- Must visit
Galleria Regionale della Sicilia - Palazzo Abatellis
Important Sicilian art museum in Palazzo Abatellis, with medieval and Renaissance works including Antonello da Messina’s celebrated portrait.
Cheapest price on 20 Oct
£137
Average ticket price on 20 Oct
£169
Fastest journey on 20 Oct
1 d 20 h 10 m
Average journey duration on 20 Oct
2 d 6 h 32 m
Buses on 20 Oct
3
Distance
1489 km
The best way to find a cheap coach ticket from Madrid to Palermo is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Madrid to Palermo will cost around £169 if you buy it on the day, but you can find cheap coach tickets today for only £137.
To travel from Madrid to Palermo you need to make at least 2 changes.
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBusBuses from Madrid to Palermo run on average 3 times per day, taking around 48h 39m. Cheap bus tickets for this journey start at £110 but you can travel from only £22 by flight.
The earliest coach runs at 00:40, the last at 23:50. The fastest coach covers the 1489 km distance in 40h 5m.
Distance 1489 km |
Average bus duration 48h 39m |
Cheapest ticket price £110 |
Buses per day 3 |
Fastest bus 40h 5m |
First bus 0:40 |
Last bus 23:50 |
Cheapest Month Jun |
Cheapest Day Sun |
High Season Jul - Sept |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Thu |
Best time to book 84 days |
The table below shows live departures for Madrid to Palermo coaches for tomorrow, Tuesday 20 October. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 19:05 Madrid, Estación Sur de Autobuses | 44h10 | 15:15 Palermo, Via Tommaso Fazello (Terminal Bus) | 2 changes | |
FlixBus · FlixBus · FlixBus | 22:35 Madrid, Estación Sur de Autobuses | 60h25 | 11:00 Palermo, Via Tommaso Fazello (Terminal Bus) | 2 changes | |
FlixBus · FlixBus · FlixBus · FlixBus | 23:59 Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 59h01 | 11:00 Palermo, Via Tommaso Fazello (Terminal Bus) | 3 changes | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
Important Sicilian art museum in Palazzo Abatellis, with medieval and Renaissance works including Antonello da Messina’s celebrated portrait.
Archaeological museum with Greek, Roman and Etruscan finds, coins and sculpture. A strong choice for understanding Sicily’s ancient past.
Modern and contemporary art museum in a restored monastery complex. Visit for Italian art, changing exhibitions and a central historic setting.
Monumental square at the junction of Palermo’s historic main streets. A classic meeting point with theatrical Baroque façades and constant street life.
Elegant square beside Teatro Massimo, popular for strolling and people-watching. A useful base for exploring central Palermo on foot.
Historic market district with layered architecture, lively lanes and everyday city life. Best for atmosphere, street scenes and local character.
Fried rice balls filled with ragù, peas and cheese. A Sicilian street-food classic, especially beloved in Palermo for its hearty, portable character.
Soft sesame-topped roll stuffed with spleen and lung, often with ricotta or caciocavallo. A distinctive Palermo sandwich with deep working-class roots.
Pasta with sardines, wild fennel, raisins and pine nuts. It captures Palermo’s Arab-Norman culinary heritage through sweet-savoury flavours.
Traditional restaurant serving Sicilian seafood, pasta and Palermo classics in an elegant but relaxed historic-centre atmosphere.
Historic market stall famed for pane ca meusa and other Palermo street-food staples in a lively, no-frills setting.
Long-established informal spot known for arancine, panelle and other classic rosticceria specialities popular with locals.
Moderate for Italy: street food and buses are cheap, while central hotels and seafood restaurants cost more in peak season.
Service is often included or modest. Round up or leave €1-2 in cafés, 5-10% for very good restaurant service, and round up taxi fares.
The most popular day trips by bus from Palermo are Cefalù, Monreale, Trapani, Erice and Agrigento. Find out what you can do in these day trip destinations and how to book your bus from Palermo on Omio.

Cefalù is a historic seaside town on Sicily’s north coast, known for its Norman cathedral, sandy beach and medieval lanes. La Rocca towers above the old town, giving the place a dramatic setting and an easy-going Sicilian character.
The earliest coach runs at 00:20, the last at 22:37.


Trapani is a historic Sicilian port known for its seafront, salt pans and fishing heritage. Baroque churches, narrow streets and views towards the Egadi Islands give it a relaxed maritime character.
There are 2 coaches per day. The earliest coach runs at 00:25, the last at 23:58. The fastest coach covers the 75 km distance in 1h 30m.

Erice is a medieval hill town in western Sicily, known for its stone streets and sweeping views over Trapani. Its ancient religious sites, quiet atmosphere and almond pastries give it a distinctly historic character.
There are 2 coaches per day. The earliest coach runs at 04:40, the last at 23:50. The fastest coach covers the 68 km distance in 1h 30m.

Agrigento is best known for the Valle dei Templi, one of Sicily’s great archaeological landscapes. Above the coast, its old town combines steep streets, churches and a distinctly Sicilian atmosphere.
The earliest coach runs at 05:55, the last at 15:25. The fastest coach covers the 91 km distance in 4h 49m.
Find answers to the most common questions about traveling from Madrid to Palermo by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

Most Madrid to Palermo buses use the Madrid, Estación Sur de Autobuses to station pair. Use this guide to compare Madrid and Palermo bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Madrid, Estación Sur de Autobuses is 3 km from Madrid city centre. Public transport options include:
Madrid, Estación Sur de Autobuses has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food options include: Cafetería de la estación (in the station), Restaurante El Brillante (0.5 km), La Taberna de Domínguez (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.
Ticket office support is available at Madrid, Estación Sur de Autobuses.
Available at Madrid, Estación Sur de Autobuses: Parking, Taxis, WC.
Accessibility facilities are available at Madrid, Estación Sur de Autobuses: Elevators, ramps.
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) is 12 km from Madrid city centre. Public transport options include:
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) has practical services for this route, including Dining, ATM, Accessibility, WC, Shower and Ticket Office.
Food options include: Rodilla, Mahoudrid
ATMs are aTMs located throughout T4, major cards accepted .
Ticket office support is available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid).
Available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): WC.
Accessibility facilities are available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): Step-free access, elevators, accessible toilets.
Here are some other resources that might have the information you need