2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest trains from Mainz to Prague
Showing times and prices for 16 Apr
Cheapest price
£143
Average price
£181
Fastest journey
8 h 19 m
Average duration
8 h 52 m
Trains per day
5
Distance
439 km
Cheap tickets
The best way to find a cheap train ticket from Mainz to Prague is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Mainz to Prague will cost around £181 if you buy it on the day, but you can find cheap train tickets today for only £143.
Fast trains
To travel from Mainz to Prague you need to make at least 2 changes.
S8 · ICE 527 · 3565+
3578:028h19Mainz Hbf16:21Prague hlavní nádraží£1431One-way3 changes- S8 · ICE 621 · 3569+35910:028h19Mainz Hbf18:21Prague hlavní nádraží£1431One-way3 changes
- 29247 · ICE 2507 · BUS 10383 · RJ 3838:278h58Mainz Hbf17:25Prague hlavní nádraží£1681One-way3 changes
- 4257 · ICE 2509 · RJ 17710:109h05Mainz Hbf19:15Prague-Holešovice£1681One-way2 changes
ICE 1648 · ICE 513 · EC 3598:429h39Mainz Hbf18:21Prague hlavní nádraží£2841One-way2 changes
- S8 · ICE 527 · 3565+3578:028h19Mainz Hbf16:21Prague hlavní nádraží£1431One-way3 changes
- S8 · ICE 621 · 3569+35910:028h19Mainz Hbf18:21Prague hlavní nádraží£1431One-way3 changes
- 29247 · ICE 2507 · BUS 10383 · RJ 3838:278h58Mainz Hbf17:25Prague hlavní nádraží£1681One-way3 changes
- 4257 · ICE 2509 · RJ 17710:109h05Mainz Hbf19:15Prague-Holešovice£1681One-way2 changes
- ICE 1648 · ICE 513 · EC 3598:429h39Mainz Hbf18:21Prague hlavní nádraží£2841One-way2 changes
Travel Information
Compare coach, train and flight for Mainz to Prague
Omio recommends booking the train as it is the most popular option from Mainz to Prague among Omio's users. If you are prioritising price take the coach with prices starting from £24. For those with little time consider booking a flight which can get you there in 1h 29m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a coach costs an average of £24, and a flight costs an average of £73.
Distance: 439 km
Compare train with
Most popular Train | Coach | Flight |
|---|---|---|
£79 Average Price | £35 Average Price Cheapest | £149 Average Price |
9h 5m Average total duration 8h 35m Onboard + 30m Additional time* | 7h 40m Average total duration 7h 10m Onboard + 30m Additional time* | 4h 29m Average total duration Fastest 1h 29m Onboard + 3h 0m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions | 1.3 - 2.6kg CO2 emissions |
Most popular train company |  Most popular bus company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Mainz to Prague train times
The table below shows live departures for Mainz to Prague trains for tomorrow, Wednesday 15 April. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
| S8 · ICE 527 · 3565+357 | 6:02 Mainz Hbf | 8h19 | 14:21 Prague hlavní nádraží | 3 changes | |
| 29247 · ICE 2507 · BUS 10383 · RJ 383 | 6:27 Mainz Hbf | 8h58 | 15:25 Prague hlavní nádraží | 3 changes | |
| ICE 1648 · ICE 513 · EC 359 | On time 6:42 Mainz Hbf | 9h39 | 16:21 Prague hlavní nádraží | 2 changes | |
| S8 · ICE 621 · 3569+359 | 8:02 Mainz Hbf | 8h19 | 16:21 Prague hlavní nádraží | 3 changes | |
| 4257 · ICE 2509 · RJ 177 | On time 8:10 Mainz Hbf | 9h05 | 17:15 Prague-Holešovice | 2 changes |
Find all the dates and times for this journey
Compare prices and tickets Mainz to Prague by coach, train or flight
Compare coach, train and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Thu
16 Apr
16 Apr
Fri
17 Apr
17 Apr
Sat
18 Apr
18 Apr
Sun
19 Apr
19 Apr
Mon
20 Apr
20 Apr
Tue
21 Apr
21 Apr
Wed
22 Apr
22 Apr
Thu
23 Apr
23 Apr
Fri
24 Apr
24 Apr
Sat
25 Apr
25 Apr
Sun
26 Apr
26 Apr
Mon
27 Apr
27 Apr
Tue
28 Apr
28 Apr
Wed
29 Apr
29 Apr
Why should you book Mainz to Prague trains with Omio?
