- Must visit
Vatican Museums
World-renowned Vatican collections with Raphael Rooms and the Sistine Chapel, essential for art and Church history.
Cheapest price on 15 Oct
£34
Average ticket price on 15 Oct
£74
Fastest journey on 15 Oct
4 h 22 m
Average journey duration on 15 Oct
4 h 50 m
Trains on 15 Oct
23
Distance
380 km
The best way to find a cheap train ticket from Santa Margherita Ligure to Rome is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Santa Margherita Ligure to Rome will cost around £74 if you buy it on the day, but you can find cheap train tickets today for only £34.
To travel from Santa Margherita Ligure to Rome you need to make at least one change.
Regionale Veloce 3265 · Regionale 19361 · Regionale Veloce 4135
Regionale 3257 · Regionale TTPER 19238 · Regionale 19351 · Regionale Veloce 4131
Regionale Veloce 3273 · Regionale 19367 · Regionale Veloce 4137
Regionale Veloce 3277+
InterCityNotte 795
Regionale 12461+
InterCityNotte 899
Regionale 12311+
FRECCIAROSSA 8551
Intercity 673+
FRECCIARGENTO 8591
Regionale 12361+
FRECCIABIANCA 8613
Regionale 12391+
FRECCIABIANCA 8619
Regionale Veloce 3277+
FRECCIAROSSA 8623Trains from Santa Margherita Ligure to Rome run on average 19 times per day, taking around 5h 31m. Cheap train tickets for this journey start at £4 if you book in advance.
The earliest train runs at 00:01, the last at 23:57. The fastest train covers the 380 km distance in 3h 43m.
Distance 380 km |
Average train duration 5h 31m |
Cheapest ticket price £4 |
Trains per day 19 |
Fastest train 3h 43m |
First train 0:01 |
Last train 23:57 |
Cheapest Month Jan |
Cheapest Day Wed |
High Season Jul - Sept |
Low Season Oct - Dec |
Busiest Day Sat |
Least Busy Day Wed |
Best time to book 21 days |
The table below shows live departures for Santa Margherita Ligure to Rome trains for today, Wednesday 14 October. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
Regionale 12461+ InterCityNotte 899 | 22:06 Santa Margherita Ligure-Portofino | 7h37 | 5:43 Rome Ostiense | 1 change | |
| Thursday 15 October | |||||
treno 3288 effettuato con bus GE034+ 9998 | 1:02 Santa Margherita Ligure-Portofino | 10h23 | 11:25 Rome Termini | 1 change | |
Regionale Veloce 3016+ FRECCIARGENTO 8583 | 4:55 Santa Margherita Ligure-Portofino | 5h15 | 10:10 Rome Termini | 1 change | |
Regionale Veloce 3016+ 9998 | 4:55 Santa Margherita Ligure-Portofino | 6h30 | 11:25 Rome Termini | 1 change | |
Regionale 3257 · Regionale TTPER 19238 · Regionale 19351 · Regionale Veloce 4131 | 6:37 Santa Margherita Ligure-Portofino | 9h11 | 15:48 Rome Termini | 3 changes | |
Regionale 12311+ FRECCIAROSSA 8551 | 7:12 Santa Margherita Ligure-Portofino | 4h22 | 11:34 Rome Termini | 1 change | |
Intercity 658+ FRECCIAROSSA 9623 | 7:39 Santa Margherita Ligure-Portofino | 6h31 | 14:10 Rome Termini | 1 change | |
Intercity 651+ Regionale Veloce 4026+ FRECCIAROSSA 9411 | 8:24 Santa Margherita Ligure-Portofino | 5h11 | 13:35 Rome Termini | 2 changes | |
Regionale 12331+ Intercity 505 | 8:59 Santa Margherita Ligure-Portofino | 5h34 | 14:33 Rome Termini | 1 change | |
Regionale Veloce 3265 · Regionale 19361 · Regionale Veloce 4135 | 11:15 Santa Margherita Ligure-Portofino | 8h33 | 19:48 Rome Termini | 2 changes | |
Regionale 12361+ FRECCIABIANCA 8613 | 12:05 Santa Margherita Ligure-Portofino | 4h58 | 17:03 Rome Termini | 1 change | |
Regionale 12367+ Intercity 511 | 12:38 Santa Margherita Ligure-Portofino | 5h25 | 18:03 Rome Termini | 1 change | |
