The cheapest and fastest coaches from Mainz to Prague
Cheapest price
£32
Average price
£44
Fastest journey
6 h 48 m
Average duration
8 h 54 m
Buses per day
6
Distance
439 km
The best way to find a cheap coach ticket from Mainz to Prague is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Mainz to Prague will cost around £44 if you buy it on the day, but you can find cheap coach tickets today for only £32.
Of the 6 buses that leave Mainz for Prague every day 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct buses cover the 439 km distance in an average of 8 h 54 m but if you time it right, some buses will get you there in just 6 h 48 m .
The slowest buses will take 10 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
(Amsterdam -> Prague)
FlixBus
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
(Amsterdam -> Prague)
FlixBus
FlixBus
FlixBus · FlixBus
FlixBus · FlixBusTravel Information
Compare coach, train and flight for Mainz to Prague
Omio recommends booking the train as it is the most popular option from Mainz to Prague among Omio's users. If you are prioritising price take the coach with prices starting from £23. For those with little time consider booking a flight which can get you there in 1h 35m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a coach costs an average of £23, and a flight costs an average of £46.
Distance: 439 km
Compare bus with
| Coach | Most popular Train | Flight |
|---|---|---|
£34 Average Price Cheapest | £77 Average Price | £110 Average Price |
7h 36m Average total duration 7h 6m Onboard + 30m Additional time* | 8h 3m Average total duration 7h 33m Onboard + 30m Additional time* | 4h 35m Average total duration Fastest 1h 35m Onboard + 3h 0m Additional time* |
0.4 - 1.1kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.3 - 2.6kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Mainz to Prague bus times
The table below shows live departures for Mainz to Prague coaches for today, Friday 14 November. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
FlixBus | 15:00 Mainz, Binger Schlag (Kurzzeitparkplatz) | 8h05 | 23:05 Praha, Na Knížecí | 0 changesdirect | |
FlixBus | 15:00 Mainz, Binger Schlag (Kurzzeitparkplatz) | 8h25 | 23:25 Prague, Central Train Station | 0 changesdirect | |
(Amsterdam -> Prague) | 21:00 Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 6h48 | 03:48 Praha, ÚAN Florenc | 0 changesdirect | |
FlixBus · FlixBus | 22:30 Mainz, Binger Schlag (Kurzzeitparkplatz) | 11h10 | 09:40 Praha, ÚAN Florenc | 1 change | |
| Saturday 15 November | |||||
FlixBus · FlixBus | 04:15 Mainz, Binger Schlag (Kurzzeitparkplatz) | 10h45 | 15:00 Prague, Central Train Station | 1 change | |
FlixBus · FlixBus | 04:15 Mainz, Binger Schlag (Kurzzeitparkplatz) | 10h25 | 14:40 Praha, ÚAN Florenc | 1 change | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mainz to Prague by coach, train or flight
Compare coach, train and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Mainz to Prague
Buses from Mainz to Prague run on average 5 times per day, taking around 7h 6m. Cheap bus tickets for this journey start at £23 if you book in advance.
There are 3 coaches per day. The earliest coach runs at 02:05, the last at 23:40. The fastest coach covers the 439 km distance in 6h 48m.
Distance 439 km |
Average bus duration 7h 6m |
Cheapest ticket price £23 |
Buses per day 5 |
Direct buses 3 |
Fastest bus 6h 48m |
First bus 02:05 |
Last bus 23:40 |
Bus providers: FlixBus, BlaBlaCar from Mainz to PragueYou can travel by bus between Mainz to Prague with FlixBus, BlaBlaCar for as low as £23. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar
FAQs: Mainz to Prague coach
Find answers to the most common questions about traveling from Mainz to Prague by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Passengers board the coach most frequently from Mainz, Binger Schlag (Kurzzeitparkplatz), which is located around 2.1 miles (3.4 km) away from the city centre, and they get off the coach at Prague, Central Train Station, located 1.8 miles (2.9 km) away from the city centre.
To find the cheapest bus tickets for your trip from Mainz to Prague, follow these tips:
Start your search now and compare ticket prices to find the best deal!
popular bus stations
Important Stations and Airports in Mainz and Prague
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- Bus: 131, 174, 180 Metro: A Train: S4, S5
Most popular bus connections from Mainz
More options for your journey from Mainz to Prague
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