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FlixBus · FlixBus · FlixBus13:0528h50Roma, Autostazione (Metro Anagnina)17:55Brussels, Brussels South (Gare du Midi)£1081One-way2 changes- FlixBus · FlixBus · FlixBus17:2531h10Roma, Autostazione (Metro Anagnina)0:35Brussels, Brussels South (Gare du Midi)£1201One-way2 changes
- FlixBus · FlixBus · FlixBus22:4528h20Roma, Autostazione Tiburtina3:05Brussels, Brussels South (Gare du Midi)£1251One-way2 changes
4788 · 143315:2026h10Roma, Autostazione Tiburtina17:30Brussels, Brussels South (Gare du Midi)£1371One-way1 change- FlixBus · FlixBus · FlixBus12:1029h45Roma, Autostazione Tiburtina17:55Brussels, Brussels South (Gare du Midi)£1391One-way2 changes
- 4788 · 143315:2026h10Roma, Autostazione Tiburtina17:30Brussels, Brussels South (Gare du Midi)£1371One-way1 change
- FlixBus · FlixBus · FlixBus9:2527h20Roma, Autostazione Tiburtina12:45Brussels, Brussels South (Gare du Midi)£1411One-way2 changes
- FlixBus · FlixBus · FlixBus22:4528h20Roma, Autostazione Tiburtina3:05Brussels, Brussels South (Gare du Midi)£1251One-way2 changes
- FlixBus · FlixBus · FlixBus7:4528h35Roma, Autostazione Tiburtina12:20Brussels, Brussels South (Gare du Midi)£1411One-way2 changes
- FlixBus · FlixBus · FlixBus13:0528h50Roma, Autostazione (Metro Anagnina)17:55Brussels, Brussels South (Gare du Midi)£1081One-way2 changes
Travel Information
Compare coach and flight for Rome to Brussels
The cheapest option from Rome to Brussels is flight, with an average price of £99. Omio recommends booking the flight, as it is the most popular option from Rome to Brussels among Omio users. If you are seeking to minimise your carbon footprint, the bus is your best option, as it emits only 1.2 - 2.9kg.
Distance: 1174 km
Compare bus with
| Coach | Most popular Flight |
|---|---|
£99 Average Price Cheapest option | £121 Average Price |
27h 8m Average total duration 26h 38m Onboard + 30m Additional time* | 6h 7m Average total duration Fastest option 3h 7m Onboard + 3h 0m Additional time* |
1.2 - 2.9kg CO2 emissions Lowest | 3.5 - 7.0kg CO2 emissions |
Most popular bus company |  Most popular airline |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Rome to Brussels bus times
The table below shows live departures for Rome to Brussels coaches for today, Sunday 5 July. You can also manually refresh the results below to see updated coach journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus · FlixBus | 9:30 Roma, Autostazione Tiburtina | 28h25 | 13:55 Brussels, Brussels South (Gare du Midi) | 2 changes | |
| 4788 · 50327 | 15:20 Roma, Autostazione Tiburtina | 25h10 | 16:30 Brussels, Brussels South (Gare du Midi) | 1 change | |
| FlixBus · FlixBus · FlixBus | 21:00 Roma, Autostazione Tiburtina | 30h35 | 3:35 Brussels, Brussels South (Gare du Midi) | 2 changes | |
| Monday 6 July | |||||
| FlixBus · FlixBus · FlixBus | 7:45 Roma, Autostazione Tiburtina | 28h35 | 12:20 Brussels, Brussels South (Gare du Midi) | 2 changes | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Brussels by coach or flight
Compare coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Rome to Brussels coaches with Omio?
FlixBus as well as BlaBlaCar Bus or Autoservizi Salemi Srl offer coaches services from Rome to Brussels.
Omio is an official ticket reseller for all your travel options from Rome to Brussels.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus or Autoservizi Salemi Srl to find the best option for your trip from Rome to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Rome to Brussels.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus or Autoservizi Salemi Srl to find the best option for your trip from Rome to Brussels.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Rome to Brussels.
Journey information
Overview: Bus from Rome to Brussels
Italy
Belgium
Typically, there are 10 buses per day from Rome to Brussels, including direct buses, taking around 26h 38m. Cheap bus tickets for this journey start at £63 but you can travel from only £24 by flight.
The earliest coach runs at 00:10, the last at 23:55. The fastest coach covers the 1174 km distance in 25h 10m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from £24
Distance 1174 km |
Average bus duration 26h 38m |
Lowest ticket price £63 |
Buses per day 10 |
Fastest bus 25h 10m |
First bus 0:10 |
Last bus 23:55 |
Cheapest Month Jul |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Thu |
Best time to book 49 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from £24
Bus providers: FlixBus, BlaBlaCar Bus, Autoservizi Salemi Srl from Rome to BrusselsYou can travel by bus between Rome to Brussels with FlixBus, BlaBlaCar Bus, Autoservizi Salemi Srl for as low as £24. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
28h 20m
Cheapest Price
£63
FlixBus frequency
3 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
BlaBlaCar Bus
About
BlaBlaCar Bus (formerly known as Ouibus or iDBUS) is a long-distance coach company operating in 10 European countries and connecting over 300 destinations. A subsidiary of the French carpooling company BlaBlaCar, it offers comfortable travel with standard amenities such as air conditioning, toilets, USB and power outlets for charging devices, extra legroom, and adjustable seats. Free Wi-Fi is available on select routes. BlaBlaCar Bus offers only a Standard ticket type, which allows passengers to bring one carry-on bag and up to two checked bags per person.
