Madrid to Palermo bus with FlixBus

Tue 20 Oct
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FlixBus
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National Express
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Avanza
2,000+ travel companies
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The cheapest and fastest coaches from Madrid to Palermo

Showing times, prices and bookable tickets for 20 Oct

Cheapest price on 20 Oct

£137

Average ticket price on 20 Oct

£169

Fastest journey on 20 Oct

1 d 20 h 10 m

Average journey duration on 20 Oct

2 d 6 h 32 m

Buses on 20 Oct

3

Distance

1489 km

Cheap tickets

The best way to find a cheap coach ticket from Madrid to Palermo is to book your journey as far in advance as possible and to avoid travelling at rush hour.

The average ticket from Madrid to Palermo will cost around £169 if you buy it on the day, but you can find cheap coach tickets today for only £137.

Fast coaches

To travel from Madrid to Palermo you need to make at least 2 changes.

  • FlixBusFlixBus · FlixBus · FlixBus
    19:0544h10
    Madrid, Estación Sur de Autobuses
    15:15Palermo, Via Tommaso Fazello (Terminal Bus)
    £1371One-way
    2 changes
  • FlixBusFlixBus · FlixBus · FlixBus
    22:3560h25
    Madrid, Estación Sur de Autobuses
    11:00Palermo, Via Tommaso Fazello (Terminal Bus)
    £1841One-way
    2 changes
  • FlixBusFlixBus · FlixBus · FlixBus · FlixBus
    23:5959h01
    Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid)
    11:00Palermo, Via Tommaso Fazello (Terminal Bus)
    £1861One-way
    3 changes

Journey information

Overview: Bus from Madrid to Palermo

SpainSpain
ItalyItaly
Icon of bus

Buses from Madrid to Palermo run on average 3 times per day, taking around 48h 39m. Cheap bus tickets for this journey start at £110 but you can travel from only £22 by flight.

The earliest coach runs at 00:40, the last at 23:50. The fastest coach covers the 1489 km distance in 40h 5m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from £22
Distance
1489 km
Average bus duration
48h 39m
Cheapest ticket price
£110
Buses per day
3
Fastest bus
40h 5m
First bus
0:40
Last bus
23:50
Cheapest Month
Jun
Cheapest Day
Sun
High Season
Jul - Sept
Low Season
Jan - Mar
Busiest Day
Wed
Least Busy Day
Thu
Best time to book
84 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from £22

Live departures

Madrid to Palermo bus times

The table below shows live departures for Madrid to Palermo coaches for tomorrow, Tuesday 20 October. You can also manually refresh the results below to see updated coach journeys.

Last updated at
ProviderDepartsDurationArrivesChanges
Tickets
FlixBusFlixBus · FlixBus · FlixBus19:05 Madrid, Estación Sur de Autobuses
44h10
15:15 Palermo, Via Tommaso Fazello (Terminal Bus)2 changes
FlixBusFlixBus · FlixBus · FlixBus22:35 Madrid, Estación Sur de Autobuses
60h25
11:00 Palermo, Via Tommaso Fazello (Terminal Bus)2 changes
FlixBusFlixBus · FlixBus · FlixBus · FlixBus23:59 Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid)
59h01
11:00 Palermo, Via Tommaso Fazello (Terminal Bus)3 changes

This is the last bus of the day.

Find all the dates and times for this journey

Why should you book Madrid to Palermo coaches with Omio?

FlixBus operates all coaches services from Madrid to Palermo.
Omio is an official ticket reseller for all your travel options from Madrid to Palermo.

Why book with Omio vs FlixBus?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Madrid to Palermo.

Why book with Omio over Wanderu or Trainline?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Madrid to Palermo.

Bus providers: FlixBus from Madrid to PalermoYou can travel by bus between Madrid to Palermo with FlixBus for as low as £22. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
40h 5m
Cheapest FlixBus Price
£110
FlixBus frequency
3 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Complete guide to Palermo

Things to do in Palermo

Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.

  • Must visit

Galleria Regionale della Sicilia - Palazzo Abatellis

Important Sicilian art museum in Palazzo Abatellis, with medieval and Renaissance works including Antonello da Messina’s celebrated portrait.

  • Recommended

Museo Archeologico Regionale Antonino Salinas

Archaeological museum with Greek, Roman and Etruscan finds, coins and sculpture. A strong choice for understanding Sicily’s ancient past.

  • Recommended

GAM - Galleria d'Arte Moderna

Modern and contemporary art museum in a restored monastery complex. Visit for Italian art, changing exhibitions and a central historic setting.

Euro (€)

Moderate for Italy: street food and buses are cheap, while central hotels and seafood restaurants cost more in peak season.

Average meal costs

Budget
€8-12 for street food or a simple meal.
Mid-range
€20-35 per person for a restaurant meal.
Fine dining
€60+ per person for upscale dining.
Coffee
€1.50-3 for espresso or cappuccino.

Tipping culture

Service is often included or modest. Round up or leave €1-2 in cafés, 5-10% for very good restaurant service, and round up taxi fares.

Best day trips from Palermo by bus

The most popular day trips by bus from Palermo are Cefalù, Monreale, Trapani, Erice and Agrigento. Find out what you can do in these day trip destinations and how to book your bus from Palermo on Omio.

A view of Cefalù

Day trip from Palermo to Cefalù by bus

Why visit Cefalù for the day?

Cefalù is a historic seaside town on Sicily’s north coast, known for its Norman cathedral, sandy beach and medieval lanes. La Rocca towers above the old town, giving the place a dramatic setting and an easy-going Sicilian character.

How to get from Palermo to Cefalù by bus?

The earliest coach runs at 00:20, the last at 22:37.

