- Must visit
Museo Nacional del Prado
Spain’s premier art museum houses Velázquez, Goya and El Greco masterpieces, making it essential for understanding European painting.
Cheapest price on 15 Oct
£9
Average ticket price on 15 Oct
£41
Fastest journey on 15 Oct
7 h 30 m
Average journey duration on 15 Oct
12 h 28 m
Buses on 15 Oct
5
Distance
492 km
The best way to find a cheap coach ticket from Setúbal to Madrid is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Setúbal to Madrid will cost around £41 if you buy it on the day, but you can find cheap coach tickets today for only £9.
On Thu 15 Oct, we found 5 buses from Setúbal to Madrid, including 2 direct services.
These direct buses cover the 492 km distance in an average of 12 h 28 m but if you time it right, some buses will get you there in just 7 h 30 m .
The slowest buses will take 17 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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FlixBus · FlixBus
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FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBusBuses from Setúbal to Madrid run on average 6 times per day, taking around 10h 5m. Cheap bus tickets for this journey start at £9 if you book in advance.
There are 3 coaches per day. The earliest coach runs at 00:15, the last at 23:25. The fastest coach covers the 492 km distance in 6h 35m.
Distance 492 km |
Average bus duration 10h 5m |
Cheapest ticket price £9 |
Buses per day 6 |
Direct buses 3 |
Fastest bus 6h 35m |
First bus 0:15 |
Last bus 23:25 |
Cheapest Month Oct |
Cheapest Day Sat |
High Season Jul - Sept |
Low Season Jan - Mar |
Busiest Day Sun |
Least Busy Day Mon |
Best time to book 2 days |
The table below shows live departures for Setúbal to Madrid coaches for tomorrow, Thursday 15 October. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 3:50 Setúbal, Interface Transportes | 14h55 | 19:45 Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 1 change | |
FlixBus · FlixBus | 3:50 Setúbal, Interface Transportes | 14h05 | 18:55 Madrid, Estación Sur de Autobuses | 1 change | |
FlixBus · FlixBus · FlixBus | 12:05 Setúbal, Interface Transportes | 17h05 | 6:10 Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 2 changes | |
Normal | 13:45 Setúbal, Terminal Rodoviário de Setúbal TST | 8h44 | 23:29 Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 0 changesdirect | |
Normal | 13:45 Setúbal, Terminal Rodoviário de Setúbal TST | 7h30 | 22:15 Madrid, Estación Sur de Autobuses | 0 changesdirect |
Find all the dates and times for this journey
Discover the best of Madrid — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Madrid trip today.
Spain’s premier art museum houses Velázquez, Goya and El Greco masterpieces, making it essential for understanding European painting.
Madrid’s leading modern art museum is famed for Picasso’s Guernica and strong collections of Dalí, Miró and 20th-century works.
This refined museum features major works by Titian, Rubens and Caravaggio in a manageable collection inside a grand palace.
Madrid’s most famous park offers lakes, gardens, sculptures and broad promenades, perfect for walking, rowing and people-watching.
This grand boulevard links major museums and historic fountains, making it one of the city’s most elegant and culture-rich walks.
A busy central avenue known for theatres, shops and illuminated façades, ideal for architecture, nightlife and classic city views.
A hearty chickpea stew with meats, vegetables and soup, long associated with Madrid taverns and traditional lunchtime dining.
Deep-fried squid rings served in a crusty bread roll, a classic fast bite around Plaza Mayor and one of Madrid’s best-known snacks.
Madrid-style tripe stew with chorizo and morcilla, rich and slow-cooked, traditionally eaten in colder months.
Traditional bar celebrated for excellent tortilla española and honest Madrid-style tapas in a lively, no-frills atmosphere.
Historic tavern famed for roast suckling pig and classic Castilian dishes in an old-fashioned, atmospheric setting near Plaza Mayor.
Iconic churrería serving Madrid’s classic chocolate con churros around the clock in a bustling, traditional setting.
Moderate for Western Europe. Rooms, meals and Metro fares are usually cheaper than Paris or London, but central hotels and popular dining areas raise costs.
Tipping is modest. Round up or leave 5-10% in restaurants for good service. Taxis are usually rounded up. In cafés, leaving small change is enough.
Official public transport app
Estación Sur de Autobuses -> Puerta del Sol, Madrid
The most popular day trips by bus from Madrid are Toledo, Segovia, Ávila, Salamanca and Cuenca. Find out what you can do in these day trip destinations and how to book your bus from Madrid on Omio.

