- Recommended
Museo dell'Opera del Duomo
The cathedral complex museum displays sculptures, silverwork and treasures from the monuments, helping visitors understand Pisa’s artistic heritage.
Cheapest price
£17
Average price
£22
Fastest journey
3 h 30 m
Average duration
3 h 47 m
Trains per day
4
Distance
262 km
The best way to find a cheap train ticket from Vatican to Pisa is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Vatican to Pisa will cost around £22 if you buy it on the day, but you can find cheap train tickets today for only £17.
Of the 4 trains that leave Vatican for Pisa every day 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct trains cover the 262 km distance in an average of 3 h 47 m but if you time it right, some trains will get you there in just 3 h 30 m .
The slowest trains will take 3 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.








Omio recommends booking the train as it is the most popular option from Vatican to Pisa among Omio's users. If you are prioritising price take the coach with prices starting from £10. For those with little time consider booking a train which can get you there in 3h 6m. The ticket price range depends on the travel mode: a coach costs an average of £10, and a train costs an average of £15.
Distance: 262 km
Most popular Train | Coach |
|---|---|
£21 Average Price | £14 Average Price Cheapest |
3h 36m Average total duration Fastest 3h 6m Onboard + 30m Additional time* | 6h 1m Average total duration 5h 31m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
The table below shows live departures for Vatican to Pisa trains for today, Thursday 13 August. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
Regionale 4122 | 6:20 Rome S. Pietro | 3h58 | 10:18 Pisa Centrale | 0 changesdirect | |
Regionale 4122+ FRECCIAROSSA 8606 | 6:20 Rome S. Pietro | 3h21 | 9:41 Pisa Centrale | 1 change | |
Regionale 4503+ FRECCIAROSSA 9490+ Regionale Veloce 4021 | 7:28 Rome S. Pietro | 4h00 | 11:28 Pisa Centrale | 2 changes | |
Regionale 12575 · Regionale Veloce 4098 · Regionale Veloce 4031 | 7:40 Rome S. Pietro | 6h11 | 13:51 Pisa Centrale | 2 changes | |
Regionale 12513+ FRECCIAROSSA 9520+ Regionale Veloce 4023 | 7:54 Rome S. Pietro | 3h57 | 11:51 Pisa Centrale | 2 changes | |
Regionale 4509+ FRECCIAROSSA 9414+ Regionale Veloce 4027 | 8:26 Rome S. Pietro | 3h59 | 12:25 Pisa Centrale | 2 changes | |
Regionale Veloce 4125+ FRECCIAROSSA 9416+ Regionale Veloce 4029 | 9:23 Rome S. Pietro | 4h05 | 13:28 Pisa Centrale | 2 changes | |
Regionale 20359+ Intercity 510 | 9:37 Rome Balduina | 4h07 | 13:44 Pisa Centrale | 1 change | |
Regionale 20359+ Intercity 510 | 9:43 Valle Aurelia | 4h01 | 13:44 Pisa Centrale | 1 change | |
Regionale 23253 · Regionale Veloce 4130 | 10:04 Rome Balduina | 4h31 | 14:35 Pisa Centrale | 1 change | |
Regionale 23253 · Regionale Veloce 4130+ Intercity 510 | 10:04 Rome Balduina | 3h40 | 13:44 Pisa Centrale | 2 changes | |
