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The cheapest and fastest trains from Karlovy Vary to Frankfurt am Main
Showing times and prices for 28 Feb
Cheapest price
£29
Average price
£96
Fastest journey
6 h 10 m
Average duration
6 h 24 m
Trains per day
29
Distance
298 km
Cheap tickets
The best way to find a cheap train ticket from Karlovy Vary to Frankfurt am Main is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Karlovy Vary to Frankfurt am Main will cost around £96 if you buy it on the day, but you can find cheap train tickets today for only £29.
Fast trains
To travel from Karlovy Vary to Frankfurt am Main you need to make at least 3 changes.
Sp 1665 · Sp 5284 · OPB 79727 · R 346810:226h40
Karlovy Vary, nádraží17:02Frankfurt (Main) Hbf
£291One-way
4 changes
IC 503 · Sp 5280 · R 3460 · ICE 72205:507h12
Karlovy Vary, nádraží13:02Frankfurt (Main) Hbf
£291One-way
3 changes
Os 7000 · Sp 5282 · R 3437 · R 464607:357h11
Karlovy Vary, nádraží14:46Frankfurt South station
£411One-way
3 changes
R 611 · rj 176 · ICE 155410:579h40
Karlovy Vary, nádraží20:37Frankfurt (Main) Hbf
£591One-way
2 changes
R 614+
20879+3474 · ICE 2413:036h34
Karlovy Vary, nádraží19:37Frankfurt (Main) Hbf
£841One-way
3 changes
Os 7300+20891+3824 · Bus EV05:276h10
Karlovy Vary, nádraží11:37Frankfurt (Main) Hbf
£1021One-way
4 changes
Os 7300 · Os 20891 · R 4857 · R 345805:276h10
Karlovy Vary, nádraží11:37Frankfurt (Main) Hbf
£1361One-way
4 changes
Os 7300+20891+3824 · Bus EV05:276h32
Karlovy Vary, nádraží11:59Frankfurt am Main Flughafen
£1041One-way
5 changes
R 614+20879+3474 · ICE 2413:036h34
Karlovy Vary, nádraží19:37Frankfurt (Main) Hbf
£841One-way
3 changes
R 618+20875+3466 · ICE 2809:036h34
Karlovy Vary, nádraží15:37Frankfurt (Main) Hbf
£941One-way
3 changes
Travel Information
Compare coach, train and flight for Karlovy Vary to Frankfurt am Main
Omio recommends booking the train as it is the most popular option from Karlovy Vary to Frankfurt am Main among Omio's users. If you are prioritising price take the train with prices starting from £21. For those with little time consider booking a train which can get you there in 5h 19m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a train costs an average of £21, and a flight costs an average of £78.
Distance: 298 km
Compare train with
Most popular Train | Coach | Flight |
|---|---|---|
£30 Average Price Cheapest | £35 Average Price | £116 Average Price |
5h 49m Average total duration Fastest 5h 19m Onboard + 30m Additional time* | 8h 34m Average total duration 8h 4m Onboard + 30m Additional time* | 12h 18m Average total duration 9h 18m Onboard + 3h 0m Additional time* |
0.1 - 0.3kg CO2 emissions Lowest | 0.3 - 0.7kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Karlovy Vary to Frankfurt am Main train times
The table below shows live departures for Karlovy Vary to Frankfurt am Main trains for tomorrow, Saturday 28 February. You can also manually refresh the results below to see updated train journeys.
