The cheapest and fastest trains from Rome Ostiense to Milan Centrale
Cheapest price
£35
Average price
£38
Fastest journey
4 h 13 m
Average duration
6 h 38 m
Trains per day
2
Distance
481 km
The best way to find a cheap train ticket from Rome Ostiense to Milan Centrale is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Rome Ostiense to Milan Centrale will cost around £38 if you buy it on the day, but you can find cheap train tickets today for only £35.
Of the 2 trains that leave Rome Ostiense for Milan Centrale every day 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct trains cover the 481 km distance in an average of 6 h 38 m but if you time it right, some trains will get you there in just 4 h 13 m .
The slowest trains will take 9 h 2 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
18:374h13Rome Ostiense22:50Milan Centrale£351One-way0 changes
13:239h02Rome Ostiense22:25Milan Centrale£411One-way0 changes
18:374h13Rome Ostiense22:50Milan Centrale£351One-way0 changes
13:239h02Rome Ostiense22:25Milan Centrale£411One-way0 changes
Travel Information
Compare train, coach and flight for Rome Ostiense to Milan Centrale
Omio recommends booking the train as it is the most popular option from Rome Ostiense to Milan Centrale among Omio's users. If you are prioritising price take the coach with prices starting from £6. For those with little time consider booking a flight which can get you there in 1h 14m. The ticket price range depends on the travel mode: a coach costs an average of £6, and a flight costs an average of £47.
Distance: 481 km
Compare train with
Most popular Train | Coach | Flight |
|---|---|---|
£41 Average Price | £12 Average Price Cheapest | £78 Average Price |
6h 10m Average total duration 5h 40m Onboard + 30m Additional time* | 8h 29m Average total duration 7h 59m Onboard + 30m Additional time* | 4h 14m Average total duration Fastest 1h 14m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Rome Ostiense to Milan Centrale train times
The table below shows live departures for Rome Ostiense to Milan Centrale trains for today, Monday 4 May. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
Regionale 12587+ FRECCIAROSSA 9662 | 18:23 Rome Ostiense | 3h37 | 22:00 Milan Centrale | 1 change | |
Regionale 12587+ 8158 | Delayed 18:23 Rome Ostiense | 4h57 | 21:21 21:21Milan Centrale | 1 change | |
Regionale 12587+ 9996 | On time 18:23 Rome Ostiense | 4h52 | 23:15 Milan Centrale | 1 change | |
Regionale 12587+ 9962 | 18:23 Rome Ostiense | 5h57 | 0:20 Milan Centrale | 1 change | |
Regionale 4511+ 8158 | Delayed 18:39 Rome Ostiense | 4h41 | 21:21 21:21Milan Centrale | 1 change | |
Regionale 4511+ 9962 | 18:39 Rome Ostiense | 5h41 | 0:20 Milan Centrale | 1 change | |
Regionale 4511+ 9996 | On time 18:39 Rome Ostiense | 4h36 | 23:15 Milan Centrale | 1 change | |
Regionale 20715+ FRECCIAROSSA 9560 | 18:46 Rome Ostiense | 4h04 | 22:50 Milan Centrale | 1 change | |
Regionale 12573+ 9962 | 19:07 Rome Ostiense | 5h13 | 0:20 Milan Centrale | 1 change | |
Regionale 12573+ FRECCIAROSSA 9668 | 19:07 Rome Ostiense | 3h53 | 23:00 Milan Centrale | 1 change | |
Regionale 12573+ 9996 | On time 19:07 Rome Ostiense | 4h08 | 23:15 Milan Centrale | 1 change | |
Regionale 12573+ 8158 | Delayed 19:07 Rome Ostiense | 4h13 | 21:21 21:21Milan Centrale | 1 change | |
Regionale Veloce 4135+ FRECCIAROSSA 9592 | 19:37 Rome Ostiense | 4h13 | 23:50 Milan Centrale | 1 change | |
Regionale Veloce 4135+ 9996 | On time 19:37 Rome Ostiense | 3h38 | 23:15 Milan Centrale | 1 change | |
Regionale Veloce 4135+ 9962 | 19:37 Rome Ostiense | 4h43 | 0:20 Milan Centrale | 1 change | |
Regionale 12559+ 9962 | 19:53 Rome Ostiense | 4h27 | 0:20 Milan Centrale | 1 change | |
| Tuesday 5 May | |||||
![]() | 13:23 Rome Ostiense | 9h02 | 22:25 Milan Centrale | 0 changesdirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome Ostiense to Milan Centrale by train, coach or flight
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
05 May
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11 May
Why should you book Rome Ostiense to Milan Centrale trains with Omio?
Why book with Omio vs Frecciarossa?
- Compare with other providers: On Omio, you can not only buy tickets for Frecciarossa, but also compare tickets for the likes of Italo, Intercity Notte, Intercity or Regionale to find the best option for your trip from Rome Ostiense to Milan Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Frecciarossa with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Rome Ostiense to Milan Centrale.
Why book with Omio over Raileurope?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Rome Ostiense to Milan Centrale.
Journey information
Overview: Train from Rome Ostiense to Milan Centrale
Trains from Rome Ostiense to Milan Centrale run on average 29 times per day, taking around 5h 40m. Cheap train tickets for this journey start at £26 but you can travel from only £6 by coach.
There are 1 trains per day. The earliest train runs at 05:48, the last at 23:15. The fastest train covers the 481 km distance in 4h 13m.
Distance 481 km |
Average train duration 5h 40m |
Cheapest ticket price £26 |
Trains per day 29 |
Direct trains 1 |
Fastest train 4h 13m |
First train 5:48 |
Last train 23:15 |
Cheapest Month Feb |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Jul - Sept |
Busiest Day Sat |
Least Busy Day Fri |
Train companies: Frecciarossa, Italo, Intercity Notte, Intercity, Regionale from Rome Ostiense to Milan Centrale trainsFrecciarossa, Italo, Intercity Notte, Intercity, Regionale trains will get you between Rome Ostiense and Milan Centrale from £6. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Frecciarossa
Italo
Intercity Notte
Intercity
Regionale
FAQs: Rome Ostiense to Milan Centrale train
Find answers to the most common questions about traveling from Rome Ostiense to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Rome Ostiense and Milan Centrale
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available near the station with both short-term and long-term options.
- Ramen Bar Akira
- Eataly Roma
- Outside the main entrance.
- Elevators, ramps, restrooms.
- €1
- Hotel Abitart
- Hotel San Anselmo
- Hotel Villa San Pio
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-5 for regional and intercity trains
- Hall 2: platforms 6-11 for metropolitan services
- Metro: Line B
- Bus: Several lines available
- Tram: Line 3
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Rome Ostiense
More options for your journey from Rome Ostiense to Milan Centrale
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