- Must visit
Musée des Beaux-Arts de Lyon
Leading fine arts museum in a former abbey, with strong collections of painting, sculpture, antiquities and decorative arts in a grand setting.
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The cheapest and fastest coaches from Santander to Lyon
Showing times, prices and bookable tickets for 23 Sept
Cheapest price on 23 Sept
£40
Average ticket price on 23 Sept
£53
Fastest journey on 23 Sept
19 h 5 m
Average journey duration on 23 Sept
20 h 53 m
Buses on 23 Sept
2
Distance
730 km
Cheap tickets
The best way to find a cheap coach ticket from Santander to Lyon is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Santander to Lyon will cost around £53 if you buy it on the day, but you can find cheap coach tickets today for only £40.
Fast coaches
To travel from Santander to Lyon you need to make at least one change.
Normal · Normal9:0019h05Santander, Estación de Autobuses4:05Lyon, Perrache Bus Station£401One-way1 change
FlixBus · FlixBus · FlixBus18:5022h40Santander, Estación de Autobuses17:30Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)£671One-way2 changes
- Normal · Normal9:0019h05Santander, Estación de Autobuses4:05Lyon, Perrache Bus Station£401One-way1 change
- FlixBus · FlixBus · FlixBus18:5022h40Santander, Estación de Autobuses17:30Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)£671One-way2 changes
Travel Information
Compare train, coach and flight for Santander to Lyon
Omio recommends booking the coach as it is the most popular option from Santander to Lyon among Omio's users. If you are prioritising price, take the coach, with an average ticket price of £56 For those with little time, consider booking a flight, which has an average total journey time of 4h 54m. Average ticket prices depend on the travel mode: a coach costs an average of £56, while a flight costs an average of £422.
Distance: 730 km
Compare bus with
Most popular Coach | Flight | Driving |
|---|---|---|
£56 Average Price Cheapest | £422 Average Price | £144 Average Price (fuel + tolls) |
16h 31m Average total duration 16h 1m Onboard + 30m Additional time* | 4h 54m Average total duration Fastest 2h 54m Onboard + 2h 0m Additional time* | 9h 42m Average total duration (door-to-door) |
 Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Santander to Lyon is a coach with an average price of £56.
This is compared to other travel options from Santander to Lyon:
A coach is £365 less than a flight for this route with tickets for a flight from Santander to Lyon costing on average £422.
The fastest way to travel from Santander to Lyon is by flight with an average journey time of 2h 54m.
Other travel options to Lyon take longer:
Coach takes on average 16h 1m.
It's helpful to compare your options as there are 3 ways to travel between Santander and Lyon including taking a train, coach and flight.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around £56 compared to roughly £144 in fuel and tolls — a saving of about £88. The journey takes 16h 1m versus 9h 42m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by KLR.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Live departures
Santander to Lyon bus times
The table below shows live departures for Santander to Lyon coaches for today, Tuesday 22 September. You can also manually refresh the results below to see updated coach journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
| Normal · Normal | 9:00 Santander, Estación de Autobuses | 19h05 | 4:05 Lyon, Perrache Bus Station | 1 change | |
| FlixBus · FlixBus | 18:50 Santander, Estación de Autobuses | 16h00 | 10:50 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santander to Lyon by train, coach or flight
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Santander to Lyon coaches with Omio?
KLR as well as Alsa, BlaBlaCar Bus, Internorte, FlixBus and more offer coaches services from Santander to Lyon.
Omio is an official ticket reseller for all your travel options from Santander to Lyon.
Why book with Omio vs KLR?
- Compare with other providers: On Omio, you can not only buy tickets for KLR, but also compare tickets for the likes of Alsa, BlaBlaCar Bus, Internorte or FlixBus to find the best option for your trip from Santander to Lyon.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare KLR with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Santander to Lyon.
Why book with Omio over Checkmybus, Rome2rio or Busbud?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Alsa, BlaBlaCar Bus, Internorte or FlixBus to find the best option for your trip from Santander to Lyon.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Santander to Lyon.
Journey information
Overview: Bus from Santander to Lyon
Spain
France
Buses from Santander to Lyon run on average 4 times per day, taking around 16h 1m. Cheap bus tickets for this journey start at £7 if you book in advance.