A view of Trapani

Day trip from Palermo to Trapani by bus

Why visit Trapani for the day?

Trapani is a historic Sicilian port known for its seafront, salt pans and fishing heritage. Baroque churches, narrow streets and views towards the Egadi Islands give it a relaxed maritime character.

How to get from Palermo to Trapani by bus?

There are 2 coaches per day. The earliest coach runs at 00:25, the last at 23:58. The fastest coach covers the 75 km distance in 1h 30m.

A view of Erice

Day trip from Palermo to Erice by bus

Why visit Erice for the day?

Erice is a medieval hill town in western Sicily, known for its stone streets and sweeping views over Trapani. Its ancient religious sites, quiet atmosphere and almond pastries give it a distinctly historic character.

How to get from Palermo to Erice by bus?

There are 2 coaches per day. The earliest coach runs at 04:40, the last at 23:50. The fastest coach covers the 68 km distance in 1h 30m.

A view of Agrigento

Day trip from Palermo to Agrigento by bus

Why visit Agrigento for the day?

Agrigento is best known for the Valle dei Templi, one of Sicily’s great archaeological landscapes. Above the coast, its old town combines steep streets, churches and a distinctly Sicilian atmosphere.

How to get from Palermo to Agrigento by bus?

The earliest coach runs at 05:55, the last at 15:25. The fastest coach covers the 91 km distance in 4h 49m.

FAQs: Madrid to Palermo coach

Find answers to the most common questions about traveling from Madrid to Palermo by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

FAQs
Cheap coach tickets from Madrid to Palermo can start from as little as £110 when you book in advance. The average coach ticket price for Madrid to Palermo is £190; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by coach from Madrid to Palermo is 40h 5m to travel the 1489 km long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest coach from Madrid to Palermo leaves at 0:40. Plan your trip with the Journey Planner from Omio.
The latest coach from Madrid to Palermo leaves at 23:50.
There are 3 coaches a day from Madrid to Palermo which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer coaches.
When taking a coach from Madrid to Palermo, you can count on FlixBus for the best way to get you to Palermo. You can also check all possible coach companies who offer a service between Madrid and Palermo and compare the amenities they offer before buying a coach ticket.
It's helpful to compare your options as there are 3 ways to travel between Madrid and Palermo including taking a train, coach and flight.
Yes, there are bathrooms on board the coach from Madrid to Palermo for coach company FlixBus.
Yes, the following accessibility options are available when taking the coach from Madrid to Palermo:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Whether you can cancel your coach ticket from Madrid to Palermo depends on the coach companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the coach with coach company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the coach from Madrid to Palermo.
Yes, the following luggage options are included when booking a coach ticket from Madrid to Palermo:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a coach ticket from Madrid to Palermo:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the coach from Madrid to Palermo. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the coach from Madrid to Palermo with the following coach company: FlixBus
Yes, there are USB plugs on board the coach from Madrid to Palermo with the following coach company: FlixBus.
Yes, there is Wifi on board the coach from Madrid to Palermo with the following coach company: FlixBus.

popular bus stations

Important Stations and Airports in Madrid and Palermo

Most Madrid to Palermo buses use the Madrid, Estación Sur de Autobuses to station pair. Use this guide to compare Madrid and Palermo bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Madrid
Arrival bus stations in Palermo

Which Madrid station do buses to Palermo leave from?

Buses from Madrid to Palermo leave from Madrid, Estación Sur de Autobuses. The station is 3 km from Madrid city centre at Calle de Mendez Alvaro, 83, 28045 Madrid, Spain.
Madrid, Estación Sur de AutobusesCalle de Mendez Alvaro, 83, 28045 Madrid, SpainWifiParkingDiningATMTaxisAccessibilityWCTicket Office
City-centre transport

Getting to Madrid, Estación Sur de Autobuses from Madrid city centre

Madrid, Estación Sur de Autobuses is 3 km from Madrid city centre. Public transport options include:

TrainC5, C10, C7 · 2m · £1 · every ~23 min
C10, C7 · 8m · £1 · every ~8 min
C3, C4, C4a, C4b · 11m · £1 · every ~15 min
BusN11 · 16m · £1 · every ~11 min
N13 · 18m · £1 · every ~15 min
148 · 45m · £4 · every ~30 min
Subway6 · 24m · £2 · every ~48 min

Madrid, Estación Sur de Autobuses bus station facilities and services

Madrid, Estación Sur de Autobuses has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.

Food and drink

Food options include: Cafetería de la estación (in the station), Restaurante El Brillante (0.5 km), La Taberna de Domínguez (0.7 km).

Wi-Fi and ATMs

Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.

Tickets and information

Ticket office support is available at Madrid, Estación Sur de Autobuses.

Parking, taxis and toilets

Available at Madrid, Estación Sur de Autobuses: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Madrid, Estación Sur de Autobuses: Elevators, ramps.

Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid)Av. de la Hispanidad, s/n, 28042 Madrid, SpainDiningATMAccessibilityWCShowerTicket Office
City-centre transport

Getting to Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) from Madrid city centre

Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) is 12 km from Madrid city centre. Public transport options include:

Bus203, N27 · 1h 2m · £8 · every ~45 min

Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) bus station facilities and services

Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) has practical services for this route, including Dining, ATM, Accessibility, WC, Shower and Ticket Office.

Food and drink

Food options include: Rodilla, Mahoudrid

Wi-Fi and ATMs

ATMs are aTMs located throughout T4, major cards accepted .

Tickets and information

Ticket office support is available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid).

Parking, taxis and toilets

Available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): WC.

Accessibility

Accessibility facilities are available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): Step-free access, elevators, accessible toilets.

More options for your journey from Madrid to Palermo

Here are some other resources that might have the information you need

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