The cheapest and fastest trains from Milan Centrale to Rome Ostiense
Cheapest price
£22
Average price
£22
Fastest journey
7 h 15 m
Average duration
7 h 15 m
Trains per day
1
Distance
481 km
The best way to find a cheap train ticket from Milan Centrale to Rome Ostiense is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Milan Centrale to Rome Ostiense will cost around £22 if you buy it on the day, but you can find cheap train tickets today for only £22.
Of the 1 trains that leave Milan Centrale for Rome Ostiense every day 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct trains cover the 481 km distance in an average of 7 h 15 m but if you time it right, some trains will get you there in just 7 h 15 m .
The slowest trains will take 7 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare train, coach and flight for Milan Centrale to Rome Ostiense
Omio recommends booking the train as it is the most popular option from Milan Centrale to Rome Ostiense among Omio's users. If you are prioritising price take the coach with prices starting from £6. For those with little time consider booking a flight which can get you there in 2h 10m. The ticket price range depends on the travel mode: a coach costs an average of £6, and a flight costs an average of £32.
Distance: 481 km
Compare train with
Most popular Train | Coach | Flight |
|---|---|---|
£38 Average Price | £10 Average Price Cheapest | £83 Average Price |
5h 21m Average total duration 4h 51m Onboard + 30m Additional time* | 8h 55m Average total duration 8h 25m Onboard + 30m Additional time* | 5h 10m Average total duration Fastest 2h 10m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Milan Centrale to Rome Ostiense train times
The table below shows live departures for Milan Centrale to Rome Ostiense trains for today, Friday 14 November. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
Regionale 2593 · ETRUSCHI LINE 4133 | 05:50 Milan Centrale | 10h46 | 16:36 Rome Ostiense | 1 change | |
FRECCIAROSSA 9607+ Regionale 12514 | 06:00 Milan Centrale | 3h52 | 09:52 Rome Ostiense | 1 change | |
9971+ Regionale 12516 | Delayed 06:16 06:15Milan Centrale | 4h07 | 10:22 Rome Ostiense | 1 change | |
9971+ Regionale 12520 | Delayed 06:16 06:15Milan Centrale | 4h40 | 10:55 Rome Ostiense | 1 change | |
9971+ Regionale 12514 | Delayed 06:16 06:15Milan Centrale | 3h37 | 09:52 Rome Ostiense | 1 change | |
FRECCIAROSSA 1000 9604+ Regionale 12516 | 06:30 Milan Centrale | 3h52 | 10:22 Rome Ostiense | 1 change | |
9917+ ETRUSCHI LINE 4132 | 06:40 Milan Centrale | 4h42 | 11:22 Rome Ostiense | 1 change | |
9917+ Regionale 12522 | 06:40 Milan Centrale | 5h12 | 11:52 Rome Ostiense | 1 change | |
9917+ Regionale 12520 | 06:40 Milan Centrale | 4h15 | 10:55 Rome Ostiense | 1 change | |
9941+ Regionale 12522 | 06:45 Milan Centrale | 5h07 | 11:52 Rome Ostiense | 1 change | |
9941+ Regionale 12520 | 06:45 Milan Centrale | 4h10 | 10:55 Rome Ostiense | 1 change | |
9941+ ETRUSCHI LINE 4132 | 06:45 Milan Centrale | 4h37 | 11:22 Rome Ostiense | 1 change | |
Intercity 657+ ETRUSCHI LINE 4133 | 07:05 Milan Centrale | 9h31 | 16:36 Rome Ostiense | 1 change | |