Regionale Veloce 3266 · Regionale Veloce 3032+ FRECCIAROSSA 9645 | 12:46 Santa Margherita Ligure-Portofino | 6h29 | 19:15 Rome Termini | 2 changes | |
Regionale Veloce 3269 · Regionale 18415+ FRECCIAROSSA 9427 | 13:15 Santa Margherita Ligure-Portofino | 6h10 | 19:25 Rome Termini | 2 changes | |
Regionale Veloce 3269 · Regionale 18415+ Intercity 597 | 13:15 Santa Margherita Ligure-Portofino | 7h52 | 21:07 Rome Tiburtina | 2 changes | |
Intercity 670+ FRECCIAROSSA 9647 | 13:46 Santa Margherita Ligure-Portofino | 5h54 | 19:40 Rome Termini | 1 change | |
Regionale 12391+ FRECCIABIANCA 8619 | 15:02 Santa Margherita Ligure-Portofino | 5h01 | 20:03 Rome Termini | 1 change | |
Regionale Veloce 3273 · Regionale 19367 · Regionale Veloce 4137 | 15:15 Santa Margherita Ligure-Portofino | 6h33 | 21:48 Rome Termini | 2 changes | |
Regionale Veloce 3273 · Regionale 18401+ FRECCIAROSSA 8527 | 15:15 Santa Margherita Ligure-Portofino | 6h00 | 21:15 Rome Termini | 2 changes | |
Intercity 674+ FRECCIAROSSA 9657 | 15:46 Santa Margherita Ligure-Portofino | 5h54 | 21:40 Rome Termini | 1 change | |
Regionale Veloce 3277+ InterCityNotte 795 | 17:15 Santa Margherita Ligure-Portofino | 6h08 | 23:23 Rome Ostiense | 1 change | |
Regionale Veloce 3277+ FRECCIAROSSA 8623 | 17:15 Santa Margherita Ligure-Portofino | 5h03 | 22:18 Rome Termini | 1 change | |
Intercity 673+ FRECCIARGENTO 8591 | 18:16 Santa Margherita Ligure-Portofino | 4h45 | 23:01 Rome Termini | 1 change | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-renowned Vatican collections with Raphael Rooms and the Sistine Chapel, essential for art and Church history.
Superb Capitoline collections on Michelangelo's square, showcasing ancient sculpture, bronzes, and Rome's civic history.
Outstanding gallery in a villa setting, celebrated for Bernini sculptures and masterpieces by Caravaggio and Raphael.
Baroque square with fountains and lively street life, ideal for people-watching and a classic Rome atmosphere.
Famous staircase linking Piazza di Spagna to Trinità dei Monti, beloved for city scenes and elegant surroundings.
Bohemian quarter of lanes, piazzas, and nightlife, popular for evening strolls, local character, and riverside charm.
Roman pasta with guanciale, egg yolk, Pecorino Romano and black pepper. A city icon prized for its rich sauce and no cream tradition.
Pasta in a sharp, savoury sauce of guanciale, tomato and Pecorino Romano. A classic Roman favourite with roots in local trattoria cooking.
Simple Roman pasta made with Pecorino Romano and black pepper. It shows the city’s love of bold flavour from few ingredients.
Michelin-starred restaurant by the Colosseum serving refined Roman cuisine in an elegant setting. Best for a fine-dining splurge.
Historic Trastevere trattoria known for classic Roman pasta and warm old-school rooms. A dependable choice for traditional local dishes.
Long-running Testaccio restaurant specialising in Roman quinto quarto and pasta. Informal, authentic and popular with locals and visitors.
Moderate for a major Western European capital. Hotels in central areas are pricey, but dining and public transport are often cheaper than in Paris or London.
Service is often included or covered by a coperto. Rounding up or leaving 5-10% is appreciated in restaurants. In cafés, small change is enough; taxis are usually rounded up.
Official public transport app
Roma Termini -> Piazza Venezia, Rome
The most popular day trips by train from Rome are Florence, Naples, Orvieto, Tivoli and Viterbo. Find out what you can do in these day trip destinations and how to book your train from Rome on Omio.

