The cheapest and fastest trains from Karlsruhe to Brussels
Cheapest price
£91
Average price
£130
Fastest journey
4 h 27 m
Average duration
4 h 50 m
Trains per day
10
Distance
354 km
The best way to find a cheap train ticket from Karlsruhe to Brussels is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Karlsruhe to Brussels will cost around £130 if you buy it on the day, but you can find cheap train tickets today for only £91.
To travel from Karlsruhe to Brussels you need to make at least one change.
12012 · 4347 · Bus 82123 · Bus L529:067h37Karlsruhe Hbf16:43Brussels-Midi£911One-way4 changes
ICE 2556 · ICE 1049 · ICE 167:595h36Karlsruhe Hbf13:35Brussels-Midi£981One-way2 changes
ICE 202 · ICE 168:594h36Karlsruhe Hbf13:35Brussels-Midi£1221One-way1 change
ICE 8 · ICE 168:374h49Karlsruhe Hbf13:26Brussels-North£1251One-way1 change
ICE 202 · ICE 692 · ICE 168:594h27Karlsruhe Hbf13:26Brussels-North£1321One-way2 changes
ICE 202 · ICE 692 · ICE 168:594h27Karlsruhe Hbf13:26Brussels-North£1321One-way2 changes
ICE 202 · ICE 168:594h36Karlsruhe Hbf13:35Brussels-Midi£1221One-way1 change
ICE 8 · ICE 168:374h49Karlsruhe Hbf13:26Brussels-North£1251One-way1 change
ICE 74 · ICE 31410:374h49Karlsruhe Hbf15:26Brussels-North£1471One-way1 change
ICE 2556 · ICE 167:595h27Karlsruhe Hbf13:26Brussels-North£1371One-way1 change
Travel Information
Compare train and coach for Karlsruhe to Brussels
Omio recommends booking the train as it is the most popular option from Karlsruhe to Brussels among Omio's users. If you are prioritising price take the coach with prices starting from £20. For those with little time consider booking a train which can get you there in 3h 37m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a coach costs an average of £20, and a train costs an average of £30.
Distance: 354 km
Compare train with
Most popular Train | Coach |
|---|---|
£97 Average Price | £38 Average Price Cheapest |
4h 7m Average total duration Fastest 3h 37m Onboard + 30m Additional time* | 8h 5m Average total duration 7h 35m Onboard + 30m Additional time* |
0.1 - 0.3kg CO2 emissions Lowest | 0.4 - 0.9kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Karlsruhe to Brussels train times
The table below shows live departures for Karlsruhe to Brussels trains for tomorrow, Friday 10 April. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
ICE 2556 · ICE 314 | On time 5:59 Karlsruhe Hbf | 7h27 | 13:26 Brussels-North | 1 change | |
ICE 2556 · ICE 16 | On time 5:59 Karlsruhe Hbf | 5h27 | 11:26 Brussels-North | 1 change | |
ICE 2556 · ICE 1049 · ICE 16 | On time 5:59 Karlsruhe Hbf | 5h36 | 11:35 Brussels-Midi | 2 changes | |
ICE 8 · ICE 314 | On time 6:37 Karlsruhe Hbf | 6h49 | 13:26 Brussels-North | 1 change | |
ICE 8 · ICE 16 | On time 6:37 Karlsruhe Hbf | 4h49 | 11:26 Brussels-North | 1 change | |
ICE 202 · ICE 692 · ICE 16 | On time 6:59 Karlsruhe Hbf | 4h27 | 11:26 Brussels-North | 2 changes | |
ICE 202 · ICE 16 | On time 6:59 Karlsruhe Hbf | 4h36 | 11:35 Brussels-Midi | 1 change | |
ICE 202 · ICE 692 · ICE 314 | On time 6:59 Karlsruhe Hbf | 6h27 | 13:26 Brussels-North | 2 changes | |
12012 · 4347 · Bus 82123 · Bus L52 | 7:06 Karlsruhe Hbf | 7h37 | 14:43 Brussels-Midi | 4 changes | |
ICE 74 · ICE 314 | 8:37 Karlsruhe Hbf | 4h49 | 13:26 Brussels-North | 1 change | |
Find all the dates and times for this journey
Compare prices and tickets Karlsruhe to Brussels by train or coach
Compare train and coach prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
11 Apr
12 Apr
13 Apr
14 Apr
15 Apr
16 Apr
17 Apr
18 Apr
19 Apr
20 Apr
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24 Apr
Why should you book Karlsruhe to Brussels trains with Omio?
