- Must visit
Musée des Beaux-Arts de Lyon
Leading fine arts museum in a former abbey, with strong collections of painting, sculpture, antiquities and decorative arts in a grand setting.
Cheapest price
£97
Average price
£113
Fastest journey
19 h 5 m
Average duration
19 h 40 m
Buses per day
3
Distance
730 km
The best way to find a cheap coach ticket from Santander to Lyon is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Santander to Lyon will cost around £113 if you buy it on the day, but you can find cheap coach tickets today for only £97.
To travel from Santander to Lyon you need to make at least one change.
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Normal · NormalOmio recommends booking the coach as it is the most popular option from Santander to Lyon among Omio's users. If you are prioritising price take the coach with prices starting from £32. For those with little time consider booking a flight which can get you there in 2h 45m. The ticket price range depends on the travel mode: a coach costs an average of £32, and a flight costs an average of £61.
Distance: 730 km
Most popular Coach | Flight | Train |
|---|---|---|
£63 Average Price Cheapest | £195 Average Price | £139 Average Price |
15h 36m Average total duration 15h 6m Onboard + 30m Additional time* | 5h 45m Average total duration Fastest 2h 45m Onboard + 3h 0m Additional time* | 23h 52m Average total duration 23h 22m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
The table below shows live departures for Santander to Lyon coaches for today, Saturday 8 August. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
Normal · Normal | 9:00 Santander, Estación de Autobuses | 19h05 | 4:05 Lyon, Perrache Bus Station | 1 change | |
Normal · Normal | 9:00 Santander, Estación de Autobuses | 20h15 | 5:15 Lyon, Perrache Bus Station | 1 change | |
Normal · Normal | 18:00 Santander, Estación de Autobuses | 13h59 | 7:59 Lyon, Perrache Bus Station | 1 change | |
Normal · Normal | 18:00 Santander, Estación de Autobuses | 13h59 | 7:59 Lyon, Perrache Bus Station | 1 change | |
FlixBus · FlixBus | 18:55 Santander, Estación de Autobuses | 15h55 | 10:50 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change |
Find all the dates and times for this journey
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Santander to Lyon run on average 2 times per day, taking around 15h 6m. Cheap bus tickets for this journey start at £32 if you book in advance.
The earliest coach runs at 00:55, the last at 23:35. The fastest coach covers the 730 km distance in 16h 0m.
Distance 730 km |
Average bus duration 15h 6m |
Cheapest ticket price £32 |
Buses per day 2 |
Fastest bus 16h 0m |
First bus 0:55 |
Last bus 23:35 |
Cheapest Month Dec |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Thu |
Least Busy Day Fri |
Best time to book 21 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Leading fine arts museum in a former abbey, with strong collections of painting, sculpture, antiquities and decorative arts in a grand setting.
Modern museum exploring natural history, science and societies through immersive design and striking architecture at the tip of the Presqu’île.
Museum dedicated to cinema and miniature art, featuring detailed sets, props and displays linked to the Lumière brothers and visual storytelling.
Renaissance quarter of lanes, courtyards and traboules. It is one of the best areas for walking, architecture and discovering historic Lyon at street level.
Central square known for open space, fountains and major events. A practical starting point for exploring Presqu’île and the city centre on foot.
Slopes district of stairways, murals and creative energy. It blends local life, independent shops and striking urban views between Rhône and Saône.
Rich fish stew from the Lyon area, usually made with freshwater fish, crayfish and vegetables, often finished with cream. A regional speciality tied to local rivers.
Soft dumplings made with pike and choux pastry, typically baked with creamy sauce. A classic Lyonnais dish served in bouchons and family restaurants.
Warm salad of frisée lettuce with bacon lardons, croutons and a poached egg. It is a staple of traditional bouchon cooking in Lyon.
Refined dining room known for elegant French cuisine rooted in Lyon tradition. Suitable for a special meal with polished service.
Well-known traditional bouchon with hearty regional cooking and an old Lyon atmosphere. Good for charcuterie, offal dishes and local desserts.
Historic bouchon serving classic Lyonnais dishes in a warm, traditional setting. A reliable choice for quenelles, salads and local specialities.
Moderate for France: hotels and dining are cheaper than Paris, but central stays and bouchons still add up. Public transport is good value.
Service is included in restaurant bills. Rounding up or leaving 5-10% for great service is appreciated. Round up for taxis; cafés often just leave small change.
Official public transport app
Lyon Perrache Bus Station -> Place Bellecour, Lyon
Find answers to the most common questions about traveling from Santander to Lyon by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Most Santander to Lyon buses use the Santander, Estación de Autobuses to Lyon, Gare Routière de Perrache station pair, with some services arriving at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). Use this guide to compare Santander and Lyon bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Lyon, St Exupéry Aéroport is 2 km from Lyon city centre. Public transport options include:
Lyon, St Exupéry Aéroport has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Wi-Fi is available at Lyon, St Exupéry Aéroport. ATMs are available at Lyon, St Exupéry Aéroport.
Ticket office support is available at Lyon, St Exupéry Aéroport.
Available at Lyon, St Exupéry Aéroport: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, St Exupéry Aéroport: Access ramps and services available.
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