The cheapest and fastest trains from Domodossola to Rome
Cheapest price
£63
Average price
£99
Fastest journey
5 h 55 m
Average duration
6 h 3 m
Trains per day
64
Distance
577 km
The best way to find a cheap train ticket from Domodossola to Rome is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Domodossola to Rome will cost around £99 if you buy it on the day, but you can find cheap train tickets today for only £63.
To travel from Domodossola to Rome you need to make at least one change.
Regionale 11439+
InterCityNotte 79718:4811h32Domodossola station6:20Rome Ostiense£631One-way1 change
Autobus TRENORD 4217A · Regionale 10217+
81436:3311h46Domodossola station18:19Rome Termini£971One-way2 changes
Autobus TRENORD 4225A · Regionale 10215+
99395:1512h04Domodossola station17:19Rome Termini£971One-way2 changes
Autobus TRENORD 4437A · Regionale TRENORD 2437+
996317:037h21Domodossola station0:24Rome Termini£971One-way2 changes
Autobus TRENORD 4235A · Regionale 10235+
996315:219h03Domodossola station0:24Rome Termini£971One-way2 changes
Autobus EC065+
999515:305h55Domodossola station21:25Rome Termini£1021One-way1 change
Autobus EC041+
99798:306h00Domodossola station14:30Rome Termini£1021One-way1 change
Autobus TRENORD 2427A · Regionale TRENORD 2427+
FRECCIAROSSA 964112:106h05Domodossola station18:15Rome Termini£1031One-way2 changes
Autobus TRENORD 4419A · Regionale TRENORD 2419+
FRECCIAROSSA 96238:036h07Domodossola station14:10Rome Termini£1031One-way2 changes
Autobus TRENORD 4435A · Regionale TRENORD 2435+
FRECCIAROSSA 966116:036h07Domodossola station22:10Rome Termini£1031One-way2 changes
Travel Information
Compare train, flight and coach for Domodossola to Rome
Omio recommends booking the train as it is the most popular option from Domodossola to Rome among Omio's users. If you are prioritising price take the train with prices starting from £24. For those with little time consider booking a flight which can get you there in 1h 13m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a train costs an average of £24, and a flight costs an average of £42.
Distance: 577 km
Compare train with
Most popular Train | Flight | Coach |
|---|---|---|
£53 Average Price Cheapest | £85 Average Price | £56 Average Price |
7h 9m Average total duration 6h 39m Onboard + 30m Additional time* | 4h 13m Average total duration Fastest 1h 13m Onboard + 3h 0m Additional time* | 15h 45m Average total duration 15h 15m Onboard + 30m Additional time* |
0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.5kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Domodossola to Rome train times
The table below shows live departures for Domodossola to Rome trains for tomorrow, Friday 19 June. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
Autobus TRENORD 4411A · Regionale TRENORD 2411+ FRECCIAROSSA 9607 | 4:03 Domodossola station | 6h08 | 10:11 Rome Termini | 2 changes | |
Autobus TRENORD 4411A · Regionale TRENORD 2411+ 9971 | On time 4:03 Domodossola station | 6h22 | 10:25 Rome Termini | 2 changes | |
Autobus TRENORD 4411A · Regionale TRENORD 2411+ 9941 | On time 4:03 Domodossola station | 6h57 | 11:00 Rome Termini | 2 changes | |
Autobus TRENORD 4411A · Regionale TRENORD 2411+ 9917 | On time 4:03 Domodossola station | 7h16 | 11:19 Rome Termini | 2 changes | |
Autobus TRENORD 4413A · Regionale TRENORD 2413+ 9998 | On time 5:03 Domodossola station | 6h22 | 11:25 Rome Termini | 2 changes | |
Autobus TRENORD 4413A · Regionale TRENORD 2413+ 9975 | 5:03 Domodossola station | 7h22 | 12:25 Rome Termini | 2 changes | |
Autobus TRENORD 4413A · Regionale TRENORD 2413+ FRECCIAROSSA 9611 | 5:03 Domodossola station | 6h07 | 11:10 Rome Termini | 2 changes | |
