The cheapest and fastest trains from Mainz to Brussels
Cheapest price
£108
Average price
£148
Fastest journey
5 h 3 m
Average duration
5 h 34 m
Trains per day
8
Distance
295 km
The best way to find a cheap train ticket from Mainz to Brussels is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Mainz to Brussels will cost around £148 if you buy it on the day, but you can find cheap train tickets today for only £108.
To travel from Mainz to Brussels you need to make at least one change.
29510 · 25420 · IC 2202 · ICE 3148:536h42Mainz Hbf15:35Brussels-Midi£1081One-way3 changes
29558 · 4254 · ICE 1020 · ICE 3149:276h08Mainz Hbf15:35Brussels-Midi£1271One-way3 changes
S8 · ICE 168:325h03Mainz Hbf13:35Brussels-Midi£1371One-way1 change
S8 · ICE 614 · ICE 168:325h03Mainz Hbf13:35Brussels-Midi£1501One-way2 changes
4255 · ICE 820 · S19 · ICE 3148:107h25Mainz Hbf15:35Brussels-Midi£1511One-way3 changes
S8 · ICE 168:325h03Mainz Hbf13:35Brussels-Midi£1371One-way1 change
S8 · ICE 614 · ICE 168:325h03Mainz Hbf13:35Brussels-Midi£1501One-way2 changes
S8 · ICE 31410:325h03Mainz Hbf15:35Brussels-Midi£1691One-way1 change
29558 · 4254 · ICE 1020 · ICE 3149:276h08Mainz Hbf15:35Brussels-Midi£1271One-way3 changes
S8 · ICE 128 · ICE 3149:026h33Mainz Hbf15:35Brussels-Midi£1701One-way2 changes
Travel Information
Compare coach, train and flight for Mainz to Brussels
Omio recommends booking the train as it is the most popular option from Mainz to Brussels among Omio's users. If you are prioritising price take the coach with prices starting from £21. For those with little time consider booking a flight which can get you there in 1h 0m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a coach costs an average of £21, and a flight costs an average of £119.
Distance: 295 km
Compare train with
Most popular Train | Coach | Flight |
|---|---|---|
£93 Average Price | £29 Average Price Cheapest | £272 Average Price |
4h 13m Average total duration 3h 43m Onboard + 30m Additional time* | 5h 58m Average total duration 5h 28m Onboard + 30m Additional time* | 4h 0m Average total duration Fastest 1h 0m Onboard + 3h 0m Additional time* |
0.1 - 0.3kg CO2 emissions Lowest | 0.3 - 0.7kg CO2 emissions | 0.9 - 1.8kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Mainz to Brussels train times
The table below shows live departures for Mainz to Brussels trains for tomorrow, Sunday 31 May. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
4255 · ICE 820 · S19 · ICE 314 | On time 8:10 Mainz Hbf | 7h25 | 15:35 Brussels-Midi | 3 changes | |
S8 · ICE 614 · ICE 314 | On time 8:32 Mainz Hbf | 7h03 | 15:35 Brussels-Midi | 2 changes | |
S8 · ICE 16 | On time 8:32 Mainz Hbf | 5h03 | 13:35 Brussels-Midi | 1 change | |
S8 · ICE 614 · ICE 16 | On time 8:32 Mainz Hbf | 5h03 | 13:35 Brussels-Midi | 2 changes | |
29510 · 25420 · IC 2202 · ICE 314 | On time 8:53 Mainz Hbf | 6h42 | 15:35 Brussels-Midi | 3 changes | |
S8 · ICE 128 · ICE 314 | On time 9:02 Mainz Hbf | 6h33 | 15:35 Brussels-Midi | 2 changes | |
29558 · 4254 · ICE 1020 · ICE 314 | On time 9:27 Mainz Hbf | 6h08 | 15:35 Brussels-Midi | 3 changes | |
S8 · ICE 314 | On time 10:32 Mainz Hbf | 5h03 | 15:35 Brussels-Midi | 1 change | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mainz to Brussels by coach, train or flight
Compare coach, train and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
31 May
01 Jun
02 Jun
03 Jun
04 Jun
05 Jun
06 Jun
Why should you book Mainz to Brussels trains with Omio?