9998+ ETRUSCHI LINE 4132 | Delayed 07:17 07:15Milan Centrale | 4h07 | 11:22 Rome Ostiense | 1 change | |
9998+ Regionale 12522 | Delayed 07:17 07:15Milan Centrale | 4h37 | 11:52 Rome Ostiense | 1 change | |
9998+ Regionale 12520 | Delayed 07:17 07:15Milan Centrale | 3h40 | 10:55 Rome Ostiense | 1 change | |
FRECCIAROSSA 1000 9613 · FRECCIAROSSA 9466+ Regionale 20463 | 07:30 Milan Centrale | 3h44 | 11:14 Rome Ostiense | 2 changes | |
FRECCIAROSSA 1000 9613+ ETRUSCHI LINE 4132 | 07:30 Milan Centrale | 3h52 | 11:22 Rome Ostiense | 1 change | |
9919+ Regionale 12522 | On time 07:40 Milan Centrale | 4h12 | 11:52 Rome Ostiense | 1 change | |
9919+ Regionale 12524 | On time 07:40 Milan Centrale | 5h27 | 13:07 Rome Ostiense | 1 change | |
9919+ Regionale 4500 | On time 07:40 Milan Centrale | 4h42 | 12:22 Rome Ostiense | 1 change | |
FRECCIAROSSA 1000 9615+ Regionale 12522 | 07:58 Milan Centrale | 3h54 | 11:52 Rome Ostiense | 1 change | |
FRECCIAROSSA 9583+ Regionale 20352 | 08:10 Milan Centrale | 3h56 | 12:06 Rome Ostiense | 1 change | |
Intercity 659 · Intercity 511 | 08:10 Milan Centrale | 8h42 | 16:52 Rome Ostiense | 1 change | |
FRECCIAROSSA 1000 9617+ Regionale 4500 | 08:35 Milan Centrale | 3h47 | 12:22 Rome Ostiense | 1 change | |
9923+ ETRUSCHI LINE 4134 | 08:40 Milan Centrale | 4h42 | 13:22 Rome Ostiense | 1 change | |
9923+ Regionale 12524 | 08:40 Milan Centrale | 4h27 | 13:07 Rome Ostiense | 1 change | |
9923+ Regionale 12580 | 08:40 Milan Centrale | 4h57 | 13:37 Rome Ostiense | 1 change | |
FRECCIAROSSA 9527+ Regionale 20356 | 09:10 Milan Centrale | 3h56 | 13:06 Rome Ostiense | 1 change | |
9977+ Regionale 12524 | On time 09:15 Milan Centrale | 3h52 | 13:07 Rome Ostiense | 1 change | |
9977+ Regionale 12580 | On time 09:15 Milan Centrale | 4h22 | 13:37 Rome Ostiense | 1 change | |
9977+ ETRUSCHI LINE 4134 | On time 09:15 Milan Centrale | 4h07 | 13:22 Rome Ostiense | 1 change | |
9927+ Regionale 12572 | 09:40 Milan Centrale | 4h42 | 14:22 Rome Ostiense | 1 change | |
9927+ Regionale 12530 | 09:40 Milan Centrale | 5h27 | 15:07 Rome Ostiense | 1 change | |
9927+ Regionale 12564 | 09:40 Milan Centrale | 4h12 | 13:52 Rome Ostiense | 1 change | |
Intercity 597+ ETRUSCHI LINE 4137 | 09:50 Milan Centrale | 10h46 | 20:36 Rome Ostiense | 1 change | |
FRECCIAROSSA 1000 9623+ Regionale 12580 | 09:58 Milan Centrale | 3h39 | 13:37 Rome Ostiense | 1 change | |
FRECCIAROSSA 9587+ Regionale 20360 | 10:10 Milan Centrale | 3h56 | 14:06 Rome Ostiense | 1 change | |
9979+ Regionale 12572 | On time 10:15 Milan Centrale | 4h07 | 14:22 Rome Ostiense | 1 change | |
9979+ ETRUSCHI LINE 4136 | On time 10:15 Milan Centrale | 5h07 | 15:22 Rome Ostiense | 1 change | |
9979+ Regionale 12530 | On time 10:15 Milan Centrale | 4h52 | 15:07 Rome Ostiense | 1 change | |
FRECCIAROSSA 1000 9625+ Regionale 12572 | 10:25 Milan Centrale | 3h57 | 14:22 Rome Ostiense | 1 change | |
FRECCIAROSSA 8807 · FRECCIAROSSA 1000 9415+ Regionale 20497 | 10:35 Milan Centrale | 4h09 | 14:44 Rome Ostiense | 2 changes | |
9931+ ETRUSCHI LINE 4136 | 10:40 Milan Centrale | 4h42 | 15:22 Rome Ostiense | 1 change | |
