The cheapest and fastest trains from Florence Santa Maria Novella to Milan Centrale
Cheapest price
£24
Average price
£52
Fastest journey
1 h 48 m
Average duration
1 h 54 m
Trains per day
35
Distance
250 km
The best way to find a cheap train ticket from Florence Santa Maria Novella to Milan Centrale is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Florence Santa Maria Novella to Milan Centrale will cost around £52 if you buy it on the day, but you can find cheap train tickets today for only £24.
Of the 35 trains that leave Florence Santa Maria Novella for Milan Centrale every day 11 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct trains cover the 250 km distance in an average of 1 h 54 m but if you time it right, some trains will get you there in just 1 h 48 m .
The slowest trains will take 1 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Regionale 18512 · Regionale 17824 · Regionale Veloce TTPER 247812:096h36Florence Santa Maria Novella18:45Milan Centrale£241One-way2 changes
Regionale 18482 · Regionale TTPER 17936 · Regionale Veloce TTPER 249418:374h53Florence Santa Maria Novella23:30Milan Centrale£241One-way2 changes
Regionale 18526 · Regionale 17838 · Regionale Veloce TTPER 248617:095h36Florence Santa Maria Novella22:45Milan Centrale£241One-way2 changes
Regionale 18520 · Regionale TTPER 17934 · Regionale Veloce TTPER 248215:095h36Florence Santa Maria Novella20:45Milan Centrale£241One-way2 changes
Regionale 17800 · Regionale Veloce TTPER 24604:325h13Florence Santa Maria Novella9:45Milan Centrale£241One-way1 change
FRECCIAROSSA 1000 963013:101h48Florence Santa Maria Novella14:58Milan Centrale£701One-way0 changes
99047:251h55Florence Santa Maria Novella9:20Milan Centrale£541One-way0 changes
99088:251h55Florence Santa Maria Novella10:20Milan Centrale£571One-way0 changes
FRECCIAROSSA 1000 95046:551h55Florence Santa Maria Novella8:50Milan Centrale£581One-way0 changes
FRECCIAROSSA 1000 95087:551h55Florence Santa Maria Novella9:50Milan Centrale£581One-way0 changes
Travel Information
Compare train, coach and flight for Florence Santa Maria Novella to Milan Centrale
Omio recommends booking the train as it is the most popular option from Florence Santa Maria Novella to Milan Centrale among Omio's users. If you are prioritising price take the coach with prices starting from £6. For those with little time consider booking a train which can get you there in 3h 38m. The ticket price range depends on the travel mode: a coach costs an average of £6, and a flight costs an average of £94.
Distance: 250 km
Compare train with
Most popular Train | Coach | Flight |
|---|---|---|
£36 Average Price | £13 Average Price Cheapest | £104 Average Price |
4h 8m Average total duration Fastest 3h 38m Onboard + 30m Additional time* | 4h 37m Average total duration 4h 7m Onboard + 30m Additional time* | 10h 19m Average total duration 7h 19m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Florence Santa Maria Novella to Milan Centrale train times
The table below shows live departures for Florence Santa Maria Novella to Milan Centrale trains for today, Saturday 11 April. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
FRECCIAROSSA 1000 9560 | 18:55 Florence Santa Maria Novella | 1h55 | 20:50 Milan Centrale | 0 changesdirect | |
FRECCIAROSSA 1000 9434 · FRECCIAROSSA 8830 | 19:20 Florence Santa Maria Novella | 2h05 | 21:25 Milan Centrale | 1 change | |
FRECCIAROSSA 9592 | 19:55 Florence Santa Maria Novella | 1h55 | 21:50 Milan Centrale | 0 changesdirect | |
Regionale 18251+ InterCityNotte 796+ Intercity 652 | 22:40 Florence Santa Maria Novella | 7h45 | 6:25 Milan Centrale | 2 changes | |
| Sunday 12 April | |||||
Regionale 17800 · Regionale Veloce TTPER 2460 | 2:32 Florence Santa Maria Novella | 5h13 | 7:45 Milan Centrale | 1 change | |
FRECCIAROSSA 1000 9504 | 4:55 Florence Santa Maria Novella | 1h55 | 6:50 Milan Centrale | 0 changesdirect | |
FRECCIAROSSA 1000 9400 · FRECCIAROSSA 9802 | 5:20 Florence Santa Maria Novella | 2h15 | 7:35 Milan Centrale | 1 change | |
9904 | 5:25 Florence Santa Maria Novella | 1h55 | 7:20 Milan Centrale | 0 changesdirect | |
Regionale 94453 · Regionale Veloce TTPER 3910 · Regionale Veloce TTPER 2470 | 5:29 Florence Santa Maria Novella | 7h16 | 12:45 Milan Centrale | 2 changes | |
FRECCIAROSSA 1000 9508 | 5:55 Florence Santa Maria Novella | 1h55 | 7:50 Milan Centrale | 0 changesdirect | |
9908 | 6:25 Florence Santa Maria Novella | 1h55 | 8:20 Milan Centrale | 0 changesdirect | |
FRECCIAROSSA 1000 8502 · FRECCIAROSSA 9721 | 6:36 Florence Santa Maria Novella | 3h09 | 9:45 Milan Centrale | 1 change | |
Regionale 94467 · Regionale Veloce TTPER 3912 · Regionale TTPER 2472 | 6:40 Florence Santa Maria Novella | 7h05 | 13:45 Milan Centrale | 2 changes | |
Regionale Veloce 4019+ Intercity 670 | 7:28 Florence Santa Maria Novella | 6h27 | 13:55 Milan Centrale | 1 change | |
FRECCIAROSSA 9516 | 7:55 Florence Santa Maria Novella | 1h55 | 9:50 Milan Centrale | 0 changesdirect | |
