The cheapest and fastest trains from Karlsruhe to Brussels
Cheapest price
£88
Average price
£127
Fastest journey
4 h 49 m
Average duration
5 h 2 m
Trains per day
17
Distance
354 km
The best way to find a cheap train ticket from Karlsruhe to Brussels is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Karlsruhe to Brussels will cost around £127 if you buy it on the day, but you can find cheap train tickets today for only £88.
To travel from Karlsruhe to Brussels you need to make at least 2 changes.
ICE 204 · S3 · 4113 · Bus 821196:597h29Karlsruhe Hbf14:28Brussels-Midi£881One-way5 changes
ICE 378 · ICE 9558 · Bus 82117 · Bus 21335:597h29Karlsruhe Hbf13:28Brussels-Midi£881One-way4 changes
ICE 376 · ICE 167:595h36Karlsruhe Hbf13:35Brussels-Midi£1061One-way1 change
ECE 8 · ICE 1012 · S19 · 919908:374h58Karlsruhe Hbf13:35Brussels-Midi£1081One-way4 changes
ICE 376 · ICE 614 · ICE 167:595h27Karlsruhe Hbf13:26Brussels-North£1201One-way2 changes
ECE 8 · ICE 1012 · S19 · S198:374h49Karlsruhe Hbf13:26Brussels-North£1311One-way5 changes
ECE 8 · ICE 1012 · S19 · 919908:374h58Karlsruhe Hbf13:35Brussels-Midi£1081One-way4 changes
ICE 76 · ICE 1014 · S19 · S196:374h58Karlsruhe Hbf11:35Brussels-Midi£1521One-way5 changes
ICE 76 · ICE 1014 · S19 · 920086:374h58Karlsruhe Hbf11:35Brussels-Midi£1351One-way4 changes
ICE 376 · ICE 614 · ICE 167:595h27Karlsruhe Hbf13:26Brussels-North£1201One-way2 changes
Travel Information
Compare coach and train for Karlsruhe to Brussels
Omio recommends booking the train as it is the most popular option from Karlsruhe to Brussels among Omio's users. If you are prioritising price take the coach with prices starting from £19. For those with little time consider booking a train which can get you there in 3h 36m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a coach costs an average of £19, and a train costs an average of £39.
Distance: 354 km
Compare train with
Most popular Train | Coach |
|---|---|
£102 Average Price | £38 Average Price Cheapest |
4h 6m Average total duration Fastest 3h 36m Onboard + 30m Additional time* | 7h 55m Average total duration 7h 25m Onboard + 30m Additional time* |
0.1 - 0.3kg CO2 emissions Lowest | 0.4 - 0.9kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Karlsruhe to Brussels train times
The table below shows live departures for Karlsruhe to Brussels trains for tomorrow, Friday 10 July. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
ICE 378 · ICE 616 · ICE 316 | On time 5:59 Karlsruhe Hbf | 5h36 | 11:35 Brussels-Midi | 2 changes | |
ICE 378 · ICE 616 · S19 · 92008 | On time 5:59 Karlsruhe Hbf | 5h36 | 11:35 Brussels-Midi | 4 changes | |
ICE 378 · ICE 316 | On time 5:59 Karlsruhe Hbf | 5h36 | 11:35 Brussels-Midi | 1 change | |
ICE 378 · ICE 9558 · Bus 82117 · Bus 2133 | On time 5:59 Karlsruhe Hbf | 7h29 | 13:28 Brussels-Midi | 4 changes | |
ICE 76 · ICE 1014 · S19 · S19 | On time 6:37 Karlsruhe Hbf | 4h58 | 11:35 Brussels-Midi | 5 changes | |
ICE 76 · ICE 1014 · S19 · 92008 | On time 6:37 Karlsruhe Hbf | 4h58 | 11:35 Brussels-Midi | 4 changes | |
ICE 204 · S3 · 4113 · Bus 82119 | On time 6:59 Karlsruhe Hbf | 7h29 | 14:28 Brussels-Midi | 5 changes | |
ICE 376 · ICE 314 | On time 7:59 Karlsruhe Hbf | 7h27 | 15:26 Brussels-North | 1 change | |
ICE 376 · ICE 614 · ICE 16 | On time 7:59 Karlsruhe Hbf | 5h27 | 13:26 Brussels-North | 2 changes | |
ICE 376 · ICE 1020 · ICE 314 | On time 7:59 Karlsruhe Hbf | 7h27 | 15:26 Brussels-North | 2 changes | |
ICE 376 · ICE 16 | On time 7:59 Karlsruhe Hbf | 5h36 | 13:35 Brussels-Midi | 1 change | |
ECE 8 · ICE 1012 · S19 · 91990 | On time 8:37 Karlsruhe Hbf | 4h58 | 13:35 Brussels-Midi | 4 changes | |
ECE 8 · ICE 314 | On time 8:37 Karlsruhe Hbf | 6h49 | 15:26 Brussels-North | 1 change | |
ECE 8 · ICE 1012 · S19 · S19 | On time 8:37 Karlsruhe Hbf | 4h49 | 13:26 Brussels-North | 5 changes | |
ECE 8 · ICE 1012 · ICE 1020 · ICE 314 | On time 8:37 Karlsruhe Hbf | 6h58 | 15:35 Brussels-Midi | 3 changes | |
ICE 1670 · ICE 314 | On time 8:41 Karlsruhe Hbf | 6h45 | 15:26 Brussels-North | 1 change | |
ICE 202 · ICE 692 · ICE 314 | On time 8:59 Karlsruhe Hbf | 6h27 | 15:26 Brussels-North | 2 changes | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Karlsruhe to Brussels by coach or train
Compare coach and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
10 Jul
11 Jul
12 Jul
13 Jul
14 Jul
15 Jul
16 Jul
Why should you book Karlsruhe to Brussels trains with Omio?