Autobus TRENORD 4413A · Regionale TRENORD 2413+ 9919 | On time 5:03 Domodossola station | 7h16 | 12:19 Rome Termini | 2 changes | |
Autobus TRENORD 4225A · Regionale 10215+ 9939 | On time 5:15 Domodossola station | 12h04 | 17:19 Rome Termini | 2 changes | |
Autobus TRENORD 4225A · Regionale 10215+ 8143 | 5:15 Domodossola station | 13h04 | 18:19 Rome Termini | 2 changes | |
Regionale 11413 · Regionale Veloce 2053+ 9939 | On time 5:20 Domodossola station | 11h59 | 17:19 Rome Termini | 2 changes | |
Autobus TRENORD 4415A · Regionale TRENORD 2415+ 9975 | 5:53 Domodossola station | 6h32 | 12:25 Rome Termini | 2 changes | |
Autobus TRENORD 4415A · Regionale TRENORD 2415+ FRECCIAROSSA 9615 | 5:53 Domodossola station | 6h22 | 12:15 Rome Termini | 2 changes | |
Autobus TRENORD 4415A · Regionale TRENORD 2415+ 9977 | On time 5:53 Domodossola station | 7h32 | 13:25 Rome Termini | 2 changes | |
Autobus TRENORD 4415A · Regionale TRENORD 2415+ 9923 | 5:53 Domodossola station | 7h31 | 13:24 Rome Termini | 2 changes | |
Regionale 11415 · Regionale Veloce 2015+ 9975 | 6:17 Domodossola station | 6h08 | 12:25 Rome Termini | 2 changes | |
Regionale 11415 · Regionale Veloce 2015+ FRECCIAROSSA 9617 | 6:17 Domodossola station | 6h22 | 12:39 Rome Termini | 2 changes | |
Regionale 11415 · Regionale Veloce 2015+ 9977 | On time 6:17 Domodossola station | 7h08 | 13:25 Rome Termini | 2 changes | |
Regionale 11415 · Regionale Veloce 2015+ 9923 | 6:17 Domodossola station | 7h07 | 13:24 Rome Termini | 2 changes | |
Autobus TRENORD 4217A · Regionale 10217+ 8143 | 6:33 Domodossola station | 11h46 | 18:19 Rome Termini | 2 changes | |
Autobus TRENORD 4217A · Regionale 10217+ 9939 | On time 6:33 Domodossola station | 10h46 | 17:19 Rome Termini | 2 changes | |
Autobus TRENORD 4417A · Regionale TRENORD 2417+ 9979 | On time 7:03 Domodossola station | 7h27 | 14:30 Rome Termini | 2 changes | |
Autobus TRENORD 4417A · Regionale TRENORD 2417+ 9977 | On time 7:03 Domodossola station | 6h22 | 13:25 Rome Termini | 2 changes | |
Autobus TRENORD 4417A · Regionale TRENORD 2417+ FRECCIAROSSA 9619 | 7:03 Domodossola station | 6h07 | 13:10 Rome Termini | 2 changes | |
Autobus TRENORD 4417A · Regionale TRENORD 2417+ 9931 | 7:03 Domodossola station | 8h16 | 15:19 Rome Termini | 2 changes | |
Autobus TRENORD 4419A · Regionale TRENORD 2419+ FRECCIAROSSA 9623 | 8:03 Domodossola station | 6h07 | 14:10 Rome Termini | 2 changes | |
Autobus TRENORD 4419A · Regionale TRENORD 2419+ 9981 | On time 8:03 Domodossola station | 7h22 | 15:25 Rome Termini | 2 changes | |
Autobus TRENORD 4419A · Regionale TRENORD 2419+ 9979 | On time 8:03 Domodossola station | 6h27 | 14:30 Rome Termini | 2 changes | |
Autobus TRENORD 4419A · Regionale TRENORD 2419+ 9931 | 8:03 Domodossola station | 7h16 | 15:19 Rome Termini | 2 changes | |
Autobus EC041+ 9979 | On time 8:30 Domodossola station | 6h00 | 14:30 Rome Termini | 1 change | |
Autobus EC041+ 9981 | On time 8:30 Domodossola station | 6h55 | 15:25 Rome Termini | 1 change | |
Autobus EC041+ 9931 | 8:30 Domodossola station | 6h49 | 15:19 Rome Termini | 1 change | |
Autobus TRENORD 2427A · Regionale TRENORD 2427+ FRECCIAROSSA 9641 | 12:10 Domodossola station | 6h05 | 18:15 Rome Termini | 2 changes | |
Autobus TRENORD 2427A · Regionale TRENORD 2427+ 9987 | On time 12:10 Domodossola station | 6h15 | 18:25 Rome Termini | 2 changes | |
Autobus TRENORD 2427A · Regionale TRENORD 2427+ 9947 | 12:10 Domodossola station | 7h09 | 19:19 Rome Termini | 2 changes | |
Autobus TRENORD 2427A · Regionale TRENORD 2427+ 9989 | On time 12:10 Domodossola station | 7h15 | 19:25 Rome Termini | 2 changes | |
