The cheapest and fastest trains from Siena station to Venice Mestre
Cheapest price
£27
Average price
£27
Fastest journey
9 h 50 m
Average duration
9 h 50 m
Trains per day
1
Distance
250 km
The best way to find a cheap train ticket from Siena station to Venice Mestre is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Siena station to Venice Mestre will cost around £27 if you buy it on the day, but you can find cheap train tickets today for only £27.
Of the 1 trains that leave Siena station for Venice Mestre every day 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct trains cover the 250 km distance in an average of 9 h 50 m but if you time it right, some trains will get you there in just 9 h 50 m .
The slowest trains will take 9 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare coach and train for Siena station to Venice Mestre
Omio recommends booking the train as it is the most popular option from Siena station to Venice Mestre among Omio's users. If you are prioritising price take the coach with prices starting from £6. For those with little time consider booking a train which can get you there in 3h 58m. The ticket price range depends on the travel mode: a coach costs an average of £6, and a train costs an average of £18.
Distance: 250 km
Compare train with
Most popular Train | Coach |
|---|---|
£33 Average Price | £12 Average Price Cheapest |
4h 28m Average total duration Fastest 3h 58m Onboard + 30m Additional time* | 5h 0m Average total duration 4h 30m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Siena station to Venice Mestre train times
The table below shows live departures for Siena station to Venice Mestre trains for today, Tuesday 3 February. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
Regionale 18222+ FRECCIAROSSA 1000 9420 | 11:18 Siena station | 4h05 | 15:23 Venice Mestre | 1 change | |
Regionale 18224+ Intercity 590+ Regionale Veloce 3986 | 12:18 Siena station | 5h49 | 18:07 Venice Mestre | 2 changes | |
Regionale 18224+ FRECCIAROSSA 9422 | 12:18 Siena station | 4h05 | 16:23 Venice Mestre | 1 change | |
Regionale 18226+ FRECCIAROSSA 1000 9423 | 13:18 Siena station | 4h05 | 17:23 Venice Mestre | 1 change | |
Regionale 18228+ FRECCIAROSSA 9426 | 14:18 Siena station | 4h05 | 18:23 Venice Mestre | 1 change | |
Regionale 18232+ Intercity 592 | 15:18 Siena station | 5h18 | 20:36 Venice Mestre | 1 change | |
Regionale 18232+ FRECCIAROSSA 9428 | 15:18 Siena station | 4h05 | 19:23 Venice Mestre | 1 change | |
Regionale 19044 · Regionale 18312+ Intercity 592 | 15:41 Siena station | 4h55 | 20:36 Venice Mestre | 2 changes | |
Regionale 18234+ Intercity 596+ Regionale Veloce 3992 | 16:18 Siena station | 5h49 | 22:07 Venice Mestre | 2 changes | |
Regionale 18234+ FRECCIAROSSA 1000 9430 | 16:18 Siena station | 4h05 | 20:23 Venice Mestre | 1 change | |
Regionale 18236+ FRECCIAROSSA 9432 | 17:18 Siena station | 4h24 | 21:42 Venice Mestre | 1 change | |
Regionale 18238+ FRECCIAROSSA 1000 9434 | 18:18 Siena station | 4h05 | 22:23 Venice Mestre | 1 change | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Siena station to Venice Mestre by coach or train
Compare coach and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
04 Feb
05 Feb
06 Feb
07 Feb
08 Feb
09 Feb
10 Feb
Journey information
Overview: Train from Siena station to Venice Mestre
Trains from Siena station to Venice Mestre run on average 16 times per day, taking around 3h 58m. Cheap train tickets for this journey start at £23 but you can travel from only £6 by coach.
The earliest train runs at 04:25, the last at 19:40. The fastest train covers the 250 km distance in 4h 5m.
Distance 250 km |
Average train duration 3h 58m |
Cheapest ticket price £23 |
Trains per day 16 |
Fastest train 4h 5m |
First train 04:25 |
Last train 19:40 |
Train companies: Italo, Frecciarossa, Intercity, Regionale from Siena station to Venice Mestre trainsItalo, Frecciarossa, Intercity, Regionale trains will get you between Siena station and Venice Mestre from £6. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Frecciarossa
Intercity
Regionale
FAQs: Siena station to Venice Mestre train
Find answers to the most common questions about traveling from Siena station to Venice Mestre by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Venice Mestre, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Siena station and Venice Mestre
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- Parking is available near the station, open 24/7.
- Ristorante Il Vinaio
- Osteria Le Logge
- Outside the main entrance.
- Elevators, ramps.
- €1
- Hotel Italia
- NH Siena
- Hotel Minerva
- Located near the main entrance
- Located near the main entrance
- Free
- The station has a single-level layout with platforms accessible from the main hall.
- Bus: Several local and regional lines available
- Taxi: Available outside the station
- Mon - Sun: 05:50 - 20:30
- Provided by KiPoint and located on the ground floor.
- McDonald’s
- Chock Full O'Nuts
- Puro Gusto
- Juice Bar
- Rossosapore
- Full accessibility facilities, including toilets, ramps, wheelchairs, elevators and a mobility assistance center.
- Best Western Hotel Tritone
- The Plaza Hotel
- Hotel Villa Constanza
- Mon - Sun: 05:50 - 20:30
- Located in the main concourse.
- Bus lines: 2, 3, 10, 15, 18, 25a, 31, 31H, 32, 32H, 33H, 34H, 43, 53, 86, N1, 8AE
- Train lines: FR, FA, FB, EC, RJ, IC, EN, ICN, R, Italo
Most popular train connections from Siena station
More options for your journey from Siena station to Venice Mestre
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