The cheapest and fastest trains from Slough station (SLO) to Manchester Piccadilly (MAN)
Cheapest price on 18 Sept
£43
Average ticket price on 18 Sept
£60
Fastest journey on 18 Sept
3 h 50 m
Average journey duration on 18 Sept
5 h 27 m
Trains on 18 Sept
3
Distance
245 km
The best way to find a cheap train ticket from Slough station (SLO) to Manchester Piccadilly (MAN) is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Slough station (SLO) to Manchester Piccadilly (MAN) will cost around £60 if you buy it on the day, but you can find cheap train tickets today for only £43.
On Fri 18 Sept, we found 3 trains from Slough station (SLO) to Manchester Piccadilly (MAN), including 3 direct services.
These direct trains cover the 245 km distance in an average of 5 h 27 m but if you time it right, some trains will get you there in just 3 h 50 m .
The slowest trains will take 8 h 41 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
6:393h50Slough station (SLO)10:29Manchester Piccadilly (MAN)£431One-way0 changes
5:393h50Slough station (SLO)9:29Manchester Piccadilly (MAN)£431One-way0 changes
22:088h41Slough station (SLO)6:49Manchester Piccadilly (MAN)£941One-way0 changes
6:393h50Slough station (SLO)10:29Manchester Piccadilly (MAN)£431One-way0 changes
5:393h50Slough station (SLO)9:29Manchester Piccadilly (MAN)£431One-way0 changes
22:088h41Slough station (SLO)6:49Manchester Piccadilly (MAN)£941One-way0 changes
Travel Information
Compare train, coach and flight for Slough station (SLO) to Manchester Piccadilly (MAN)
Omio recommends booking the flight as it is the most popular option from Slough station (SLO) to Manchester Piccadilly (MAN) among Omio's users. If you are prioritising price, take the coach, with an average ticket price of £26 For those with little time, consider booking a flight, which has an average total journey time of 3h 37m. Average ticket prices depend on the travel mode: a coach costs an average of £26, while a flight costs an average of £303.
Distance: 245 km
Compare train with
| Train | Most popular Flight | Coach | Driving |
|---|---|---|---|
£90 Average Price | £303 Average Price | £26 Average Price Cheapest | £49 Average Price (fuel + tolls) |
3h 40m Average total duration 3h 10m Onboard + 30m Additional time* | 3h 37m Average total duration Fastest 1h 37m Onboard + 2h 0m Additional time* | 7h 9m Average total duration 6h 39m Onboard + 30m Additional time* | 3h 35m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Slough station (SLO) to Manchester Piccadilly (MAN):
A coach is £64 less than a train for this route with tickets for a train from Slough station (SLO) to Manchester Piccadilly (MAN) costing on average £90.
A coach is £278 less than a flight for this route with tickets for a flight from Slough station (SLO) to Manchester Piccadilly (MAN) costing on average £303.
Other travel options to Manchester Piccadilly (MAN) take longer:
Train takes on average 3h 10m.
Coach takes on average 6h 39m.
You'll arrive about 25m sooner (3h 10m by train vs 3h 35m by car). Tickets start at around £90 compared to roughly £49 in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
Live departures
Slough station (SLO) to Manchester Piccadilly (MAN) train times
The table below shows live departures for Slough station (SLO) to Manchester Piccadilly (MAN) trains for today, Thursday 17 September. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
C37702+ W34185+ Tube from Tottenham Court Road (Elizabeth line) to London Euston | On time 8:15 Slough station (SLO) | 3h29 | 11:44 Manchester Piccadilly (MAN) | 2 changes | |
G00739 · G00854+ C37231 | Delayed 7:51 8:17Slough station (SLO) | 3h42 | 11:59 Manchester Piccadilly (MAN) | 2 changes | |
G00855+ C37236 | Delayed 8:15 8:33Slough station (SLO) | 3h56 | 12:29 Manchester Piccadilly (MAN) | 1 change | |
C37753+ W34059+ Tube from Tottenham Court Road (Elizabeth line) to London Euston | On time 8:45 Slough station (SLO) | 3h20 | 12:05 Manchester Piccadilly (MAN) | 2 changes | |
C37770+ W34102+ Tube from Tottenham Court Road (Elizabeth line) to London Euston | On time 8:53 Slough station (SLO) | 3h26 | 12:19 Manchester Piccadilly (MAN) | 2 changes | |
G00698 · G66730+ C37256 | Delayed 8:43 9:03Slough station (SLO) | 3h56 | 12:59 Manchester Piccadilly (MAN) | 2 changes | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Slough station (SLO) to Manchester Piccadilly (MAN) by train, coach or flight
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
18 Sept
19 Sept
20 Sept
21 Sept
22 Sept
23 Sept
24 Sept
Why should you book Slough station (SLO) to Manchester Piccadilly (MAN) trains with Omio?
