- Must visit
Magritte Museum
Compact museum dedicated to René Magritte, presenting paintings, archives and context for Belgium’s celebrated Surrealist artist.
Flights from Santander to Brussels depart on average 8 times per day, taking around 3h 6m. Cheap flight tickets for this journey start at £17 if you book in advance.
There are 1 flights per day. The earliest flight runs at 05:53, the last at 22:15. The fastest flight covers the 1026 km distance in 1h 50m. February is the cheapest month to fly.
Distance 1026 km |
Average flight duration 3h 6m |
Cheapest ticket price £17 |
Flights per day 8 |
Direct flights 1 |
Fastest flight 1h 50m |
First flight 5:53 |
Last flight 22:15 |
Cheapest Month Feb |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Mon |
Least Busy Day Sun |
Best time to book 42 days |
Cheapest price
£147
Average price
£329
Fastest journey
4 h 50 m
Average duration
5 h 42 m
Flights per day
12
Distance
1026 km
The best way to find a cheap flight ticket from Santander to Brussels is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Santander to Brussels will cost around £329 if you buy it on the day, but you can find cheap flight tickets today for only £147.
To travel from Santander to Brussels you need to make at least one change.
VY1597 · VY8988
IB1064 · IB603
IB1060 · IB603
IB1066 · IB597
IB1066 · IB601
IB1064 · IB603
VY1597 · VY8988
IB1066 · IB597
IB5353 · IB5690
IB1060 · IB601Omio recommends booking the flight as it is the most popular option from Santander to Brussels among Omio's users. If you are prioritising price take the coach with prices starting from £56. For those with little time consider booking a flight which can get you there in 3h 6m. The ticket price range depends on the travel mode: a coach costs an average of £56, and a flight costs an average of £17.
Distance: 1026 km
Most popular Flight | Coach |
|---|---|
£114 Average Price | £100 Average Price Cheapest |
6h 6m Average total duration Fastest 3h 6m Onboard + 3h 0m Additional time* | 18h 37m Average total duration 18h 7m Onboard + 30m Additional time* |
![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options |
The table below shows live departures for Santander to Brussels flights for today, Sunday 2 August. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
IB1064 · IB603 | 17:40 Santander Airport | 4h50 | 22:30 Brussels Airport | 1 change | |
| Monday 3 August | |||||
IB1066 · IB731+ 9370 | 6:30 Santander Airport | 11h36 | 18:06 Brussels-Midi | 2 changes | |
IB1066 · IB737+ 9370 | 6:30 Santander Airport | 11h36 | 18:06 Brussels-Midi | 2 changes | |
IB1066 · IB601 | 6:30 Santander Airport | 12h30 | 19:00 Brussels Airport | 1 change | |
IB1066 · IB597 | 6:30 Santander Airport | 4h55 | 11:25 Brussels Airport | 1 change | |
IB1066 · IB737+ 9398 | 6:30 Santander Airport | 16h36 | 23:06 Brussels-Midi | 2 changes | |
IB1060 · IB603 | 10:05 Santander Airport | 12h25 | 22:30 Brussels Airport | 1 change | |
IB1060 · IB733+ 9398 | 10:05 Santander Airport | 13h01 | 23:06 Brussels-Midi | 2 changes | |
IB1060 · IB601 | 10:05 Santander Airport | 8h55 | 19:00 Brussels Airport | 1 change | |
IB1060+ BA7056+ BA438+ 9398 | 10:05 Santander Airport | 13h01 | 23:06 Brussels-Midi | 3 changes | |
Find all the dates and times for this journey
Compare coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Compact museum dedicated to René Magritte, presenting paintings, archives and context for Belgium’s celebrated Surrealist artist.
Major fine arts museum with Flemish, Belgian and European works, ideal for tracing artistic developments across centuries.
Art Nouveau house designed by Victor Horta, offering an intimate look at architecture, interiors and decorative detail.
Historic square packed with ornate façades, seasonal events and evening illumination; a natural starting point for exploring the centre.
A characterful shopping arcade with glass roof, elegant details and a classic route for a refined walk in the centre.
Landscaped hill with gardens, fountains and one of Brussels’ most rewarding skyline views near the upper town museums.
Moules-frites pairs North Sea mussels with crisp chips. It is a Brussels brasserie classic, especially popular in cooler months.
Stoemp is mashed potatoes mixed with seasonal vegetables, often served with sausage or bacon. It is a comforting Brussels staple.
Carbonnade flamande is a slow-cooked beef and onion stew made with Belgian beer. It is a beloved hearty dish in Brussels cafés.
Refined Belgian dining in the Galeries Royales Saint-Hubert, known for well-presented regional dishes and a polished atmosphere.
Traditional restaurant famed for mussels, oysters and other Belgian seafood dishes in a lively, classic brasserie setting.
Long-running brasserie serving stoemp, carbonnade and other Belgian staples in an elegant Art Nouveau-inspired dining room.
Moderate for Western Europe: hotels and restaurants are not cheap, but public transport is reasonable and budget eats are easy to find.
Service is usually included. Round up or leave 5-10% for excellent restaurant service. Taxis are often rounded up. Small change is appreciated in cafés, but not expected.
Official public transport app
Brussels South Charleroi Airport -> Bruxelles-Midi
Find answers to the most common questions about traveling from Santander to Brussels by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

Most Santander to Brussels flights use the Santander Airport to Brussels Airport airport pair, with some services landing at Brussels South Charleroi Airport. Use this guide to compare Santander and Brussels airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Santander Airport is 4 km from Santander city centre. Public transport options include:
Santander Airport has practical services for this route, including Wifi, Shopping, Parking, ATM, Taxis, Accessibility, WC, Lounge and Lost and Found Office.
Free Wi-Fi available throughout the airport. ATMs are located in the terminal.
Lost and found is available at the station.
Available at Santander Airport: Parking, Taxis, WC.
Accessibility facilities are available at Santander Airport: Elevators, ramps.
Brussels Airport is 1 km from Brussels city centre. Public transport options include:
Brussels Airport has practical services for this route, including Wifi, Shopping, Parking, ATM, Taxis, Accessibility, WC, Shower, Lounge and Lost and Found Office.
Free Wi-Fi available throughout the airport. ATMs are located in the departures and arrivals areas.
Lost and found is available at the station.
Available at Brussels Airport: Parking, Taxis, WC.
Accessibility facilities are available at Brussels Airport: Elevators, ramps, assistance.
Brussels South Charleroi Airport is 5 km from Brussels city centre. Public transport options include:
Brussels South Charleroi Airport has practical services for this route, including Wifi, Shopping, Parking, ATM, Taxis, Accessibility, WC, Shower, Lounge and Lost and Found Office.
Free Wi-Fi available throughout the airport. ATMs are located in the terminal.
Lost and found is available at the station.
Available at Brussels South Charleroi Airport: Parking, Taxis, WC.
Accessibility facilities are available at Brussels South Charleroi Airport: Ramps, assistance.
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