Travel Information
Compare train, coach, flight and ferry for Palermo to Siena
Omio recommends booking the coach as it is the most popular option from Palermo to Siena among Omio's users. If you are prioritising price take the flight with prices starting from £17. For those with little time consider booking a flight which can get you there in 1h 23m. The ticket price range depends on the travel mode: a flight costs an average of £17, and a train costs an average of £67.
Distance: 603 km
Compare bus with
Most popular Coach | Flight | Train |
|---|---|---|
£50 Average Price | £29 Average Price Cheapest | £112 Average Price |
17h 1m Average total duration 16h 31m Onboard + 30m Additional time* | 4h 23m Average total duration Fastest 1h 23m Onboard + 3h 0m Additional time* | 15h 2m Average total duration 14h 32m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Travel optionsfrom Palermo to Siena
How to get to Siena from Palermo by train, bus, flight or ferry.
Our recommendation
The best way to travel from Palermo to Siena is by taking a flight because it’s the best combination of price and speed.
FR 848522:301h20Palermo Airport23:50Pisa International Airport£201One-way0 changes
Cheapest
FR 848522:301h20Palermo Airport23:50Pisa International Airport£201One-way0 changes
Fastest
FR 848522:301h20Palermo Airport23:50Pisa International Airport£201One-way0 changes
Other options
InterCityNotte 1958+
FRECCIAROSSA 9524+
Regionale 1821121:0516h35Palermo Centrale13:40Siena station£1191One-way2 changes
InterCityNotte 1958+
Intercity 588+
Regionale 1908421:0518h17Palermo Centrale15:22Siena station£1191One-way2 changes
FlixBus15:2516h20Palermo, Via Tommaso Fazello (Terminal Bus)7:45Siena, Stazione FS (Piazzale Carlo Rosselli)£841One-way0 changes
FlixBus · FlixBus · FlixBus15:2523h25Palermo, Via Tommaso Fazello (Terminal Bus)14:50Siena, Siena/Viale Pietro Toselli£1081One-way2 changes
FlixBus · FlixBus9:1020h55Palermo, Via Tommaso Fazello (Terminal Bus)6:05Siena, Stazione FS (Piazzale Carlo Rosselli)£1181One-way1 change
FR 62558:001h20Palermo Airport9:20Pisa International Airport£201One-way0 changes
FR 844918:551h20Palermo Airport20:15Pisa International Airport£221One-way0 changes
XZ2710+
FlixBus7:109h50Palermo Airport17:00Siena, Stazione FS (Piazzale Carlo Rosselli)£421One-way1 change
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, coaches, flights and ferries
Compare train, coach, flight and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Palermo to Siena
Travel to Siena easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Palermo to Siena.

This is compared to other travel options from Palermo to Siena:
A flight is £12 less than a ferry for this route with tickets for a ferry from Palermo to Siena costing on average £41.
A flight is £21 less than a coach for this route with tickets for a coach from Palermo to Siena costing on average £50.
A flight is £83 less than a train for this route with tickets for a train from Palermo to Siena costing on average £112.
Other travel options to Siena take longer:
Train takes on average 14h 32m.
Coach takes on average 16h 31m.
Ferry takes on average 19h 51m.
- Around 30 flights per day.
- Around 4 coaches per day.
- Around 3 trains per day.
- Around 1 ferries per day.
However, we recommend checking specific travel dates for your route between Palermo and Siena as scheduled services by train, coach, flight and ferry can vary by season or day of the week.
- Flights mostly depart from Palermo Airport and arrive in Florence Peretola Airport.
- Trains mostly depart from Palermo Centrale and arrive in Siena station.
- Coaches mostly depart from Palermo, Via Tommaso Fazello (Terminal Bus) and arrive in Siena, Stazione FS (Piazzale Carlo Rosselli).
- Ferries mostly depart from Port of Palermo and arrive in Livorno (Terminal Grimaldi).
- Travel with Malta Air, Ryanair, Volotea to go to Siena by flight.
- Travel with FlixBus, Itabus to go to Siena by coach.
- Travel with Intercity to go to Siena by train.
- 3 direct flights per day with Malta Air, Ryanair, Volotea.
- 1 direct coaches per day with FlixBus.
Travelling from Palermo to Siena: related information
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