The cheapest and fastest trains from Rome Ostiense to Milan Centrale
Cheapest price
£65
Average price
£65
Fastest journey
7 h 28 m
Average duration
7 h 28 m
Trains per day
1
Distance
481 km
The best way to find a cheap train ticket from Rome Ostiense to Milan Centrale is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Rome Ostiense to Milan Centrale will cost around £65 if you buy it on the day, but you can find cheap train tickets today for only £65.
Of the 1 trains that leave Rome Ostiense for Milan Centrale every day 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct trains cover the 481 km distance in an average of 7 h 28 m but if you time it right, some trains will get you there in just 7 h 28 m .
The slowest trains will take 7 h 28 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare train, coach and flight for Rome Ostiense to Milan Centrale
Omio recommends booking the train as it is the most popular option from Rome Ostiense to Milan Centrale among Omio's users. If you are prioritising price take the coach with prices starting from £6. For those with little time consider booking a flight which can get you there in 1h 14m. The ticket price range depends on the travel mode: a coach costs an average of £6, and a flight costs an average of £46.
Distance: 481 km
Compare train with
Most popular Train | Coach | Flight |
|---|---|---|
£50 Average Price | £22 Average Price Cheapest | £87 Average Price |
5h 30m Average total duration 5h 0m Onboard + 30m Additional time* | 8h 29m Average total duration 7h 59m Onboard + 30m Additional time* | 4h 14m Average total duration Fastest 1h 14m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Rome Ostiense to Milan Centrale train times
The table below shows live departures for Rome Ostiense to Milan Centrale trains for today, Tuesday 3 February. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
Intercity 510 · Intercity 635 | 09:38 Rome Ostiense | 8h17 | 17:55 Milan Centrale | 1 change | |
Regionale 12781+ FRECCIAROSSA 1000 9628 | 09:39 Rome Ostiense | 3h56 | 13:35 Milan Centrale | 1 change | |
Regionale 12781+ 9928 | On time 09:39 Rome Ostiense | 4h41 | 14:20 Milan Centrale | 1 change | |
Regionale 12781+ 9982 | On time 09:39 Rome Ostiense | 5h36 | 15:15 Milan Centrale | 1 change | |
Regionale 12781+ 9978 | On time 09:39 Rome Ostiense | 3h36 | 13:15 Milan Centrale | 1 change | |
Regionale 20481+ FRECCIAROSSA 1000 9514 | 09:46 Rome Ostiense | 4h04 | 13:50 Milan Centrale | 1 change | |
Regionale 12531+ 9982 | On time 10:07 Rome Ostiense | 5h08 | 15:15 Milan Centrale | 1 change | |
Regionale 12531+ 9932 | 10:07 Rome Ostiense | 5h13 | 15:20 Milan Centrale | 1 change | |
Regionale 12531+ FRECCIAROSSA 1000 9630 | 10:07 Rome Ostiense | 3h51 | 13:58 Milan Centrale | 1 change | |
Regionale 12531+ 9928 | On time 10:07 Rome Ostiense | 4h13 | 14:20 Milan Centrale | 1 change | |
ETRUSCHI LINE 12589+ 9984 | 10:37 Rome Ostiense | 5h38 | 16:15 Milan Centrale | 1 change | |
ETRUSCHI LINE 12589+ 9982 | On time 10:37 Rome Ostiense | 4h38 | 15:15 Milan Centrale | 1 change | |