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of Deutsche Bahn Intercity (DB IC) or Deutsche Bahn Regio (DB Regional) to find the best option for your trip from Karlsruhe to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are bus and train to ensure you get the best deal for traveling from Karlsruhe to Brussels.
Why book with Omio over Trainline or Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Karlsruhe to Brussels.
Journey information
Overview: Train from Karlsruhe to Brussels
Trains from Karlsruhe to Brussels run on average 5 times per day, taking around 3h 36m. Cheap train tickets for this journey start at £39 but you can travel from only £19 by coach.
The earliest train runs at 00:20, the last at 22:01. The fastest train covers the 354 km distance in 4h 36m.
Distance 354 km |
Average train duration 3h 36m |
Cheapest ticket price £39 |
Trains per day 5 |
Fastest train 4h 36m |
First train 0:20 |
Last train 22:01 |
Cheapest Month Mar |
Cheapest Day Sat |
High Season Jul - Sept |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Tue |
Best time to book 49 days |
Train companies: Deutsche Bahn, Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional) from Karlsruhe to Brussels trainsDeutsche Bahn, Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional) trains will get you between Karlsruhe and Brussels from £19. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Deutsche Bahn Intercity (DB IC)
Deutsche Bahn Regio (DB Regional)
FAQs: Karlsruhe to Brussels train
Find answers to the most common questions about traveling from Karlsruhe to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Karlsruhe and Brussels
Most Karlsruhe to Brussels trains use the Karlsruhe Hbf to Bruxelles-Midi station pair, with some services arriving at Bruxelles-Central. Use this guide to compare Karlsruhe and Brussels train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Which Karlsruhe station do trains to Brussels leave from?
Getting to Karlsruhe Hbf from Karlsruhe city centre
Karlsruhe Hbf is 1 km from Karlsruhe city centre. Public transport options include:
Karlsruhe Hbf train station facilities and services
Karlsruhe Hbf has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental and Information Desk.
Food and drink
Food options include: Vinarte, Am Tiergarten, Panorama, Alter Brauhof
Wi-Fi and ATMs
Wi-Fi is available at Karlsruhe Hbf. ATMs are available at Karlsruhe Hbf.
Tickets and information
Ticket office support is available at Karlsruhe Hbf. Information desks are available at Karlsruhe Hbf.
Luggage and lost property
Luggage storage is available at Karlsruhe Hbf. Lost and found is available at the station.
Parking, taxis and toilets
Available at Karlsruhe Hbf: Parking, Taxis, WC.
Bike and car services
Available at Karlsruhe Hbf: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Karlsruhe Hbf.
Shops, hotels and contact
Nearby hotels include Hotel Barbarossa, Hotel Avisa, Am Tiergarten, Aparthotel Aijana.
Getting to Karlsruhe-Durlach from Karlsruhe city centre
Karlsruhe-Durlach is 5 km from Karlsruhe city centre. Public transport options include:
Karlsruhe-Durlach train station facilities and services
Karlsruhe-Durlach has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental and Information Desk.
Food and drink
Food options include: Hubraum, Vogel Hausbräu Durlach, Asia Gourmet, Borsalino
Wi-Fi and ATMs
Wi-Fi is available at Karlsruhe-Durlach. ATMs are available at Karlsruhe-Durlach.
Tickets and information
Ticket office support is available at Karlsruhe-Durlach. Information desks are available at Karlsruhe-Durlach.