Regionale 11427 · Regionale Veloce 2029+ FRECCIAROSSA 9645 | 12:45 Domodossola station | 6h30 | 19:15 Rome Termini | 2 changes | |
Regionale 11427 · Regionale Veloce 2029+ 9989 | On time 12:45 Domodossola station | 6h40 | 19:25 Rome Termini | 2 changes | |
Regionale 11427 · Regionale Veloce 2029+ 9951 | On time 12:45 Domodossola station | 7h34 | 20:19 Rome Termini | 2 changes | |
Regionale 11427 · Regionale Veloce 2029+ 9991 | 12:45 Domodossola station | 7h40 | 20:25 Rome Termini | 2 changes | |
Autobus TRENORD 4431A · Regionale TRENORD 2431+ FRECCIAROSSA 9649 | 14:03 Domodossola station | 6h12 | 20:15 Rome Termini | 2 changes | |
Autobus TRENORD 4431A · Regionale TRENORD 2431+ 9993 | 14:03 Domodossola station | 7h02 | 21:05 Rome Termini | 2 changes | |
Autobus TRENORD 4431A · Regionale TRENORD 2431+ 9991 | 14:03 Domodossola station | 6h22 | 20:25 Rome Termini | 2 changes | |
Autobus TRENORD 4431A · Regionale TRENORD 2431+ 9955 | On time 14:03 Domodossola station | 7h16 | 21:19 Rome Termini | 2 changes | |
Autobus TRENORD 4433A · Regionale TRENORD 2433+ 9995 | On time 15:03 Domodossola station | 6h22 | 21:25 Rome Termini | 2 changes | |
Autobus TRENORD 4433A · Regionale TRENORD 2433+ 9997 | On time 15:03 Domodossola station | 7h02 | 22:05 Rome Termini | 2 changes | |
Autobus TRENORD 4433A · Regionale TRENORD 2433+ FRECCIAROSSA 9653 | 15:03 Domodossola station | 6h07 | 21:10 Rome Termini | 2 changes | |
Autobus TRENORD 4433A · Regionale TRENORD 2433+ 9959 | On time 15:03 Domodossola station | 7h17 | 22:20 Rome Termini | 2 changes | |
Autobus TRENORD 4235A · Regionale 10235+ 9963 | 15:21 Domodossola station | 9h03 | 0:24 Rome Termini | 2 changes | |
Autobus EC065+ 9997 | On time 15:30 Domodossola station | 6h35 | 22:05 Rome Termini | 1 change | |
FRECCIAROSSA 9657+ Autobus EC065 | 15:30 Domodossola station | 6h10 | 21:40 Rome Termini | 1 change | |
Autobus EC065+ 9995 | On time 15:30 Domodossola station | 5h55 | 21:25 Rome Termini | 1 change | |
Autobus EC065+ 9959 | On time 15:30 Domodossola station | 6h50 | 22:20 Rome Termini | 1 change | |
Autobus TRENORD 4435A · Regionale TRENORD 2435+ FRECCIAROSSA 9661 | 16:03 Domodossola station | 6h07 | 22:10 Rome Termini | 2 changes | |
Autobus TRENORD 4435A · Regionale TRENORD 2435+ 9961 | 16:03 Domodossola station | 7h21 | 23:24 Rome Termini | 2 changes | |
Autobus TRENORD 4435A · Regionale TRENORD 2435+ 9963 | 16:03 Domodossola station | 8h21 | 0:24 Rome Termini | 2 changes | |
Autobus TRENORD 4435A · Regionale TRENORD 2435+ 9963 | 16:03 Domodossola station | 8h21 | 0:24 Rome Termini | 2 changes | |
Autobus EC045+ 9961 | 16:30 Domodossola station | 6h54 | 23:24 Rome Termini | 1 change | |
Autobus EC045+ 9963 | 16:30 Domodossola station | 7h54 | 0:24 Rome Termini | 1 change | |
FRECCIAROSSA 9663+ Autobus EC045 | 16:30 Domodossola station | 6h09 | 22:39 Rome Termini | 1 change | |
Autobus TRENORD 4437A · Regionale TRENORD 2437+ 9963 | 17:03 Domodossola station | 7h21 | 0:24 Rome Termini | 2 changes | |
Autobus TRENORD 4437A · Regionale TRENORD 2437+ FRECCIAROSSA 9681 | 17:03 Domodossola station | 6h22 | 23:25 Rome Termini | 2 changes | |
Autobus TRENORD 4437A · Regionale TRENORD 2437+ 9963 | 17:03 Domodossola station | 7h21 | 0:24 Rome Termini | 2 changes | |
Regionale 11439+ InterCityNotte 797 | 18:48 Domodossola station | 11h32 | 6:20 Rome Ostiense | 1 change | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Domodossola to Rome by train, flight or coach
Compare train, flight and coach prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
19 Jun
20 Jun
21 Jun
22 Jun
23 Jun
24 Jun
25 Jun
Why should you book Domodossola to Rome trains with Omio?
