- Must visit
Saint Louis Art Museum
Leading art museum with collections from antiquity to modern works, set within Forest Park.
Cheapest price
£40
Average price
£58
Fastest journey
4 h 46 m
Average duration
5 h 1 m
Trains per day
6
Distance
419 km
The best way to find a cheap train ticket from Chicago, IL to St. Louis, MO is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Chicago, IL to St. Louis, MO will cost around £58 if you buy it on the day, but you can find cheap train tickets today for only £40.
Of the 6 trains that leave Chicago, IL for St. Louis, MO every day 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct trains cover the 419 km distance in an average of 5 h 1 m but if you time it right, some trains will get you there in just 4 h 46 m .
The slowest trains will take 5 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
307 Lincoln Service
301 Lincoln Service
319 Lincoln Service Missouri River Runner
305 Lincoln Service
21 Texas Eagle
301 Lincoln Service
307 Lincoln Service
319 Lincoln Service Missouri River Runner
305 Lincoln Service
21 Texas EagleOmio recommends booking the train as it is the most popular option from Chicago, IL to St. Louis, MO among Omio's users. If you are prioritising price take the train with prices starting from £22. For those with little time consider booking a flight which can get you there in 1h 22m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a train costs an average of £22, and a flight costs an average of £45.
Distance: 419 km
Most popular Train | Coach | Flight |
|---|---|---|
£38 Average Price Cheapest | £41 Average Price | £199 Average Price |
5h 30m Average total duration 5h 0m Onboard + 30m Additional time* | 7h 3m Average total duration 6h 33m Onboard + 30m Additional time* | 4h 22m Average total duration Fastest 1h 22m Onboard + 3h 0m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.0kg CO2 emissions | 1.3 - 2.5kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The table below shows live departures for Chicago, IL to St. Louis, MO trains for today, Friday 21 August. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
305 Lincoln Service | 17:20 Chicago Union Station, Chicago, IL | 5h03 | 22:23 St. Louis Station, St. Louis, MO | 0 changesdirect | |
59 City Of New Orleans · 8358 AMTRAK | 18:05 Chicago Union Station, Chicago, IL | 9h25 | 3:30 St. Louis Station, St. Louis, MO | 1 change | |
307 Lincoln Service | 19:10 Chicago Union Station, Chicago, IL | 4h59 | 0:09 St. Louis Station, St. Louis, MO | 0 changesdirect | |
| Saturday 22 August | |||||
301 Lincoln Service | 7:15 Chicago Union Station, Chicago, IL | 4h46 | 12:01 St. Louis Station, St. Louis, MO | 0 changesdirect | |
319 Lincoln Service Missouri River Runner | 9:50 Chicago Union Station, Chicago, IL | 5h01 | 14:51 St. Louis Station, St. Louis, MO | 0 changesdirect | |
21 Texas Eagle | 14:10 Chicago Union Station, Chicago, IL | 5h15 | 19:25 St. Louis Station, St. Louis, MO | 0 changesdirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Chicago, IL to St. Louis, MO run on average 6 times per day, taking around 5h 0m. Cheap train tickets for this journey start at £22 if you book in advance.
There are 5 trains per day. The earliest train runs at 04:30, the last at 23:45. The fastest train covers the 419 km distance in 3h 57m.
Distance 419 km |
Average train duration 5h 0m |
Cheapest ticket price £22 |
Trains per day 6 |
Direct trains 5 |
Fastest train 3h 57m |
First train 4:30 |
Last train 23:45 |
Cheapest Month Jun |
Cheapest Day Tue |
High Season Jul - Sept |
Low Season Oct - Dec |
Busiest Day Fri |
Least Busy Day Tue |
Best time to book 91 days |
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
Leading art museum with collections from antiquity to modern works, set within Forest Park.
Engaging museum on American history and culture through objects, stories, and changing exhibitions.
Science museum with hands-on exhibits, planetarium programmes, and family-friendly displays across several halls.
Large urban park with museums, lakes, trails, and major cultural attractions, ideal for a full day outdoors.
Extensive botanical garden with themed landscapes, seasonal displays, and quiet walking paths.
Historic cobbled riverfront area with galleries, shops, and preserved buildings that reflect early St. Louis.
St. Louis-style pizza has a very thin cracker-like base and Provel cheese. It is a long-standing local favourite distinct from deep-pan styles.
Toasted ravioli are breaded ravioli, usually meat-filled, then fried and served with tomato sauce. They are closely associated with The Hill in St. Louis.
Gooey butter cake is a rich local bake with a dense cake base and sweet buttery topping. It originated in St. Louis and remains a classic treat.
Historic deli known for hot salami sandwiches and a lively old-school atmosphere in Midtown.
Popular barbecue spot serving pork steaks, ribs and smoked meats in a relaxed, bustling setting.
Refined dining room offering seasonal American tasting menus and polished service in an elegant Central West End setting.
Moderate for a large US city. Hotels are often cheaper than coastal hubs, while dining and local transport remain manageable for most visitors.
Tip 18-20% in restaurants, more for excellent service. Taxis usually get 10-15%. Round up or leave $1-2 in cafés, depending on service.
Find answers to the most common questions about traveling from Chicago, IL to St. Louis, MO by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most Chicago, IL to St. Louis, MO trains use the Union Station to St. Louis Station station pair. Use this guide to compare Chicago, IL and St. Louis, MO train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Union Station is 3 km from Chicago city centre. Public transport options include:
Union Station has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk and Luggage Carts.
Food options include: The Chicago Firehouse Restaurant, Lou Mitchell's
Free. ATMs are available in the train station.
Ticket office support is available at Union Station. Information desks are located in the main hall.
Luggage storage is available at Union Station. Lost and found is available at the station.
Available at Union Station: Parking, Taxis, WC.
Available at Union Station: Bike Parking, Car Rental.
Accessibility facilities are available at Union Station: Elevators, ramps, restrooms.
Nearby hotels include The Kimpton Gray Hotel, JW Marriott Chicago, W Chicago - City Center.
St. Louis Station has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk and Luggage Carts.
Food options include: Landry's Seafood House, The Station Grille
Free. ATMs are available in the train station.
Ticket office support is available at St. Louis Station. Information desks are located in the main hall.
Luggage storage is available at St. Louis Station. Lost and found is available at the station.
Available at St. Louis Station: Parking, Taxis, WC.
Available at St. Louis Station: Bike Parking, Car Rental.
Accessibility facilities are available at St. Louis Station: Ramps, restrooms.
Nearby hotels include St. Louis Union Station Hotel, Curio Collection by Hilton, Courtyard St. Louis Downtown West, Drury Inn St. Louis at Union Station.
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