- Must visit
Saint Louis Art Museum
Leading art museum with collections from antiquity to modern works, set within Forest Park.




Omio recommends booking the train as it is the most popular option from Milwaukee, WI to St. Louis, MO among Omio's users. If you are prioritising price take the coach with prices starting from £31. For those with little time consider booking a flight which can get you there in 4h 58m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a coach costs an average of £31, and a flight costs an average of £72.
Distance: 527 km
Most popular Train | Coach | Flight |
|---|---|---|
£64 Average Price | £60 Average Price Cheapest | £206 Average Price |
7h 5m Average total duration 6h 35m Onboard + 30m Additional time* | 9h 20m Average total duration 8h 50m Onboard + 30m Additional time* | 7h 58m Average total duration Fastest 4h 58m Onboard + 3h 0m Additional time* |
0.2 - 0.5kg CO2 emissions Lowest | 0.5 - 1.3kg CO2 emissions | 1.6 - 3.2kg CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The table below shows live departures for Milwaukee, WI to St. Louis, MO trains for today, Monday 3 August. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
332 Hiawatha Service · 21 Texas Eagle | 8:05 Milwaukee Intermodal Station, Milwaukee, WI | 11h20 | 19:25 St. Louis Station, St. Louis, MO | 1 change | |
332 Hiawatha Service · 21 Texas Eagle | 8:15 Airport Amtrak Station, Milwaukee, WI | 11h10 | 19:25 St. Louis Station, St. Louis, MO | 1 change | |
334 Hiawatha Service · 21 Texas Eagle | 11:00 Milwaukee Intermodal Station, Milwaukee, WI | 8h25 | 19:25 St. Louis Station, St. Louis, MO | 1 change | |
334 Hiawatha Service · 21 Texas Eagle | 11:10 Airport Amtrak Station, Milwaukee, WI | 8h15 | 19:25 St. Louis Station, St. Louis, MO | 1 change | |
338 Hiawatha Service · 307 Lincoln Service | 15:00 Milwaukee Intermodal Station, Milwaukee, WI | 9h09 | 0:09 St. Louis Station, St. Louis, MO | 1 change | |
338 Hiawatha Service · 307 Lincoln Service | 15:10 Airport Amtrak Station, Milwaukee, WI | 8h59 | 0:09 St. Louis Station, St. Louis, MO | 1 change | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Milwaukee, WI to St. Louis, MO run on average 10 times per day, taking around 6h 35m. Cheap train tickets for this journey start at £39 but you can travel from only £31 by coach.
The earliest train runs at 04:30, the last at 23:00. The fastest train covers the 527 km distance in 7h 23m.
Distance 527 km |
Average train duration 6h 35m |
Cheapest ticket price £39 |
Trains per day 10 |
Fastest train 7h 23m |
First train 4:30 |
Last train 23:00 |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Apr - Jun |
Busiest Day Sat |
Least Busy Day Wed |
Best time to book 91 days |
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
Leading art museum with collections from antiquity to modern works, set within Forest Park.
Engaging museum on American history and culture through objects, stories, and changing exhibitions.
Science museum with hands-on exhibits, planetarium programmes, and family-friendly displays across several halls.
Large urban park with museums, lakes, trails, and major cultural attractions, ideal for a full day outdoors.
Extensive botanical garden with themed landscapes, seasonal displays, and quiet walking paths.
Historic cobbled riverfront area with galleries, shops, and preserved buildings that reflect early St. Louis.
St. Louis-style pizza has a very thin cracker-like base and Provel cheese. It is a long-standing local favourite distinct from deep-pan styles.
Toasted ravioli are breaded ravioli, usually meat-filled, then fried and served with tomato sauce. They are closely associated with The Hill in St. Louis.
Gooey butter cake is a rich local bake with a dense cake base and sweet buttery topping. It originated in St. Louis and remains a classic treat.
Historic deli known for hot salami sandwiches and a lively old-school atmosphere in Midtown.
Popular barbecue spot serving pork steaks, ribs and smoked meats in a relaxed, bustling setting.
Refined dining room offering seasonal American tasting menus and polished service in an elegant Central West End setting.
Moderate for a large US city. Hotels are often cheaper than coastal hubs, while dining and local transport remain manageable for most visitors.
Tip 18-20% in restaurants, more for excellent service. Taxis usually get 10-15%. Round up or leave $1-2 in cafés, depending on service.
Find answers to the most common questions about traveling from Milwaukee, WI to St. Louis, MO by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most Milwaukee, WI to St. Louis, MO trains use the Milwaukee Intermodal Station to St. Louis Station station pair. Use this guide to compare Milwaukee, WI and St. Louis, MO train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Milwaukee Intermodal Station is 1 km from Milwaukee city centre. Public transport options include:
Milwaukee Intermodal Station has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk and Luggage Carts.
Food options include: Milwaukee ChopHouse, The Capital Grille
Free. ATMs are available in the train station.
Ticket office support is available at Milwaukee Intermodal Station. Information desks are located in the main hall.
Luggage storage is available at Milwaukee Intermodal Station. Lost and found is available at the station.
Available at Milwaukee Intermodal Station: Parking, Taxis, WC.
Available at Milwaukee Intermodal Station: Bike Parking, Car Rental.
Accessibility facilities are available at Milwaukee Intermodal Station: Elevators, ramps.
Nearby hotels include Hilton Milwaukee City Center, Hyatt Regency Milwaukee, The Pfister Hotel.
Airport Amtrak Station is 11 km from Milwaukee city centre. Public transport options include:
Airport Amtrak Station has practical services for this route, including Accessibility.
Accessibility facilities are available at Airport Amtrak Station.
St. Louis Station has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk and Luggage Carts.
Food options include: Landry's Seafood House, The Station Grille
Free. ATMs are available in the train station.
Ticket office support is available at St. Louis Station. Information desks are located in the main hall.
Luggage storage is available at St. Louis Station. Lost and found is available at the station.
Available at St. Louis Station: Parking, Taxis, WC.
Available at St. Louis Station: Bike Parking, Car Rental.
Accessibility facilities are available at St. Louis Station: Ramps, restrooms.
Nearby hotels include St. Louis Union Station Hotel, Curio Collection by Hilton, Courtyard St. Louis Downtown West, Drury Inn St. Louis at Union Station.
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