Why book with Omio vs Italo?
- Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Frecciarossa, Intercity Notte, Intercity or Regionale to find the best option for your trip from Domodossola to Rome.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Italo with all available travel options, which are train, flight and bus to ensure you get the best deal for traveling from Domodossola to Rome.
Journey information
Overview: Train from Domodossola to Rome
Trains from Domodossola to Rome run on average 14 times per day, taking around 6h 39m. Cheap train tickets for this journey start at £24 if you book in advance.
The earliest train runs at 00:01, the last at 23:55. The fastest train covers the 577 km distance in 5h 18m.
Distance 577 km |
Average train duration 6h 39m |
Cheapest ticket price £24 |
Trains per day 14 |
Fastest train 5h 18m |
First train 0:01 |
Last train 23:55 |
Cheapest Month Oct |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Sat |
Best time to book 5 days |
Train companies: Italo, Frecciarossa, Intercity Notte, Intercity, Regionale, Trenord from Domodossola to Rome trainsItalo, Frecciarossa, Intercity Notte, Intercity, Regionale, Trenord trains will get you between Domodossola and Rome from £24. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Frecciarossa
Intercity Notte
Intercity
Regionale
Trenord
FAQs: Domodossola to Rome train
Find answers to the most common questions about traveling from Domodossola to Rome by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Domodossola and Rome
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, accessible from the main entrance
- Ristorante La Meridiana
- Osteria Vecchio Borgo
- Outside the main entrance
- Elevators, ramps
- €1
- Hotel Corona
- Hotel Ristorante Eurossola
- Hotel Domodossola
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for trains to Switzerland and regional destinations
- Train: Regional and Eurocity trains
- Bus: Several local lines available
- Mon - Sun: 06:30 - 22:00
- Free WiFi in the station
- Provided by KiPoint and located on Platform 24. Open every day from 06:00 to 23:00
- Acafe
- Moka Café
- Roadhouse Grill
- McDonald's
- Gusto
- Chef Express
- Coop Minimarket
- Mercato Centrale
- The Sala Blu, Trenitalia's office of assistance for disabled travelers, is located next to Platform 1
- Archi di Roma Guest House
- Gemma di Roma
- The Liberty Boutique Hotel
- Mon - Sun: 06:30 - 22:00
- Located near Platform 24
- Metro lines: A (red), B (blue)
- Bus lines: 5, H, 38, 40 Express, 50 Express, 64, 66, 70, 75, 82, 90 Express, 92, 105, 150F, 223, 310, 590, 714, 910, C2, C3
- Tram lines: 5, 14
- Train lines: Italo, FR, FA, FB, IC, ICN, EN, CNL, R, Leonardo Express
- Mon - Sun: 06:35 - 20:20
- Free, limited Wi-Fi available in the station for 15 minutes
- Luggage lockers are located in the station lobby
- Rock n’ Coffee Roma
- Arabian Kebab
- Ingredienti
- McDonald’s
- Numb's Bakery Café
- Accessible facilities include elevators and escalators
- B&B Rome Tiburtina
- B&B Alba Domus Roma
- Hotel delle Province
- Mon - Sun: 06:35 - 20:20
- Located inside the main terminal.
- Metro lines: LB
- Bus lines: 62, 71, 111, 111F, 120F, 135, 163, 168, 211, 309, 409, n409, n041, C2, C3, Airport Shuttle
- Train lines: FR, FA, IC, REG, FL1, FL2, FL3
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available near the station with both short-term and long-term options
- Ramen Bar Akira
- Eataly Roma
- Outside the main entrance
- Elevators, ramps, restrooms
- €1
- Hotel Abitart
- Hotel San Anselmo
- Hotel Villa San Pio
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-5 for regional and intercity trains
- Hall 2: platforms 6-11 for metropolitan services
- Metro: Line B
- Bus: Several lines available
- Tram: Line 3
Most popular train connections from Domodossola
More options for your journey from Domodossola to Rome
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