Regionale 18510 · Regionale 17820+ Intercity 606 | 8:09 Florence Santa Maria Novella | 5h21 | 13:30 Milan Centrale | 2 changes | |
Regionale 18510 · Regionale 17820 · Regionale Veloce TTPER 2490 | 8:09 Florence Santa Maria Novella | 6h36 | 14:45 Milan Centrale | 2 changes | |
FRECCIAROSSA 9490 · FRECCIAROSSA 8810 | 8:20 Florence Santa Maria Novella | 2h10 | 10:30 Milan Centrale | 1 change | |
FRECCIAROSSA 1000 9414 · FRECCIAROSSA 9806 | 9:20 Florence Santa Maria Novella | 2h05 | 11:25 Milan Centrale | 1 change | |
Regionale 18287+ Intercity 510+ Regionale Veloce 3075 | 9:28 Florence Santa Maria Novella | 6h07 | 15:35 Milan Centrale | 2 changes | |
FRECCIAROSSA 9524 | 9:55 Florence Santa Maria Novella | 1h55 | 11:50 Milan Centrale | 0 changesdirect | |
Regionale 18512 · Regionale 17824 · Regionale Veloce TTPER 2478 | 10:09 Florence Santa Maria Novella | 6h36 | 16:45 Milan Centrale | 2 changes | |
FRECCIAROSSA 1000 9416 · FRECCIAROSSA 8814 | 10:20 Florence Santa Maria Novella | 2h05 | 12:25 Milan Centrale | 1 change | |
FRECCIAROSSA 1000 9630 | 11:10 Florence Santa Maria Novella | 1h48 | 12:58 Milan Centrale | 0 changesdirect | |
Regionale 94457+ Intercity 610+ Regionale TRENORD 2642 | 11:40 Florence Santa Maria Novella | 6h55 | 18:35 Milan Centrale | 2 changes | |
FRECCIAROSSA 9584 | 12:55 Florence Santa Maria Novella | 1h55 | 14:50 Milan Centrale | 0 changesdirect | |
Regionale 18520 · Regionale TTPER 17934 · Regionale Veloce TTPER 2482 | 13:09 Florence Santa Maria Novella | 5h36 | 18:45 Milan Centrale | 2 changes | |
Regionale 18522+ Intercity 590 | 14:09 Florence Santa Maria Novella | 4h41 | 18:50 Milan Centrale | 1 change | |
Regionale 18526 · Regionale 17838 · Regionale Veloce TTPER 2486 | 15:09 Florence Santa Maria Novella | 5h36 | 20:45 Milan Centrale | 2 changes | |
Regionale 18307 · Regionale 2296 | 15:28 Florence Santa Maria Novella | 5h54 | 21:22 Milan Centrale | 1 change | |
Regionale 94459 · Regionale Veloce TTPER 2494 | 15:40 Florence Santa Maria Novella | 5h50 | 21:30 Milan Centrale | 1 change | |
Regionale 18482 · Regionale TTPER 17936 · Regionale Veloce TTPER 2494 | 16:37 Florence Santa Maria Novella | 4h53 | 21:30 Milan Centrale | 2 changes | |
Regionale 18532+ Intercity 1588 | 18:09 Florence Santa Maria Novella | 4h06 | 22:15 Milan Centrale | 1 change | |
This is the last train of the day. | |||||
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Compare prices and tickets Florence Santa Maria Novella to Milan Centrale by train, coach or flight
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Why should you book Florence Santa Maria Novella to Milan Centrale trains with Omio?
Why book with Omio vs Italo?
- Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Frecciarossa, Intercity, Regionale or Intercity Notte to find the best option for your trip from Florence Santa Maria Novella to Milan Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Italo with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Florence Santa Maria Novella to Milan Centrale.
Journey information
Overview: Train from Florence Santa Maria Novella to Milan Centrale
Trains from Florence Santa Maria Novella to Milan Centrale run on average 40 times per day, taking around 3h 38m. Cheap train tickets for this journey start at £16 but you can travel from only £6 by coach.
There are 22 trains per day. The earliest train runs at 03:32, the last at 22:13. The fastest train covers the 250 km distance in 1h 55m.
Distance 250 km |
Average train duration 3h 38m |
Cheapest ticket price £16 |
Trains per day 40 |
Direct trains 22 |
Fastest train 1h 55m |
First train 3:32 |
Last train 22:13 |
Train companies: Italo, Frecciarossa, Intercity, Regionale, Intercity Notte from Florence Santa Maria Novella to Milan Centrale trainsItalo, Frecciarossa, Intercity, Regionale, Intercity Notte trains will get you between Florence Santa Maria Novella and Milan Centrale from £6. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Frecciarossa
Intercity
Regionale
Intercity Notte
FAQs: Florence Santa Maria Novella to Milan Centrale train
Find answers to the most common questions about traveling from Florence Santa Maria Novella to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Florence Santa Maria Novella and Milan Centrale
- Mon - Sun: 06:00 - 21:00
- Free WiFi (30 minutes limit).
- Provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
- 12oz Coffee Joint
- Casa Maioli
- Don Nino
- Fratelli Cuore
- McDonald´s
- Panella
- Segafredo Zanetti
- Spizzico
- Venchi
- & many more
- Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
- Hotel Luxor Florence
- Joy Hotel Florence
- Diplomat Hotel Florence
- Mon - Sun: 06:00 - 21:00
- Located inside and outside the station.
- Tram lines: T1, T2
- Bus lines: 6, 11, 12, 13, 17, 23, 36, 37, C4
- Train lines: FR, FA, Italo
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Florence Santa Maria Novella
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