The earliest coach runs at 00:55, the last at 23:35. The fastest coach covers the 730 km distance in 13h 9m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 730 km |
Average bus duration 16h 1m |
Cheapest ticket price £7 |
Buses per day 4 |
Fastest bus 13h 9m |
First bus 0:55 |
Last bus 23:35 |
Cheapest Month Dec |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Fri |
Least Busy Day Fri |
Best time to book 14 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Alsa, BlaBlaCar Bus, FlixBus, Internorte, KLR from Santander to LyonYou can travel by bus between Santander to Lyon with Alsa, BlaBlaCar Bus, FlixBus, Internorte, KLR for as low as £7. When you search for schedules and tickets, Omio will show you the best journey
Alsa
About
Alsa is the main provider of bus travel in Spain and a subsidiary of the UK’s National Express. It operates an extensive network of regional, national, and international routes, transporting more than 300 million passengers annually. Alsa’s modern fleet offers varying levels of comfort and amenities. The standard Alsa Normal buses include free Wi-Fi, onboard bathrooms, footrests, and entertainment. For a more premium experience, Alsa Supra, Alsa Eurobus, and Alsa Premium services provide enhanced comfort and luxury features.
Luggage & cancellation policy
Average Alsa Duration
13h 9m
Cheapest Alsa Price
£25
Alsa frequency
2 a day
Luggage included
One carry-on bag up to 10kg and one checked bag up to 25kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 48 hours before departure for a partial refund. Changes allowed for a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating.
Bikes
Bikes are allowed for an additional fee; must be packed.
Pets
Small pets allowed in carriers; larger pets must travel in the hold.
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
14h 5m
Cheapest FlixBus Price
£46
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
BlaBlaCar Bus
About
BlaBlaCar Bus (formerly known as Ouibus or iDBUS) is a long-distance coach company operating in 10 European countries and connecting over 300 destinations. A subsidiary of the French carpooling company BlaBlaCar, it offers comfortable travel with standard amenities such as air conditioning, toilets, USB and power outlets for charging devices, extra legroom, and adjustable seats. Free Wi-Fi is available on select routes. BlaBlaCar Bus offers only a Standard ticket type, which allows passengers to bring one carry-on bag and up to two checked bags per person.
Luggage & cancellation policy
Average BlaBlaCar Bus Duration
13h 16m
Cheapest BlaBlaCar Bus Price
£7
BlaBlaCar Bus frequency
1 a day
Luggage included
One carry-on bag up to 7kg and one checked bag up to 20kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating options.
Bikes
Bikes are allowed; additional fees may apply.
KLR
About
KLR Bus is a Ukrainian carrier offering comfortable and safe international bus transportation since 2012. Serving over 100 cities across more than 15 European countries, including Germany, Poland, and Spain, KLR Bus operates a modern fleet equipped with amenities such as air conditioning, Wi-Fi, and onboard restrooms. Passengers can conveniently book tickets online and enjoy features like real-time bus tracking and electronic tickets accessible via the KLR-Bus mobile app. The company is committed to providing affordable travel options, with special offers and discounts available to app users.
Luggage & cancellation policy
Average KLR Duration
14h 35m
Cheapest KLR Price
£33
KLR frequency
1 a day
Luggage included
Each passenger is allowed one checked bag with a maximum weight of 20 kg and one personal bag free of charge.
Additional luggage
Additional luggage is subject to extra fees based on weight and size.
Luggage storage
Luggage is stored in the bus's luggage compartment.
Cancellation Policy
No refunds are allowed; changes can be made with a fee if done at least 96 hours before departure.
Refund
No refunds are allowed under any circumstances.
Unaccompagned minor
Children under 12 must travel with an adult; those under 16 require parental consent.
Amenities on board the bus
Toilets
Internorte
Luggage & cancellation policy
Average Internorte Duration
13h 59m
Cheapest Internorte Price
£71
Internorte frequency
1 a day
Complete guide to Lyon
Things to do in Lyon
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
- Must visit
Musée des Confluences
Modern museum exploring natural history, science and societies through immersive design and striking architecture at the tip of the Presqu’île.