9931+ Regionale 12530 | 10:40 Milan Centrale | 4h27 | 15:07 Rome Ostiense | 1 change | |
9931+ Regionale 12582 | 10:40 Milan Centrale | 4h57 | 15:37 Rome Ostiense | 1 change | |
FRECCIAROSSA 9535+ Regionale 20364 | 11:10 Milan Centrale | 3h56 | 15:06 Rome Ostiense | 1 change | |
Intercity 665+ Regionale 18399 · ETRUSCHI LINE 4137 | 11:10 Milan Centrale | 9h26 | 20:36 Rome Ostiense | 2 changes | |
9981+ ETRUSCHI LINE 4136 | On time 11:20 Milan Centrale | 4h02 | 15:22 Rome Ostiense | 1 change | |
9981+ Regionale 12530 | On time 11:20 Milan Centrale | 3h47 | 15:07 Rome Ostiense | 1 change | |
9981+ Regionale 12582 | On time 11:20 Milan Centrale | 4h17 | 15:37 Rome Ostiense | 1 change | |
9935+ Regionale 4502 | On time 11:40 Milan Centrale | 4h42 | 16:22 Rome Ostiense | 1 change | |
9935+ Regionale 12534 | On time 11:40 Milan Centrale | 4h27 | 16:07 Rome Ostiense | 1 change | |
9935+ Regionale 12538 | On time 11:40 Milan Centrale | 4h57 | 16:37 Rome Ostiense | 1 change | |
FRECCIAROSSA 1000 9631+ Regionale 12582 | 12:00 Milan Centrale | 3h37 | 15:37 Rome Ostiense | 1 change | |
9983+ Regionale 12538 | On time 12:20 Milan Centrale | 4h17 | 16:37 Rome Ostiense | 1 change | |
9983+ Regionale 12534 | On time 12:20 Milan Centrale | 3h47 | 16:07 Rome Ostiense | 1 change | |
9983+ Regionale 4502 | On time 12:20 Milan Centrale | 4h02 | 16:22 Rome Ostiense | 1 change | |
FRECCIAROSSA 9633+ Regionale 12534 | 12:30 Milan Centrale | 3h37 | 16:07 Rome Ostiense | 1 change | |
9939+ Regionale 12540 | 12:40 Milan Centrale | 4h12 | 16:52 Rome Ostiense | 1 change | |
9939+ ETRUSCHI LINE 4138 | 12:40 Milan Centrale | 4h45 | 17:25 Rome Ostiense | 1 change | |
9939+ Regionale 12584 | 12:40 Milan Centrale | 4h27 | 17:07 Rome Ostiense | 1 change | |
9985+ Regionale 12666 | 13:20 Milan Centrale | 4h32 | 17:52 Rome Ostiense | 1 change | |
9985+ ETRUSCHI LINE 4138 | 13:20 Milan Centrale | 4h05 | 17:25 Rome Ostiense | 1 change | |
9985+ Regionale 12584 | 13:20 Milan Centrale | 3h47 | 17:07 Rome Ostiense | 1 change | |
FRECCIAROSSA 1000 9641+ Regionale 12666 | 14:00 Milan Centrale | 3h52 | 17:52 Rome Ostiense | 1 change | |
Intercity 641+ InterCityNotte 795 | 14:10 Milan Centrale | 8h13 | 22:23 Rome Ostiense | 1 change | |
FRECCIAROSSA 1000 9643+ Regionale 12544 | 14:25 Milan Centrale | 3h42 | 18:07 Rome Ostiense | 1 change | |
FRECCIAROSSA 1000 9647+ ETRUSCHI LINE 4140 | 15:30 Milan Centrale | 3h52 | 19:22 Rome Ostiense | 1 change | |
9951+ Regionale 12552 | On time 15:40 Milan Centrale | 5h42 | 21:22 Rome Ostiense | 1 change | |
9951+ Regionale 12550 | On time 15:40 Milan Centrale | 4h12 | 19:52 Rome Ostiense | 1 change | |
9951+ Regionale 4506 | On time 15:40 Milan Centrale | 4h42 | 20:22 Rome Ostiense | 1 change | |
FRECCIAROSSA 1000 9649+ Regionale 12548 | 15:58 Milan Centrale | 3h39 | 19:37 Rome Ostiense | 1 change | |
9991+ Regionale 12552 | 16:15 Milan Centrale | 5h07 | 21:22 Rome Ostiense | 1 change | |
9991+ Regionale 12550 | 16:15 Milan Centrale | 3h37 | 19:52 Rome Ostiense | 1 change | |
9991+ Regionale 4506 | 16:15 Milan Centrale | 4h07 | 20:22 Rome Ostiense | 1 change | |
