- Must visit
Vatican Museums
World-renowned Vatican collections with Raphael Rooms and the Sistine Chapel, essential for art and Church history.
Cheapest price
£66
Average price
£74
Fastest journey
17 h 10 m
Average duration
17 h 51 m
Buses per day
13
Distance
852 km
The best way to find a cheap coach ticket from Karlsruhe to Rome is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Karlsruhe to Rome will cost around £74 if you buy it on the day, but you can find cheap coach tickets today for only £66.
Of the 13 buses that leave Karlsruhe for Rome every day 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct buses cover the 852 km distance in an average of 17 h 51 m but if you time it right, some buses will get you there in just 17 h 10 m .
The slowest buses will take 18 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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FlixBus · FlixBusOmio recommends booking the coach as it is the most popular option from Karlsruhe to Rome among Omio's users. If you are prioritising price take the coach with prices starting from £39. For those with little time consider booking a train which can get you there in 12h 28m. In case you are seeking to minimise your carbon footprint the coach is your best bet as it emits only 0.9 - 2.1kg. The ticket price range depends on the travel mode: a coach costs an average of £39, and a train costs an average of £268.
Distance: 852 km
Most popular Coach | Train |
|---|---|
£63 Average Price Cheapest | £291 Average Price |
18h 21m Average total duration 17h 51m Onboard + 30m Additional time* | 12h 58m Average total duration Fastest 12h 28m Onboard + 30m Additional time* |
0.9 - 2.1kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The table below shows live departures for Karlsruhe to Rome coaches for today, Monday 24 August. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 9:30 Karlsruhe Hbf | 20h35 | 6:05 Roma, Autostazione (Metro Anagnina) | 1 change | |
FlixBus · FlixBus | 9:30 Karlsruhe Hbf | 20h05 | 5:35 Roma, Autostazione Tiburtina | 1 change | |
FlixTrain+ FlixBus · FlixBus | 10:26 Karlsruhe Hbf | 22h04 | 8:30 Roma, Autostazione Tiburtina | 2 changes | |
FlixBus · FlixBus | 12:30 Karlsruhe Hbf | 18h35 | 7:05 Roma, Autostazione Tiburtina | 1 change | |
FlixBus · FlixBus | 14:00 Karlsruhe Hbf | 19h30 | 9:30 Roma, Autostazione Tiburtina | 1 change | |
FlixTrain+ FlixBus · FlixBus | 15:29 Karlsruhe Hbf | 25h01 | 16:30 Roma, Autostazione Tiburtina | 2 changes | |
FlixBus · FlixBus | 17:05 Karlsruhe Hbf | 19h10 | 12:15 Roma, Autostazione (Metro Anagnina) | 1 change | |
FlixBus · FlixBus | 17:05 Karlsruhe Hbf | 18h45 | 11:50 Roma, Autostazione Tiburtina | 1 change | |
FlixBus | 20:10 Karlsruhe Hbf | 17h40 | 13:50 Roma, Autostazione Tiburtina | 0 changesdirect | |
FlixBus · FlixBus | 20:10 Karlsruhe Hbf | 18h55 | 15:05 Roma, Autostazione (Metro Anagnina) | 1 change | |
FlixBus · FlixBus | 22:40 Karlsruhe Hbf | 19h10 | 17:50 Roma, Autostazione (Metro Anagnina) | 1 change | |
FlixBus · FlixBus | 23:00 Karlsruhe Hbf | 19h05 | 18:05 Roma, Autostazione (Metro Anagnina) | 1 change | |
FlixBus · FlixBus | 23:40 Karlsruhe Hbf | 19h05 | 18:45 Roma, Autostazione Tiburtina | 1 change | |
FlixBus · FlixBus | 23:55 Karlsruhe Hbf | 23h50 | 23:45 Roma, Autostazione Tiburtina | 1 change | |
| Tuesday 25 August | |||||
FlixBus · FlixBus | 3:20 Karlsruhe Hbf | 17h50 | 21:10 Roma, Autostazione Tiburtina | 1 change | |
FlixBus · FlixBus | 4:55 Karlsruhe Hbf | 18h05 | 23:00 Roma, Autostazione Tiburtina | 1 change | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and coach prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Karlsruhe to Rome run on average 13 times per day, taking around 17h 51m. Cheap bus tickets for this journey start at £39 if you book in advance.
There are 1 coaches per day. The earliest coach runs at 00:05, the last at 23:55. The fastest coach covers the 852 km distance in 16h 25m.
Distance 852 km |
Average bus duration 17h 51m |
Cheapest ticket price £39 |
Buses per day 13 |
Direct buses 1 |
Fastest bus 16h 25m |
First bus 0:05 |
Last bus 23:55 |
Cheapest Month Jul |
Cheapest Day Mon |
High Season Jul - Sept |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Fri |
Best time to book 42 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-renowned Vatican collections with Raphael Rooms and the Sistine Chapel, essential for art and Church history.
Superb Capitoline collections on Michelangelo's square, showcasing ancient sculpture, bronzes, and Rome's civic history.
Outstanding gallery in a villa setting, celebrated for Bernini sculptures and masterpieces by Caravaggio and Raphael.
Baroque square with fountains and lively street life, ideal for people-watching and a classic Rome atmosphere.
Famous staircase linking Piazza di Spagna to Trinità dei Monti, beloved for city scenes and elegant surroundings.
Bohemian quarter of lanes, piazzas, and nightlife, popular for evening strolls, local character, and riverside charm.
Roman pasta with guanciale, egg yolk, Pecorino Romano and black pepper. A city icon prized for its rich sauce and no cream tradition.
Pasta in a sharp, savoury sauce of guanciale, tomato and Pecorino Romano. A classic Roman favourite with roots in local trattoria cooking.
Simple Roman pasta made with Pecorino Romano and black pepper. It shows the city’s love of bold flavour from few ingredients.
Michelin-starred restaurant by the Colosseum serving refined Roman cuisine in an elegant setting. Best for a fine-dining splurge.
Historic Trastevere trattoria known for classic Roman pasta and warm old-school rooms. A dependable choice for traditional local dishes.
Long-running Testaccio restaurant specialising in Roman quinto quarto and pasta. Informal, authentic and popular with locals and visitors.
Moderate for a major Western European capital. Hotels in central areas are pricey, but dining and public transport are often cheaper than in Paris or London.
Service is often included or covered by a coperto. Rounding up or leaving 5-10% is appreciated in restaurants. In cafés, small change is enough; taxis are usually rounded up.
Official public transport app
Via Marsala, Rome -> Piazza Venezia, Rome
Find answers to the most common questions about traveling from Karlsruhe to Rome by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Karlsruhe to Rome buses use the Karlsruhe Hbf to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Karlsruhe and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Karlsruhe, Hinterm Hauptbahnhof (Südeingang) is 1 km from Karlsruhe city centre. Public transport options include:
Karlsruhe, Hinterm Hauptbahnhof (Südeingang) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Wi-Fi is available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang). ATMs are available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang).
Ticket office support is available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang).
Available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang): Parking, Taxis, WC.
Accessibility facilities are available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang): The station is accessible for passengers with reduced mobility.
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Food options include: Cafes and vending machines available.
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Ticket office support is available at Roma, Autostazione Tiburtina.
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Here are some other resources that might have the information you need