The cheapest and fastest trains from Florence Santa Maria Novella to Milan Centrale
Cheapest price
£27
Average price
£60
Fastest journey
1 h 55 m
Average duration
1 h 55 m
Trains per day
66
Distance
250 km
The best way to find a cheap train ticket from Florence Santa Maria Novella to Milan Centrale is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Florence Santa Maria Novella to Milan Centrale will cost around £60 if you buy it on the day, but you can find cheap train tickets today for only £27.
Of the 66 trains that leave Florence Santa Maria Novella for Milan Centrale every day 30 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct trains cover the 250 km distance in an average of 1 h 55 m but if you time it right, some trains will get you there in just 1 h 55 m .
The slowest trains will take 1 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Regionale 17800 · Autobus FI76V · Regionale Veloce TTPER 2460
Tuscany Line 18472 · Autobus TTPER B0442 · Regionale Veloce TTPER 2482
Tuscany Line 18478 · Autobus TTPER B0444 · Regionale Veloce TTPER 2486
Tuscany Line 18476 · Autobus FI58V · Regionale Veloce TTPER 2484
Regionale 18460 · Autobus TTPER B0430 · Regionale Veloce TTPER 2466
9962
9916
9948
9904
8158Travel Information
Compare coach, train and flight for Florence Santa Maria Novella to Milan Centrale
Omio recommends booking the train as it is the most popular option from Florence Santa Maria Novella to Milan Centrale among Omio's users. If you are prioritising price take the coach with prices starting from £8. For those with little time consider booking a train which can get you there in 3h 40m. The ticket price range depends on the travel mode: a coach costs an average of £8, and a flight costs an average of £94.
Distance: 250 km
Compare train with
Most popular Train | Coach | Flight |
|---|---|---|
£40 Average Price | £18 Average Price Cheapest | £170 Average Price |
4h 10m Average total duration Fastest 3h 40m Onboard + 30m Additional time* | 5h 3m Average total duration 4h 33m Onboard + 30m Additional time* | 12h 32m Average total duration 9h 32m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Florence Santa Maria Novella to Milan Centrale by coach, train or flight
Compare coach, train and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Florence Santa Maria Novella to Milan Centrale
Trains from Florence Santa Maria Novella to Milan Centrale run on average 37 times per day, taking around 3h 40m. Cheap train tickets for this journey start at £23 but you can travel from only £8 by coach.
There are 21 trains per day. The earliest train runs at 04:38, the last at 20:25. The fastest train covers the 250 km distance in 1h 55m.
Distance 250 km |
Average train duration 3h 40m |
Cheapest ticket price £23 |
Trains per day 37 |
Direct trains 21 |
Fastest train 1h 55m |
First train 04:38 |
Last train 20:25 |
Train companies: Italo, Frecciarossa, Intercity, Regionale, Intercity Notte from Florence Santa Maria Novella to Milan Centrale trainsItalo, Frecciarossa, Intercity, Regionale, Intercity Notte trains will get you between Florence Santa Maria Novella and Milan Centrale from £8. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Frecciarossa
Intercity
Regionale
Intercity Notte
FAQs: Florence Santa Maria Novella to Milan Centrale train
Find answers to the most common questions about traveling from Florence Santa Maria Novella to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Florence Santa Maria Novella and Milan Centrale
- Mon - Sun: 06:00 - 21:00
- Free WiFi (30 minutes limit).
- Provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
- 12oz Coffee Joint
- Casa Maioli
- Don Nino
- Fratelli Cuore
- McDonald´s
- Panella
- Segafredo Zanetti
- Spizzico
- Venchi
- & many more
- Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
- Hotel Luxor Florence
- Joy Hotel Florence
- Diplomat Hotel Florence
- Mon - Sun: 06:00 - 21:00
- Located inside and outside the station.
- Tram lines: T1, T2
- Bus lines: 6, 11, 12, 13, 17, 23, 36, 37, C4
- Train lines: FR, FA, Italo
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Florence Santa Maria Novella
More options for your journey from Florence Santa Maria Novella to Milan Centrale
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