Last updated at 22:27
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
| Os 7300+20891+3824 · Bus EV | On time 04:27 Karlovy Vary, nádraží | 6h10 | 10:37 Frankfurt (Main) Hbf | 4 changes | |
| Os 7300+20891+3824 · Bus EV | On time 04:27 Karlovy Vary, nádraží | 6h52 | 11:19 Frankfurt Airport long-distance station | 4 changes | |
| Os 7300+20891+3824 · Bus EV | 04:27 Karlovy Vary, nádraží | 6h32 | 10:59 Frankfurt am Main Flughafen | 5 changes | |
| Os 7300 · Os 20891 · R 4857 · R 3458 | On time 04:27 Karlovy Vary, nádraží | 6h10 | 10:37 Frankfurt (Main) Hbf | 4 changes | |
| IC 503 · 5280 · Bus EV · ICE 722 | On time 04:50 Karlovy Vary, nádraží | 7h12 | 12:02 Frankfurt (Main) Hbf | 3 changes | |
| IC 503 · 5280 · Bus EV · ICE 722 | On time 04:50 Karlovy Vary, nádraží | 7h29 | 12:19 Frankfurt Airport long-distance station | 3 changes | |
| IC 503 · Sp 5280 · R 3460 · ICE 722 | On time 04:50 Karlovy Vary, nádraží | 7h12 | 12:02 Frankfurt (Main) Hbf | 3 changes | |
| Os 19802 · 21980 · 74011 · 3658 | On time 05:10 Karlovy Vary, nádraží | 8h49 | 13:59 Frankfurt am Main Flughafen | 5 changes | |
| Os 19802 · 21980 · 74011 · 3658 | On time 05:10 Karlovy Vary, nádraží | 8h27 | 13:37 Frankfurt (Main) Hbf | 4 changes | |
| R 607 · rj 178 · ICE 1558 | On time 05:57 Karlovy Vary, nádraží | 9h40 | 15:37 Frankfurt (Main) Hbf | 2 changes | |
| Os 7000 · Sp 5282 · R 3437 · R 4646 | 06:35 Karlovy Vary, nádraží | 7h11 | 13:46 Frankfurt South station | 3 changes | |
| Os 7000 · 5282 · 3437 · 4646 | 06:35 Karlovy Vary, nádraží | 7h22 | 13:57 Frankfurt (Main) Hbf | 3 changes | |
| Os 7000 · 5282 · Bus EV · ICE 628 | On time 06:35 Karlovy Vary, nádraží | 7h44 | 14:19 Frankfurt Airport long-distance station | 3 changes | |
| R 609 · rj 382 · ICE 1556 | On time 07:57 Karlovy Vary, nádraží | 9h40 | 17:37 Frankfurt (Main) Hbf | 2 changes | |
| R 618+20875+3466 · ICE 28 | On time 08:03 Karlovy Vary, nádraží | 6h34 | 14:37 Frankfurt (Main) Hbf | 3 changes | |
| R 618 · Os 20875 · R 3466 · ICE 28 | On time 08:03 Karlovy Vary, nádraží | 6h34 | 14:37 Frankfurt (Main) Hbf | 3 changes | |
| R 618+20875+3466 · ICE 28 | 08:03 Karlovy Vary, nádraží | 6h56 | 14:59 Frankfurt am Main Flughafen | 4 changes | |
| R 618+20875+3466 · ICE 626 | On time 08:03 Karlovy Vary, nádraží | 7h16 | 15:19 Frankfurt Airport long-distance station | 3 changes | |
| Sp 1665 · Sp 5284 · OPB 79727 · R 3468 | On time 09:22 Karlovy Vary, nádraží | 6h40 | 16:02 Frankfurt (Main) Hbf | 4 changes | |
| Sp 1665 · 5284 · Bus EV · ICE 624 | On time 09:22 Karlovy Vary, nádraží | 6h57 | 16:19 Frankfurt Airport long-distance station | 3 changes | |
| Sp 1665 · 5284 · Bus EV · ICE 624 | On time 09:22 Karlovy Vary, nádraží | 6h40 | 16:02 Frankfurt (Main) Hbf | 3 changes | |
| R 611 · rj 176 · ICE 1554 | On time 09:57 Karlovy Vary, nádraží | 9h40 | 19:37 Frankfurt (Main) Hbf | 2 changes | |
| R 616+20877+3470 · ICE 1224 | 10:03 Karlovy Vary, nádraží | 6h56 | 16:59 Frankfurt am Main Flughafen | 4 changes | |
| R 616+20877+3470 · ICE 1224 | On time 10:03 Karlovy Vary, nádraží | 6h34 | 16:37 Frankfurt (Main) Hbf | 3 changes | |
| R 616 · Os 20877 · R 3470 · ICE 1224 | On time 10:03 Karlovy Vary, nádraží | 6h34 | 16:37 Frankfurt (Main) Hbf | 3 changes | |
| R 616+20877+3470 · ICE 622 | On time 10:03 Karlovy Vary, nádraží | 7h16 | 17:19 Frankfurt Airport long-distance station | 3 changes | |
| Sp 1667 · 5286 · Bus EV · ICE 620 | On time 11:22 Karlovy Vary, nádraží | 6h40 | 18:02 Frankfurt (Main) Hbf | 3 changes | |
| Sp 1667 · 5286 · Bus EV · ICE 620 | On time 11:22 Karlovy Vary, nádraží | 6h57 | 18:19 Frankfurt Airport long-distance station | 3 changes | |
| R 614+20879+3474 · ICE 24 | On time 12:03 Karlovy Vary, nádraží | 6h34 | 18:37 Frankfurt (Main) Hbf | 3 changes | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Karlovy Vary to Frankfurt am Main by coach, train or flight
Compare coach, train and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sat
28 Feb
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01 Mar
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Mon
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Tue
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03 Mar
Wed
04 Mar
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Thu
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Fri
06 Mar
06 Mar
Why should you book Karlovy Vary to Frankfurt am Main trains with Omio?