Deutsche Bahn as well as alex-Länderbahn und Vogtlandbahn-GmbH or České dráhy offer trains services from Mainz to Prague.
Omio is an official ticket reseller for all your travel options from Mainz to Prague.
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of alex-Länderbahn und Vogtlandbahn-GmbH or České dráhy to find the best option for your trip from Mainz to Prague.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Mainz to Prague.
Why book with Omio over Trainline, Wanderu or Raileurope?
- Compare with other providers: On Omio, you can also compare tickets for the likes of alex-Länderbahn und Vogtlandbahn-GmbH or České dráhy to find the best option for your trip from Mainz to Prague.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Mainz to Prague.
Journey information
Overview: Train from Mainz to Prague
Germany
Czechia
Trains from Mainz to Prague run on average 9 times per day, taking around 8h 35m. Cheap train tickets for this journey start at £28 but you can travel from only £24 by coach.
The earliest train runs at 00:30, the last at 23:50. The fastest train covers the 439 km distance in 7h 41m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Coach from £24
Distance 439 km |
Average train duration 8h 35m |
Cheapest ticket price £28 |
Trains per day 9 |
Fastest train 7h 41m |
First train 0:30 |
Last train 23:50 |
Cheapest Month Jan |
Cheapest Day Tue |
High Season Jul - Sept |
Low Season Apr - Jun |
Busiest Day Sat |
Least Busy Day Mon |
Best time to book 5 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Coach from £24
Train companies: Deutsche Bahn, alex-Länderbahn und Vogtlandbahn-GmbH, České dráhy from Mainz to Prague trainsDeutsche Bahn, alex-Länderbahn und Vogtlandbahn-GmbH, České dráhy trains will get you between Mainz and Prague from £24. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
About
Deutsche Bahn (DB) is Germany’s main train operator, running around 40,000 domestic and international services each day. Its fleet includes a variety of train types: high-speed ICE (Intercity Express) trains, reaching up to 300 km/h; IC (Intercity) and EC (EuroCity) trains for long-distance travel; and IRE (Interregio-Express), RE (Regional Express), and RB (Regionalbahn) services for regional and local connections. While bathrooms are standard on all trains, amenities such as onboard restaurants and free Wi-Fi are available only on certain train types and routes. DB offers a wide range of fares, including Super Saver, Saver, and Flexible tickets, along with discount cards like the BahnCard 25, 50, and 100. Additional options include single tickets, day tickets, and group tickets. Popular routes include Berlin–Munich, Hamburg–Frankfurt, Cologne–Stuttgart, Berlin–Dresden, and Hamburg–Cologne, as well as numerous regional services across Germany.
Luggage & cancellation policy
Average Duration
8h 14m
Cheapest Price
£45
Luggage included
Passengers are allowed to bring hand luggage and one additional larger item free of charge, provided they can carry it themselves
Luggage storage
Luggage can be stored in overhead racks, under the seat, or in designated luggage areas near the doors or in the middle of the carriage.
Cancellation Policy
Tickets can be canceled based on their fare conditions as mentioned in what type of train tickets are refundable?
Refund
If DB cancels a train, passengers are entitled to a full refund of the ticket price.
Amenities on board the train
Wifi
Food sold onboard
Most ICE and many IC/EC trains have:
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Seat reservation
Second Class:
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Toilets
USB plugs
Accessibility
DB trains are equipped with facilities for passengers with reduced mobility, including wheelchair spaces, accessible restrooms, and assistance services.
Pets
Small pets (e.g. cats, small dogs, etc.):
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Quiet zone
alex-Länderbahn und Vogtlandbahn-GmbH
About
agilis is a railway company operating regional trains based in Regensburg in Bavaria since 2010. It operates in the German state of Bavaria connecting cities like Ulm, Ingolstadt, Regensburg and Plattling. They offer single tickets and comfortable trains with some popular routes covering Ulm to Regensburg, Neumarkt to Passau and Ingolstadt to Plattling.