Regionale 23253 · Regionale Veloce 4130+ Intercity 510 | 10:10 Valle Aurelia | 3h34 | 13:44 Pisa Centrale | 2 changes | |
Regionale 23253 · Regionale Veloce 4130 | 10:10 Valle Aurelia | 4h25 | 14:35 Pisa Centrale | 1 change | |
Regionale Veloce 4130+ Intercity 510 | 10:32 Rome S. Pietro | 3h12 | 13:44 Pisa Centrale | 1 change | |
Regionale Veloce 4130 | 10:32 Rome S. Pietro | 4h03 | 14:35 Pisa Centrale | 0 changesdirect | |
Regionale 23327+ Intercity 590 | 11:04 Rome Balduina | 4h18 | 15:22 Pisa Centrale | 1 change | |
Regionale 23327 · Regionale 12516+ FRECCIABIANCA 8616 | 11:04 Rome Balduina | 3h45 | 14:49 Pisa Centrale | 2 changes | |
Regionale 23327+ Intercity 590 | 11:10 Valle Aurelia | 4h12 | 15:22 Pisa Centrale | 1 change | |
Regionale 23327 · Regionale 12516+ FRECCIABIANCA 8616 | 11:10 Valle Aurelia | 3h39 | 14:49 Pisa Centrale | 2 changes | |
Regionale 23327+ Intercity 590 | 11:13 Rome S. Pietro | 4h09 | 15:22 Pisa Centrale | 1 change | |
Regionale 12516+ FRECCIABIANCA 8616 | 11:32 Rome S. Pietro | 3h17 | 14:49 Pisa Centrale | 1 change | |
Regionale 12583+ FRECCIAROSSA 9584+ Regionale Veloce 4037 | 11:39 Rome S. Pietro | 4h12 | 15:51 Pisa Centrale | 2 changes | |
Regionale 23257 · Regionale Veloce 34476 | 12:04 Rome Balduina | 4h14 | 16:18 Pisa Centrale | 1 change | |
Regionale 23257 · Regionale Veloce 34476 | 12:10 Valle Aurelia | 4h08 | 16:18 Pisa Centrale | 1 change | |
Regionale Veloce 34476 | 12:33 Rome S. Pietro | 3h45 | 16:18 Pisa Centrale | 0 changesdirect | |
Regionale 23259 · Regionale 4500+ Intercity 684 | 13:04 Rome Balduina | 4h35 | 17:39 Pisa Centrale | 2 changes | |
Regionale 23259 · Regionale 4500+ FRECCIABIANCA 8620 | 13:04 Rome Balduina | 3h49 | 16:53 Pisa Centrale | 2 changes | |
Regionale 23259 · Regionale 4500+ Intercity 684 | 13:10 Valle Aurelia | 4h29 | 17:39 Pisa Centrale | 2 changes | |
Regionale 23259 · Regionale 4500+ FRECCIABIANCA 8620 | 13:10 Valle Aurelia | 3h43 | 16:53 Pisa Centrale | 2 changes | |
Regionale 4500+ Intercity 684 | 13:33 Rome S. Pietro | 4h06 | 17:39 Pisa Centrale | 1 change | |
Regionale 4500+ FRECCIABIANCA 8620 | 13:33 Rome S. Pietro | 3h20 | 16:53 Pisa Centrale | 1 change | |
Regionale 12663+ FRECCIAROSSA 9544+ Regionale Veloce 4045 | 13:52 Rome S. Pietro | 3h59 | 17:51 Pisa Centrale | 2 changes | |
Regionale 23261 · Regionale Veloce 4134 | 14:04 Rome Balduina | 4h21 | 18:25 Pisa Centrale | 1 change | |
Regionale 23261 · Regionale Veloce 4134 | 14:10 Valle Aurelia | 4h15 | 18:25 Pisa Centrale | 1 change | |
Regionale Veloce 4134 | 14:32 Rome S. Pietro | 3h53 | 18:25 Pisa Centrale | 0 changesdirect | |
Regionale 21247+ Intercity 596 | 14:34 Rome Balduina | 4h12 | 18:46 Pisa Centrale | 1 change | |
Regionale 21247+ Intercity 596 | 14:40 Valle Aurelia | 4h06 | 18:46 Pisa Centrale | 1 change | |
Regionale 12549+ Intercity 596 | 14:55 Rome S. Pietro | 3h51 | 18:46 Pisa Centrale | 1 change | |
