The cheapest and fastest trains from Santa Margherita Ligure-Portofino to Milan Centrale
Cheapest price
£15
Average price
£20
Fastest journey
2 h 18 m
Average duration
2 h 22 m
Trains per day
23
Distance
128 km
The best way to find a cheap train ticket from Santa Margherita Ligure-Portofino to Milan Centrale is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Santa Margherita Ligure-Portofino to Milan Centrale will cost around £20 if you buy it on the day, but you can find cheap train tickets today for only £15.
Of the 23 trains that leave Santa Margherita Ligure-Portofino for Milan Centrale every day 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct trains cover the 128 km distance in an average of 2 h 22 m but if you time it right, some trains will get you there in just 2 h 18 m .
The slowest trains will take 2 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Regionale 12372 · Regionale Veloce 307111:573h38Santa Margherita Ligure-Portofino15:35Milan Centrale£151One-way1 change
Regionale 12316 · Regionale Veloce 30196:323h03Santa Margherita Ligure-Portofino9:35Milan Centrale£151One-way1 change
Regionale Veloce 3261 · Regionale Veloce 302810:582h37Santa Margherita Ligure-Portofino13:35Milan Centrale£151One-way1 change
Regionale 12458 · Regionale Veloce 2146 · Regionale Veloce 304720:143h21Santa Margherita Ligure-Portofino23:35Milan Centrale£151One-way2 changes
Regionale 12396 · Regionale Veloce 307514:143h21Santa Margherita Ligure-Portofino17:35Milan Centrale£151One-way1 change
Intercity 6526:072h18Santa Margherita Ligure-Portofino8:25Milan Centrale£211One-way0 changes
Intercity 68017:462h19Santa Margherita Ligure-Portofino20:05Milan Centrale£281One-way0 changes
Intercity 67415:462h19Santa Margherita Ligure-Portofino18:05Milan Centrale£211One-way0 changes
Intercity 6587:392h21Santa Margherita Ligure-Portofino10:00Milan Centrale£211One-way0 changes
Regionale 12216+
Intercity 6628:202h35Santa Margherita Ligure-Portofino10:55Milan Centrale£241One-way1 change
Travel Information
Compare train and coach for Santa Margherita Ligure-Portofino to Milan Centrale
Omio recommends booking the train as it is the most popular option from Santa Margherita Ligure-Portofino to Milan Centrale among Omio's users. If you are prioritising price take the coach with prices starting from £5. For those with little time consider booking a coach which can get you there in 1h 48m. The ticket price range depends on the travel mode: a coach costs an average of £5, and a train costs an average of £14.
Distance: 128 km
Compare train with
Most popular Train | Coach |
|---|---|
£15 Average Price | £7 Average Price Cheapest |
3h 1m Average total duration 2h 31m Onboard + 30m Additional time* | 2h 18m Average total duration Fastest 1h 48m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Santa Margherita Ligure-Portofino to Milan Centrale train times
The table below shows live departures for Santa Margherita Ligure-Portofino to Milan Centrale trains for today, Saturday 6 June. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
Regionale Veloce 3274 · Regionale 12076 · Regionale Veloce 3079 | 16:46 Santa Margherita Ligure-Portofino | 2h49 | 19:35 Milan Centrale | 2 changes | |
Intercity 680 | 17:46 Santa Margherita Ligure-Portofino | 2h19 | 20:05 Milan Centrale | 0 changesdirect | |
Regionale Veloce 3096+ FRECCIABIANCA 8620 | 18:03 Santa Margherita Ligure-Portofino | 2h37 | 20:40 Milan Centrale | 1 change | |
Regionale 12438+ Intercity 681 | 18:10 Santa Margherita Ligure-Portofino | 2h55 | 21:05 Milan Centrale | 1 change | |
Regionale Veloce 3278 · Regionale Veloce 3044 | 18:46 Santa Margherita Ligure-Portofino | 2h49 | 21:35 Milan Centrale | 1 change | |
Intercity 684 | 19:46 Santa Margherita Ligure-Portofino | 2h14 | 22:00 Milan Centrale | 0 changesdirect | |
Regionale 12452+ Intercity 639 | 19:55 Santa Margherita Ligure-Portofino | 3h00 | 22:55 Milan Centrale | 1 change | |
Regionale 12452 · Regionale Veloce 3047 | 19:55 Santa Margherita Ligure-Portofino | 3h40 | 23:35 Milan Centrale | 1 change | |
Regionale 12458 · Regionale Veloce 2146 · Regionale Veloce 3047 | 20:14 Santa Margherita Ligure-Portofino | 3h21 | 23:35 Milan Centrale | 2 changes | |
Intercity 679 · Intercity 518+ Regionale Veloce 3047 | 20:16 Santa Margherita Ligure-Portofino | 3h19 | 23:35 Milan Centrale | 2 changes | |