FRECCIAROSSA 1000 9651+ Regionale 4506 | 16:35 Milan Centrale | 3h47 | 20:22 Rome Ostiense | 1 change | |
9993+ Regionale 12554 | On time 16:45 Milan Centrale | 5h52 | 22:37 Rome Ostiense | 1 change | |
9993+ Regionale 12552 | On time 16:45 Milan Centrale | 4h37 | 21:22 Rome Ostiense | 1 change | |
FRECCIAROSSA 1000 9559+ Regionale 20388 | 17:10 Milan Centrale | 3h54 | 21:04 Rome Ostiense | 1 change | |
9995+ Regionale 12554 | On time 17:20 Milan Centrale | 5h17 | 22:37 Rome Ostiense | 1 change | |
9995+ Regionale 12552 | On time 17:20 Milan Centrale | 4h02 | 21:22 Rome Ostiense | 1 change | |
FRECCIAROSSA 9657+ Regionale 12552 | 17:30 Milan Centrale | 3h52 | 21:22 Rome Ostiense | 1 change | |
9959+ Regionale 12554 | On time 17:40 Milan Centrale | 4h57 | 22:37 Rome Ostiense | 1 change | |
9997+ Regionale 12554 | 17:45 Milan Centrale | 4h52 | 22:37 Rome Ostiense | 1 change | |
Intercity 687+ InterCityNotte 799 | 20:10 Milan Centrale | 9h07 | 05:17 Rome Ostiense | 1 change | |
Regionale TTPER 2483+ InterCityNotte 797+ Regionale 12840 | 20:20 Milan Centrale | 9h17 | 05:37 Rome Ostiense | 2 changes | |
InterCityNotte 755+ Regionale Veloce 4151 · Regionale 20405 | 20:50 Milan Centrale | 9h54 | 06:44 Rome Ostiense | 2 changes | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan Centrale to Rome Ostiense by train, coach or flight
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Milan Centrale to Rome Ostiense
Trains from Milan Centrale to Rome Ostiense run on average 30 times per day, taking around 4h 51m. Cheap train tickets for this journey start at £17 but you can travel from only £6 by coach.
There are 1 trains per day. The earliest train runs at 03:45, the last at 20:05. The fastest train covers the 481 km distance in 7h 15m.
Distance 481 km |
Average train duration 4h 51m |
Cheapest ticket price £17 |
Trains per day 30 |
Direct trains 1 |
Fastest train 7h 15m |
First train 03:45 |
Last train 20:05 |
Train companies: Italo, Frecciarossa, Intercity Notte from Milan Centrale to Rome Ostiense trainsItalo, Frecciarossa, Intercity Notte trains will get you between Milan Centrale and Rome Ostiense from £6. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Frecciarossa
Intercity Notte
FAQs: Milan Centrale to Rome Ostiense train
Find answers to the most common questions about traveling from Milan Centrale to Rome Ostiense by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Rome Ostiense, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Milan Centrale and Rome Ostiense
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available near the station with both short-term and long-term options.
- Ramen Bar Akira
- Eataly Roma
- Outside the main entrance.
- Elevators, ramps, restrooms.
- €1
- Hotel Abitart
- Hotel San Anselmo
- Hotel Villa San Pio
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-5 for regional and intercity trains
- Hall 2: platforms 6-11 for metropolitan services
- Metro: Line B
- Bus: Several lines available
- Tram: Line 3
More options for your journey from Milan Centrale to Rome Ostiense
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