Regionale 21357+ Intercity 518 | 15:34 Rome Balduina | 3h29 | 19:03 Pisa Centrale | 1 change | |
Regionale 21357+ Intercity 518 | 15:40 Valle Aurelia | 3h23 | 19:03 Pisa Centrale | 1 change | |
Regionale 21357+ Intercity 518 | 15:43 Rome S. Pietro | 3h20 | 19:03 Pisa Centrale | 1 change | |
Regionale 23265 · Regionale Veloce 4136 | 16:04 Rome Balduina | 4h25 | 20:29 Pisa Centrale | 1 change | |
Regionale 23265 · Regionale Veloce 4136+ FRECCIABIANCA 8626 | 16:04 Rome Balduina | 3h49 | 19:53 Pisa Centrale | 2 changes | |
Regionale 23265 · Regionale Veloce 4136 | 16:10 Valle Aurelia | 4h19 | 20:29 Pisa Centrale | 1 change | |
Regionale 23265 · Regionale Veloce 4136+ FRECCIABIANCA 8626 | 16:10 Valle Aurelia | 3h43 | 19:53 Pisa Centrale | 2 changes | |
Regionale Veloce 4136 | 16:32 Rome S. Pietro | 3h57 | 20:29 Pisa Centrale | 0 changesdirect | |
Regionale Veloce 4136+ FRECCIABIANCA 8626 | 16:32 Rome S. Pietro | 3h21 | 19:53 Pisa Centrale | 1 change | |
Regionale 21373 · Regionale 12540+ FRECCIABIANCA 8630 | 17:35 Rome Balduina | 3h45 | 21:20 Pisa Centrale | 2 changes | |
Regionale 21373 · Regionale 12540+ FRECCIABIANCA 8630 | 17:41 Valle Aurelia | 3h39 | 21:20 Pisa Centrale | 2 changes | |
Regionale 12540+ FRECCIABIANCA 8630 | 18:02 Rome S. Pietro | 3h18 | 21:20 Pisa Centrale | 1 change | |
Regionale 23269 · Regionale Veloce 4138 | 18:04 Rome Balduina | 4h11 | 22:15 Pisa Centrale | 1 change | |
Regionale 23269 · Regionale Veloce 4138 | 18:10 Valle Aurelia | 4h05 | 22:15 Pisa Centrale | 1 change | |
Regionale Veloce 4138 | 18:32 Rome S. Pietro | 3h43 | 22:15 Pisa Centrale | 0 changesdirect | |
Regionale 23271+ Intercity 822 | 19:04 Rome Balduina | 3h37 | 22:41 Pisa Centrale | 1 change | |
Regionale 23271+ Intercity 822 | 19:10 Valle Aurelia | 3h31 | 22:41 Pisa Centrale | 1 change | |
Regionale 23271+ Intercity 822 | 19:13 Rome S. Pietro | 3h28 | 22:41 Pisa Centrale | 1 change | |
Regionale 23305 · Regionale Veloce 4140 | 20:08 Rome Balduina | 4h07 | 0:15 Pisa Centrale | 1 change | |
Regionale 23305 · Regionale Veloce 4140 | 20:14 Valle Aurelia | 4h01 | 0:15 Pisa Centrale | 1 change | |
Regionale Veloce 4140 | 20:32 Rome S. Pietro | 3h43 | 0:15 Pisa Centrale | 0 changesdirect | |
Regionale 20519+ InterCityNotte 796 | 23:07 Rome Balduina | 4h16 | 3:23 Pisa Centrale | 1 change | |
Regionale 20519+ InterCityNotte 796 | 23:13 Valle Aurelia | 4h10 | 3:23 Pisa Centrale | 1 change | |
Regionale Veloce 4139+ InterCityNotte 796 | 23:25 Rome S. Pietro | 3h58 | 3:23 Pisa Centrale | 1 change | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train and coach prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Vatican to Pisa run on average 80 times per day, taking around 3h 6m. Cheap train tickets for this journey start at £15 but you can travel from only £10 by coach.
There are 7 trains per day. The earliest train runs at 01:05, the last at 23:52. The fastest train covers the 262 km distance in 3h 17m.