Regionale Veloce 3016 | 4:55 Santa Margherita Ligure-Portofino | 2h40 | 7:35 Milan Centrale | 0 changesdirect | |
Intercity 652 | 6:07 Santa Margherita Ligure-Portofino | 2h18 | 8:25 Milan Centrale | 0 changesdirect | |
Regionale 12316 · Regionale Veloce 3019 | 6:32 Santa Margherita Ligure-Portofino | 3h03 | 9:35 Milan Centrale | 1 change | |
Regionale 12322 · Regionale Veloce 2120 · Regionale Veloce 2023 | 7:20 Santa Margherita Ligure-Portofino | 5h25 | 12:45 Milan Centrale | 2 changes | |
Intercity 658 | 7:39 Santa Margherita Ligure-Portofino | 2h21 | 10:00 Milan Centrale | 0 changesdirect | |
Regionale 12216+ Intercity 662 | 8:20 Santa Margherita Ligure-Portofino | 2h35 | 10:55 Milan Centrale | 1 change | |
Regionale 12352+ Intercity 631 | 9:53 Santa Margherita Ligure-Portofino | 3h07 | 13:00 Milan Centrale | 1 change | |
Regionale Veloce 3261 · Regionale Veloce 3028 | 10:58 Santa Margherita Ligure-Portofino | 2h37 | 13:35 Milan Centrale | 1 change | |
Regionale 12372 · Regionale Veloce 3071 | 11:57 Santa Margherita Ligure-Portofino | 3h38 | 15:35 Milan Centrale | 1 change | |
Regionale 12372+ Intercity 745 | 11:57 Santa Margherita Ligure-Portofino | 3h03 | 15:00 Milan Centrale | 1 change | |
Regionale Veloce 3266 · Regionale 12044 · Regionale Veloce 3071 | 12:46 Santa Margherita Ligure-Portofino | 2h49 | 15:35 Milan Centrale | 2 changes | |
Regionale 12392+ Intercity 1539 | 13:56 Santa Margherita Ligure-Portofino | 3h04 | 17:00 Milan Centrale | 1 change | |
Regionale 12396 · Regionale Veloce 3075 | 14:14 Santa Margherita Ligure-Portofino | 3h21 | 17:35 Milan Centrale | 1 change | |
Regionale Veloce 3270 · Regionale 12052 · Regionale Veloce 3075 | 14:46 Santa Margherita Ligure-Portofino | 2h49 | 17:35 Milan Centrale | 2 changes | |
Intercity 674 | 15:46 Santa Margherita Ligure-Portofino | 2h19 | 18:05 Milan Centrale | 0 changesdirect | |
Regionale 12412+ Intercity 635 | 15:56 Santa Margherita Ligure-Portofino | 3h04 | 19:00 Milan Centrale | 1 change | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santa Margherita Ligure-Portofino to Milan Centrale by train or coach
Compare train and coach prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
06 Jun
07 Jun
08 Jun
09 Jun
10 Jun
11 Jun
12 Jun
13 Jun
14 Jun
15 Jun
16 Jun
17 Jun
18 Jun
19 Jun
20 Jun
21 Jun
22 Jun
23 Jun
24 Jun
25 Jun
26 Jun
Journey information
Overview: Train from Santa Margherita Ligure-Portofino to Milan Centrale
Trains from Santa Margherita Ligure-Portofino to Milan Centrale run on average 23 times per day, taking around 2h 31m. Cheap train tickets for this journey start at £14 but you can travel from only £5 by coach.
There are 5 trains per day. The earliest train runs at 02:55, the last at 19:14. The fastest train covers the 128 km distance in 2h 18m.
Distance 128 km |
Average train duration 2h 31m |
Cheapest ticket price £14 |
Trains per day 23 |
Direct trains 5 |
Fastest train 2h 18m |
First train 2:55 |
Last train 19:14 |
Cheapest Month Jun |
Cheapest Day Tue |
High Season Jul - Sept |
Low Season Oct - Dec |
Busiest Day Mon |
Least Busy Day Wed |
Train companies: Intercity, Regionale, Frecciabianca from Santa Margherita Ligure-Portofino to Milan Centrale trainsIntercity, Regionale, Frecciabianca trains will get you between Santa Margherita Ligure-Portofino and Milan Centrale from £5. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Intercity
Regionale
Frecciabianca
FAQs: Santa Margherita Ligure-Portofino to Milan Centrale train
Find answers to the most common questions about traveling from Santa Margherita Ligure-Portofino to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Santa Margherita Ligure-Portofino and Milan Centrale
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- Parking is available near the station, open 24/7.
- Ristorante Da Michele
- Trattoria Baicin
- Outside the main entrance.
- Elevators, ramps, restrooms.
- €1
- Hotel Laurin
- Hotel Metropole
- Hotel Jolanda
- Located in the main hall
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-3 for trains to Genoa and regional destinations
- Bus: Several lines available
- Ferry: Line 1 to Portofino
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Santa Margherita Ligure-Portofino
More options for your journey from Santa Margherita Ligure-Portofino to Milan Centrale
Here are some other resources that might have the information you need


