Travel Information
Compare train, coach and flight for Pisa to Frankfurt am Main
Omio recommends booking the flight as it is the most popular option from Pisa to Frankfurt am Main among Omio's users. If you are prioritising price take the coach with prices starting from £53. For those with little time consider booking a flight which can get you there in 1h 35m. In case you are seeking to minimise your carbon footprint the coach is your best bet as it emits only 0.7 - 1.8kg. The ticket price range depends on the travel mode: a coach costs an average of £53, and a flight costs an average of £122.
Distance: 723 km
Compare flight with
Most popular Flight | Coach | Train |
|---|---|---|
£277 Average Price | £75 Average Price Cheapest | £225 Average Price |
4h 35m Average total duration Fastest 1h 35m Onboard + 3h 0m Additional time* | 16h 24m Average total duration 15h 54m Onboard + 30m Additional time* | 12h 6m Average total duration 11h 36m Onboard + 30m Additional time* |
2.2 - 4.3kg CO2 emissions | 0.7 - 1.8kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Pisa to Frankfurt am Main
How to get to Frankfurt am Main from Pisa by train, bus, flight or ferry.
Our recommendation
The best way to travel from Pisa to Frankfurt am Main is by taking a coach because it’s the best combination of price and speed.
FlixBus · FlixBus17:1018h20Pisa, Via delle Fiamme Gialle (Park Pietrasantina)11:30Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)£811One-way1 change
Cheapest
FlixBus · FlixBus17:1018h20Pisa, Via delle Fiamme Gialle (Park Pietrasantina)11:30Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)£811One-way1 change
Fastest
LH740318:401h40Pisa International Airport20:20Frankfurt am Main Airport£4661One-way0 changes
Other options
FlixBus · FlixBus · FlixBus7:1519h35Pisa, Via delle Fiamme Gialle (Park Pietrasantina)2:50Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)£831One-way2 changes
FlixBus · FlixBus · FlixBus17:1023h15Pisa, Via delle Fiamme Gialle (Park Pietrasantina)16:25Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)£881One-way2 changes
FlixBus · FlixBus23:3026h25Pisa, Aeroporto Parcheggio Aurelia1:55Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)£911One-way1 change
Regionale Veloce 4125 · Regionale 20443+
EC29945:3714h48Pisa Centrale20:25Frankfurt am Main Airport£1051One-way2 changes
InterCityNotte 799+
Regionale 20401+
EC29922:5612h04Pisa Centrale15:00Frankfurt am Main Airport£1151One-way2 changes
Intercity 505+
Regionale 20485+
EC299411:119h14Pisa Centrale20:25Frankfurt am Main Airport£1171One-way2 changes
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, coaches, flights and ferries
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FAQs: Pisa to Frankfurt am Main
Travel to Frankfurt am Main easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Pisa to Frankfurt am Main.

This is compared to other travel options from Pisa to Frankfurt am Main:
A coach is £150 less than a train for this route with tickets for a train from Pisa to Frankfurt am Main costing on average £225.
A coach is £202 less than a flight for this route with tickets for a flight from Pisa to Frankfurt am Main costing on average £277.
Other travel options to Frankfurt am Main take longer:
Train takes on average 11h 36m.
Coach takes on average 15h 54m.
- Around 10 coaches per day.
- Around 8 flights per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Pisa and Frankfurt am Main as scheduled services by train, coach and flight can vary by season or day of the week.
- Flights mostly depart from Pisa International Airport and arrive in Frankfurt am Main Airport.
- Coaches mostly depart from Pisa, Via delle Fiamme Gialle (Park Pietrasantina) and arrive in Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36).
- Travel with Trenitalia, Deutsche Bahn, Regionale to go to Frankfurt am Main by train.
- Travel with Air Dolomiti to go to Frankfurt am Main by flight.
- Travel with FlixBus to go to Frankfurt am Main by coach.
- 3 direct flights per day with Air Dolomiti.
Travelling from Pisa to Frankfurt am Main: related information
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