Luggage & cancellation policy
alex-Länderbahn und Vogtlandbahn-GmbH frequency
3 a day
Luggage included
One piece of hand luggage and one larger piece included
Luggage storage
Overhead racks and designated luggage areas
Cancellation Policy
Cancellation possible according to fare conditions
Refund
Full refund for canceled services
Amenities on board the train
Wifi
Food sold onboard
Snack and beverage service available on some routes
Seat reservation
Seat reservations available for additional fee
Toilets
USB plugs
Accessibility
Wheelchair spaces available, assistance for boarding/alighting
Pets
Small pets in carriers travel free, larger dogs require ticket and muzzle
Quiet zone
České dráhy
About
Czech Railways (České dráhy, ČD) is the largest railway company in the Czech Republic, connecting major cities, small towns, and even international destinations across Europe. Its extensive fleet of modern trains ranges from comfortable regional services with A/C and onboard WiFi to high-speed trains offering dining cars, power outlets, and premium seating for long-distance journeys. Czech Railways combines affordability and convenience, making it a popular choice for travelers exploring the Czech Republic and beyond.
Luggage & cancellation policy
Average Duration
7h 41m
Cheapest Price
£58
Luggage included
You can transport briefcases, laptops, rucksacks, trolley bags and suitcases on board at no charge.
Additional luggage
Items of luggage must not be so big or heavy that they cannot be carried by a single person, with a generous maximum size of 90 x 60 x 40 cm and a maximum weight of 50kg.
Luggage storage
Luggage can be stored above or below the seat, on the passenger's lap, or in special luggage racks in certain carriages.
Cancellation Policy
Tickets purchased online can be returned free of charge up to 15 minutes before the train's departure.
Refund
If a train is completely canceled, booking fees are refundable, and compensation may be due directly from the rail operator.
Pregnant on board
Being pregnant on board is allowed.
Unaccompagned minor
Automatic compensation for online ČD domestic tickets applies if the system registers a delay of more than 60 minutes at the destination and the ticket was checked by the conductor.
Amenities on board the train
Food sold onboard
A hearty breakfast is included in the ticket price for sleeper carriage services.
Seat reservation
Seat reservations are included with tickets and adjacent seats are booked wherever possible.
Accessibility
Czech Railways is continuously expanding its fleet of wheelchair-accessible carriages and offers assistance for passengers with limited mobility.
Pets
Small pets are allowed on board, but cannot be transported in 1st class, restaurant, or bistro cars.
FAQs: Mainz to Prague train
Find answers to the most common questions about traveling from Mainz to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.
The cost of a train ticket from Mainz to Prague can vary. The cheapest tickets are usually available from £28, while the average price tends to be around £79.
The train journey from Mainz to Prague covers a distance of 439 km and takes approximately 7h 41m. Trains run 9 per day.
The train distance from Mainz to Prague is 439 km.
The first train from Mainz to Prague leaves at 0:30.
The last train from Mainz to Prague departs at 23:50.
Trains from Mainz to Prague run approximately 9 times per day.
Unfortunately, there is no direct train service currently available from Mainz to Prague.
To get from Mainz to Prague, you can choose from several travel options including coach, train and flight.
There is no night train service from Mainz to Prague.
The train station in Mainz that goes to Prague is Mainz Hbf, and it arrives at Prague hlavní nádraží.
The cheapest way to get from Mainz to Prague is by coach, costing approximately £24.
Booking trains from Mainz to Prague in advance is advisable, especially during peak travel seasons or for long journeys, to ensure availability and secure better fares.
The train journey from Mainz to Prague is indeed scenic, offering views of the Rhine Valley, rolling hills, and picturesque villages, especially as it passes through regions such as the Upper Middle Rhine Valley, a UNESCO World Heritage site.
A day trip from Mainz to Prague is not feasible as the journey takes 7h 41m. There are 8 trains per day for this route, covering a distance of 439 km.
Discover Prague by climbing Petrin Hill for stunning city views and exploring the Petrin Tower and Mirror Maze. Experience the vibrant nightlife in Vinohrady, or enjoy a boat cruise on the Vltava River for a unique perspective of the city's landmarks. Immerse yourself in Czech history at the National Museum, and attend a classical music concert in one of its historic churches or concert halls. Visit iconic sights such as Prague Castle, Charles Bridge, Old Town Square, St. Vitus Cathedral, and the Jewish Quarter to fully appreciate the city's rich heritage and architectural beauty.
Typically, spending three to four days in Prague allows visitors to explore its main attractions, such as Prague Castle, Charles Bridge, and the Old Town Square, while also enjoying the local cuisine and culture.
Yes, you can take the train from Mainz to Prague.
popular train stations
Important Stations and Airports in Mainz and Prague
Mainz
Prague
The major train station for departures in Mainz is Mainz Hbf. Find all the information you need to know about services, amenities and connections at Mainz Hbf for your trip from Mainz to Prague.