ETRUSCHI LINE 12589+ 9932 | 10:37 Rome Ostiense | 4h43 | 15:20 Milan Centrale | 1 change | |
Regionale 12583+ FRECCIAROSSA 1000 9632 | 10:51 Rome Ostiense | 3h44 | 14:35 Milan Centrale | 1 change | |
Regionale 12583+ 9932 | 10:51 Rome Ostiense | 4h29 | 15:20 Milan Centrale | 1 change | |
Regionale 12583+ 9982 | On time 10:51 Rome Ostiense | 4h24 | 15:15 Milan Centrale | 1 change | |
Regionale 12583+ 9984 | 10:51 Rome Ostiense | 5h24 | 16:15 Milan Centrale | 1 change | |
Regionale 20345+ Intercity 590 | 11:07 Rome Ostiense | 7h18 | 18:25 Milan Centrale | 1 change | |
Regionale 12539+ FRECCIAROSSA 9636 | 11:39 Rome Ostiense | 3h51 | 15:30 Milan Centrale | 1 change | |
Regionale 12539+ 9982 | On time 11:39 Rome Ostiense | 3h36 | 15:15 Milan Centrale | 1 change | |
Regionale 12539+ 8134 | On time 11:39 Rome Ostiense | 4h41 | 16:20 Milan Centrale | 1 change | |
Regionale 12539+ 9984 | 11:39 Rome Ostiense | 4h36 | 16:15 Milan Centrale | 1 change | |
Regionale 12541+ 9986 | On time 12:07 Rome Ostiense | 5h08 | 17:15 Milan Centrale | 1 change | |
Regionale 12541+ 8134 | On time 12:07 Rome Ostiense | 4h13 | 16:20 Milan Centrale | 1 change | |
Regionale 12541+ FRECCIAROSSA 1000 9638 | 12:07 Rome Ostiense | 3h51 | 15:58 Milan Centrale | 1 change | |
Regionale 12541+ 9984 | 12:07 Rome Ostiense | 4h08 | 16:15 Milan Centrale | 1 change | |
Regionale 4500+ Intercity 684 | 12:23 Rome Ostiense | 8h32 | 20:55 Milan Centrale | 1 change | |
Regionale 12543+ 9940 | 12:39 Rome Ostiense | 4h41 | 17:20 Milan Centrale | 1 change | |
Regionale 12543+ 9986 | On time 12:39 Rome Ostiense | 4h36 | 17:15 Milan Centrale | 1 change | |
Regionale 12543+ FRECCIAROSSA 1000 9640 | 12:39 Rome Ostiense | 3h51 | 16:30 Milan Centrale | 1 change | |
Regionale 12543+ 9984 | 12:39 Rome Ostiense | 3h36 | 16:15 Milan Centrale | 1 change | |
Regionale 20657+ FRECCIAROSSA 9540 | 12:46 Rome Ostiense | 4h04 | 16:50 Milan Centrale | 1 change | |
Regionale 12663+ 9986 | On time 13:07 Rome Ostiense | 4h08 | 17:15 Milan Centrale | 1 change | |
Regionale 12663+ 9940 | 13:07 Rome Ostiense | 4h13 | 17:20 Milan Centrale | 1 change | |
Regionale 12663+ FRECCIAROSSA 1000 9642 | 13:07 Rome Ostiense | 3h51 | 16:58 Milan Centrale | 1 change | |
Regionale 12663+ 9950 | On time 13:07 Rome Ostiense | 5h08 | 18:15 Milan Centrale | 1 change | |
ETRUSCHI LINE 4134 · Regionale 2296 | 13:23 Rome Ostiense | 8h59 | 22:22 Milan Centrale | 1 change | |
Regionale 12547+ FRECCIAROSSA 1000 9644 | 13:39 Rome Ostiense | 3h51 | 17:30 Milan Centrale | 1 change | |
Regionale 12547+ 9950 | On time 13:39 Rome Ostiense | 4h36 | 18:15 Milan Centrale | 1 change | |
Regionale 12547+ 9986 | On time 13:39 Rome Ostiense | 3h36 | 17:15 Milan Centrale | 1 change | |
Regionale 12547+ 9946 | 13:39 Rome Ostiense | 4h41 | 18:20 Milan Centrale | 1 change | |
Regionale 12549+ 9950 | On time 14:07 Rome Ostiense | 4h08 | 18:15 Milan Centrale | 1 change | |
Regionale 12549+ 9990 | 14:07 Rome Ostiense | 5h08 | 19:15 Milan Centrale | 1 change | |
