The cheapest and fastest trains from Milan to Karlsruhe
Cheapest price
£46
Average price
£46
Fastest journey
6 h 19 m
Average duration
6 h 19 m
Trains per day
1
Distance
398 km
The best way to find a cheap train ticket from Milan to Karlsruhe is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Milan to Karlsruhe will cost around £46 if you buy it on the day, but you can find cheap train tickets today for only £46.
Of the 1 trains that leave Milan for Karlsruhe every day 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct trains cover the 398 km distance in an average of 6 h 19 m but if you time it right, some trains will get you there in just 6 h 19 m .
The slowest trains will take 6 h 19 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare train, coach and flight for Milan to Karlsruhe
Omio recommends booking the train as it is the most popular option from Milan to Karlsruhe among Omio's users. If you are prioritising price take the coach with prices starting from £22. For those with little time consider booking a flight which can get you there in 1h 7m. The ticket price range depends on the travel mode: a coach costs an average of £22, and a train costs an average of £74.
Distance: 398 km
Compare train with
Most popular Train | Coach | Flight |
|---|---|---|
£110 Average Price | £39 Average Price Cheapest | £65 Average Price |
6h 38m Average total duration 6h 8m Onboard + 30m Additional time* | 10h 55m Average total duration 10h 25m Onboard + 30m Additional time* | 4h 7m Average total duration Fastest 1h 7m Onboard + 3h 0m Additional time* |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Live departures
Milan to Karlsruhe train times
The table below shows live departures for Milan to Karlsruhe trains for today, Monday 1 December. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
![]() | 09:10 Milan | 6h19 | 15:29 Karlsruhe | 0 changesdirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan to Karlsruhe by train, coach or flight
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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How far in advance should I book train tickets from Milan to Karlsruhe?
Journey information
Overview: Train from Milan to Karlsruhe
Trains from Milan to Karlsruhe run on average 1 times per day, taking around 6h 8m. Cheap train tickets for this journey start at £74 but you can travel from only £21 by flight.
The earliest train runs at 00:06, the last at 21:50. The fastest train covers the 398 km distance in 6h 19m.
Distance 398 km |
Average train duration 6h 8m |
Cheapest ticket price £74 |
Trains per day 1 |
Fastest train 6h 19m |
First train 00:06 |
Last train 21:50 |
Train companies: Deutsche Bahn, Trenitalia, Trenitalia EuroCity from Milan to Karlsruhe trainsDeutsche Bahn, Trenitalia, Trenitalia EuroCity trains will get you between Milan and Karlsruhe from £21. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Trenitalia
Trenitalia EuroCity
FAQs: Milan to Karlsruhe train
Find answers to the most common questions about traveling from Milan to Karlsruhe by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Karlsruhe, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Milan and Karlsruhe
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
- Monday: 06:30 - 21:00
- Tuesday: 06:30 - 21:00
- Wednesday: 06:30 - 21:00
- Thursday: 06:30 - 21:00
- Friday: 06:30 - 21:00
- Saturday: 08:00 - 19:00
- Sunday: 09:00 - 20:00
- Vinarte
- Am Tiergarten
- Panorama
- Alter Brauhof
- Hotel Barbarossa
- Hotel Avisa
- Am Tiergarten
- Aparthotel Aijana
- Monday: 08:00 13:30 - 12:30 18:00
- Tuesday: 08:00 13:30 - 12:30 18:00
- Wednesday: 08:00 13:30 - 12:30 18:00
- Thursday: 08:00 13:30 - 12:30 18:00
- Friday: 08:00 13:30 - 12:30 18:00
- Saturday: 09:00 - 13:00
- Hubraum
- Vogel Hausbräu Durlach
- Asia Gourmet
- Borsalino
- Hotel Große Linde
- Zum Erwin
- Der Blaue Reiter
- Adler
- Denkfabrik
- Cafeteria
- Asia Imbiss
- Auerhahn
More options for your journey from Milan to Karlsruhe
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