- Must visit
Vatican Museums
World-renowned Vatican collections with Raphael Rooms and the Sistine Chapel, essential for art and Church history.
Cheapest price
£17
Average price
£33
Fastest journey
3 h 37 m
Average duration
3 h 55 m
Buses per day
6
Distance
213 km
The best way to find a cheap coach ticket from Sant'Agnello to Rome is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Sant'Agnello to Rome will cost around £33 if you buy it on the day, but you can find cheap coach tickets today for only £17.
Of the 6 buses that leave Sant'Agnello for Rome every day 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct buses cover the 213 km distance in an average of 3 h 55 m but if you time it right, some buses will get you there in just 3 h 37 m .
The slowest buses will take 4 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus · FlixBus
23 - 23R
22-22R
FlixBus
Itabus | 1002 · 9954
22-22R
Itabus | 1002 · 9954
23 - 23R
Itabus | 1002 · 9954
FlixBusOmio recommends booking the coach as it is the most popular option from Sant'Agnello to Rome among Omio's users. If you are prioritising price take the coach with prices starting from £5. For those with little time consider booking a flight which can get you there in 1h 12m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.2kg. The ticket price range depends on the travel mode: a coach costs an average of £5, and a flight costs an average of £56.
Distance: 213 km
Most popular Coach | Train | Flight |
|---|---|---|
£18 Average Price Cheapest | £44 Average Price | £104 Average Price |
3h 48m Average total duration 3h 18m Onboard + 30m Additional time* | 2h 18m Average total duration 1h 48m Onboard + 30m Additional time* | 4h 12m Average total duration Fastest 1h 12m Onboard + 3h 0m Additional time* |
0.2 - 0.5kg CO2 emissions | 0.1 - 0.2kg CO2 emissions Lowest | 0.6 - 1.3kg CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The table below shows live departures for Sant'Agnello to Rome coaches for tomorrow, Monday 3 August. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
22-22R | 6:08 Sant'Agnello, Corso Italia (Bar Siesta) | 3h37 | 9:45 Roma, Autostazione Tiburtina | 0 changesdirect | |
FlixBus | 6:20 Sant'Agnello, Corso Italia / Via Don Minzoni (Town Hall) | 4h20 | 10:40 Roma, Autostazione Tiburtina | 0 changesdirect | |
FlixBus · FlixBus | 6:20 Sant'Agnello, Corso Italia / Via Don Minzoni (Town Hall) | 5h30 | 11:50 Roma, Autostazione (Metro Anagnina) | 1 change | |
Itabus | 1002 · 9954 | On time 14:45 Sant'Agnello | 4h03 | 18:48 Rome Tiburtina | 1 change | |
Itabus | 1002 · 9954 | On time 14:45 Sant'Agnello | 3h45 | 18:30 Rome Termini | 1 change | |
23 - 23R | 16:10 Sant'Agnello, Corso Italia (Bar Siesta) | 3h50 | 20:00 Roma, Autostazione Tiburtina | 0 changesdirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Sant'Agnello to Rome run on average 7 times per day, taking around 3h 18m. Cheap bus tickets for this journey start at £5 if you book in advance.
There are 6 coaches per day. The earliest coach runs at 03:20, the last at 23:40. The fastest coach covers the 213 km distance in 2h 40m.
Distance 213 km |
Average bus duration 3h 18m |
Cheapest ticket price £5 |
Buses per day 7 |
Direct buses 6 |
Fastest bus 2h 40m |
First bus 3:20 |
Last bus 23:40 |
Cheapest Month Mar |
Cheapest Day Mon |
High Season Jul - Sept |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Fri |
Best time to book 35 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-renowned Vatican collections with Raphael Rooms and the Sistine Chapel, essential for art and Church history.
Superb Capitoline collections on Michelangelo's square, showcasing ancient sculpture, bronzes, and Rome's civic history.
Outstanding gallery in a villa setting, celebrated for Bernini sculptures and masterpieces by Caravaggio and Raphael.
Baroque square with fountains and lively street life, ideal for people-watching and a classic Rome atmosphere.
Famous staircase linking Piazza di Spagna to Trinità dei Monti, beloved for city scenes and elegant surroundings.
Bohemian quarter of lanes, piazzas, and nightlife, popular for evening strolls, local character, and riverside charm.
Roman pasta with guanciale, egg yolk, Pecorino Romano and black pepper. A city icon prized for its rich sauce and no cream tradition.
Pasta in a sharp, savoury sauce of guanciale, tomato and Pecorino Romano. A classic Roman favourite with roots in local trattoria cooking.
Simple Roman pasta made with Pecorino Romano and black pepper. It shows the city’s love of bold flavour from few ingredients.
Michelin-starred restaurant by the Colosseum serving refined Roman cuisine in an elegant setting. Best for a fine-dining splurge.
Historic Trastevere trattoria known for classic Roman pasta and warm old-school rooms. A dependable choice for traditional local dishes.
Long-running Testaccio restaurant specialising in Roman quinto quarto and pasta. Informal, authentic and popular with locals and visitors.
Moderate for a major Western European capital. Hotels in central areas are pricey, but dining and public transport are often cheaper than in Paris or London.
Service is often included or covered by a coperto. Rounding up or leaving 5-10% is appreciated in restaurants. In cafés, small change is enough; taxis are usually rounded up.
Official public transport app
Via Marsala, Rome -> Piazza Venezia, Rome
Find answers to the most common questions about traveling from Sant'Agnello to Rome by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Sant'Agnello to Rome buses use the Napoli, Autostazione Metropark to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Sant'Agnello and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Roma, Via Marsala / Viale Enrico De Nicola is 1 km from Rome city centre. Public transport options include:
Roma, Via Marsala / Viale Enrico De Nicola has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food options include: Cafeteria della Stazione (in the station), Trattoria Marsala (0.2 km), Pizzeria Enrico (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance of the station.
Ticket office support is available at Roma, Via Marsala / Viale Enrico De Nicola.
Available at Roma, Via Marsala / Viale Enrico De Nicola: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Via Marsala / Viale Enrico De Nicola: Elevators, ramps.
Here are some other resources that might have the information you need