Florence is known for Renaissance art and architecture, with the Duomo and Ponte Vecchio shaping its skyline. Despite its fame, it feels compact and lived-in, with busy piazzas, artisan workshops and a strong Tuscan food culture.
There are 134 trains per day. The earliest train runs at 00:09, the last at 23:54. The fastest train covers the 231 km distance in 1h 16m.

Naples is a lively city on the Bay of Naples, known for pizza, faded grandeur and the presence of Vesuvius. Its historic centre is dense and energetic, where churches, street life and sea views sit close together.
There are 110 trains per day. The earliest train runs at 00:19, the last at 23:56. The fastest train covers the 189 km distance in 1h 6m.

Orvieto is known for its dramatic Duomo, Etruscan heritage and position on volcanic cliffs. Medieval streets, underground spaces and a calm Umbrian atmosphere give it a distinct character.
There are 13 trains per day. The earliest train runs at 00:02, the last at 23:55. The fastest train covers the 97 km distance in 59m.

Tivoli is a hillside town east of Rome known for Villa d’Este and Hadrian’s Villa. Its historic centre feels lived-in and calm, with stone streets, fountains and broad views over the surrounding countryside.
There are 25 trains per day. The earliest train runs at 04:30, the last at 22:32. The fastest train covers the 27 km distance in 33m.

Viterbo is a medieval city in Lazio known for its papal history, stone streets and nearby thermal springs. The old quarter gathers towers, piazzas and the Palazzo dei Papi, giving the city a distinctly historic character.
There are 31 trains per day. The earliest train runs at 04:55, the last at 22:47. The fastest train covers the 66 km distance in 1h 27m.
Find answers to the most common questions about traveling from Santa Margherita Ligure to Rome by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Santa Margherita Ligure to Rome trains use the S. Margherita Ligure-Portofino to Roma Termini station pair, with some services arriving at Roma Ostiense. Use this guide to compare Santa Margherita Ligure and Rome train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
S. Margherita Ligure-Portofino has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Information Desk and Luggage Carts.
Food options include: Ristorante Da Michele, Trattoria Baicin
Free.
Ticket office support is available at S. Margherita Ligure-Portofino. Information desks are located in the main hall.
Luggage storage is available at S. Margherita Ligure-Portofino. Lost and found is available at the station.
Available at S. Margherita Ligure-Portofino: Parking, Taxis, WC.
Available at S. Margherita Ligure-Portofino: Bike Parking, Bike Rental.
Accessibility facilities are available at S. Margherita Ligure-Portofino: Elevators, ramps, restrooms.
Nearby hotels include Hotel Laurin, Hotel Metropole, Hotel Jolanda.
Roma Termini is 1 km from Rome city centre. Public transport options include:
Roma Termini has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Car Rental and Information Desk.
Food options include: Acafe, Moka Café, Roadhouse Grill, McDonald's, Gusto, Chef Express, Coop Minimarket, Mercato Centrale
Free WiFi in the station. ATMs are there are ATMs in various locations around the station.
The ticket office is open Mon - Sun: 06:30 - 22:00. Information desks are located near Platform 24.
Luggage storage is provided by KiPoint and located on Platform 24. Open every day from 06:00 to 23:00.
Available at Roma Termini: Parking, Taxis, WC.
Available at Roma Termini: Bike Parking, Car Rental.
Accessibility facilities are available at Roma Termini: The Sala Blu, Trenitalia's office of assistance for disabled travelers, is located next to Platform 1.
Nearby hotels include Archi di Roma Guest House, Gemma di Roma, The Liberty Boutique Hotel.
Roma Ostiense is 2 km from Rome city centre. Public transport options include:
Roma Ostiense has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk and Luggage Carts.
Food options include: Ramen Bar Akira, Eataly Roma
Free. ATMs are available in the train station.
Ticket office support is available at Roma Ostiense. Information desks are located in the main hall.
Luggage storage is available at Roma Ostiense. Lost and found is available at the station.
Available at Roma Ostiense: Parking, Taxis, WC.
Available at Roma Ostiense: Bike Parking, Car Rental.
Accessibility facilities are available at Roma Ostiense: Elevators, ramps, restrooms.
Nearby hotels include Hotel Abitart, Hotel San Anselmo, Hotel Villa San Pio.
Roma Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma Tiburtina has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Car Rental and Information Desk.
Food options include: Rock n’ Coffee Roma, Arabian Kebab, Ingredienti, McDonald’s, Numb's Bakery Café
Free, limited Wi-Fi available in the station for 15 minutes. ATMs are located on the ground floor level.
The ticket office is open Mon - Sun: 06:35 - 20:20. Information desks are located inside the main terminal. .
Luggage storage is luggage lockers are located in the station lobby.
Available at Roma Tiburtina: Parking, Taxis, WC.
Available at Roma Tiburtina: Bike Parking, Car Rental.
Accessibility facilities are available at Roma Tiburtina: Accessible facilities include elevators and escalators.
Nearby hotels include B&B Rome Tiburtina, B&B Alba Domus Roma, Hotel delle Province.
Here are some other resources that might have the information you need