Luggage & cancellation policy
Average Duration
25h 10m
Cheapest Price
£72
Luggage included
One carry-on bag up to 7kg and one checked bag up to 20kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating options.
Bikes
Bikes are allowed; additional fees may apply.
Autoservizi Salemi Srl
Luggage & cancellation policy
Average Duration
22h 35m
Cheapest Price
£96
Autoservizi Salemi Srl frequency
1 a day
FAQs: Rome to Brussels coach
Find answers to the most common questions about traveling from Rome to Brussels by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.
The earliest coach from Rome to Brussels leaves at 0:10. Plan your trip with the Journey Planner from Omio.
The latest coach from Rome to Brussels leaves at 23:55.
There are 10 coaches a day from Rome to Brussels which require at least one change with FlixBus, BlaBlaCar Bus, Autoservizi Salemi Srl. Schedules can vary on holidays or weekends with fewer coaches.
When taking a coach from Rome to Brussels, you can count on FlixBus, BlaBlaCar Bus, Autoservizi Salemi Srl for the best way to get you to Brussels. You can also check all possible coach companies who offer a service between Rome and Brussels and compare the amenities they offer before buying a coach ticket.
The cheapest month for a coach from Rome to Brussels is July.
It's helpful to compare your options as there are 2 ways to travel between Rome and Brussels including taking a coach and flight.
Yes, the following accessibility options are available when taking the coach from Rome to Brussels:
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the coach from Rome to Brussels for coach company FlixBus, BlaBlaCar Bus.
Whether you can cancel your coach ticket from Rome to Brussels depends on the coach companies:
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the coach with coach company FlixBus, BlaBlaCar Bus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the coach from Rome to Brussels.
Yes, the following luggage options are included when booking a coach ticket from Rome to Brussels:
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a coach ticket from Rome to Brussels:
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the coach from Rome to Brussels. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the coach from Rome to Brussels with the following coach company: FlixBus, BlaBlaCar Bus
Yes, there are USB plugs on board the coach from Rome to Brussels with the following coach company: FlixBus, BlaBlaCar Bus.
Yes, there is Wifi on board the coach from Rome to Brussels with the following coach company: FlixBus, BlaBlaCar Bus.
popular bus stations
Important Stations and Airports in Rome and Brussels
Most Rome to Brussels buses use the Roma, Autostazione Tiburtina to Brussels, Brussels South (Gare du Midi) station pair, with some services arriving at Brussels, Gare Du Midi. Use this guide to compare Rome and Brussels bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Rome
Arrival bus stations in Brussels
Roma, Autostazione Tiburtina
City-centre transport
Getting to Roma, Autostazione Tiburtina from Rome city centre
Bus490, 495 · 16m · £2 · every ~22 min
SubwayMeb · 7m · £2 · every ~15 min
Roma, Autostazione (Metro Anagnina)Rome Anagnina, Via Tuscolana, 173
City-centre transport
Getting to Roma, Autostazione (Metro Anagnina) from Rome city centre
BusRome Fiumicino, Scario · 31m · £0.90
nMA · 38m · £2 · every ~4 min
SubwayMea · 24m · £2 · every ~29 min
Shuttle31m · £9
Which Brussels station do buses from Rome arrive at?
Buses from Rome to Brussels most often arrive at Brussels, Brussels South (Gare du Midi). Some services arrive at Brussels, Gare Du Midi, so check your ticket before travel to confirm your Brussels arrival station.
Brussels, Brussels South (Gare du Midi)Avenue Fonsny 47, 1060 Brussels, Belgium
City-centre transport
Getting to Brussels, Brussels South (Gare du Midi) from Brussels city centre
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
TrainEuroCity · 4m · £0.90 · every ~2 min
Ice · 14m · £0.90
Bus48 · 16m · £3 · every ~9 min
Bus · 20m
FlixBus N1153 · 29m · £0.90
Subway2, 6 · 18m · £3 · every ~38 min
Brussels, Brussels South (Gare du Midi) bus station facilities and services
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food and drink
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Tickets and information
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Parking, taxis and toilets
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Brussels, Gare Du Midi
City-centre transport
Getting to Brussels, Gare Du Midi from Brussels city centre
TrainEuroCity · 4m · £0.90 · every ~2 min
Ice · 14m · £0.90
Bus48 · 16m · £3 · every ~9 min
Bus · 20m
FlixBus N1153 · 29m · £0.90
Subway2, 6 · 18m · £3 · every ~38 min
Brussel, Avenue des Magnolias (Koning Boudewijn)
City-centre transport
Getting to Brussel, Avenue des Magnolias (Koning Boudewijn) from Brussels city centre
Bus811 · 22m · £0.90
N18 · 24m · £3
R40, R50, R41, R60 · 33m · £3 · every ~18 min
Tram93 · 40m · £3 · every ~14 min
Subway6 · 13m · £3 · every ~20 min
6 · 22m · £4 · every ~18 min
6 · 31m · £3 · every ~18 min
Most popular bus connections from Rome
More options for your journey from Rome to Brussels
Here are some other resources that might have the information you need
Most popular buses to and from Brussels and Rome
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