The cheapest and fastest trains from Slough station (SLO) to Manchester Piccadilly (MAN)
Cheapest price
£91
Average price
£98
Fastest journey
3 h 16 m
Average duration
3 h 21 m
Trains per day
6
Distance
245 km
The best way to find a cheap train ticket from Slough station (SLO) to Manchester Piccadilly (MAN) is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Slough station (SLO) to Manchester Piccadilly (MAN) will cost around £98 if you buy it on the day, but you can find cheap train tickets today for only £91.
To travel from Slough station (SLO) to Manchester Piccadilly (MAN) you need to make at least 2 changes.
P33126+
Tube from London Paddington to London Euston+
W02604
L24015+
Tube from Tottenham Court Road (Elizabeth line) to London Euston+
W02533
G24224+
Tube from Tottenham Court Road (Elizabeth line) to London Euston+
W02535
G24239+
Tube from Tottenham Court Road (Elizabeth line) to London Euston+
W02606
P33120+
Tube from London Paddington to London Euston+
W02609
P33126+
Tube from London Paddington to London Euston+
W02604
P33120+
Tube from London Paddington to London Euston+
W02609
L24015+
Tube from Tottenham Court Road (Elizabeth line) to London Euston+
W02533
G24224+
Tube from Tottenham Court Road (Elizabeth line) to London Euston+
W02535
G24239+
Tube from Tottenham Court Road (Elizabeth line) to London Euston+
W02606Travel Information
Compare train, coach and flight for Slough station (SLO) to Manchester Piccadilly (MAN)
Omio recommends booking the train as it is the most popular option from Slough station (SLO) to Manchester Piccadilly (MAN) among Omio's users. If you are prioritising price take the coach with prices starting from £18. For those with little time consider booking a flight which can get you there in 1h 5m. The ticket price range depends on the travel mode: a coach costs an average of £18, and a train costs an average of £35.
Distance: 245 km
Compare train with
Most popular Train | Coach | Flight |
|---|---|---|
£55 Average Price | £23 Average Price Cheapest | £53 Average Price |
3h 43m Average total duration 3h 13m Onboard + 30m Additional time* | 5h 58m Average total duration 5h 28m Onboard + 30m Additional time* | 4h 5m Average total duration Fastest 1h 5m Onboard + 3h 0m Additional time* |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Live departures
Slough station (SLO) to Manchester Piccadilly (MAN) train times
The table below shows live departures for Slough station (SLO) to Manchester Piccadilly (MAN) trains for today, Friday 20 March. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
G24245+ Tube from London Paddington to London Kings Cross+ C40872+ Y25831 | 22:08 Slough station (SLO) | 8h41 | 06:49 Manchester Piccadilly (MAN) | 4 changes | |
| Saturday 21 March | |||||
P33120+ Tube from London Paddington to London Euston+ W02609 | 09:02 Slough station (SLO) | 3h17 | 12:19 Manchester Piccadilly (MAN) | 2 changes | |
G24224+ Tube from Tottenham Court Road (Elizabeth line) to London Euston+ W02535 | On time 09:21 Slough station (SLO) | 3h23 | 12:44 Manchester Piccadilly (MAN) | 2 changes | |
L23446+ C72312 | 09:24 Slough station (SLO) | 4h05 | 13:29 Manchester Piccadilly (MAN) | 1 change | |
G24239+ Tube from Tottenham Court Road (Elizabeth line) to London Euston+ W02606 | On time 09:38 Slough station (SLO) | 3h27 | 13:05 Manchester Piccadilly (MAN) | 2 changes | |
P33126+ Tube from London Paddington to London Euston+ W02604 | 10:03 Slough station (SLO) | 3h16 | 13:19 Manchester Piccadilly (MAN) | 2 changes | |
L24015+ Tube from Tottenham Court Road (Elizabeth line) to London Euston+ W02533 | On time 10:21 Slough station (SLO) | 3h23 | 13:44 Manchester Piccadilly (MAN) | 2 changes | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Slough station (SLO) to Manchester Piccadilly (MAN) by train, coach or flight
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
21 Mar
22 Mar
23 Mar
24 Mar
25 Mar
26 Mar
27 Mar
Why should you book Slough station (SLO) to Manchester Piccadilly (MAN) trains with Omio?
