The cheapest and fastest trains from Milan to Isernia
Cheapest price
£40
Average price
£74
Fastest journey
6 h 25 m
Average duration
10 h 2 m
Trains per day
4
Distance
592 km
The best way to find a cheap train ticket from Milan to Isernia is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Milan to Isernia will cost around £74 if you buy it on the day, but you can find cheap train tickets today for only £40.
Of the 4 trains that leave Milan for Isernia every day 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct trains cover the 592 km distance in an average of 10 h 2 m but if you time it right, some trains will get you there in just 6 h 25 m .
The slowest trains will take 12 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.








Travel Information
Compare coach, train and flight for Milan to Isernia
Omio recommends booking the train as it is the most popular option from Milan to Isernia among Omio's users. If you are prioritising price take the coach with prices starting from £31. For those with little time consider booking a flight which can get you there in 1h 13m. The ticket price range depends on the travel mode: a coach costs an average of £31, and a flight costs an average of £23.
Distance: 592 km
Compare train with
Most popular Train | Coach | Flight |
|---|---|---|
£62 Average Price | £53 Average Price Cheapest | £65 Average Price |
9h 29m Average total duration 8h 59m Onboard + 30m Additional time* | 9h 57m Average total duration 9h 27m Onboard + 30m Additional time* | 4h 13m Average total duration Fastest 1h 13m Onboard + 3h 0m Additional time* |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Live departures
Milan to Isernia train times
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
![]() | 03:45 Milan | 11h02 | 14:47 Isernia | 0 changesdirect | |
![]() | 04:40 Milan | 6h41 | 11:21 Isernia | 0 changesdirect | |
![]() | 11:10 Milan | 6h44 | 17:54 Isernia | 0 changesdirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan to Isernia by coach, train or flight
06 Nov
07 Nov
08 Nov
09 Nov
10 Nov
11 Nov
12 Nov
Journey information
Overview: Train from Milan to Isernia
Distance 592 km |
Average train duration 8h 59m |
Cheapest ticket price £33 |
Trains per day 11 |
Fastest train 4h 23m |
First train 04:40 |
Last train 22:45 |
Train companies: Frecciarossa, Italo, Intercity, Intercity Notte from Milan to Isernia trainsFrecciarossa, Italo, Intercity, Intercity Notte trains will get you between Milan and Isernia from £23. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Frecciarossa
Italo
Intercity
Intercity Notte
FAQs: Milan to Isernia train

popular train stations
Important Stations and Airports in Milan and Isernia
- Free Wi-Fi in the station.
- Caffeteria Panni Caldi
- Princi
- Burgez
- Bricco Café
- U! Come tu mi vuoi
- Autogrill
- Culto
- Accessible facilities such as ticket machines, toilets, and ramps and additional assistance as needed from 07:45 to 22:30.
- Hotel NH Milano Palazzo Moscova
- AC Hotel by Marriott Milano
- Tocq Hotel
- Metro lines: M2, M5
- Bus lines: 43, 56, 70, 94
- Train lines: R21, R31, S1, S11, S2, S5, S7, S8
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, 24 hours a day. Access is available from Via G Battista Cassinis.
- Ristorante Pizzeria Il Moro
- Osteria La Piola
- Outside the main entrance.
- Elevators, ramps.
- €1
- Starhotels Business Palace
- Hotel Mistral
- Hotel Brenta Milano
- Located in the main hall
- Avis
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-8 for trains to various destinations
- Hall 2: metro connections
- Metro: Line M3
- Bus: Several lines available
- Train: Regional and high-speed services
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available near the station with access from Via Rombon.
- Ristorante Pizzeria Il Girasole
- Osteria Lambrate
- Outside the main entrance.
- Elevators, ramps.
- €1
- MEININGER Milano Lambrate
- Hotel Gamma
- Hotel Lugano
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-7 for trains to various destinations
- Hall 2: Metro connections
- Metro: Line M2
- Bus: Several lines available
- Tram: Line 19
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- Parking is available 24/7 with access from Via Giovanni XXIII.
- Pasta e Pizza
- Ristorante da Adriano
- Outside the main entrance.
- Ramps.
- €0.50
- Grand Hotel Europa
- Hotel Ristorante Sayonara
- Hotel La Tequila
- Located in the main hall
- Located in the main hall
- Free
- Hall 1: main entrance, ticket office, and waiting area
- Hall 2: platforms for regional trains
- Bus: Several local lines available
- Train: Regional connections
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