The cheapest and fastest trains from Venice Mestre to Florence Santa Maria Novella
Cheapest price
£20
Average price
£43
Fastest journey
1 h 59 m
Average duration
2 h
Trains per day
42
Distance
205 km
The best way to find a cheap train ticket from Venice Mestre to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Venice Mestre to Florence Santa Maria Novella will cost around £43 if you buy it on the day, but you can find cheap train tickets today for only £20.
Of the 42 trains that leave Venice Mestre for Florence Santa Maria Novella every day 27 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct trains cover the 205 km distance in an average of 2 h but if you time it right, some trains will get you there in just 1 h 59 m .
The slowest trains will take 2 h 1 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Regionale Veloce 3979 · Regionale 17839 · Tuscany Line 18527
Regionale Veloce 3965 · Regionale 17819 · Regionale 34097
Regionale Veloce 3983 · Regionale TTPER 17847 · TUSCANY LINE 18531
Regionale Veloce 3971 · Regionale TTPER 17827 · Tuscany Line 18517
Regionale Veloce 3975 · Regionale 17833 · Tuscany Line 18521
FRECCIAROSSA 1000 9409
8907
FRECCIAROSSA 1000 9437
FRECCIAROSSA 1000 9433
FRECCIAROSSA 1000 9425Travel Information
Compare train and coach for Venice Mestre to Florence Santa Maria Novella
Omio recommends booking the train as it is the most popular option from Venice Mestre to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the coach with prices starting from £7. For those with little time consider booking a train which can get you there in 3h 26m. The ticket price range depends on the travel mode: a coach costs an average of £7, and a train costs an average of £19.
Distance: 205 km
Compare train with
Most popular Train | Coach |
|---|---|
£34 Average Price | £17 Average Price Cheapest |
3h 56m Average total duration Fastest 3h 26m Onboard + 30m Additional time* | 4h 27m Average total duration 3h 57m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Venice Mestre to Florence Santa Maria Novella train times
The table below shows live departures for Venice Mestre to Florence Santa Maria Novella trains for today, Friday 27 February. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
FRECCIAROSSA 1000 9431 | 15:38 Venice Mestre | 2h01 | 17:39 Florence Santa Maria Novella | 0 changesdirect | |
Regionale Veloce 3983 · Regionale TTPER 17847 · TUSCANY LINE 18531 | 15:53 Venice Mestre | 3h59 | 19:52 Florence Santa Maria Novella | 2 changes | |
8925 | On time 16:17 Venice Mestre | 2h03 | 18:20 Florence Santa Maria Novella | 0 changesdirect | |
FRECCIAROSSA 1000 9433 | 16:38 Venice Mestre | 2h01 | 18:39 Florence Santa Maria Novella | 0 changesdirect | |
Regionale Veloce 3985 · Regionale 17851 | 16:53 Venice Mestre | 4h17 | 21:10 Florence Santa Maria Novella | 1 change | |
8927 | On time 17:17 Venice Mestre | 2h03 | 19:20 Florence Santa Maria Novella | 0 changesdirect | |
FRECCIAROSSA 9435 | 17:38 Venice Mestre | 2h01 | 19:39 Florence Santa Maria Novella | 0 changesdirect | |
FRECCIAROSSA 1000 9437 | 18:38 Venice Mestre | 2h01 | 20:39 Florence Santa Maria Novella | 0 changesdirect | |
Regionale Veloce 3989 · Regionale 17853 · Regionale 34127 | 18:53 Venice Mestre | 3h57 | 22:50 Florence Santa Maria Novella | 2 changes | |
| Saturday 28 February | |||||
FRECCIAROSSA 9401 | 04:38 Venice Mestre | 2h01 | 06:39 Florence Santa Maria Novella | 0 changesdirect | |
Regionale Veloce 3961 · Regionale 17813 · Regionale 34091 | 04:53 Venice Mestre | 3h59 | 08:52 Florence Santa Maria Novella | 2 changes | |
FRECCIAROSSA 9403 | 05:38 Venice Mestre | 2h01 | 07:39 Florence Santa Maria Novella | 0 changesdirect | |