Deutsche Bahn as well as České dráhy offer trains services from Karlovy Vary to Frankfurt am Main.
Omio is an official ticket reseller for all your travel options from Karlovy Vary to Frankfurt am Main.
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of České dráhy to find the best option for your trip from Karlovy Vary to Frankfurt am Main.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Karlovy Vary to Frankfurt am Main.
Why book with Omio over Trainline, Wanderu or Raileurope?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Karlovy Vary to Frankfurt am Main.
Journey information
Overview: Train from Karlovy Vary to Frankfurt am Main
Czechia
Germany
Trains from Karlovy Vary to Frankfurt am Main run on average 14 times per day, taking around 5h 19m. Cheap train tickets for this journey start at £21 but you can travel from only £20 by coach.
The earliest train runs at 00:04, the last at 23:54. The fastest train covers the 298 km distance in 5h 11m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Coach from £20
Distance 298 km |
Average train duration 5h 19m |
Cheapest ticket price £21 |
Trains per day 14 |
Fastest train 5h 11m |
First train 00:04 |
Last train 23:54 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Coach from £20
Train companies: Deutsche Bahn, České dráhy from Karlovy Vary to Frankfurt am Main trainsDeutsche Bahn, České dráhy trains will get you between Karlovy Vary and Frankfurt am Main from £20. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
About
Deutsche Bahn (DB) is Germany’s main train operator, running around 40,000 domestic and international services each day. Its fleet includes a variety of train types: high-speed ICE (Intercity Express) trains, reaching up to 300 km/h; IC (Intercity) and EC (EuroCity) trains for long-distance travel; and IRE (Interregio-Express), RE (Regional Express), and RB (Regionalbahn) services for regional and local connections. While bathrooms are standard on all trains, amenities such as onboard restaurants and free Wi-Fi are available only on certain train types and routes. DB offers a wide range of fares, including Super Saver, Saver, and Flexible tickets, along with discount cards like the BahnCard 25, 50, and 100. Additional options include single tickets, day tickets, and group tickets. Popular routes include Berlin–Munich, Hamburg–Frankfurt, Cologne–Stuttgart, Berlin–Dresden, and Hamburg–Cologne, as well as numerous regional services across Germany.
Luggage & cancellation policy
Average Duration
5h 11m
Cheapest Price
£21
Luggage included
Passengers are allowed to bring hand luggage and one additional larger item free of charge, provided they can carry it themselves
Luggage storage
Luggage can be stored in overhead racks, under the seat, or in designated luggage areas near the doors or in the middle of the carriage.
Cancellation Policy
Tickets can be canceled based on their fare conditions as mentioned in what type of train tickets are refundable?
Refund
If DB cancels a train, passengers are entitled to a full refund of the ticket price.
Amenities on board the train
Wifi
Food sold onboard
Most ICE and many IC/EC trains have:
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Seat reservation
Second Class:
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Toilets
USB plugs
Accessibility
DB trains are equipped with facilities for passengers with reduced mobility, including wheelchair spaces, accessible restrooms, and assistance services.
Pets
Small pets (e.g. cats, small dogs, etc.):
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Quiet zone
České dráhy
About
Czech Railways (České dráhy, ČD) is the largest railway company in the Czech Republic, connecting major cities, small towns, and even international destinations across Europe. Its extensive fleet of modern trains ranges from comfortable regional services with A/C and onboard WiFi to high-speed trains offering dining cars, power outlets, and premium seating for long-distance journeys. Czech Railways combines affordability and convenience, making it a popular choice for travelers exploring the Czech Republic and beyond.