- Recommended
Musée Cinéma et Miniature
Museum dedicated to cinema and miniature art, featuring detailed sets, props and displays linked to the Lumière brothers and visual storytelling.
- Must visit
Vieux Lyon
Renaissance quarter of lanes, courtyards and traboules. It is one of the best areas for walking, architecture and discovering historic Lyon at street level.
- Must visit
Place Bellecour
Central square known for open space, fountains and major events. A practical starting point for exploring Presqu’île and the city centre on foot.
- Recommended
La Croix-Rousse
Slopes district of stairways, murals and creative energy. It blends local life, independent shops and striking urban views between Rhône and Saône.
Quenelles de Brochet Sauce Nantua
Rich fish stew from the Lyon area, usually made with freshwater fish, crayfish and vegetables, often finished with cream. A regional speciality tied to local rivers.
Quenelles de Brochet
Soft dumplings made with pike and choux pastry, typically baked with creamy sauce. A classic Lyonnais dish served in bouchons and family restaurants.
Salade Lyonnaise
Warm salad of frisée lettuce with bacon lardons, croutons and a poached egg. It is a staple of traditional bouchon cooking in Lyon.
Restaurant Paul Bocuse
Refined dining room known for elegant French cuisine rooted in Lyon tradition. Suitable for a special meal with polished service.
Daniel et Denise
Well-known traditional bouchon with hearty regional cooking and an old Lyon atmosphere. Good for charcuterie, offal dishes and local desserts.
Le Musée
Historic bouchon serving classic Lyonnais dishes in a warm, traditional setting. A reliable choice for quenelles, salads and local specialities.
Euro (€)
Moderate for France: hotels and dining are cheaper than Paris, but central stays and bouchons still add up. Public transport is good value.
Average meal costs
- Budget
- €10-15 for fast food or a simple lunch.
- Mid-range
- €20-35 per person for a restaurant meal.
- Fine dining
- €70+ per person for upscale dining.
- Coffee
- €2.50-4 for a coffee.
Tipping culture
Service is included in restaurant bills. Rounding up or leaving 5-10% for great service is appreciated. Round up for taxis; cafés often just leave small change.
TCL
Get the appOfficial public transport app
Prices
- Single ticket
- €2.10
- Day pass
- €6.90
To the city centre
Lyon Perrache Bus Station -> Place Bellecour, Lyon
- Distance
- 1.5 km
- Travel time
- 10 min
- Use the TCL app for live journeys and ticket information. TCL lists route planning and real-time network information in the official app.
- A rechargeable ticket is used on the TCL network. Check station machines or the official app for current payment and validation options before travel.
FAQs: Santander to Lyon coach
Find answers to the most common questions about traveling from Santander to Lyon by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.
Cheap coach tickets from Santander to Lyon can start from as little as £7 when you book in advance. The average coach ticket price for Santander to Lyon is £56; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by coach from Santander to Lyon is 13h 9m to travel the 730 km long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest coach from Santander to Lyon leaves at 0:55. Plan your trip with the Journey Planner from Omio.
The latest coach from Santander to Lyon leaves at 23:35.
There are 4 coaches a day from Santander to Lyon which require at least one change with KLR, Alsa, BlaBlaCar Bus, Internorte, FlixBus. Schedules can vary on holidays or weekends with fewer coaches.
When taking a coach from Santander to Lyon, you can count on KLR, Alsa, BlaBlaCar Bus, Internorte, FlixBus for the best way to get you to Lyon. You can also check all possible coach companies who offer a service between Santander and Lyon and compare the amenities they offer before buying a coach ticket.
When departing from Santander , you have various coach station options to start your route from including Santander, Estación de Autobuses . When arriving in Lyon , you can end your route in coach stations like Lyon, Perrache Bus Station, Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland), Lyon, St Exupéry Aéroport, Givors, Plaza Jean Berry.Passengers board the coach most frequently from Santander, Estación de Autobuses, which is located around away from the city centre, and they get off the coach at Lyon, Perrache Bus Station, located 1 away from the city centre.
A trip to Lyon from Santander is worth doing but not as a day trip with a journey time of 13h 9m each way. Check with Omio app the best way to travel.
The cheapest month for a coach from Santander to Lyon is December.
It's helpful to compare your options as there are 3 ways to travel between Santander and Lyon including taking a train, coach and flight.