Regionale Veloce 3963 · Regionale 17817 · TUSCANY LINE 18509 | 05:53 Venice Mestre | 3h59 | 09:52 Florence Santa Maria Novella | 2 changes | |
8903 | On time 06:17 Venice Mestre | 2h03 | 08:20 Florence Santa Maria Novella | 0 changesdirect | |
FRECCIAROSSA 9405 | 06:38 Venice Mestre | 2h01 | 08:39 Florence Santa Maria Novella | 0 changesdirect | |
Regionale Veloce 3965 · Regionale 17819 · Regionale 34097 | 06:53 Venice Mestre | 3h59 | 10:52 Florence Santa Maria Novella | 2 changes | |
8905 | On time 07:17 Venice Mestre | 2h03 | 09:20 Florence Santa Maria Novella | 0 changesdirect | |
FRECCIAROSSA 1000 9409 | 07:40 Venice Mestre | 1h59 | 09:39 Florence Santa Maria Novella | 0 changesdirect | |
8907 | 08:20 Venice Mestre | 2h00 | 10:20 Florence Santa Maria Novella | 0 changesdirect | |
FRECCIAROSSA 1000 9411 | 08:38 Venice Mestre | 2h01 | 10:39 Florence Santa Maria Novella | 0 changesdirect | |
Regionale Veloce 3997 · Regionale 17825 · Regionale 34101 | 08:53 Venice Mestre | 3h59 | 12:52 Florence Santa Maria Novella | 2 changes | |
8902 | On time 09:17 Venice Mestre | 2h03 | 11:20 Florence Santa Maria Novella | 0 changesdirect | |
FRECCIAROSSA 1000 9413 | 09:38 Venice Mestre | 2h01 | 11:39 Florence Santa Maria Novella | 0 changesdirect | |
Regionale Veloce 3971 · Regionale TTPER 17827 · Tuscany Line 18517 | 09:53 Venice Mestre | 3h59 | 13:52 Florence Santa Maria Novella | 2 changes | |
8911 | On time 10:17 Venice Mestre | 2h03 | 12:20 Florence Santa Maria Novella | 0 changesdirect | |
FRECCIAROSSA 1000 9415 | 10:38 Venice Mestre | 2h01 | 12:39 Florence Santa Maria Novella | 0 changesdirect | |
Regionale Veloce 3973 · Regionale 17831 · Regionale 34107 | 10:53 Venice Mestre | 4h02 | 14:55 Florence Santa Maria Novella | 2 changes | |
8929 | 11:17 Venice Mestre | 2h03 | 13:20 Florence Santa Maria Novella | 0 changesdirect | |
FRECCIAROSSA 1000 8419 | 11:38 Venice Mestre | 2h01 | 13:39 Florence Santa Maria Novella | 0 changesdirect | |
Regionale Veloce 3975 · Regionale 17833 · Tuscany Line 18521 | 11:53 Venice Mestre | 3h59 | 15:52 Florence Santa Maria Novella | 2 changes | |
8913 | 12:17 Venice Mestre | 2h03 | 14:20 Florence Santa Maria Novella | 0 changesdirect | |
FRECCIAROSSA 9421 | 12:38 Venice Mestre | 2h01 | 14:39 Florence Santa Maria Novella | 0 changesdirect | |
Regionale Veloce 3977 · Regionale 17837 · Tuscany Line 18525 | 12:53 Venice Mestre | 3h59 | 16:52 Florence Santa Maria Novella | 2 changes | |
8915 | On time 13:17 Venice Mestre | 2h03 | 15:20 Florence Santa Maria Novella | 0 changesdirect | |
FRECCIAROSSA 1000 9425 | 13:38 Venice Mestre | 2h01 | 15:39 Florence Santa Maria Novella | 0 changesdirect | |
Regionale Veloce 3979 · Regionale 17839 · Tuscany Line 18527 | 13:53 Venice Mestre | 3h59 | 17:52 Florence Santa Maria Novella | 2 changes | |
8919 | On time 14:17 Venice Mestre | 2h03 | 16:20 Florence Santa Maria Novella | 0 changesdirect | |
Intercity 594+ Regionale 18312 | 14:34 Venice Mestre | 3h09 | 17:43 Florence Santa Maria Novella | 1 change | |
FRECCIAROSSA 1000 9427 | 14:38 Venice Mestre | 2h01 | 16:39 Florence Santa Maria Novella | 0 changesdirect | |
Regionale Veloce 3981 · Regionale 17843 · TUSCANY LINE 18529 | 14:53 Venice Mestre | 3h59 | 18:52 Florence Santa Maria Novella | 2 changes | |
8923 | On time 15:17 Venice Mestre | 2h03 | 17:20 Florence Santa Maria Novella | 0 changesdirect | |
This is the last train of the day. | |||||
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Compare prices and tickets Venice Mestre to Florence Santa Maria Novella by train or coach
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Why should you book Venice Mestre to Florence Santa Maria Novella trains with Omio?