Luggage and lost property
Luggage storage is available at Karlsruhe-Durlach. Lost and found is available at the station.
Parking, taxis and toilets
Available at Karlsruhe-Durlach: Parking, Taxis, WC.
Bike and car services
Available at Karlsruhe-Durlach: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Karlsruhe-Durlach.
Shops, hotels and contact
Nearby hotels include Hotel Große Linde, Zum Erwin, Der Blaue Reiter.
Getting to Karlsruhe West from Karlsruhe city centre
Karlsruhe West is 1 km from Karlsruhe city centre. Public transport options include:
Karlsruhe West train station facilities and services
Karlsruhe West has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental and Information Desk.
Food and drink
Food options include: Beim Schupi, Rosenstüble 2.0, Saloniki, Rote Taube
Wi-Fi and ATMs
Wi-Fi is available at Karlsruhe West. ATMs are available at Karlsruhe West.
Tickets and information
Ticket office support is available at Karlsruhe West. Information desks are available at Karlsruhe West.
Luggage and lost property
Luggage storage is available at Karlsruhe West. Lost and found is available at the station.
Parking, taxis and toilets
Available at Karlsruhe West: Parking, Taxis, WC.
Bike and car services
Available at Karlsruhe West: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Karlsruhe West.
Shops, hotels and contact
Nearby hotels include Beim Schupi.
Which Brussels station do trains from Karlsruhe arrive at?
Getting to Bruxelles-Midi from Brussels city centre
Bruxelles-Midi train station facilities and services
Bruxelles-Midi has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental and Information Desk.
Food and drink
Food options include: Pullman Hotel Bar, Quick Gare du Midi, Subway, EXKi Zuid, Starbucks, Häagen-Dazs, Sbarro, The Coffee Club, The Belgian Chocolate House, PAUL, & many more
Wi-Fi and ATMs
Wi-Fi is available for a fee. ATMs are available at Bruxelles-Midi.
Tickets and information
Ticket office support is available at Bruxelles-Midi. Information desks are located in the main concourse and next to the international platforms.
Luggage and lost property
Luggage storage is baggage storage facility is located across from the Thalys business lounge.
Parking, taxis and toilets
Available at Bruxelles-Midi: Parking, Taxis, WC.
Bike and car services
Available at Bruxelles-Midi: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Bruxelles-Midi: Station has a wide range of facilities for passengers with reduced mobility: elevators and escalators to all platforms, wheelchair lifts and mobile ramps, disabled toilet and parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
Shops, hotels and contact
Nearby hotels include Les Lofts De Styliste, Park Inn by Radisson Brussels Midi, Pullman Brussels Centre Midi.
Getting to Bruxelles-Central from Brussels city centre
Bruxelles-Central train station facilities and services
Bruxelles-Central has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental and Information Desk.
Food and drink
Food options include: Starbucks, Brasserie 28 Brewery, Panos, Delitraiteur Eat & Go
Wi-Fi and ATMs
Free Wi-Fi available in Starbucks. ATMs are aTM machine is downstairs from the main entrance on the right side.
Tickets and information
The ticket office is open Mon - Sun: 06:15 - 22:00. Information desks are travel Center / information desk is located on the left side from the main entrance.
Luggage and lost property
Luggage storage is luggage lockers are located on Level 0 near Platforms 1 and 2.
Parking, taxis and toilets
Available at Bruxelles-Central: Parking, Taxis, WC.
Bike and car services
Available at Bruxelles-Central: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Bruxelles-Central: Station has a wide range of facilities for passengers with limited mobility: elevators and escalators to platforms, wheelchair lifts and mobile ramps, barrier-free toilets and accessible parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
Shops, hotels and contact
Nearby hotels include Hilton Brussels Grand Palace, Hotel NH Brussels Carrefour de l'Europe, Hôtel The Moon.
Getting to Brussels-Nord from Brussels city centre
Brussels-Nord is 1 km from Brussels city centre. Public transport options include:
Brussels-Nord train station facilities and services
Brussels-Nord has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk and Luggage Carts.
Food and drink
Food options include: Chabrol Brasserie, Winok Café, Félix Wine Bar
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Brussels-Nord. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Brussels-Nord. Lost and found is available at the station.
Parking, taxis and toilets
Available at Brussels-Nord: Parking, Taxis, WC.
Bike and car services
Available at Brussels-Nord: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Brussels-Nord: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Hotel Progress, Hilton Brussels City, Hotel Siru.
Most popular train connections from Karlsruhe
More options for your journey from Karlsruhe to Brussels
Here are some other resources that might have the information you need

