes | |
IC 2067 · ICE 513 · ALX 22359 · EC 60359 | On time 9:06 Karlsruhe Hbf | 9h15 | 18:21 Prague hlavní nádraží | 4 changes | |
IC 2067 · ICE 513+ 22359+ Bus RE25 | On time 9:06 Karlsruhe Hbf | 9h15 | 18:21 Prague hlavní nádraží | 4 changes | |
15839 · 19064 · ICE 585 · 3569 | On time 9:15 Karlsruhe Hbf | 9h06 | 18:21 Prague hlavní nádraží | 5 changes | |
FlixTrain+ FlixBus | 10:26 Karlsruhe Hbf | 11h14 | 21:40 Praha, ÚAN Florenc | 1 change | |
ICE 798 · RJ 385 | On time 10:39 Karlsruhe Hbf | 10h46 | 21:25 Prague hlavní nádraží | 1 change | |
ICE 200 · ICE 690 · IC 2441 · RJ 177 | On time 10:59 Karlsruhe Hbf | 8h16 | 19:15 Prague-Holešovice | 3 changes | |
IC 2069 · ICE 515 · ALX 22361 · EC 60361 | On time 11:06 Karlsruhe Hbf | 9h15 | 20:21 Prague hlavní nádraží | 4 changes | |
ICE 372 · ICE 1651 · S 31755 · Os 28012 | On time 11:59 Karlsruhe Hbf | 9h11 | 21:10 Prague hlavní nádraží | 4 changes | |
Find all the dates and times for this journey
Compare prices and tickets Karlsruhe to Prague by train or coach
Compare train and coach prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
19 Apr
20 Apr
21 Apr
22 Apr
23 Apr
24 Apr
25 Apr
26 Apr
27 Apr
28 Apr
29 Apr
30 Apr
01 May
02 May
03 May
04 May
05 May
06 May
07 May
08 May
09 May
Why should you book Karlsruhe to Prague trains with Omio?
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of alex-Länderbahn und Vogtlandbahn-GmbH or České dráhy to find the best option for your trip from Karlsruhe to Prague.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are train and bus to ensure you get the best deal for traveling from Karlsruhe to Prague.
Why book with Omio over Trainline, Wanderu or Raileurope?
- Compare with other providers: On Omio, you can also compare tickets for the likes of alex-Länderbahn und Vogtlandbahn-GmbH or České dráhy to find the best option for your trip from Karlsruhe to Prague.
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Karlsruhe to Prague.
How far in advance should I book train tickets from Karlsruhe to Prague?
Journey information
Overview: Train from Karlsruhe to Prague
Trains from Karlsruhe to Prague run on average 9 times per day, taking around 9h 19m. Cheap train tickets for this journey start at £27 but you can travel from only £25 by coach.
The earliest train runs at 00:19, the last at 23:50. The fastest train covers the 452 km distance in 8h 16m.
Distance 452 km |
Average train duration 9h 19m |
Cheapest ticket price £27 |
Trains per day 9 |
Fastest train 8h 16m |
First train 0:19 |
Last train 23:50 |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Wed |
Best time to book 42 days |
Train companies: Deutsche Bahn, alex-Länderbahn und Vogtlandbahn-GmbH, České dráhy from Karlsruhe to Prague trainsDeutsche Bahn, alex-Länderbahn und Vogtlandbahn-GmbH, České dráhy trains will get you between Karlsruhe and Prague from £25. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
alex-Länderbahn und Vogtlandbahn-GmbH
České dráhy
FAQs: Karlsruhe to Prague train
Find answers to the most common questions about traveling from Karlsruhe to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Karlsruhe and Prague
- Monday: 06:30 - 21:00
- Tuesday: 06:30 - 21:00
- Wednesday: 06:30 - 21:00
- Thursday: 06:30 - 21:00
- Friday: 06:30 - 21:00
- Saturday: 08:00 - 19:00
- Sunday: 09:00 - 20:00
- Vinarte
- Am Tiergarten
- Panorama
- Alter Brauhof
- Hotel Barbarossa
- Hotel Avisa
- Am Tiergarten
- Aparthotel Aijana
- Monday: 08:00 13:30 - 12:30 18:00
- Tuesday: 08:00 13:30 - 12:30 18:00
- Wednesday: 08:00 13:30 - 12:30 18:00
- Thursday: 08:00 13:30 - 12:30 18:00
- Friday: 08:00 13:30 - 12:30 18:00
- Saturday: 09:00 - 13:00
- Hubraum
- Vogel Hausbräu Durlach
- Asia Gourmet
- Borsalino
- Hotel Große Linde
- Zum Erwin
- Der Blaue Reiter
- Beim Schupi
- Rosenstüble 2.0
- Saloniki
- Rote Taube
- Beim Schupi
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, 24 hours a day. Access via Wilsonova Street.
- Restaurant Fantova Kavárna
- Sushi Time
- Outside the main entrance.
- Elevators, ramps.
- CZK 10
- Hotel Esplanade Prague
- Falkensteiner Hotel Maria Prag
- Hotel City Central
- Cost CZK 100
- Located in the main hall
- Located in the main hall
- Avis
- Europcar
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-7 for trains to Germany, Austria, Slovakia, and regional destinations
- Hall 2: Metro connections
- Metro: Line C
- Tram: Lines 5, 9, 26
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available 24/7 with access from Partyzánská street.
- Restaurant Na Kovárně
- Cross Club
- Outside the main entrance.
- Ramps, restrooms.
- CZK 10
- Mama Shelter Prague
- Plaza Alta Hotel
- Hotel Belvedere
- Located in the main hall
- Avis
- Budget
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for trains to Germany, Austria, and regional destinations
- Hall 2: ticket office and waiting area
- Metro: Line C
- Tram: Lines 6, 12, 17
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available nearby with several public parking options.
- Restaurant Kotleta
- Café Imperial
- Outside the main entrance.
- Ramps.
- CZK 10
- Hotel Kings Court
- Grand Hotel Bohemia
- Hotel Paris Prague
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for regional and suburban trains
- Metro: Line B
- Tram: Lines 3, 5, 14, 24
- Bus: Several lines available
Most popular train connections from Karlsruhe
More options for your journey from Karlsruhe to Prague
Here are some other resources that might have the information you need


