The cheapest and fastest trains from Madrid to Palermo
Cheapest price
£367
Average price
£367
Fastest journey
2 d 22 h 3 m
Average duration
2 d 22 h 3 m
Trains per day
1
Distance
1489 km
The best way to find a cheap train ticket from Madrid to Palermo is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Madrid to Palermo will cost around £367 if you buy it on the day, but you can find cheap train tickets today for only £367.
To travel from Madrid to Palermo you need to make at least 4 changes.


Travel Information
Compare train, coach and flight for Madrid to Palermo
Omio recommends booking the flight as it is the most popular option from Madrid to Palermo among Omio's users. If you are prioritising price take the flight with prices starting from £20. For those with little time consider booking a flight which can get you there in 3h 12m. In case you are seeking to minimise your carbon footprint the coach is your best bet as it emits only 1.5 - 3.7kg. The ticket price range depends on the travel mode: a flight costs an average of £20, and a train costs an average of £377.
Distance: 1489 km
Compare train with
| Train | Most popular Flight | Coach |
|---|---|---|
£388 Average Price | £126 Average Price Cheapest | £183 Average Price |
60h 52m Average total duration 60h 22m Onboard + 30m Additional time* | 6h 12m Average total duration Fastest 3h 12m Onboard + 3h 0m Additional time* | 51h 31m Average total duration 51h 1m Onboard + 30m Additional time* |
- CO2 emissions | 4.5 - 8.9kg CO2 emissions | 1.5 - 3.7kg CO2 emissions Lowest |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Madrid to Palermo train times
The table below shows live departures for Madrid to Palermo trains for today, Thursday 5 March. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
![]() | 21:07 Madrid | 70h03 | 19:10 Palermo | 4 changes | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Madrid to Palermo by train, coach or flight
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
05 Mar
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Why should you book Madrid to Palermo trains with Omio?
Why book with Omio vs iryo?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare iryo with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Madrid to Palermo.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Madrid to Palermo.
Journey information
Overview: Train from Madrid to Palermo
Trains from Madrid to Palermo run on average 2 times per day, taking around 60h 22m. Cheap train tickets for this journey start at £377 but you can travel from only £20 by flight.
The earliest train runs at 06:40, the last at 06:40. The fastest train covers the 1489 km distance in 60h 22m.
Distance 1489 km |
Average train duration 60h 22m |
Cheapest ticket price £377 |
Trains per day 2 |
Fastest train 60h 22m |
First train 06:40 |
Last train 06:40 |
Train companies: iryo from Madrid to Palermo trainsiryo trains will get you between Madrid and Palermo from £20. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
iryo
FAQs: Madrid to Palermo train
Find answers to the most common questions about traveling from Madrid to Palermo by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

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