Distance 262 km |
Average train duration 3h 6m |
Cheapest ticket price £15 |
Trains per day 80 |
Direct trains 7 |
Fastest train 3h 17m |
First train 1:05 |
Last train 23:52 |
Cheapest Month May |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Mon |
Least Busy Day Sun |
Best time to book 84 days |
Discover the best of Pisa — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Pisa trip today.
The cathedral complex museum displays sculptures, silverwork and treasures from the monuments, helping visitors understand Pisa’s artistic heritage.
Set in a former monastery, this museum presents medieval and Renaissance art, including paintings, sculpture and illuminated works from Pisa and Tuscany.
Housed in the Arsenali Medicei, this museum explores ancient ships and river life with preserved vessels and engaging archaeological displays.
The famous green lawn around Pisa’s cathedral monuments is the city’s essential open space for views, photographs and a first encounter with its highlights.
Pisa’s main riverside promenade offers handsome palaces, bridges and evening walks, especially atmospheric at sunset or during local events.
A lively historic square lined with arcades and university life, ideal for people-watching and experiencing the city beyond the tower area.
Thick Tuscan bread soup with black cabbage, beans and vegetables. A frugal Pisan staple, traditionally enriched with day-old bread and olive oil.
Toasted Tuscan bread topped with chicken liver pâté. A classic regional antipasto found in Pisa and across Tuscany.
Tuscan seafood stew of mixed fish and shellfish in tomato sauce, linked to Pisa’s maritime traditions and nearby coast.
Refined seafood restaurant close to Piazza dei Miracoli, popular for fresh fish dishes and a polished but welcoming setting.
Casual spot appreciated for cecìna, pizzas and other Tuscan specialities, with an easygoing local feel.
Traditional Pisan trattoria known for Tuscan classics and seafood, with a relaxed, rustic atmosphere near the centre.
Moderate for Italy: tourist areas cost more, but budget stays, simple meals and local buses remain fairly manageable.
Tipping is modest. Service may be included. Round up or leave €1-2 in cafés, 5-10% for very good restaurant service, and round up taxi fares.
Official public transport app
Pisa Centrale -> Piazza Vittorio Emanuele II, Pisa
Find answers to the most common questions about traveling from Vatican to Pisa by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Pisa, this guide helps you travel smarter and with confidence.

Most Vatican to Pisa trains use the Roma San Pietro to Pisa Centrale station pair, with some services arriving at Pisa San Rossore. Use this guide to compare Vatican and Pisa train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Pisa Centrale has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental and Information Desk.
Food options include: McDonald's, Panetteria Binario 1
There is free Wi-Fi available at the McDonald's.
The ticket office is open Mon - Sun: 06:00 - 20:30. Information desks are located just outside the station on Piazza Vittorio Emanuele II.
Luggage storage is there is a luggage storage office near the end of Platform 1.
Available at Pisa Centrale: Parking, Taxis, WC.
Available at Pisa Centrale: Bike Parking, Bike Rental.
Accessibility facilities are available at Pisa Centrale: Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
Nearby hotels include Hotel NH Pisa, Hotel La Pace, Hotel Maria.
Pisa San Rossore is 1 km from Pisa city centre. Public transport options include:
Pisa San Rossore has practical services for this route, including Parking, Dining, Accessibility, WC, Hotel, Ticket Office, Bike Parking and Bike Rental.
Food options include: Ristorante pizzeria, SushiKing, Ristorante Cinese Oriente
The ticket office is open 24/7.
Available at Pisa San Rossore: Parking, WC.
Available at Pisa San Rossore: Bike Parking, Bike Rental.
Accessibility facilities are available at Pisa San Rossore: Elevators on every platform. Sala Blu services can be reached at +39 0647308579.
Nearby hotels include Rosso di Sera Relais Tuscany, Le Cascine, Camping Village Torre Pendente.
Here are some other resources that might have the information you need