Luggage & cancellation policy
Average Duration
6h 33m
Cheapest Price
£25
České dráhy frequency
12 a day
Luggage included
You can transport briefcases, laptops, rucksacks, trolley bags and suitcases on board at no charge.
Additional luggage
Items of luggage must not be so big or heavy that they cannot be carried by a single person, with a generous maximum size of 90 x 60 x 40 cm and a maximum weight of 50kg.
Luggage storage
Luggage can be stored above or below the seat, on the passenger's lap, or in special luggage racks in certain carriages.
Cancellation Policy
Tickets purchased online can be returned free of charge up to 15 minutes before the train's departure.
Refund
If a train is completely canceled, booking fees are refundable, and compensation may be due directly from the rail operator.
Pregnant on board
Being pregnant on board is allowed.
Unaccompagned minor
Automatic compensation for online ČD domestic tickets applies if the system registers a delay of more than 60 minutes at the destination and the ticket was checked by the conductor.
Amenities on board the train
Food sold onboard
A hearty breakfast is included in the ticket price for sleeper carriage services.
Seat reservation
Seat reservations are included with tickets and adjacent seats are booked wherever possible.
Accessibility
Czech Railways is continuously expanding its fleet of wheelchair-accessible carriages and offers assistance for passengers with limited mobility.
Pets
Small pets are allowed on board, but cannot be transported in 1st class, restaurant, or bistro cars.
FAQs: Karlovy Vary to Frankfurt am Main train
Find answers to the most common questions about traveling from Karlovy Vary to Frankfurt am Main by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Frankfurt am Main, this guide helps you travel smarter and with confidence.
The cost of a train ticket from Karlovy Vary to Frankfurt am Main can vary. The cheapest tickets are usually available from £21, while the average price tends to be around £30.
The train journey from Karlovy Vary to Frankfurt am Main covers a distance of 298 km and takes approximately 5h 11m. Trains run 14 per day.
The train distance from Karlovy Vary to Frankfurt am Main is 298 km.
The first train from Karlovy Vary to Frankfurt am Main leaves at 0:04.
The last train from Karlovy Vary to Frankfurt am Main departs at 23:54.
Trains from Karlovy Vary to Frankfurt am Main run approximately 14 times per day.
Unfortunately, there is no direct train service currently available from Karlovy Vary to Frankfurt am Main.
To get from Karlovy Vary to Frankfurt am Main, you can choose from several travel options including coach, train and flight.
There is no night train service from Karlovy Vary to Frankfurt am Main.
The train station in Karlovy Vary that goes to Frankfurt am Main is Karlovy Vary, nádraží, and it arrives at Frankfurt (Main) Hbf.
The cheapest way to get from Karlovy Vary to Frankfurt am Main is by coach, costing approximately £20.
Booking trains from Karlovy Vary to Frankfurt am Main in advance is advisable, especially during peak travel seasons or for long journeys, to ensure availability and secure better fares.
The train journey from Karlovy Vary to Frankfurt am Main offers scenic views, including picturesque countryside landscapes, charming villages, and stretches along the River Main, providing a pleasant and visually appealing travel experience.
A day trip from Karlovy Vary to Frankfurt am Main is not feasible as the journey takes 5h 11m. Trains operate 13 times per day over a distance of 298 km.
In Frankfurt am Main, you can ascend the Main Tower for panoramic city views, explore the vibrant Kleinmarkthalle for diverse culinary delights, and visit the Senckenberg Natural History Museum, renowned for its dinosaur fossils. Stroll along the River Main for scenic vistas, and enjoy the bustling atmosphere of the Zeil, the city's premier shopping street. Key sights include the historic Römer city hall, the Städel Museum with its extensive art collection, the Palmengarten botanical garden, the Goethe House museum, and the impressive Frankfurt Cathedral.
To explore the key attractions and get a sense of the city, you typically need about 2 to 3 days in Frankfurt am Main.
Yes, you can take the train from Karlovy Vary to Frankfurt am Main.
popular train stations
Important Stations and Airports in Karlovy Vary and Frankfurt am Main
Karlovy Vary
Frankfurt am Main
The major train station for departures in Karlovy Vary is Karlovy Vary nádraží. Find all the information you need to know about services, amenities and connections at Karlovy Vary nádraží for your trip from Karlovy Vary to Frankfurt am Main.