Why book with Omio vs Deutsche Bahn?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are train and bus to ensure you get the best deal for traveling from Karlsruhe to Brussels.
Why book with Omio over Trainline or Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Karlsruhe to Brussels.
Journey information
Overview: Train from Karlsruhe to Brussels
Trains from Karlsruhe to Brussels run on average 5 times per day, taking around 3h 37m. Cheap train tickets for this journey start at £30 but you can travel from only £20 by coach.
The earliest train runs at 00:20, the last at 22:01. The fastest train covers the 354 km distance in 4h 36m.
Distance 354 km |
Average train duration 3h 37m |
Cheapest ticket price £30 |
Trains per day 5 |
Fastest train 4h 36m |
First train 0:20 |
Last train 22:01 |
Train companies: Deutsche Bahn from Karlsruhe to Brussels trainsDeutsche Bahn trains will get you between Karlsruhe and Brussels from £20. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
FAQs: Karlsruhe to Brussels train
Find answers to the most common questions about traveling from Karlsruhe to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Karlsruhe and Brussels
- Monday: 06:30 - 21:00
- Tuesday: 06:30 - 21:00
- Wednesday: 06:30 - 21:00
- Thursday: 06:30 - 21:00
- Friday: 06:30 - 21:00
- Saturday: 08:00 - 19:00
- Sunday: 09:00 - 20:00
- Vinarte
- Am Tiergarten
- Panorama
- Alter Brauhof
- Hotel Barbarossa
- Hotel Avisa
- Am Tiergarten
- Aparthotel Aijana
- Monday: 08:00 13:30 - 12:30 18:00
- Tuesday: 08:00 13:30 - 12:30 18:00
- Wednesday: 08:00 13:30 - 12:30 18:00
- Thursday: 08:00 13:30 - 12:30 18:00
- Friday: 08:00 13:30 - 12:30 18:00
- Saturday: 09:00 - 13:00
- Hubraum
- Vogel Hausbräu Durlach
- Asia Gourmet
- Borsalino
- Hotel Große Linde
- Zum Erwin
- Der Blaue Reiter
- Beim Schupi
- Rosenstüble 2.0
- Saloniki
- Rote Taube
- Beim Schupi
- Mon - Sun: 05:45 - 21:30
- Wi-Fi is available for a fee.
- Baggage storage facility is located across from the Thalys business lounge.
- Pullman Hotel Bar
- Quick Gare du Midi
- Subway
- EXKi Zuid
- Starbucks
- Häagen-Dazs
- Sbarro
- The Coffee Club
- The Belgian Chocolate House
- PAUL
- & many more
- Station has a wide range of facilities for passengers with reduced mobility: elevators and escalators to all platforms, wheelchair lifts and mobile ramps, disabled toilet and parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
- Les Lofts De Styliste
- Park Inn by Radisson Brussels Midi
- Pullman Brussels Centre Midi
- Located in the main concourse and next to the international platforms.
- Mon - Sun: 06:15 - 22:00
- Free Wi-Fi available in Starbucks.
- Luggage lockers are located on Level 0 near Platforms 1 and 2.
- Starbucks
- Brasserie 28 Brewery
- Panos
- Delitraiteur Eat & Go
- Station has a wide range of facilities for passengers with limited mobility: elevators and escalators to platforms, wheelchair lifts and mobile ramps, barrier-free toilets and accessible parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
- Hilton Brussels Grand Palace
- Hotel NH Brussels Carrefour de l'Europe
- Hôtel The Moon
- Mon - Sun: 06:15 - 22:00
- Travel Center / information desk is located on the left side from the main entrance.
- Metro lines: 1, 5
- Train lines: IC, Intercity Direct 9200, RER (S1, S2, S3, S6, S8, S10)
- 6:30 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week. Access is available via Rue du Progrès.
- Chabrol Brasserie
- Winok Café
- Félix Wine Bar
- Outside the main entrance.
- Elevators, ramps.
- €0.50
- Hotel Progress
- Hilton Brussels City
- Hotel Siru
- Located in the main hall
- Avis
- Europcar
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-6 for international and intercity trains
- Hall 2: platform 7-12 for regional and local trains
- Metro: Line 3, Line 4
- Tram: Line 25, Line 55
- Bus: Several lines available
Most popular train connections from Karlsruhe
More options for your journey from Karlsruhe to Brussels
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