Why book with Omio vs CrossCountry?
- Compare with other providers: On Omio, you can not only buy tickets for CrossCountry, but also compare tickets for the likes of Avanti West Coast to find the best option for your trip from Slough station (SLO) to Manchester Piccadilly (MAN).
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare CrossCountry with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Slough station (SLO) to Manchester Piccadilly (MAN).
Why book with Omio over Wanderu or Raileurope?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Avanti West Coast to find the best option for your trip from Slough station (SLO) to Manchester Piccadilly (MAN).
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Slough station (SLO) to Manchester Piccadilly (MAN).
Journey information
Overview: Train from Slough station (SLO) to Manchester Piccadilly (MAN)
Trains from Slough station (SLO) to Manchester Piccadilly (MAN) run on average 5 times per day, taking around 3h 10m. Cheap train tickets for this journey start at £38 but you can travel from only £17 by coach.
The earliest train runs at 05:39, the last at 11:24. The fastest train covers the 245 km distance in 2h 37m.
Distance 245 km |
Average train duration 3h 10m |
Cheapest ticket price £38 |
Trains per day 5 |
Fastest train 2h 37m |
First train 5:39 |
Last train 11:24 |
Cheapest Month Aug |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Tue |
Least Busy Day Thu |
Train companies: CrossCountry, Avanti West Coast from Slough station (SLO) to Manchester Piccadilly (MAN) trainsCrossCountry, Avanti West Coast trains will get you between Slough station (SLO) and Manchester Piccadilly (MAN) from £17. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
CrossCountry
Avanti West Coast
FAQs: Slough station (SLO) to Manchester Piccadilly (MAN) train
Find answers to the most common questions about traveling from Slough station (SLO) to Manchester Piccadilly (MAN) by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Manchester Piccadilly (MAN), this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Slough station (SLO) and Manchester Piccadilly (MAN)
Most Slough station (SLO) to Manchester Piccadilly (MAN) trains use the Slough to Manchester Piccadilly station pair. Use this guide to compare Slough station (SLO) and Manchester Piccadilly (MAN) train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Getting to Slough from Slough city centre
Slough train station facilities and services
Slough has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk and Luggage Carts.
Food and drink
Food options include: The Moon and Spoon, The Red Lion
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Slough. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Slough. Lost and found is available at the station.
Parking, taxis and toilets
Available at Slough: Parking, Taxis, WC.
Bike and car services
Available at Slough: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Slough: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Holiday Inn Slough - Windsor, Moxy Slough, Travelodge Slough.
Getting to Manchester Piccadilly from Manchester city centre
Manchester Piccadilly train station facilities and services
Manchester Piccadilly has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental and Information Desk.
Food and drink
Food options include: Burger King, Caffè Nero, Carluccio’s, Hotel Chocolat, Starbucks, The Pasty Shop, Costa Coffee, Pret a Manger, Upper Crust, McDonald's, & more
Wi-Fi and ATMs
Pay as you go Wi-Fi is available through BT Wi-Fi. ATMs are there are ATM machines on the main concourse, Platform 10 and on the mezzanine level.
Tickets and information
The ticket office is open Mon - Sat: 04:30 - 22:30, Sun: 07:00 - 22:30. Information desks are located near the Fairfield Street entrance on the mezzanine level.
Luggage and lost property
Luggage storage is operated by Excess Baggage Co. Llocated between Platforms 10 and 11 and open daily from 08:00 to 21:00.
Parking, taxis and toilets
Available at Manchester Piccadilly: Parking, Taxis, WC.
Bike and car services
Available at Manchester Piccadilly: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Manchester Piccadilly: There is step-free access throughout the station. Ramps for train access and wheelchairs are also available.
Shops, hotels and contact
Nearby hotels include DoubleTree by Hilton Hotel Manchester - Piccadilly, Premier Inn Manchester City, Staycity Aparthotels - Manchester Piccadilly.