Yes, the following accessibility options are available when taking the coach from Santander to Lyon:
- Alsa
- Assistance
- Priority boarding
- Accessible seating.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the coach from Santander to Lyon for coach company KLR, Alsa, BlaBlaCar Bus, FlixBus.
Whether you can cancel your coach ticket from Santander to Lyon depends on the coach companies:
- KLR
- No refunds are allowed
- changes can be made with a fee if done at least 96 hours before departure.
- Alsa
- You can cancel your ticket up to 48 hours before departure for a partial refund. Changes allowed for a fee.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
Yes, bikes are allowed on board the coach with coach company Alsa, BlaBlaCar Bus, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the coach from Santander to Lyon.
Yes, the following luggage options are included when booking a coach ticket from Santander to Lyon:
- KLR
- Each passenger is allowed one checked bag with a maximum weight of 20 kg and one personal bag free of charge.
- Alsa
- One carry-on bag up to 10kg and one checked bag up to 25kg.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
Yes, the following additional luggage options are available when booking a coach ticket from Santander to Lyon:
- KLR
- Additional luggage is subject to extra fees based on weight and size.
- Alsa
- Additional luggage can be purchased for a fee.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the coach from Santander to Lyon. The following conditions apply:
- Alsa
- Small pets allowed in carriers
- larger pets must travel in the hold.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the coach from Santander to Lyon with the following coach company: Alsa, BlaBlaCar Bus, FlixBus
Yes, there are USB plugs on board the coach from Santander to Lyon with the following coach company: Alsa, BlaBlaCar Bus, FlixBus.
Yes, there is Wifi on board the coach from Santander to Lyon with the following coach company: Alsa, BlaBlaCar Bus, FlixBus.
popular bus stations
Important Stations and Airports in Santander and Lyon
Most Santander to Lyon buses use the Santander, Estación de Autobuses to Lyon, Gare Routière de Perrache station pair, with some services arriving at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). Use this guide to compare Santander and Lyon bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Santander
Arrival bus stations in Lyon
Santander, Estación de AutobusesSantander Bus Station, Calle Navas de Tolosa 2, 39002
Which Lyon station do buses from Santander arrive at?
Buses from Santander to Lyon most often arrive at Lyon, Gare Routière de Perrache. Some services arrive at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland), so check your ticket before travel to confirm your Lyon arrival station.
Lyon, Gare Routière de Perrache13 Cours de Verdun, 69002 Lyon, France
City-centre transport
Getting to Lyon, Gare Routière de Perrache from Lyon city centre
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
TrainTer · 5m · £0.90 · every ~5 min
Lyon, Gare Routière de Perrache bus station facilities and services
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food and drink
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance.
Tickets and information
Ticket office support is available at Lyon, Gare Routière de Perrache.
Parking, taxis and toilets
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)52 Av. Tony Garnier, 69007 Lyon, France
City-centre transport
Getting to Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) from Lyon city centre
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
BusN734 · 15m · £0.90
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) bus station facilities and services
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Tickets and information
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Parking, taxis and toilets
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Lyon, St Exupéry AéroportLyon St Exupéry Aéroport, 69125 Colombier-Saugnieu, France
City-centre transport
Getting to Lyon, St Exupéry Aéroport from Lyon city centre
Lyon, St Exupéry Aéroport is 2 km from Lyon city centre. Public transport options include:
TrainRx · 29m · £14 · every ~8 min
BusS766, 776, 787, N760, N1759, 1776, 1624, N746, 1779, S1736, 1606, 1787, 1676 · 38m · £2 · every ~1 min
Lyon, St Exupéry Aéroport bus station facilities and services
Lyon, St Exupéry Aéroport has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Lyon, St Exupéry Aéroport. ATMs are available at Lyon, St Exupéry Aéroport.
Tickets and information
Ticket office support is available at Lyon, St Exupéry Aéroport.
Parking, taxis and toilets
Available at Lyon, St Exupéry Aéroport: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lyon, St Exupéry Aéroport: Access ramps and services available.
Most popular bus connections from Santander
More options for your journey from Santander to Lyon
Here are some other resources that might have the information you need
Most popular buses to and from Lyon and Santander
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