Travel Information
Compare train, coach and flight for Pisa to Frankfurt am Main
Omio recommends booking the flight as it is the most popular option from Pisa to Frankfurt am Main among Omio's users. If you are prioritising price, take the coach, with an average ticket price of £100 For those with little time, consider booking a flight, which has an average total journey time of 4h 56m. If you are seeking to minimise your carbon footprint, the coach is your best option, with estimated CO2 emissions of 0.7 - 1.8kg. Average ticket prices depend on the travel mode: a coach costs an average of £100, while a flight costs an average of £484.
Distance: 723 km
Compare flight with
Most popular Flight | Coach | Driving |
|---|---|---|
£484 Average Price | £100 Average Price Cheapest | £211 Average Price (fuel + tolls) |
4h 56m Average total duration Fastest 2h 56m Onboard + 2h 0m Additional time* | 16h 59m Average total duration 16h 29m Onboard + 30m Additional time* | 10h 10m Average total duration (door-to-door) |
2.2 - 4.3kg CO2 emissions | 0.7 - 1.8kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Pisa to Frankfurt am Main:
A coach is £384 less than a flight for this route with tickets for a flight from Pisa to Frankfurt am Main costing on average £484.
Other travel options to Frankfurt am Main take longer:
Coach takes on average 16h 59m.
You'll arrive about 7h 14m sooner (2h 56m by flight vs 10h 10m by car). Tickets start at around £484 compared to roughly £211 in fuel and tolls — a bit more, but you get time back and avoid a long drive.
Driving makes more sense if you're travelling as a group, want flexibility on timing, or plan to stop en route.
Travel optionsfrom Pisa to Frankfurt am Main
How to get to Frankfurt am Main from Pisa by train, bus, flight or ferry.
Our recommendation
The best way to travel from Pisa to Frankfurt am Main is by taking a coach because it’s the best combination of price and speed.
FlixBus · FlixBus9:4019h50Pisa, Via delle Fiamme Gialle (Park Pietrasantina)5:30Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)£1011One-way1 change
Cheapest
FlixBus · FlixBus9:4019h50Pisa, Via delle Fiamme Gialle (Park Pietrasantina)5:30Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)£1011One-way1 change
Fastest
EN887318:351h40Pisa International Airport20:15Frankfurt am Main Airport£2151One-way0 changes
Other options
FlixBus · FlixBus17:1016h35Pisa, Via delle Fiamme Gialle (Park Pietrasantina)9:45Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)£1021One-way1 change
FlixBus · FlixBus9:4020h10Pisa, Via delle Fiamme Gialle (Park Pietrasantina)5:50Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)£1041One-way1 change
FlixBus · FlixBus · FlixBus7:1520h00Pisa, Via delle Fiamme Gialle (Park Pietrasantina)3:15Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)£1101One-way2 changes
LH740318:351h40Pisa International Airport20:15Frankfurt am Main Airport£2151One-way0 changes
BA615 · BA90812:505h30Pisa International Airport18:20Frankfurt am Main Airport£2611One-way1 change
BA615 · BA91012:509h50Pisa International Airport22:40Frankfurt am Main Airport£2611One-way1 change
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, coaches, flights and ferries
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Pisa to Frankfurt am Main
Travel to Frankfurt am Main easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Pisa to Frankfurt am Main.

This is compared to other travel options from Pisa to Frankfurt am Main:
A coach is £384 less than a flight for this route with tickets for a flight from Pisa to Frankfurt am Main costing on average £484.
Other travel options to Frankfurt am Main take longer:
Coach takes on average 16h 59m.
- Around 10 flights per day.
- Around 8 coaches per day.
However, we recommend checking specific travel dates for your route between Pisa and Frankfurt am Main as scheduled services by train, coach and flight can vary by season or day of the week.
- Flights mostly depart from Pisa International Airport and arrive in Frankfurt am Main Airport.
- Trains mostly depart from Pisa Centrale and arrive in Frankfurt Airport long-distance station.
- Coaches mostly depart from Pisa, Via delle Fiamme Gialle (Park Pietrasantina) and arrive in Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof).
- Travel with FlixBus to go to Frankfurt am Main by coach.
- Travel with British Airways, Transavia France, Air Dolomiti to go to Frankfurt am Main by flight.
- 3 direct flights per day with Air Dolomiti.
Travelling from Pisa to Frankfurt am Main: related information
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