- Must visit
Musée des Beaux-Arts de Lyon
Leading fine arts museum in a former abbey, with strong collections of painting, sculpture, antiquities and decorative arts in a grand setting.
Cheapest price
£22
Average price
£38
Fastest journey
10 h 20 m
Average duration
10 h 28 m
Buses per day
23
Distance
569 km
The best way to find a cheap coach ticket from Brussels to Lyon is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Brussels to Lyon will cost around £38 if you buy it on the day, but you can find cheap coach tickets today for only £22.
Of the 23 buses that leave Brussels for Lyon every day 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct buses cover the 569 km distance in an average of 10 h 28 m but if you time it right, some buses will get you there in just 10 h 20 m .
The slowest buses will take 10 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
51112 · 5133
50338 · 50883
50338 · 4787
1408 · 5807
1680 · 50755
50338 · 50883
50338 · 4787
50332 · 3357
FlixBus
1408 · 5807Omio recommends booking the train as it is the most popular option from Brussels to Lyon among Omio's users. If you are prioritising price take the coach with prices starting from £21. For those with little time consider booking a flight which can get you there in 2h 24m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a coach costs an average of £21, and a flight costs an average of £94.
Distance: 569 km
| Coach | Most popular Train | Flight |
|---|---|---|
£40 Average Price Cheapest | £111 Average Price | £220 Average Price |
8h 33m Average total duration 8h 3m Onboard + 30m Additional time* | 4h 59m Average total duration 4h 29m Onboard + 30m Additional time* | 5h 24m Average total duration Fastest 2h 24m Onboard + 3h 0m Additional time* |
0.6 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.4kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The table below shows live departures for Brussels to Lyon coaches for today, Sunday 23 August. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 16:40 Brussels, Brussels South (Gare du Midi) | 12h10 | 4:50 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change | |
50336 · 50617 | 16:55 Brussels, Brussels South (Gare du Midi) | 10h35 | 3:30 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change | |
FlixBus · FlixBus | 17:40 Brussels, Brussels South (Gare du Midi) | 10h55 | 4:35 Lyon | 1 change | |
1408 · 5807 | 17:55 Brussels, Brussels South (Gare du Midi) | 10h35 | 4:30 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change | |
51112 · 5133 | 18:20 Brussels, Brussels South (Gare du Midi) | 11h00 | 5:20 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change | |
50338 · 4787 | 19:05 Brussels, Brussels South (Gare du Midi) | 10h20 | 5:25 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change | |
50338 · 50883 | 19:05 Brussels, Brussels South (Gare du Midi) | 10h20 | 5:25 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change | |
FlixBus | 20:15 Brussels, Brussels South (Gare du Midi) | 10h35 | 6:50 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 changesdirect | |
51094 | 22:15 Brussels, Brussels South (Gare du Midi) | 11h00 | 9:15 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 changesdirect | |
| Monday 24 August | |||||
1698 · 58073 | 2:15 Brussels, Brussels South (Gare du Midi) | 11h25 | 13:40 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change | |
50449 · 94765 | 2:35 Brussels, Brussels South (Gare du Midi) | 12h05 | 14:40 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change | |
1608 · 54031 | 3:11 Brussels, Brussels South (Gare du Midi) | 10h49 | 14:00 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change | |
FlixBus · FlixBus | 4:15 Brussels, Brussels South (Gare du Midi) | 12h10 | 16:25 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change | |
50320 · 5131 | 7:20 Brussels, Brussels South (Gare du Midi) | 11h30 | 18:50 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change | |
1430 · 50471 | 8:05 Brussels, Brussels South (Gare du Midi) | 11h05 | 19:10 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change | |
FlixBus · FlixBus | 10:05 Brussels, Gare Du Midi | 13h45 | 23:50 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change | |
FlixBus · FlixBus | 11:05 Brussels, Brussels South (Gare du Midi) | 12h45 | 23:50 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change | |
50310 · 94763 | 12:05 Brussels, Brussels South (Gare du Midi) | 11h45 | 23:50 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change | |
1646 · 50107 | 13:30 Brussels, Brussels South (Gare du Midi) | 10h50 | 0:20 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change | |
FlixBus · FlixBus | 13:40 Brussels, Brussels South (Gare du Midi) | 13h30 | 3:10 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change | |
50332 · 3357 | 14:20 Brussels, Brussels South (Gare du Midi) | 10h30 | 0:50 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change | |
1680 · 50755 | 15:30 Brussels, Brussels South (Gare du Midi) | 10h50 | 2:20 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change | |
50429 · 83133 | 15:50 Brussels, Brussels South (Gare du Midi) | 12h15 | 4:05 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 change | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Brussels to Lyon run on average 15 times per day, taking around 8h 3m. Cheap bus tickets for this journey start at £21 if you book in advance.