Why book with Omio vs Italo?
- Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Frecciarossa, Regionale, Intercity or Intercity Notte to find the best option for your trip from Venice Mestre to Florence Santa Maria Novella.
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- Compare all your options: Omio allows you to compare Italo with all available travel options, which are train and bus to ensure you get the best deal for traveling from Venice Mestre to Florence Santa Maria Novella.
Journey information
Overview: Train from Venice Mestre to Florence Santa Maria Novella
Trains from Venice Mestre to Florence Santa Maria Novella run on average 24 times per day, taking around 3h 26m. Cheap train tickets for this journey start at £19 but you can travel from only £7 by coach.
There are 16 trains per day. The earliest train runs at 05:53, the last at 18:53. The fastest train covers the 205 km distance in 2h 0m.
Distance 205 km |
Average train duration 3h 26m |
Cheapest ticket price £19 |
Trains per day 24 |
Direct trains 16 |
Fastest train 2h 0m |
First train 05:53 |
Last train 18:53 |
Train companies: Italo, Frecciarossa, Regionale, Intercity, Intercity Notte from Venice Mestre to Florence Santa Maria Novella trainsItalo, Frecciarossa, Regionale, Intercity, Intercity Notte trains will get you between Venice Mestre and Florence Santa Maria Novella from £7. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Frecciarossa
Regionale
Intercity
Intercity Notte
FAQs: Venice Mestre to Florence Santa Maria Novella train
Find answers to the most common questions about traveling from Venice Mestre to Florence Santa Maria Novella by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Venice Mestre and Florence Santa Maria Novella
- Mon - Sun: 05:50 - 20:30
- Provided by KiPoint and located on the ground floor.
- McDonald’s
- Chock Full O'Nuts
- Puro Gusto
- Juice Bar
- Rossosapore
- Full accessibility facilities, including toilets, ramps, wheelchairs, elevators and a mobility assistance center.
- Best Western Hotel Tritone
- The Plaza Hotel
- Hotel Villa Constanza
- Mon - Sun: 05:50 - 20:30
- Located in the main concourse.
- Bus lines: 2, 3, 10, 15, 18, 25a, 31, 31H, 32, 32H, 33H, 34H, 43, 53, 86, N1, 8AE
- Train lines: FR, FA, FB, EC, RJ, IC, EN, ICN, R, Italo
- Mon - Sun: 06:00 - 21:00
- Free WiFi (30 minutes limit).
- Provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
- 12oz Coffee Joint
- Casa Maioli
- Don Nino
- Fratelli Cuore
- McDonald´s
- Panella
- Segafredo Zanetti
- Spizzico
- Venchi
- & many more
- Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
- Hotel Luxor Florence
- Joy Hotel Florence
- Diplomat Hotel Florence
- Mon - Sun: 06:00 - 21:00
- Located inside and outside the station.
- Tram lines: T1, T2
- Bus lines: 6, 11, 12, 13, 17, 23, 36, 37, C4
- Train lines: FR, FA, Italo
Most popular train connections from Venice Mestre
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