Amenities at train station
Wifi
Lockers
Shopping
Parking
Dining
ATM
Taxis
Accessibility
WC
Hotel
Lounge
Lost and Found Office
Ticket Office
Bike Parking
Bike Rental
Car Rental
Information Deskinformation
Ticket Office Hours
- Monday: 06:00 - 21:15
- Tuesday: 06:00 - 21:15
- Wednesday: 06:00 - 21:15
- Thursday: 06:00 - 21:15
- Friday: 06:00 - 21:15
- Saturday: 07:00 - 19:00
- Sunday: 08:00 - 20:00
Distance to city center
2 kmDining
- Mangal
- Asia Wok
- Bistrorante Midi
- McDonald's
Hotel
- Advena Europa Hotel
- GuestHouse Mainz
- Terminus
- Hotel Moguntia
Amenities at train station
WifiLockersShoppingParkingDiningATMTaxisAccessibilityWCHotelLoungeLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation Deskinformation
Distance to city center
1 kmDining
- McDonald's
- Cafe Extrablatt
- Hans im Glück
- The Big Easy
Hotel
- Hyatt Regency Mainz
- Favorite Parkhotel
- Ibis Hotel Mainz City
- Hof Ehrenfels
Mainz-Laubenheim
Amenities at train station
WifiLockersShoppingParkingDiningATMTaxisAccessibilityWCHotelLoungeLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation Deskinformation
Distance to city center
3 kmDining
- Zum Laubenheimer Ried - Da Giovanni
- Mainzer Hof
- Pizza Roma
- Bäckerei Werner
Hotel
- Goldene Ente
The major train station for arrivals in Prague is Praha hlavní nádraží. Find all the information you need to know about services, amenities and connections at Praha hlavní nádraží for your journey to Prague from Mainz.
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotel
ShowerLoungeLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation Desk
Luggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 10:00 PM Monday - Sunday
Distance to city center
1 km
Number of platforms
7Wifi
- Free
Parking
- The car park is open 7 days a week, 24 hours a day. Access via Wilsonova Street.
Dining
- Restaurant Fantova Kavárna
- Sushi Time
Taxis
- Outside the main entrance.
Accessibility
- Elevators, ramps.
WC
- CZK 10
Hotel
- Hotel Esplanade Prague
- Falkensteiner Hotel Maria Prag
- Hotel City Central
Shower
- Cost CZK 100
Lounge
- Located in the main hall
Lost and Found Office
- Located in the main hall
Car Rental
- Avis
- Europcar
- Hertz
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, platform 1-7 for trains to Germany, Austria, Slovakia, and regional destinations
- Hall 2: Metro connections
Public transport options for Praha hlavní nádraží
- Metro: Line C
- Tram: Lines 5, 9, 26
- Bus: Several lines available
Praha Masarykovo Nádraží
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation DeskLuggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 10:00 PM Monday - Sunday
Number of platforms
5Wifi
- Free
Parking
- Parking is available nearby with several public parking options.
Dining
- Restaurant Kotleta
- Café Imperial
Taxis
- Outside the main entrance.
Accessibility
- Ramps.
WC
- CZK 10
Hotel
- Hotel Kings Court
- Grand Hotel Bohemia
- Hotel Paris Prague
Lost and Found Office
- Located in the main hall
Car Rental
- Avis
- Europcar
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, platform 1-5 for regional and suburban trains
Public transport options for Praha Masarykovo Nádraží
- Metro: Line B
- Tram: Lines 3, 5, 14, 24
- Bus: Several lines available
Praha-Holesovice
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation DeskLuggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 10:00 PM Monday - Sunday
Distance to city center
2 kmNumber of platforms
4Wifi
- Free
Parking
- Parking is available 24/7 with access from Partyzánská street.
Dining
- Restaurant Na Kovárně
- Cross Club
Taxis
- Outside the main entrance.
Accessibility
- Ramps, restrooms.
WC
- CZK 10
Hotel
- Mama Shelter Prague
- Plaza Alta Hotel
- Hotel Belvedere
Lost and Found Office
- Located in the main hall
Car Rental
- Avis
- Budget
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, platform 1-4 for trains to Germany, Austria, and regional destinations
- Hall 2: ticket office and waiting area
Public transport options for Praha-Holesovice
- Metro: Line C
- Tram: Lines 6, 12, 17
- Bus: Several lines available
Most popular train connections from Mainz
More options for your journey from Mainz to Prague
Here are some other resources that might have the information you need
Most popular trains to and from Prague and Mainz
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
