The cheapest and fastest trains from Venice Mestre to Siena station
Cheapest price
£23
Average price
£23
Fastest journey
5 h 10 m
Average duration
5 h 10 m
Trains per day
1
Distance
250 km
The best way to find a cheap train ticket from Venice Mestre to Siena station is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Venice Mestre to Siena station will cost around £23 if you buy it on the day, but you can find cheap train tickets today for only £23.
Of the 1 trains that leave Venice Mestre for Siena station every day 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct trains cover the 250 km distance in an average of 5 h 10 m but if you time it right, some trains will get you there in just 5 h 10 m .
The slowest trains will take 5 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare coach and train for Venice Mestre to Siena station
Omio recommends booking the train as it is the most popular option from Venice Mestre to Siena station among Omio's users. If you are prioritising price take the coach with prices starting from £8. For those with little time consider booking a train which can get you there in 4h 5m. The ticket price range depends on the travel mode: a coach costs an average of £8, and a train costs an average of £29.
Distance: 250 km
Compare train with
Most popular Train | Coach |
|---|---|
£41 Average Price | £14 Average Price Cheapest |
4h 35m Average total duration Fastest 4h 5m Onboard + 30m Additional time* | 5h 10m Average total duration 4h 40m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Compare prices and tickets Venice Mestre to Siena station by coach or train
Compare coach and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
20 Nov
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26 Nov
Journey information
Overview: Train from Venice Mestre to Siena station
Trains from Venice Mestre to Siena station run on average 14 times per day, taking around 4h 5m. Cheap train tickets for this journey start at £29 but you can travel from only £8 by coach.
The earliest train runs at 03:38, the last at 20:17. The fastest train covers the 250 km distance in 4h 0m.
Distance 250 km |
Average train duration 4h 5m |
Cheapest ticket price £29 |
Trains per day 14 |
Fastest train 4h 0m |
First train 03:38 |
Last train 20:17 |
Train companies: Frecciarossa, Italo, Intercity, Regionale from Venice Mestre to Siena station trainsFrecciarossa, Italo, Intercity, Regionale trains will get you between Venice Mestre and Siena station from £8. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Frecciarossa
Italo
Intercity
Regionale
FAQs: Venice Mestre to Siena station train
Find answers to the most common questions about traveling from Venice Mestre to Siena station by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Siena station, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Venice Mestre and Siena station
- Mon - Sun: 05:50 - 20:30
- Provided by KiPoint and located on the ground floor.
- McDonald’s
- Chock Full O'Nuts
- Puro Gusto
- Juice Bar
- Rossosapore
- Full accessibility facilities, including toilets, ramps, wheelchairs, elevators and a mobility assistance center.
- Best Western Hotel Tritone
- The Plaza Hotel
- Hotel Villa Constanza
- Mon - Sun: 05:50 - 20:30
- Located in the main concourse.
- Bus lines: 2, 3, 10, 15, 18, 25a, 31, 31H, 32, 32H, 33H, 34H, 43, 53, 86, N1, 8AE
- Train lines: FR, FA, FB, EC, RJ, IC, EN, ICN, R, Italo
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- Parking is available near the station, open 24/7.
- Ristorante Il Vinaio
- Osteria Le Logge
- Outside the main entrance.
- Elevators, ramps.
- €1
- Hotel Italia
- NH Siena
- Hotel Minerva
- Located near the main entrance
- Located near the main entrance
- Free
- The station has a single-level layout with platforms accessible from the main hall.
- Bus: Several local and regional lines available
- Taxi: Available outside the station
More options for your journey from Venice Mestre to Siena station
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