Amenities at train station
Parking
Dining
ATM
Taxis
Accessibility
WC
Hotel
Bike Parking
Karlovy Vary-Dvory nádraží
Amenities at train station
ParkingDiningAccessibilityHotelBike Parkinginformation
Distance to city center
2 km
Number of platforms
2Accessibility
- Ramps.
Public transport options for Karlovy Vary-Dvory nádraží
- Bus: Local bus services available
Karlovy Vary, dolní nádraží
Amenities at train station
ParkingDiningATMTaxisAccessibilityWCHotelBike ParkingThe major train station for arrivals in Frankfurt am Main is Frankfurt (Main) Hbf. Find all the information you need to know about services, amenities and connections at Frankfurt (Main) Hbf for your journey to Frankfurt am Main from Karlovy Vary.
Amenities at train station
Wifi
Lockers
ShoppingParkingDiningATMTaxisAccessibilityWCHotel
Lounge
Lost and Found Office
Ticket OfficeBike Parking
Bike Rental
Car Rental
Information Deskinformation
Ticket Office Hours
- Mon - Fri: 07:00 - 21:00
- Sat - Sun: 09:00 - 21:00
Distance to city center
1 kmWifi
- Free Wi-Fi in the station.
Lockers
- Luggage lockers are located in the main hall.
Dining
- asiagourmet
- Burger King
- Ciao Bella
- Coffee Fellows
- Crepes de France Express
- dean&david
- Starbucks
- Uddin's Sky Sportsbar
- McDonald's
- Dunkin Donuts
- & many more
Accessibility
- Step-free access and step markings. Contact the Mobility Service Centre at +49 3065212888 or [email protected].
Hotel
- Hotel Cristall
- Grand Hotel Empire
- Hotel Carlton
Information Desk
- Located opposite Platforms 12 and 13.
Frankfurt Flughafen Fernbf
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelShowerLoungeLost and Found OfficeTicket OfficeBike ParkingCar RentalInformation DeskLuggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 10:00 PM Monday - Sunday
Distance to city center
10 kmNumber of platforms
4Wifi
- Free
Parking
- The car park is open 24/7, accessible via Terminal 1 and Terminal 2 parking areas.
Dining
- Restaurant Käfer's
- McDonald's
- Asia Snack Box
Taxis
- Outside the main entrance.
Accessibility
- Elevators, ramps.
WC
- €1
Hotel
- Sheraton Frankfurt Airport Hotel
- Hilton Frankfurt Airport
- Hilton Garden Inn Frankfurt Airport
Shower
- Cost €6
Lounge
- Located in the main hall
Lost and Found Office
- Located in the main hall
Car Rental
- Avis
- Europcar
- Hertz
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, platform 1-4 for long-distance and regional trains
- Hall 2: connection to Terminal 1 of the airport
- Hall 3: connection to Terminal 2 of the airport
Public transport options for Frankfurt Flughafen Fernbf
- S-Bahn: Lines S8, S9
- Bus: Several lines available
- Long-distance buses: Available at the airport
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelLoungeLost and Found OfficeTicket OfficeBike ParkingCar RentalInformation DeskLuggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 10:00 PM Monday - Sunday
Distance to city center
10 kmNumber of platforms
3Wifi
- Free
Parking
- The car park is open 24/7. Access via Terminal 1 and Terminal 2.
Dining
- Restaurant Käfer's
- McDonald's
- Asia Snack Box
Taxis
- Outside the main entrance.
Accessibility
- Elevators, ramps, restrooms.
WC
- €1
Hotel
- Sheraton Frankfurt Airport Hotel
- Hilton Frankfurt Airport
- Steigenberger Airport Hotel
Lounge
- Located in the main hall
Lost and Found Office
- Located in the main hall
Car Rental
- Avis
- Europcar
- Hertz
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, platforms 1-3 for regional and S-Bahn trains
- Hall 2: access to airport terminals
Public transport options for Frankfurt (M) Flughafen Regionalbf
- S-Bahn: Lines S8, S9
- Regional trains: RE2, RE3, RE59
- Bus: Several lines available
More options for your journey from Karlovy Vary to Frankfurt am Main
Here are some other resources that might have the information you need
Most popular trains to and from Frankfurt am Main and Karlovy Vary
Most popular train connections to Frankfurt am Main
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