Toledo is a historic hilltop city known for its medieval skyline, cathedral and Christian, Muslim and Jewish heritage. Its winding old streets, stone buildings and Tagus views give it a distinct, time-worn character.
There are 87 coaches per day. The earliest coach runs at 05:15, the last at 23:30. The fastest coach covers the 68 km distance in 50m.

Segovia is known for its Roman aqueduct, the Alcázar and a handsome old town crowned by a grand cathedral. Its Castilian character, historic streets and famous roast suckling pig make it feel elegant yet grounded.
There are 39 coaches per day. The earliest coach runs at 05:35, the last at 23:00. The fastest coach covers the 69 km distance in 1h 20m.

Ávila is best known for its exceptionally well-preserved medieval walls and its strong Castilian character. Granite streets, Romanesque churches and the legacy of Saint Teresa give the city a calm, historic atmosphere.
There are 19 coaches per day. The earliest coach runs at 05:20, the last at 22:00. The fastest coach covers the 88 km distance in 50m.

Salamanca is known for its ancient university, honey-coloured stone and elegant old town. The city feels both scholarly and lively, with historic streets and a strong student presence shaping its character.
There are 25 coaches per day. The earliest coach runs at 05:30, the last at 22:41. The fastest coach covers the 175 km distance in 2h 15m.

Cuenca is known for its Casas Colgadas and its old town set above a dramatic gorge. Medieval streets, a notable cathedral and a calm Castilian atmosphere define its character.
There are 8 coaches per day. The earliest coach runs at 07:00, the last at 22:05. The fastest coach covers the 139 km distance in 2h 0m.
Find answers to the most common questions about traveling from Setúbal to Madrid by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

Most Setúbal to Madrid buses use the Setúbal, Interface Transportes to Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) station pair, with some services arriving at Madrid, Estación Sur de Autobuses. Use this guide to compare Setúbal and Madrid bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Setúbal, Interface Transportes has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Food options include: Snack bars and vending machines available.
Free WiFi available in designated areas. ATMs are available at Setúbal, Interface Transportes.
Ticket office support is available at Setúbal, Interface Transportes.
Available at Setúbal, Interface Transportes: Parking, Taxis, WC.
Accessibility facilities are available at Setúbal, Interface Transportes: Wheelchair accessible entrances and facilities.
Setúbal, Terminal Rodoviário (TST) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Food options include: Small cafe inside the station offering snacks.
Wi-Fi is available at Setúbal, Terminal Rodoviário (TST). ATMs are available at Setúbal, Terminal Rodoviário (TST).
Ticket office support is available at Setúbal, Terminal Rodoviário (TST).
Available at Setúbal, Terminal Rodoviário (TST): Parking, Taxis, WC.
Accessibility facilities are available at Setúbal, Terminal Rodoviário (TST): Wheelchair accessible with ramps and elevators.
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) is 12 km from Madrid city centre. Public transport options include:
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) has practical services for this route, including Dining, ATM, Accessibility, WC, Shower and Ticket Office.
Food options include: Rodilla, Mahoudrid
ATMs are aTMs located throughout T4, major cards accepted .
Ticket office support is available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid).
Available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): WC.
Accessibility facilities are available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): Step-free access, elevators, accessible toilets.
Madrid, Estación Sur de Autobuses is 3 km from Madrid city centre. Public transport options include:
Madrid, Estación Sur de Autobuses has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food options include: Cafetería de la estación (in the station), Restaurante El Brillante (0.5 km), La Taberna de Domínguez (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.
Ticket office support is available at Madrid, Estación Sur de Autobuses.
Available at Madrid, Estación Sur de Autobuses: Parking, Taxis, WC.
Accessibility facilities are available at Madrid, Estación Sur de Autobuses: Elevators, ramps.
Here are some other resources that might have the information you need