Travel Information
Compare coach, train, flight and ferry for Palermo to Siena
Omio recommends booking the coach as it is the most popular option from Palermo to Siena among Omio's users. If you are prioritising price take the coach with prices starting from £25. For those with little time consider booking a flight which can get you there in 1h 23m. The ticket price range depends on the travel mode: a coach costs an average of £25, and a flight costs an average of £16.
Distance: 603 km
Compare bus with
Most popular Coach | Flight | Train |
|---|---|---|
£54 Average Price Cheapest | £125 Average Price | £96 Average Price |
17h 1m Average total duration 16h 31m Onboard + 30m Additional time* | 4h 23m Average total duration Fastest 1h 23m Onboard + 3h 0m Additional time* | 15h 2m Average total duration 14h 32m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Travel optionsfrom Palermo to Siena
How to get to Siena from Palermo by train, bus, flight or ferry.
Our recommendation
The best way to travel from Palermo to Siena is by taking a train because it’s the best combination of price and speed.
InterCityNotte 1958+
Intercity 588+
Regionale 19084Cheapest
InterCityNotte 1958+
Intercity 588+
Regionale 19084Fastest
Intercity 736+
FRECCIAROSSA 1000 9556+
Regionale 18229Other options
Intercity 736+
8968+
TUSCANY LINE 18335 · Regionale 19059
InterCityNotte 1954+
FRECCIAROSSA 9516+
Regionale 18207
InterCityNotte 1958+
FRECCIAROSSA 9520+
Regionale 18209Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, coaches, flights and ferries
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FAQs: Palermo to Siena
Travel to Siena easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Palermo to Siena.

This is compared to other travel options from Palermo to Siena:
A flight is £10 less than a coach for this route with tickets for a coach from Palermo to Siena costing on average £25.
A flight is £23 less than a ferry for this route with tickets for a ferry from Palermo to Siena costing on average £39.
A flight is £43 less than a train for this route with tickets for a train from Palermo to Siena costing on average £58.
Other travel options to Siena take longer:
Train takes on average 14h 34m.
Coach takes on average 16h 20m.
Ferry takes on average 19h 30m.
- Around 30 flights per day.
- Around 4 coaches per day.
- Around 3 trains per day.
- Around 1 ferries per day.
However, we recommend checking specific travel dates for your route between Palermo and Siena as scheduled services by coach, train, flight and ferry can vary by season or day of the week.
- Ferries mostly depart from Port of Palermo and arrive in Port of Livorno.
- Flights mostly depart from Palermo Airport and arrive in Florence Peretola Airport.
- Trains mostly depart from Palermo Centrale and arrive in Siena station.
- Coaches mostly depart from Palermo, Via Tommaso Fazello (Terminal Bus) and arrive in Siena, Stazione FS (Piazzale Carlo Rosselli).
- Travel with FlixBus, Itabus to go to Siena by coach.
- Travel with Intercity to go to Siena by train.
- Travel with Ryanair, KM Malta Airlines, Volotea to go to Siena by flight.
- 1 direct coaches per day with FlixBus.
- 3 direct flights per day with Ryanair, KM Malta Airlines, Volotea.
Travelling from Palermo to Siena: related information
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