There are 3 coaches per day. The earliest coach runs at 00:10, the last at 23:55. The fastest coach covers the 569 km distance in 10h 10m.
Distance 569 km |
Average bus duration 8h 3m |
Cheapest ticket price £21 |
Buses per day 15 |
Direct buses 3 |
Fastest bus 10h 10m |
First bus 0:10 |
Last bus 23:55 |
Cheapest Month Sept |
Cheapest Day Sat |
High Season Jul - Sept |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sun |
Best time to book 84 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Leading fine arts museum in a former abbey, with strong collections of painting, sculpture, antiquities and decorative arts in a grand setting.
Modern museum exploring natural history, science and societies through immersive design and striking architecture at the tip of the Presqu’île.
Museum dedicated to cinema and miniature art, featuring detailed sets, props and displays linked to the Lumière brothers and visual storytelling.
Renaissance quarter of lanes, courtyards and traboules. It is one of the best areas for walking, architecture and discovering historic Lyon at street level.
Central square known for open space, fountains and major events. A practical starting point for exploring Presqu’île and the city centre on foot.
Slopes district of stairways, murals and creative energy. It blends local life, independent shops and striking urban views between Rhône and Saône.
Rich fish stew from the Lyon area, usually made with freshwater fish, crayfish and vegetables, often finished with cream. A regional speciality tied to local rivers.
Soft dumplings made with pike and choux pastry, typically baked with creamy sauce. A classic Lyonnais dish served in bouchons and family restaurants.
Warm salad of frisée lettuce with bacon lardons, croutons and a poached egg. It is a staple of traditional bouchon cooking in Lyon.
Refined dining room known for elegant French cuisine rooted in Lyon tradition. Suitable for a special meal with polished service.
Well-known traditional bouchon with hearty regional cooking and an old Lyon atmosphere. Good for charcuterie, offal dishes and local desserts.
Historic bouchon serving classic Lyonnais dishes in a warm, traditional setting. A reliable choice for quenelles, salads and local specialities.
Moderate for France: hotels and dining are cheaper than Paris, but central stays and bouchons still add up. Public transport is good value.
Service is included in restaurant bills. Rounding up or leaving 5-10% for great service is appreciated. Round up for taxis; cafés often just leave small change.
Official public transport app
Lyon Perrache Bus Station -> Place Bellecour, Lyon
Find answers to the most common questions about traveling from Brussels to Lyon by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Most Brussels to Lyon buses use the Brussels, Brussels South (Gare du Midi) to Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) station pair, with some services arriving at Lyon, Gare Routière de Perrache. Use this guide to compare Brussels and Lyon bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Brussels, Gare Du Midi is 1 km from Brussels city centre. Public transport options include:
Brussels, Gare Du Midi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Food options include: Various dining options are nearby.
Wi-Fi is available at Brussels, Gare Du Midi. ATMs are available at Brussels, Gare Du Midi.
Ticket office support is available at Brussels, Gare Du Midi.
Available at Brussels, Gare Du Midi: Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Gare Du Midi: Station is accessible for individuals with disabilities.
Brussels-Noord is 1 km from Brussels city centre. Public transport options include:
Brussels-Noord has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food options include: Cafeteria Noord (in the station), Quick Brussels Noord (in the station), Le Pain Quotidien (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.
Ticket office support is available at Brussels-Noord.
Available at Brussels-Noord: Parking, Taxis, WC.
Accessibility facilities are available at Brussels-Noord: Elevators, ramps.
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Lyon, St Exupéry Aéroport is 2 km from Lyon city centre. Public transport options include:
Lyon, St Exupéry Aéroport has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Wi-Fi is available at Lyon, St Exupéry Aéroport. ATMs are available at Lyon, St Exupéry Aéroport.
Ticket office support is available at Lyon, St Exupéry Aéroport.
Available at Lyon, St Exupéry Aéroport: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, St Exupéry Aéroport: Access ramps and services available.
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