Why book with Omio vs CrossCountry?
- Compare with other providers: On Omio, you can not only buy tickets for CrossCountry, but also compare tickets for the likes of Avanti West Coast, Elizabeth Line (TfL) or Great Western Railway (GWR) to find the best option for your trip from Slough station (SLO) to Manchester Piccadilly (MAN).
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare CrossCountry with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Slough station (SLO) to Manchester Piccadilly (MAN).
Why book with Omio over Wanderu or Raileurope?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Avanti West Coast, Elizabeth Line (TfL) or Great Western Railway (GWR) to find the best option for your trip from Slough station (SLO) to Manchester Piccadilly (MAN).
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Slough station (SLO) to Manchester Piccadilly (MAN).
Journey information
Overview: Train from Slough station (SLO) to Manchester Piccadilly (MAN)
Trains from Slough station (SLO) to Manchester Piccadilly (MAN) run on average 8 times per day, taking around 3h 13m. Cheap train tickets for this journey start at £35 but you can travel from only £18 by coach.
The earliest train runs at 06:21, the last at 11:03. The fastest train covers the 245 km distance in 3h 16m.
Distance 245 km |
Average train duration 3h 13m |
Cheapest ticket price £35 |
Trains per day 8 |
Fastest train 3h 16m |
First train 06:21 |
Last train 11:03 |
Train companies: CrossCountry, Avanti West Coast, Elizabeth Line (TfL), Great Western Railway (GWR) from Slough station (SLO) to Manchester Piccadilly (MAN) trainsCrossCountry, Avanti West Coast, Elizabeth Line (TfL), Great Western Railway (GWR) trains will get you between Slough station (SLO) and Manchester Piccadilly (MAN) from £18. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
CrossCountry
Avanti West Coast
Elizabeth Line (TfL)
Great Western Railway (GWR)
FAQs: Slough station (SLO) to Manchester Piccadilly (MAN) train
Find answers to the most common questions about traveling from Slough station (SLO) to Manchester Piccadilly (MAN) by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Manchester Piccadilly (MAN), this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Slough station (SLO) and Manchester Piccadilly (MAN)
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- The car park is open 24/7. Access is via Brunel Way.
- The Moon and Spoon
- The Red Lion
- Outside the main entrance.
- Elevators, ramps.
- £0.50
- Holiday Inn Slough - Windsor
- Moxy Slough
- Travelodge Slough
- Located in the main hall
- 36 places, covered
- Enterprise
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for trains to London and Reading
- Hall 2: ticket office and waiting area
- Train: Great Western Railway services
- Bus: Several local bus services available
- Mon - Sat: 04:30 - 22:30
- Sun: 07:00 - 22:30
- Pay as you go Wi-Fi is available through BT Wi-Fi.
- Operated by Excess Baggage Co. Llocated between Platforms 10 and 11 and open daily from 08:00 to 21:00.
- Burger King
- Caffè Nero
- Carluccio’s
- Hotel Chocolat
- Starbucks
- The Pasty Shop
- Costa Coffee
- Pret a Manger
- Upper Crust
- McDonald's
- & more
- There is step-free access throughout the station. Ramps for train access and wheelchairs are also available.
- DoubleTree by Hilton Hotel Manchester - Piccadilly
- Premier Inn Manchester City
- Staycity Aparthotels - Manchester Piccadilly
- Mon - Sat: 04:30 - 22:30
- Sun: 07:00 - 22:30
- Located near the Fairfield Street entrance on the mezzanine level.
- Bus lines: 1, 2, 3, 147
- Train lines: Northern, TransPennine Express, Avanti West Coast, CrossCountry, East Midlands Trains, Transport for Wales





