Travel optionsfrom Rome to Karlsruhe
How to get to Karlsruhe from Rome by train, bus, flight or ferry.
Our recommendation
The best way to travel from Rome to Karlsruhe is by taking a coach because it’s the best combination of price and speed.
FlixBus16:3518h35Roma, Autostazione Tiburtina11:10Karlsruhe Hbf£471One-way0 changes
Cheapest
FlixBus16:3518h35Roma, Autostazione Tiburtina11:10Karlsruhe Hbf£471One-way0 changes
Fastest
LH237+
ICE 20518:354h24Rome Leonardo da Vinci Fiumicino Airport22:59Karlsruhe Hbf£2001One-way1 change
Other options
FlixBus · FlixBus10:4017h05Roma, Autostazione Tiburtina3:45Karlsruhe Hbf£621One-way1 change
FlixBus · FlixBus21:4517h50Roma, Autostazione Tiburtina15:35Karlsruhe Hbf£651One-way1 change
FlixBus · FlixBus0:1520h45Roma, Autostazione Tiburtina21:00Karlsruhe Hbf£651One-way1 change
EC2992+
ICE 20513:009h59Rome Leonardo da Vinci Fiumicino Airport22:59Karlsruhe Hbf£941One-way1 change
EC2992+
ICE 20313:007h59Rome Leonardo da Vinci Fiumicino Airport20:59Karlsruhe Hbf£1021One-way1 change
EC2992+
ICE 613 · ICE 37713:007h03Rome Leonardo da Vinci Fiumicino Airport20:03Karlsruhe Hbf£1041One-way2 changes
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Rome to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Rome to Karlsruhe.

- Around 13 coaches per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Rome and Karlsruhe as scheduled services by coach can vary by season or day of the week.
- Coaches mostly depart from Roma, Autostazione Tiburtina and arrive in Karlsruhe Hbf.
- Travel with FlixBus, Marino Autolinee to go to Karlsruhe by coach.
- 1 direct coaches per day with FlixBus.
Travelling from Rome to Karlsruhe: related information
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