Regionale 12549+ 9946 | 14:07 Rome Ostiense | 4h13 | 18:20 Milan Centrale | 1 change | |
Regionale 12549+ FRECCIAROSSA 1000 9646 | 14:07 Rome Ostiense | 3h53 | 18:00 Milan Centrale | 1 change | |
Regionale 20771+ Intercity 596 | 14:16 Rome Ostiense | 8h01 | 22:17 Milan Centrale | 1 change | |
ETRUSCHI LINE 4131+ FRECCIAROSSA 1000 9648 | 14:37 Rome Ostiense | 3h47 | 18:24 Milan Centrale | 1 change | |
ETRUSCHI LINE 4131+ 9990 | 14:37 Rome Ostiense | 4h38 | 19:15 Milan Centrale | 1 change | |
ETRUSCHI LINE 4131+ 9948 | 14:37 Rome Ostiense | 4h43 | 19:20 Milan Centrale | 1 change | |
ETRUSCHI LINE 4131+ 9950 | On time 14:37 Rome Ostiense | 3h38 | 18:15 Milan Centrale | 1 change | |
Regionale 20677+ FRECCIAROSSA 9588 | 14:46 Rome Ostiense | 4h04 | 18:50 Milan Centrale | 1 change | |
Intercity 518+ Regionale Veloce 3047 | 15:07 Rome Ostiense | 7h28 | 22:35 Milan Centrale | 1 change | |
Regionale 12551+ 9948 | 15:07 Rome Ostiense | 4h13 | 19:20 Milan Centrale | 1 change | |
Regionale 12551+ 9992 | 15:07 Rome Ostiense | 5h08 | 20:15 Milan Centrale | 1 change | |
Regionale 12551+ 9990 | 15:07 Rome Ostiense | 4h08 | 19:15 Milan Centrale | 1 change | |
Regionale 12551+ FRECCIAROSSA 1000 9650 | 15:07 Rome Ostiense | 3h51 | 18:58 Milan Centrale | 1 change | |
Regionale 12585+ 9958 | 15:40 Rome Ostiense | 4h40 | 20:20 Milan Centrale | 1 change | |
Regionale 12585+ FRECCIAROSSA 1000 9652 | 15:40 Rome Ostiense | 3h50 | 19:30 Milan Centrale | 1 change | |
Regionale 12585+ 9990 | 15:40 Rome Ostiense | 3h35 | 19:15 Milan Centrale | 1 change | |
Regionale 12585+ 9992 | 15:40 Rome Ostiense | 4h35 | 20:15 Milan Centrale | 1 change | |
Regionale 12553+ 9944 | 16:07 Rome Ostiense | 4h38 | 20:45 Milan Centrale | 1 change | |
Regionale 12553+ 9992 | 16:07 Rome Ostiense | 4h08 | 20:15 Milan Centrale | 1 change | |
Regionale 12553+ 9958 | 16:07 Rome Ostiense | 4h13 | 20:20 Milan Centrale | 1 change | |
Regionale 12553+ FRECCIAROSSA 9658 | 16:07 Rome Ostiense | 3h53 | 20:00 Milan Centrale | 1 change | |
ETRUSCHI LINE 4133+ 9944 | 16:37 Rome Ostiense | 4h08 | 20:45 Milan Centrale | 1 change | |
ETRUSCHI LINE 4133+ 9994 | On time 16:37 Rome Ostiense | 4h38 | 21:15 Milan Centrale | 1 change | |
ETRUSCHI LINE 4133+ 9992 | 16:37 Rome Ostiense | 3h38 | 20:15 Milan Centrale | 1 change | |
Regionale 12723+ 9954 | 17:06 Rome Ostiense | 4h14 | 21:20 Milan Centrale | 1 change | |
Regionale 12723+ 9994 | On time 17:06 Rome Ostiense | 4h09 | 21:15 Milan Centrale | 1 change | |
Regionale 12723+ 9996 | On time 17:06 Rome Ostiense | 5h09 | 22:15 Milan Centrale | 1 change | |
Regionale 12587+ 8158 | 17:23 Rome Ostiense | 4h57 | 22:20 Milan Centrale | 1 change | |
Regionale 12587+ FRECCIAROSSA 1000 9662 | 17:23 Rome Ostiense | 3h37 | 21:00 Milan Centrale | 1 change | |
Regionale 12587+ 9996 | On time 17:23 Rome Ostiense | 4h52 | 22:15 Milan Centrale | 1 change | |
Regionale 12587+ 9994 | On time 17:23 Rome Ostiense | 3h52 | 21:15 Milan Centrale | 1 change | |