Why book with Omio vs Deutsche Bahn?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Mainz to Brussels.
Why book with Omio over Trainline or Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Mainz to Brussels.
Journey information
Overview: Train from Mainz to Brussels
Trains from Mainz to Brussels run on average 5 times per day, taking around 3h 43m. Cheap train tickets for this journey start at £48 but you can travel from only £21 by coach.
The earliest train runs at 00:20, the last at 23:48. The fastest train covers the 295 km distance in 3h 33m.
Distance 295 km |
Average train duration 3h 43m |
Cheapest ticket price £48 |
Trains per day 5 |
Fastest train 3h 33m |
First train 0:20 |
Last train 23:48 |
Cheapest Month Feb |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Fri |
Best time to book 1 day |
Train companies: Deutsche Bahn from Mainz to Brussels trainsDeutsche Bahn trains will get you between Mainz and Brussels from £21. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
FAQs: Mainz to Brussels train
Find answers to the most common questions about traveling from Mainz to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Mainz and Brussels
- Monday: 06:00 - 21:15
- Tuesday: 06:00 - 21:15
- Wednesday: 06:00 - 21:15
- Thursday: 06:00 - 21:15
- Friday: 06:00 - 21:15
- Saturday: 07:00 - 19:00
- Sunday: 08:00 - 20:00
- Mangal
- Asia Wok
- Bistrorante Midi
- McDonald's
- Advena Europa Hotel
- GuestHouse Mainz
- Terminus
- Hotel Moguntia
- McDonald's
- Cafe Extrablatt
- Hans im Glück
- The Big Easy
- Hyatt Regency Mainz
- Favorite Parkhotel
- Ibis Hotel Mainz City
- Hof Ehrenfels
- Pizzeria Venezia
- Kaiser Pide & Kebaphaus
- Alaaeddin Döner
- Super 8 by Wyndham Mainz Zollhafen
- Mon - Sun: 05:45 - 21:30
- Wi-Fi is available for a fee.
- Baggage storage facility is located across from the Thalys business lounge.
- Pullman Hotel Bar
- Quick Gare du Midi
- Subway
- EXKi Zuid
- Starbucks
- Häagen-Dazs
- Sbarro
- The Coffee Club
- The Belgian Chocolate House
- PAUL
- & many more
- Station has a wide range of facilities for passengers with reduced mobility: elevators and escalators to all platforms, wheelchair lifts and mobile ramps, disabled toilet and parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
- Les Lofts De Styliste
- Park Inn by Radisson Brussels Midi
- Pullman Brussels Centre Midi
- Located in the main concourse and next to the international platforms.
- Mon - Sun: 06:15 - 22:00
- Free Wi-Fi available in Starbucks.
- Luggage lockers are located on Level 0 near Platforms 1 and 2.
- Starbucks
- Brasserie 28 Brewery
- Panos
- Delitraiteur Eat & Go
- Station has a wide range of facilities for passengers with limited mobility: elevators and escalators to platforms, wheelchair lifts and mobile ramps, barrier-free toilets and accessible parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
- Hilton Brussels Grand Palace
- Hotel NH Brussels Carrefour de l'Europe
- Hôtel The Moon
- Mon - Sun: 06:15 - 22:00
- Travel Center / information desk is located on the left side from the main entrance.
- Metro lines: 1, 5
- Train lines: IC, Intercity Direct 9200, RER (S1, S2, S3, S6, S8, S10)
- 6:30 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week. Access is available via Rue du Progrès.
- Chabrol Brasserie
- Winok Café
- Félix Wine Bar
- Outside the main entrance.
- Elevators, ramps.
- €0.50
- Hotel Progress
- Hilton Brussels City
- Hotel Siru
- Located in the main hall
- Avis
- Europcar
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-6 for international and intercity trains
- Hall 2: platform 7-12 for regional and local trains
- Metro: Line 3, Line 4
- Tram: Line 25, Line 55
- Bus: Several lines available
Most popular train connections from Mainz
More options for your journey from Mainz to Brussels
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