- Must visit
Museo Archeologico Regionale Paolo Orsi
Major archaeological museum with finds from prehistoric Sicily to the Greek and Roman eras; essential for understanding Syracuse.
Cheapest price
£83
Average price
£83
Fastest journey
12 h 15 m
Average duration
12 h 15 m
Buses per day
1
Distance
586 km
The best way to find a cheap coach ticket from Rome to Syracuse is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Rome to Syracuse will cost around £83 if you buy it on the day, but you can find cheap coach tickets today for only £83.
To travel from Rome to Syracuse you need to make at least one change.
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the train as it is the most popular option from Rome to Syracuse among Omio's users. If you are prioritising price take the flight with prices starting from £21. For those with little time consider booking a flight which can get you there in 1h 17m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a flight costs an average of £21, and a coach costs an average of £26.
Distance: 586 km
| Coach | Most popular Train | Flight |
|---|---|---|
£72 Average Price | £69 Average Price | £64 Average Price Cheapest |
12h 56m Average total duration 12h 26m Onboard + 30m Additional time* | 10h 23m Average total duration 9h 53m Onboard + 30m Additional time* | 4h 17m Average total duration Fastest 1h 17m Onboard + 3h 0m Additional time* |
0.6 - 1.5kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.8 - 3.5kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The table below shows live departures for Rome to Syracuse coaches for tomorrow, Monday 3 August. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 21:00 Roma, Autostazione Tiburtina | 12h15 | 9:15 Syracuse, Corso Umberto I | 1 change | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare coach, train and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Rome to Syracuse run on average 2 times per day, taking around 12h 26m. Cheap bus tickets for this journey start at £26 but you can travel from only £21 by flight.
The earliest coach runs at 00:45, the last at 23:55. The fastest coach covers the 586 km distance in 12h 0m.
Distance 586 km |
Average bus duration 12h 26m |
Cheapest ticket price £26 |
Buses per day 2 |
Fastest bus 12h 0m |
First bus 0:45 |
Last bus 23:55 |
Cheapest Month Oct |
Cheapest Day Sat |
High Season Jul - Sept |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Mon |
Best time to book 63 days |
Discover the best of Syracuse — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Syracuse trip today.
Major archaeological museum with finds from prehistoric Sicily to the Greek and Roman eras; essential for understanding Syracuse.
Gallery in Palazzo Bellomo showing medieval and early modern Sicilian art, including paintings, sculpture and decorative works.
Museum devoted to Archimedes and Leonardo, using models and interactive displays to explain inventions and scientific ideas.
Historic island quarter with lanes, sea views, markets and Baroque buildings; the best area for walking and absorbing the city.
Elegant square framed by the cathedral and palaces, especially appealing in the evening for architecture and atmosphere.
Large archaeological park combining Greek and Roman remains with quarry landscapes, shaded paths and key ancient sites.
Pasta with fresh sardines, wild fennel, pine nuts and raisins. A hallmark Sicilian dish balancing savoury and sweet coastal flavours.
Rice balls filled traditionally with ragù, peas and cheese, then breaded and fried. A classic Sicilian street food loved in Syracuse.
Thick Sicilian pizza topped with tomato, onion, anchovies, caciocavallo and breadcrumbs. Traditional, hearty and strongly regional.
Long-standing market venue famous for sandwiches, cured meats, cheeses and Sicilian products in a lively, informal atmosphere.
Popular Ortigia seafood restaurant known for fresh fish, pasta and a lively yet polished setting near the market area.
Established seafront restaurant in Ortigia serving refined Sicilian seafood dishes with views and a smart but relaxed atmosphere.
Moderate for Sicily. Dining and stays cost less than in Rome or Milan, but Ortigia tourist areas and summer prices raise accommodation and restaurant costs.
Service may be included via coperto. Rounding up or leaving 5-10% for good restaurant service is appreciated. Taxis are usually rounded up; cafés may get small change.
Official public transport app
Lungomare di Levante Elio Vittorini -> Piazza Archimede, Siracusa
Find answers to the most common questions about traveling from Rome to Syracuse by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Syracuse, this guide helps you travel smarter and with confidence.

Most Rome to Syracuse buses use the Roma, Autostazione Tiburtina to Syracuse, Corso Umberto I station pair. Use this guide to compare Rome and Syracuse bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need