Regionale 4511+ 9994 | On time 17:39 Rome Ostiense | 3h36 | 21:15 Milan Centrale | 1 change | |
Regionale 4511+ 8158 | 17:39 Rome Ostiense | 4h41 | 22:20 Milan Centrale | 1 change | |
Regionale 4511+ 9996 | On time 17:39 Rome Ostiense | 4h36 | 22:15 Milan Centrale | 1 change | |
Regionale 20715+ FRECCIAROSSA 1000 9560 | 17:46 Rome Ostiense | 4h04 | 21:50 Milan Centrale | 1 change | |
Regionale 12573+ FRECCIAROSSA 9668 | 18:07 Rome Ostiense | 3h53 | 22:00 Milan Centrale | 1 change | |
Regionale 12573+ 9996 | On time 18:07 Rome Ostiense | 4h08 | 22:15 Milan Centrale | 1 change | |
Regionale 12573+ 9962 | 18:07 Rome Ostiense | 5h13 | 23:20 Milan Centrale | 1 change | |
Regionale 12573+ 8158 | 18:07 Rome Ostiense | 4h13 | 22:20 Milan Centrale | 1 change | |
ETRUSCHI LINE 4135+ FRECCIAROSSA 9592 | 18:37 Rome Ostiense | 4h13 | 22:50 Milan Centrale | 1 change | |
ETRUSCHI LINE 4135+ 9962 | 18:37 Rome Ostiense | 4h43 | 23:20 Milan Centrale | 1 change | |
ETRUSCHI LINE 4135+ 9996 | On time 18:37 Rome Ostiense | 3h38 | 22:15 Milan Centrale | 1 change | |
Regionale 12559+ 9962 | 19:07 Rome Ostiense | 4h13 | 23:20 Milan Centrale | 1 change | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome Ostiense to Milan Centrale by train, coach or flight
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Rome Ostiense to Milan Centrale
Trains from Rome Ostiense to Milan Centrale run on average 27 times per day, taking around 5h 0m. Cheap train tickets for this journey start at £17 but you can travel from only £6 by coach.
There are 1 trains per day. The earliest train runs at 10:01, the last at 21:53. The fastest train covers the 481 km distance in 3h 53m.
Distance 481 km |
Average train duration 5h 0m |
Cheapest ticket price £17 |
Trains per day 27 |
Direct trains 1 |
Fastest train 3h 53m |
First train 10:01 |
Last train 21:53 |
Train companies: Italo, Frecciarossa, Intercity Notte, Intercity, Regionale from Rome Ostiense to Milan Centrale trainsItalo, Frecciarossa, Intercity Notte, Intercity, Regionale trains will get you between Rome Ostiense and Milan Centrale from £6. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Frecciarossa
Intercity Notte
Intercity
Regionale
FAQs: Rome Ostiense to Milan Centrale train
Find answers to the most common questions about traveling from Rome Ostiense to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Rome Ostiense and Milan Centrale
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available near the station with both short-term and long-term options.
- Ramen Bar Akira
- Eataly Roma
- Outside the main entrance.
- Elevators, ramps, restrooms.
- €1
- Hotel Abitart
- Hotel San Anselmo
- Hotel Villa San Pio
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-5 for regional and intercity trains
- Hall 2: platforms 6-11 for metropolitan services
- Metro: Line B
- Bus: Several lines available
- Tram: Line 3
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Rome Ostiense
More options for your journey from Rome Ostiense to Milan Centrale
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