Travel Information
Compare coach and flight for Santander to Brussels
Omio recommends booking the flight as it is the most popular option from Santander to Brussels among Omio's users. If you are prioritising price take the coach with prices starting from £57. For those with little time consider booking a flight which can get you there in 3h 6m. The ticket price range depends on the travel mode: a coach costs an average of £57, and a flight costs an average of £17.
Distance: 1026 km
Compare flight with
Most popular Flight | Coach |
|---|---|
£115 Average Price | £100 Average Price Cheapest |
6h 6m Average total duration Fastest 3h 6m Onboard + 3h 0m Additional time* | 18h 37m Average total duration 18h 7m Onboard + 30m Additional time* |
![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options |
Travel optionsfrom Santander to Brussels
How to get to Brussels from Santander by train, bus, flight or ferry.
Our recommendation
The best way to travel from Santander to Brussels is by taking a coach because it’s the best combination of price and speed.
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3164 · 146619:3018h00Santander, Estación de Autobuses13:30Brussels, Brussels South (Gare du Midi)£481One-way2 changes
Cheapest
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3164 · 146619:3018h00Santander, Estación de Autobuses13:30Brussels, Brussels South (Gare du Midi)£481One-way2 changes
Fastest
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3164 · 146619:3018h00Santander, Estación de Autobuses13:30Brussels, Brussels South (Gare du Midi)£481One-way2 changes
Other options
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3164 · 146618:4018h50Santander, Estación de Autobuses13:30Brussels, Brussels South (Gare du Midi)£481One-way2 changes
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3164 · 146617:0020h30Santander, Estación de Autobuses13:30Brussels, Brussels South (Gare du Midi)£481One-way2 changes
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3164 · 146616:3021h00Santander, Estación de Autobuses13:30Brussels, Brussels South (Gare du Midi)£481One-way2 changes
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, coaches, flights and ferries
Compare coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Santander to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Santander to Brussels.

This is compared to other travel options from Santander to Brussels:
A coach is £14 less than a flight for this route with tickets for a flight from Santander to Brussels costing on average £115.
Other travel options to Brussels take longer:
Coach takes on average 18h 7m.
- Around 8 flights per day.
- Around 2 coaches per day.
However, we recommend checking specific travel dates for your route between Santander and Brussels as scheduled services by coach and flight can vary by season or day of the week.
- Flights mostly depart from Santander Airport and arrive in Brussels Airport.
- Coaches mostly depart from Santander, Estación de Autobuses and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with Ryanair, Vueling, Iberia, Air Nostrum to go to Brussels by flight.
- Travel with FlixBus, BlaBlaCar Bus to go to Brussels by coach.
- 1 direct flights per day with Ryanair.
Travelling from Santander to Brussels: related information
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